Dietary supplement with vitamin C prevents nitrate tolerance

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grynkiewicz, G., Poenie, M., & Tsien, R. Y. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83641-4 · Cited by 21,722 · see citing works

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Polazzi, E., Mengoni, I., Caprini, M., Peña‐Altamira, E., Kurtys, E., & Monti, B. (2012) · Neurosignals · doi:10.1159/000337115 · Cited by 9,023 · see citing works

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

Rajagopalan, S., Kurz, S. D., Münzel, T. F., Tarpey, M. M., Freeman, B. Α., Griendling, K. K., & Harrison, D. G. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118623 · Cited by 2,441 · see citing works

Antioxidants and Atherosclerotic Heart Disease

Diaz, M. N., Frei, B. B., Vita, J. A., & Keaney, J. F. (1997) · New England Journal of Medicine · doi:10.1056/nejm199708073370607 · Cited by 1,353 · see citing works

Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus.

Ting, H. H., Timimi, F. K., Boles, K., Creager, S. J., Ganz, P., & Creager, M. A. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118394 · Cited by 869 · see citing works

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

Beckman, J. S., Ischiropoulos, H., Zhu, L., van der Woerd, M., Smith, C. D. L., Chen, J., Harrison, J. G., Martin, J. C., & Tsai, M. (1992) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(92)90432-v · Cited by 765 · see citing works

Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance.

Münzel, T. F., Sayegh, H. S., Freeman, B. Α., Tarpey, M. M., & Harrison, D. G. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117637 · Cited by 652 · see citing works

Ascorbic Acid Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease

Levine, G. N., Frei, B., Koulouris, S. N., Gerhard, M. D., Keaney, J. F., & Vita, J. A. (1996) · Circulation · doi:10.1161/01.cir.93.6.1107 · Cited by 582 · see citing works

Antioxidant Vitamin C Improves Endothelial Dysfunction in Chronic Smokers

Heitzer, T., Just, H., & Mu¨nzel, T. (1996) · Circulation · doi:10.1161/01.cir.94.1.6 · Cited by 554 · see citing works

Vitamin C Improves Endothelium-Dependent Vasodilation in Forearm Resistance Vessels of Humans With Hypercholesterolemia

Ting, H. H., Timimi, F. K., Haley, E. A., Roddy, M.-A., Ganz, P., & Creager, M. A. (1997) · Circulation · doi:10.1161/01.cir.95.12.2617 · Cited by 355 · see citing works

Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug.

Münzel, T. F., Kurz, S. D., Rajagopalan, S., Thoenes, M., Berrington, W. R., Thompson, J. A., Freeman, B. Α., & Harrison, D. G. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118935 · Cited by 313 · see citing works

Vitamin C Improves Endothelial Dysfunction of Epicardial Coronary Arteries in Hypertensive Patients

Solzbach, U., Hornig, B., Jeserich, M., & Just, H. (1997) · Circulation · doi:10.1161/01.cir.96.5.1513 · Cited by 278 · see citing works

Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti- rather than prooxidant activity of vitamin c in the presence of transition metal ions

Retsky, K. L., Freeman, M. W., & Frei, B. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54075-8 · Cited by 271 · see citing works

Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance.

Münzel, T. F., Giaid, A., Kurz, S. D., Stewart, D. J., & Harrison, D. G. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.11.5244 · Cited by 176 · see citing works

Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo.

Lehr, H. A., Frei, B., & Arfors, K. E. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.16.7688 · Cited by 167 · see citing works

Difference in nitroglycerin dose-response in the venous and arterial beds

Imhof, P. R., Ott, B., Frankhauser, P., Chu, L. C., & Hodler, J. (1980) · European Journal of Clinical Pharmacology · doi:10.1007/bf00874655 · Cited by 160 · see citing works

Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking.

Lehr, H. A., Weyrich, A. S., Saetzler, R. K. E., Jurek, A., Arfors, K. ‐., Zimmerman, G. A., Prescott, S. M., & McIntyre, T. M. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119417 · Cited by 158 · see citing works

Vitamins C and E Inhibit O 2 − Production in the Pig Coronary Artery

Nunes, G. L., Robinson, K. A., Kalynych, A. M., King, S. B., Sgoutas, D. S., & Berk, B. C. (1997) · Circulation · doi:10.1161/01.cir.96.10.3593 · Cited by 149 · see citing works

Randomized, Double-Blind, Placebo-Controlled Study of Supplemental Vitamin E on Attenuation of the Development of Nitrate Tolerance

Watanabe, H., Kakihana, M., Ohtsuka, S., & Sugishita, Y. (1997) · Circulation · doi:10.1161/01.cir.96.8.2545 · Cited by 99 · see citing works

[3] Analysis of ascorbic acid by liquid chromatography with amperometric detection

Pachla, L. A., & Kissinger, P. T. (1979) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(79)62183-3 · Cited by 97 · see citing works

Nitrate tolerance in epicardial arteries or in the venous system is not reversed by N-acetylcysteine in vivo, but tolerance-independent interactions exist.

Münzel, T. F., Holtz, J., Mülsch, A., Stewart, D. J., & Bassenge, E. (1989) · Circulation · doi:10.1161/01.cir.79.1.188 · Cited by 93 · see citing works

Unexpected, Tolerance-Devoid Vasomotor and Platelet Actions of Pentaerythrityl Tetranitrate

Fink, B., & Bassenge, E. (1997) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199712000-00020 · Cited by 70 · see citing works

Long-term Angiotensin-Converting Enzyme Inhibition With High-Dose Enalapril Retards Nitrate Tolerance in Large Epicardial Arteries and Prevents Rebound Coronary Vasoconstriction In Vivo

Münzel, T. F., & Bassenge, E. (1996) · Circulation · doi:10.1161/01.cir.93.11.2052 · Cited by 65 · see citing works

Soluble guanylate cyclase activation by nitric oxide and its reversal

Braughler, J. M. (1983) · Biochemical Pharmacology · doi:10.1016/0006-2952(83)90581-6 · Cited by 64 · see citing works

Direct inhibition of platelet function by organic nitrates via nitric oxide formation

Weber, A., Strobach, H., & Schrör, K. (1993) · European Journal of Pharmacology Molecular Pharmacology · doi:10.1016/0922-4106(93)90134-u · Cited by 59 · see citing works

Effects of selenium, vitamin E and vitamin C on human prostacyclin and thromboxane synthesis

Toivanen, J. (1987) · Prostaglandins Leukotrienes and Medicine · doi:10.1016/0262-1746(87)90036-9 · Cited by 57 · see citing works

Tolerance to nitrates and simultaneous upregulation of platelet activity prevented by enhancing antioxidant state

Bassenge, E., & Fink, B. (1996) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/bf00168641 · Cited by 50 · see citing works

Effects of nitric oxide-containing compounds on increases in cytosolic ionized Ca2+ and on aggregation of human platelets

Ivanova, K., Schaefer, M., Drummer, C., et al. (1993) · European Journal of Pharmacology Molecular Pharmacology · doi:10.1016/0922-4106(93)90057-g · Cited by 46 · see citing works

Urinary Nitrotyrosine Content as a Marker of Peroxynitrite-induced Tolerance to Organic Nitrates

Skatchkov, M. P., Larina, L. L., Larin, A. A., Fink, N., & Bassenge, E. (1997) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/107424849700200202 · Cited by 39 · see citing works

Vitamin C increases the prostacyclin production and decreases the vascular lesions in experimental atherosclerosis in rabbits

Beetens, J. R., Coene, M. C., Verheyen, A., Zonnekeyn, L. L., & Herman, A. G. (1986) · Prostaglandins · doi:10.1016/0090-6980(86)90003-1 · Cited by 31 · see citing works

Sustained Antiplatelet Properties of Nitroglycerin During Hemodynamic Tolerance in Rats

Booth, B. P., Jacob, S., Bauer, J. A., et al. (1996) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199609000-00013 · Cited by 27 · see citing works

Membrane fluidity of non-activated and activated human blood platelets

Feijge, M. A. H., Heemskerk, J. W. M., & Hornstra, G. (1990) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(90)90095-6 · Cited by 21 · see citing works

Use of nitrates in ischemic heart disease

Abrams, J. (1992) · Current Problems in Cardiology · doi:10.1016/0146-2806(92)90008-c · Cited by 18 · see citing works

Comparison of the effects of two different galenical preparations of glyceryl trinitrate on pulmonary artery pressure and on the finger pulse curve

Buschmann, M., Wiegand, A., Schnellbacher, K., Bonn, R., Rehe, A., Trenk, D., J�hnchen, E., & Roskamm, H. (1993) · European Journal of Clinical Pharmacology · doi:10.1007/bf00315542 · Cited by 17 · see citing works

Nitrate therapy in patients with coronary artery disease--preparations and doses with and without development of tolerance.

Rudolph, W., Dirschinger, J., Kraus, F., et al. (1990) · PubMed · Cited by 12 · see citing works

Angiotensin II Receptor Regulates Ionic Currents in Guinea Pig Ventricular Myocytes

Yang, X., & Jiang, W. (1998) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/107424849800300101 · Cited by 3 · see citing works

Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention

Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J.-H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., et al. (2003) · Journal of the American College of Nutrition · doi:10.1080/07315724.2003.10719272 · Cited by 1,949 · see citing works

Nitric oxide donors: chemical activities and biological applications

Wang, P. G., Xian, M., Tang, X., Wu, X., Wen, Z., Cai, T., & Janczuk, A. J. (2002) · Chemical Reviews · doi:10.1021/cr000040l · Cited by 1,337 · see citing works

Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases

Bjelakovic, G., Nikolova, D., Gluud, L. L., Simonetti, R. G., & Gluud, C. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007176.pub2 · Cited by 924 · see citing works

Vitamin C-Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination

Doseděl, M., Jirkovský, E., Macáková, K., Krčmová, L., Javorská, L., Pourová, J., Mercolini, L., Remião, F., Nováková, L., Mladěnka, P., et al. (2021) · Nutrients · doi:10.3390/nu13020615 · Cited by 553 · see citing works

Explaining the Phenomenon of Nitrate Tolerance

Münzel, T., Daiber, A., & Mülsch, A. (2005) · Circulation Research · doi:10.1161/01.res.0000184694.03262.6d · Cited by 424 · see citing works

Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species

Daiber, A. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2010.01.032 · Cited by 347 · see citing works

Physiology and Pathophysiology of Vascular Signaling Controlled by Cyclic Guanosine 3′,5′-Cyclic Monophosphate–Dependent Protein Kinase

Münzel, T., Feil, R., Mülsch, A., Lohmann, S. M., Hofmann, F., & Walter, U. (2003) · Circulation · doi:10.1161/01.cir.0000094403.78467.c3 · Cited by 316 · see citing works

Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance

Sydow, K., Daiber, A., Oelze, M., Chen, Z., August, M., Wendt, M., Ullrich, V., Mülsch, A., Schulz, E., Keaney, J. F., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200419267 · Cited by 300 · see citing works

How does ascorbic acid prevent endothelial dysfunction?

May, J. M. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00269-0 · Cited by 260 · see citing works

Folic Acid Prevents Nitroglycerin-Induced Nitric Oxide Synthase Dysfunction and Nitrate Tolerance: A Human In Vivo Study

Gori, T., Burstein, J. M., Ahmed, S., Miner, S. E. S., Al-Hesayen, A., Kelly, S., & Parker, J. D. (2001) · Circulation · doi:10.1161/hc3501.095358 · Cited by 178 · see citing works

Vitamin C and myocardial infarction: the heart of the matter3

Padayatty, S. J., & Levine, M. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.5.1027 · Cited by 18 · see citing works

Which drug for which orthostatic hypotension?

Sénard, J., & Montastruc, J. (1996) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.1996.tb00301.x · Cited by 14 · see citing works

[Intractable Orthostatic Hypotension in Patients with Parkinson's Disease: General Matters about Orthostatic Hypotension and Cautionary Notes through Our Observed Refractory Cases].

Ishihara, T. (2022) · PubMed · doi:10.11477/mf.1416202099 · Cited by 1 · see citing works

Orthostatic Intolerance and Orthostatic (Postural) Hypotension

Grubb, B. P. (2007) · doi:10.1002/9780470750902.ch5

Syncope and orthostatic hypotension

Atkins, D., Hanusa, B. H., Sefcik, T., & Kapoor, W. N. (1991) · The American Journal of Medicine · doi:10.1016/0002-9343(91)90012-m · Cited by 169 · see citing works

Overlooking orthostatic hypotension with routine blood-pressure equipment

Caine, S., Alsop, K., & Mahon, M. M. (1998) · The Lancet · doi:10.1016/s0140-6736(05)79194-7 · Cited by 22 · see citing works