Decreased Presynaptic Dopamine Function in the Left Caudate of Depressed Patients With Affective Flattening and Psychomotor Retardation

A new depression scale designed to be sensitive to change

Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Generalizations

Patlak, C. S., & Blasberg, R. G. (1985) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1985.87 · Cited by 1,673

Dopamine, schizophrenia, mania, and depression: Toward a unified hypothesis of cortico-striatopallido-thalamic function

Swerdlow, N. R., & Koob, G. F. (1987) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00047488 · Cited by 674

Cerebral Metabolic Rates for Glucose in Mood Disorders

Baxter, L. R. (1985) · Archives of General Psychiatry · doi:10.1001/archpsyc.1985.01790280019002 · Cited by 602

Regional cerebral blood flow in depression measured by positron emission tomography: the relationship with clinical dimensions

Bench, C. J., Friston, K. J., Brown, R. G., Frackowiak, R. S. J., & Dolan, R. J. (1993) · Psychological Medicine · doi:10.1017/s0033291700025368 · Cited by 530

The brief scale for anxiety: a subdivision of the comprehensive psychopathological rating scale.

Tyrer, P. J., Owen, R. T., & Cicchetti, D. (1984) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.47.9.970 · Cited by 277

Depressive symptoms and presynaptic dopamine function in neuroleptic-naive schizophrenia

Hietala, J. A., Syvälahti, E. K. G., Vilkman, H., Vuorio, K. A., Räkköläinen, V., Bergman, J. R., Haaparanta‐Solin, M., Solin, O. H., Kuoppamäki, M., Eronen, E., et al. (1999) · Schizophrenia Research · doi:10.1016/s0920-9964(98)00113-3 · Cited by 247

Differential Mood Changes Following Basal Ganglia vs Thalamic Lesions

STARKSTEIN, S. E., Robinson, R. G., Berthier, M. L., Parikh, R. M., & Price, T. R. (1988) · Archives of Neurology · doi:10.1001/archneur.1988.00520310031013 · Cited by 164

Presynaptic dopaminergic function in the striatum of schizophrenic patients

Dao-Castellana, M. H., Martinot, M. P., Hantraye, P., Attar-Levy, D., Rémy, P., Crouzel, C., Artiges, É., Féline, A., Syrota, A., & Martinot, J. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(96)00102-8 · Cited by 160

Retarded depression and the dopamine metabolism

van Praag, H. M., & Korf, J. (1971) · Psychopharmacology · doi:10.1007/bf00402643 · Cited by 138

Cytokines sing the blues: inflammation and the pathogenesis of depression

Raison, C. L., Capuron, L., & Miller, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2005.11.006 · Cited by 3,009

The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway

Howes, O. D., & Kapur, S. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp006 · Cited by 2,693

Reconsidering anhedonia in depression: Lessons from translational neuroscience

Treadway, M. T., & Zald, D. H. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.06.006 · Cited by 1,579

Neuroimaging studies of mood disorders

Drevets, W. C. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01020-9 · Cited by 1,334

The role of dopamine in the pathophysiology of depression

Dunlop, B. W., & Nemeroff, C. B. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.3.327 · Cited by 1,244

The Psychobiology of Depression and Resilience to Stress: Implications for Prevention and Treatment

Southwick, S. M., Vythilingam, M., & Charney, D. S. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.143948 · Cited by 1,160

Elevated Striatal Dopamine Function Linked to Prodromal Signs of Schizophrenia

Howes, O. D., Montgomery, A. J., Asselin, M.-C., Murray, R. M., Valli, I., Tabraham, P., Bramon-Bosch, E., Valmaggia, L., Johns, L., Broome, M., et al. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.514 · Cited by 744

Cytokines and psychopathology: Lessons from interferon-α

Capuron, L., & Miller, A. H. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.02.009 · Cited by 562

Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application

Millan, M. J. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.11.006 · Cited by 567

Inflammation Effects on Motivation and Motor Activity: Role of Dopamine

Felger, J. C., & Treadway, M. T. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.143 · Cited by 471

Psychomotor retardation in depression: Biological underpinnings, measurement, and treatment

Close, J. S., McClintock, S. M., & Croarkin, P. E. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.10.019 · Cited by 401

Peripheral inflammation is associated with altered substantia nigra activity and psychomotor slowing in humans

Brydon, L., Harrison, N. A., Walker, C., Steptoe, A., & Critchley, H. D. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.12.007 · Cited by 381

Mood Disorders in Everyday Life: A Systematic Review of Experience Sampling and Ecological Momentary Assessment Studies

aan het Rot, M., Hogenelst, K., & Schoevers, R. A. (2012) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.05.007 · Cited by 325

Serotonin 5-HT2C Receptors as a Target for the Treatment of Depressive and Anxious States: Focus on Novel Therapeutic Strategies

Millan, M. J. (2005) · Therapies · doi:10.2515/therapie:2005065 · Cited by 296

Striatal Presynaptic Dopamine in Schizophrenia, Part II: Meta-Analysis of [18F/11C]-DOPA PET Studies

Fusar‐Poli, P., & Meyer‐Lindenberg, A. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr180 · Cited by 267

Mechanisms of cytokine-induced behavioral changes: psychoneuroimmunology at the translational interface

Miller, A. H. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2008.08.006 · Cited by 261

Presynaptic Striatal Dopamine Dysfunction in People at Ultra-high Risk for Psychosis: Findings in a Second Cohort

Egerton, A., Chaddock, C. A., Winton-Brown, T. T., Bloomfield, M. A. P., Bhattacharyya, S., Allen, P., McGuire, P. K., & Howes, O. D. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.11.017 · Cited by 253

Psychomotor Retardation in Depression: A Systematic Review of Diagnostic, Pathophysiologic, and Therapeutic Implications

Bennabi, D., Vandel, P., Papaxanthis, C., Pozzo, T., & Haffen, É. (2013) · BioMed Research International · doi:10.1155/2013/158746 · Cited by 285

Psychomotor symptoms in depression: A diagnostic, pathophysiological and therapeutic tool

Schrijvers, D. L., Hulstijn, W., & Sabbe, B. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.10.019 · Cited by 245

Tobacco smoking as a risk factor for major depressive disorder: population-based study

Pasco, J. A., Williams, L. J., Jacka, F. N., Ng, F., Henry, M. J., Nicholson, G. C., Kotowicz, M. A., & Berk, M. (2008) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.107.046706 · Cited by 233

Probing Brain Reward System Function in Major Depressive Disorder: Altered Response to Dextroamphetamine

Tremblay, L. K., Naranjo, C. A., Cardenas, L., Herrmann, N., & Busto, U. E. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.5.409 · Cited by 229

Midbrain dopamine function in schizophrenia and depression: A post-mortem and positron emission tomographic imaging study

Howes, O. D., Williams, M., Ibrahim, K., Leung, G., Egerton, A., McGuire, P. K., & Turkheimer, F. (2013) · Brain · doi:10.1093/brain/awt264 · Cited by 198

Stratified medicine for mental disorders

Schumann, G., Binder, E. B., Holte, A., de Kloet, E. R., Oedegaard, K. J., Robbins, T. W., Walker-Tilley, T. R., Bitter, I., Brown, V. J., Buitelaar, J., et al. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.09.010 · Cited by 186

The role of inflammation in core features of depression: Insights from paradigms using exogenously-induced inflammation.

Dooley, L. N., Kuhlman, K. R., Robles, T. F., Eisenberger, N. I., Craske, M. G., & Bower, J. E. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.09.006 · Cited by 176

Neurobiology of Chronic Stress-Related Psychiatric Disorders: Evidence from Molecular Imaging Studies

Davis, M. T., Holmes, S. E., Pietrzak, R. H., & Esterlis, I. (2017) · Chronic Stress · doi:10.1177/2470547017710916 · Cited by 191

Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia.

Hope, S., Dieset, I., Agartz, I., Steen, N. E., Ueland, T., Melle, I., Aukrust, P., & Andreassen, O. A. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.08.003 · Cited by 164

Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis

Howes, O. D., Montgomery, A. J., Asselin, M., Murray, R. M., Grasby, P. M., & McGuire, P. K. (2007) · The British Journal of Psychiatry · doi:10.1192/bjp.191.51.s13 · Cited by 144

Neural indicators of error processing in generalized anxiety disorder, obsessive-compulsive disorder, and major depressive disorder.

Weinberg, A., Kotov, R., & Proudfit, G. H. (2014) · Journal of Abnormal Psychology · doi:10.1037/abn0000019 · Cited by 156

Inflammatory markers are associated with decreased psychomotor speed in patients with major depressive disorder

Goldsmith, D. R., Haroon, E., Woolwine, B. J., Jung, M. Y., Wommack, E. C., Harvey, P. D., Treadway, M. T., Felger, J. C., & Miller, A. H. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.03.025 · Cited by 142

Interoception and Inflammation in Psychiatric Disorders

Savitz, J., & Harrison, N. A. (2018) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2017.12.011 · Cited by 126

IFN-alpha-induced motor slowing is associated with increased depression and fatigue in patients with chronic hepatitis C

Majer, M., Welberg, L. A. M., Capuron, L., Pagnoni, G., Raison, C. L., & Miller, A. H. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.12.009 · Cited by 124

The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review

Dahoun, T., Trossbach, S. V., Brandon, N., Korth, C., & Howes, O. (2017) · Translational Psychiatry · doi:10.1038/tp.2016.282 · Cited by 118

Dopamine Type-1 Receptor Binding in Major Depressive Disorder Assessed Using Positron Emission Tomography and [11C]NNC-112

Cannon, D. M., Klaver, J. M., Peck, S. A., Rallis, D., Erickson, K., & Drevets, W. C. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.194 · Cited by 119

Depression, Anhedonia, and Psychomotor Symptoms:The Role of Dopaminergic Neurocircuitry

Stein, D. J. (2008) · CNS Spectrums · doi:10.1017/s1092852900016837 · Cited by 112

Psychomotor slowing as a predictor of fluoxetine nonresponse in depressed outpatients

Taylor, B. P., Bruder, G. E., Stewart, J. W., McGrath, P. J., Halperin, J., Ehrlichman, H., & Quitkin, F. M. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.1.73 · Cited by 109

Psychomotor retardation in depression: A critical measure of the forced swim test

Ünal, G., & Canbeyli, R. S. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112047 · Cited by 113

Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine

Kokkinou, M., Irvine, E. E., Bonsall, D. R., Natesan, S., Wells, L. A., Smith, M., Glegola, J. A., Paul, E. J., Tossell, K., Veronese, M., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0740-6 · Cited by 107

Frontal white matter integrity is related to psychomotor retardation in major depression

Walther, S., Hügli, S., Höfle, O., Federspiel, A., Horn, H., Bracht, T., Wiest, R., Strik, W. K., & Müller, T. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.03.019 · Cited by 102

Triple reuptake inhibitors for treating subtypes of major depressive disorder: the monoamine hypothesis revisited

Prins, J., Olivier, B., & Korte, S. M. (2011) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2011.594039 · Cited by 106

The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression

Roiser, J. P., McLean, A., Ogilvie, A. D., Blackwell, A. D., Bamber, D. J., Goodyer, I., Jones, P. B., & Sahakian, B. J. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300659 · Cited by 96

Asymmetrical frontal cortical activity associated with differential risk for mood and anxiety disorder symptoms: An RDoC perspective

Nusslock, R., Walden, K., & Harmon-Jones, E. (2015) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2015.06.004 · Cited by 95

Focal and lateralized subcortical abnormalities in unipolar major depressive disorder: an automated multivoxel proton magnetic resonance spectroscopy study

Vythilingam, M., Charles, H. C., Tupler, L. A., Blitchington, T. F., Kelley, L., & Krishnan, K. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01908-x · Cited by 94

Neurocognitive predictors of antidepressant clinical response

Bruder, G. E., Alvarenga, J. E., Alschuler, D., Abraham, K., Keilp, J. G., Hellerstein, D. J., Stewart, J. W., & McGrath, P. J. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.04.057 · Cited by 89

Cortico-Cortical White Matter Motor Pathway Microstructure Is Related to Psychomotor Retardation in Major Depressive Disorder

Bracht, T., Federspiel, A., Schnell, S., Horn, H., Höfle, O., Wiest, R., Dierks, T., Strik, W. K., Müller, T., & Walther, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052238 · Cited by 90

Differential patterns of psychomotor functioning in unmedicated melancholic and nonmelancholic depressed patients

Pier, M. P. B. I., Hulstijn, W., & Sabbe, B. (2004) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2003.11.008 · Cited by 89

Subjective Effects of AMPT-induced Dopamine Depletion in Schizophrenia Correlation between Dysphoric Responses and Striatal D2 Binding Ratios on SPECT Imaging

Voruganti, L. N. P. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00263-9 · Cited by 88

Does dopamine dysfunction drive depression?

Malhi, G. S., & Berk, M. (2007) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2007.00969.x · Cited by 86

DRD2/ANKK1 Taq1A polymorphism (rs1800497) has opposing effects on D2/3 receptor binding in healthy controls and patients with major depressive disorder

Savitz, J. B., Hodgkinson, C. A., Martin-Söelch, C., Shen, P., Szczepanik, J. E., Nugent, A. C., Herscovitch, P., Grace, A. A., Goldman, D. A., & Drevets, W. C. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114571300045x · Cited by 81

A Critique of the Dopamine Hypothesis of Schizophrenia and Psychosis

Moncrieff, J. (2009) · Harvard Review of Psychiatry · doi:10.1080/10673220902979896 · Cited by 83

Frontal-subcortical circuits

Lichter, D. G. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139016919.007 · Cited by 77

Imaging the pathophysiology of major depressive disorder - from localist models to circuit-based analysis

Treadway, M. T., & Pizzagalli, D. A. (2014) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-4-5 · Cited by 79

Brain structures implicated in inflammation-associated depression

Harrison, N. A. (2016) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2016_30 · Cited by 74

Imaging studies on dopamine transporter and depression: A review of literature and suggestions for future research

Camardese, G., Giuda, D. D., Nicola, M. D., Cocciolillo, F., Giordano, A., Janiri, L., & Guglielmo, R. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.12.006 · Cited by 72

Neural correlates of disbalanced motor control in major depression

Walther, S., Höfle, O., Federspiel, A., Horn, H., Hügli, S., Wiest, R., Strik, W. K., & Müller, T. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.08.020 · Cited by 73

Striatal dopamine D2 receptors in medication-naive patients with major depressive disorder as assessed with [11C]raclopride PET

Hirvonen, J., Karlsson, H., Kajander, J., Markkula, J., Rasi-Hakala, H., Någren, K., Salminen, J. K., & Hietala, J. A. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1088-9 · Cited by 69

Striatal dopaminergic activity (FDOPA‐PET) associated with cognitive items of a depression scale (MADRS) in Parkinson's disease

Koerts, J., Leenders, K. L., Koning, M. D., Portman, A. T., & van Beilen, M. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05580.x · Cited by 70

Subjective Experience and Dopamine D 2 Receptor Occupancy in Patients Treated with Antipsychotics: Clinical Implications

de Haan, L., Lavalaye, J., van Bruggen, M., van Nimwegen, L. J. M., Booij, J., van Amelsvoort, T., & LINSZEN, D. H. (2004) · The Canadian Journal of Psychiatry · doi:10.1177/070674370404900503 · Cited by 69

Classification of schizophrenic patients and healthy controls using [18F] fluorodopa PET imaging

BOSE, S., Turkheimer, F., Howes, O. D., Mehta, M. A., CUNLIFFE, R., Stokes, P. R. A., & Grasby, P. M. (2008) · Schizophrenia Research · doi:10.1016/j.schres.2008.09.011 · Cited by 67

The Neurobiology of Motivational Deficits in Depression—An Update on Candidate Pathomechanisms

Treadway, M. T. (2015) · Current topics in behavioral neurosciences · doi:10.1007/7854_2015_400 · Cited by 65

Longitudinal changes of day-time and night-time gross motor activity in clinical responders and non-responders of major depression

Todder, D., Caliskan, S., & Baune, B. T. (2009) · The World Journal of Biological Psychiatry · doi:10.3109/15622970701403081 · Cited by 63

Reduced striatal dopamine transmission in REM sleep behavior disorder comorbid with depression

Wing, Y. K., Lam, S. P., Zhang, J., Leung, E. Y. L., Ho, C. L., Chen, S., Cheung, M.-K., Li, S. X., Chan, J. W. Y., Mok, V., et al. (2015) · Neurology · doi:10.1212/wnl.0000000000001215 · Cited by 62

A Preliminary Study of DBH (Encoding Dopamine Beta-Hydroxylase) Genetic Variation and Neural Correlates of Emotional and Motivational Processing in Individuals With and Without Pathological Gambling

Yang, B., Balodis, I. M., Lacadie, C., Xu, J., & Potenza, M. N. (2016) · Journal of Behavioral Addictions · doi:10.1556/2006.5.2016.026 · Cited by 59

Decreased cerebral blood flow in the primary motor cortex in major depressive disorder with psychomotor retardation

Yin, Y., Wang, M., Wang, Z., Xie, C., Zhang, H., Zhang, H., Zhang, Z., & Yuan, Y. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.08.013 · Cited by 55

Dopaminergic dysfunction and psychiatric symptoms in movement disorders: a 123I-FP-CIT SPECT study

Giuda, D. D., Camardese, G., Bentivoglio, A. R., Cocciolillo, F., Guidubaldi, A., Pucci, L., Bruno, I., Janiri, L., Giordano, A., & Fasano, A. A. (2012) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-012-2232-7 · Cited by 58

Dopamine in major depressive disorder: A systematic review and meta-analysis of in vivo imaging studies

Mizuno, Y., Ashok, A. H., Bhat, B. B., Jauhar, S., & Howes, O. D. (2023) · Journal of Psychopharmacology · doi:10.1177/02698811231200881 · Cited by 63

S32504, a Novel Naphtoxazine Agonist at Dopamine D3/D2 Receptors: III. Actions in Models of Potential Antidepressive and Anxiolytic Activity in Comparison with Ropinirole

Millan, M. J., Brocco, M., Papp, M., Serres, F., Rochelle, C. D. L., Sharp, T., Péglion, J.-L., & Dekeyne, A. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.062463 · Cited by 53

The many different faces of major depression: It is time for personalized medicine

Korte, S. M., Prins, J., Krajnc, A. M., Hendriksen, H., Oosting, R. S., Westphal, K. G. C., Korte-Bouws, G. A. H., & Olivier, B. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.11.045 · Cited by 54

Neuropathological changes in the substantia nigra in schizophrenia but not depression

Williams, M. R., Galvin, K., OSullivan, B., Macdonald, C., Ching, E. W.-K., Turkheimer, F., Howes, O. D., Pearce, R. K. B., Hirsch, S. R., & Maier, M. (2013) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-013-0479-z · Cited by 52

Reduced dorsal striatal gray matter volume predicts implicit suicidal ideation in adolescents

Ho, T. C., Cichocki, A. C., Gifuni, A. J., Catalina Camacho, M., Ordaz, S. J., Singh, M. K., & Gotlib, I. H. (2018) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsy089 · Cited by 48

Protective effects of pseudoginsenoside-F11 on methamphetamine-induced neurotoxicity in mice

Wu, C. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(03)00215-6 · Cited by 47

Antidepressant-like properties of the anti-Parkinson agent, piribedil, in rodents: mediation by dopamine D2 receptors

Brocco, M., Dekeyne, A., Papp, M., & Millan, M. J. (2006) · Behavioural Pharmacology · doi:10.1097/01.fbp.0000236267.41806.5b · Cited by 49

Dopaminergic function in depressed patients with affective flattening or with impulsivity: [18F]Fluoro-l-dopa positron emission tomography study with voxel-based analysis

Bragulat, V., Martinot, M. P., Artiges, É., Frouin, V., Poline, J., & Martinot, J. (2007) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2006.07.002 · Cited by 49

An open pilot study of nefazodone in depression with anger attacks: relationship between clinical response and receptor binding

Mischoulon, D., Dougherty, D. D., Bottonari, K. A., Gresham, R. L., Sonawalla, S. B., Fischman, A. J., & D, M. F. M. (2002) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(02)00082-3 · Cited by 45

Intravenous self‐administration of amphetamine is increased in a rat model of depression

Holmes, P. V., Masini, C. V., Primeaux, S. D., Garrett, J. L., Zellner, A. S., Stogner, K. A., Duncan, A. A., & Crystal, J. D. (2002) · Synapse · doi:10.1002/syn.10105 · Cited by 43

Characterizing major depression phenotypes by presence and type of psychomotor disturbance in adolescents and young adults

Leventhal, A. M., Pettit, J. W., & Lewinsohn, P. M. (2007) · Depression and Anxiety · doi:10.1002/da.20328 · Cited by 38

Investigation of associations between recurrence of major depressive disorder and spinal posture alignment: A quantitative cross-sectional study

Canales, J. Z., Fiquer, J. T., Campos, R. N., Soeiro‐de‐Souza, M. G., & Moreno, R. A. (2016) · Gait & Posture · doi:10.1016/j.gaitpost.2016.12.011 · Cited by 42

Antidepressant drug development: Focus on triple monoamine reuptake inhibition

Lane, R. M. (2014) · Journal of Psychopharmacology · doi:10.1177/0269881114553252 · Cited by 41

No psychomotor slowing in fine motor tasks in dysthymia

Pier, M. P. B. I., Hulstijn, W., & Sabbe, B. G. C. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2004.05.002 · Cited by 38

Brick by Brick: Building a Transdiagnostic Understanding of Inflammation in Psychiatry

Thylur, D. S., & Goldsmith, D. R. (2022) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000326 · Cited by 42

Neurocognitive Predictors of Response in Treatment Resistant Depression to Subcallosal Cingulate Gyrus Deep Brain Stimulation

McInerney, S. J., McNeely, H. E., Geraci, J., Giacobbe, P., Rizvi, S. J., Ceniti, A. K., Cyriac, A., Mayberg, H. S., Lozano, A. M., & Kennedy, S. H. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00074 · Cited by 37

Psychomotor Changes in Major Depressive Disorder during Sertraline Treatment

Schrijvers, D., Maas, Y. J., Pier, M. P. B. I., Madani, Y., Hulstijn, W., & Sabbe, B. G. C. (2009) · Neuropsychobiology · doi:10.1159/000205516 · Cited by 36

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Froudist‐Walsh, S., Bloomfield, M., Veronese, M., Kroll, J., Karolis, V. R., Jauhar, S., Bonoldi, I., McGuire, P. K., Kapur, S., Murray, R. M., et al. (2017) · eLife · doi:10.7554/elife.29088 · Cited by 36

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Linden, S. C., Jackson, M. C., Subramanian, L., Healy, D., & Linden, D. E. J. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.08.002 · Cited by 36

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Hsiao, M., Lin, K., Liu, C.-Y., & Schatz, D. B. (2012) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2012.06.004 · Cited by 30

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Sheikh, H. I., Kryski, K. R., Smith, H. J., Dougherty, L. R., Klein, D. N., Bufferd, S. J., Singh, S. M., & Hayden, E. P. (2013) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32141 · Cited by 31

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Damme, K. S. F., Park, J. S., Walther, S., Vargas, T., Shankman, S. A., & Mittal, V. A. (2021) · Schizophrenia Bulletin · doi:10.1093/schbul/sbab133 · Cited by 29

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Newberg, A. B., Moss, A., Monti, D., & Alavi, A. A. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06162.x · Cited by 29

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Koerts, J., Leenders, K. L., Koning, M. D., Bouma, A., & van Beilen, M. (2008) · European Journal of Neurology · doi:10.1111/j.1468-1331.2008.02101.x · Cited by 26

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Bragulat, V., Martinot, M. P., Dollé, F., Jouvent, R., & Martinot, J. (2000) · NeuroImage · doi:10.1016/s1053-8119(00)91137-6