The Critical Relationship Between Anxiety and Depression

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States: Results From the National Comorbidity Survey

Kessler, R. C. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010008002 · Cited by 12,370 · see citing works

Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication

Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052 · see citing works

Posttraumatic Stress Disorder in the National Comorbidity Survey

Kessler, R. C. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950240066012 · Cited by 10,379 · see citing works

Lifetime prevalence of mental disorders in U.S. adolescents: results from the National Comorbidity Survey Replication - Adolescent Supplement (NCS-A)

Merikangas, K. R., He, J.-P., Burstein, M., Swanson, S. A., Avenevoli, S., Cui, L., Benjet, C., Georgiades, K., & Swendsen, J. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.05.017 · Cited by 6,278 · see citing works

Anxiety and Anxiety Disorders in Children and Adolescents: Developmental Issues and Implications for DSM-V

Beesdo, K., Knappe, S., & Pine, D. S. (2009) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2009.06.002 · Cited by 1,703 · see citing works

Identification of a Common Neurobiological Substrate for Mental Illness

Goodkind, M., Eickhoff, S. B., Oathes, D. J., Jiang, Y., Chang, A., Jones-Hagata, L. B., Ortega, B. N., Zaiko, Y. V., Roach, E. L., Korgaonkar, M. S., et al. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.2206 · Cited by 1,404 · see citing works

Difference in treatment outcome in outpatients with anxious versus nonanxious depression: A STAR*D report

Fava, M., Rush, A. J., Alpert, J. E., Balasubramani, G. K., Wisniewski, S. R., Carmin, C. N., Biggs, M. M., Zisook, S., Leuchter, A., Howland, R., et al. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111868 · Cited by 927 · see citing works

All for One and One for All: Mental Disorders in One Dimension

Caspi, A., & Moffitt, T. E. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2018.17121383 · Cited by 918 · see citing works

The Descriptive Epidemiology of Commonly Occurring Mental Disorders in the United States

Kessler, R. C., & Wang, P. S. (2008) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.29.020907.090847 · Cited by 888 · see citing works

Psychedelics and Psychedelic-Assisted Psychotherapy

Reiff, C. M., Richman, E. E., Nemeroff, C. B., Carpenter, L. L., Widge, A. S., Rodriguez, C. I., Kalin, N. H., McDonald, W. M., & and the Work Group on Biomarkers and Novel Treatments, A. D. O. T. A. P. A. C. O. R. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19010035 · Cited by 649 · see citing works

Anxious and non-anxious major depressive disorder in the World Health Organization World Mental Health Surveys

Kessler, R. C., Sampson, N. A., Berglund, P., Gruber, M. J., Al-Hamzawi, A., Andrade, L., Bunting, B., Demyttenaere, K., Florescu, S., de Girolamo, G., et al. (2015) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796015000189 · Cited by 636 · see citing works

Identification of Common Neural Circuit Disruptions in Cognitive Control Across Psychiatric Disorders

McTeague, L. M., Huemer, J., Carreon, D. M., Jiang, Y., Eickhoff, S. B., & Etkin, A. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.16040400 · Cited by 635 · cited 1× · see citing works

A Population-Based Twin Study of the Relationship Between Neuroticism and Internalizing Disorders

Hettema, J. M., Neale, M. C., Myers, J., Prescott, C. A., & Kendler, K. S. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.5.857 · Cited by 633 · see citing works

Behavioral Inhibition and Risk for Developing Social Anxiety Disorder: A Meta-Analytic Study

Clauss, J. A., & Blackford, J. U. (2012) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2012.08.002 · Cited by 573 · see citing works

Multimodal Abnormalities of Brain Structure and Function in Major Depressive Disorder: A Meta-Analysis of Neuroimaging Studies

Gray, J. P., Müller, V. I., Eickhoff, S. B., & Fox, P. T. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19050560 · Cited by 449 · see citing works

Clinical correlates and symptom patterns of anxious depression among patients with major depressive disorder in STAR*D

FAVA, M., ALPERT, J. E., CARMIN, C. N., WISNIEWSKI, S. R., TRIVEDI, M. H., BIGGS, M. M., SHORES-WILSON, K., MORGAN, D., SCHWARTZ, T., BALASUBRAMANI, G. K., et al. (2004) · Psychological Medicine · doi:10.1017/s0033291704002612 · Cited by 406 · see citing works

Identification of common neural circuit disruptions in emotional processing across psychiatric disorders

McTeague, L. M., Rosenberg, B. M., Lopez, J. W., Carreon, D. M., Huemer, J., Jiang, Y., Chick, C. F., Eickhoff, S. B., & Etkin, A. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.18111271 · Cited by 388 · see citing works

Distinct symptom-specific treatment targets for circuit-based neuromodulation

Siddiqi, S. H., Taylor, S. F., Cooke, D., Pascual-Leone, A., George, M. S., & Fox, M. D. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19090915 · Cited by 375 · see citing works

Common abnormalities and disorder-specific compensation during implicit regulation of emotional processing in generalized anxiety and major depressive disorders

Etkin, A., & Schatzberg, A. F. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10091290 · Cited by 311 · see citing works

Social phobia and depression: Prevalence and comorbidity

Ohayon, M. M., & Schatzberg, A. F. (2010) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2009.07.018 · Cited by 305 · see citing works

What is the genetic relationship between anxiety and depression?

Hettema, J. M. (2008) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.30171 · Cited by 207 · see citing works

Psychiatric comorbidity in patients with generalized anxiety disorder

Brawman‐Mintzer, O., Lydiard, R. B., Emmanuel, N. P., Payeur, R., Johnson, M. J., Roberts, J., Jarrell, M. P., & Ballenger, J. C. (1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.8.1216 · Cited by 201 · see citing works

Toward Circuit Mechanisms of Pathophysiology in Depression

Spellman, T., & Liston, C. M. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20030280 · Cited by 169 · see citing works

Clinical characteristics and treatment outcomes of patients with major depressive disorder and comorbid anxiety disorders: results from a European multicenter study

Dold, M., Bartova, L., Souery, D., Mendlewicz, J., Serretti, A., Porcelli, S., Zohar, J., Montgomery, S., & Kasper, S. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.02.020 · Cited by 131 · see citing works

Cortico-Limbic Interactions Mediate Adaptive and Maladaptive Responses Relevant to Psychopathology

Kovner, R., Oler, J. A., & Kalin, N. H. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19101064 · Cited by 103 · see citing works

Age Differences in the Neural Correlates of Anxiety Disorders: An fMRI Study of Response to Learned Threat

Gold, A. L., Abend, R., Britton, J. C., Behrens, B., Farber, M. J., Ronkin, E. G., Chen, G., Leibenluft, E., & Pine, D. S. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19060650 · Cited by 80 · see citing works

Management of anxiety disorders: The added challenge of comorbidity

Dunner, D. L. (2001) · Depression and Anxiety · doi:10.1002/da.1018 · Cited by 51 · see citing works

What Does It Mean to Be Transdiagnostic and How Would We Know?

Barch, D. M. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20030243 · Cited by 41 · see citing works

The Rearing Environment and Risk for Major Depression: A Swedish National High-Risk Home-Reared and Adopted-Away Co-Sibling Control Study

Kendler, K. S., Ohlsson, H., Sundquist, J., & Sundquist, K. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19090911 · Cited by 36 · see citing works

Some Comments on Psychedelic Research

Schatzberg, A. F. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20030272 · Cited by 19 · see citing works

Mapping Symptom Clusters to Circuits: Toward Personalizing TMS Targets to Improve Treatment Outcomes in Depression

Nestor, S. M., & Blumberger, D. M. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20030271 · Cited by 13 · see citing works

Is Depression Nature or Nurture? Yes

Weissman, M. M. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20020186 · Cited by 7 · see citing works

Developmental Differences in Neural Responding to Threat and Safety: Implications for Treating Youths With Anxiety

Gee, D. G., & Kribakaran, S. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20020225 · Cited by 7 · see citing works

Anxiety Disorders: A Review

Szuhany, K. L., & Simon, N. M. (2022) · JAMA · doi:10.1001/jama.2022.22744 · Cited by 541 · see citing works

Impact on mental health due to covid-19 pandemic: Cross-sectional study in Portugal and Brazil.

Passos, L., Prazeres, F., Teixeira, A., & Martins, C. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186794 · Cited by 154 · see citing works

A randomized controlled trial of a smartphone-based well-being training in public school system employees during the COVID-19 pandemic

Hirshberg, M. J., Frye, C., Dahl, C. J., Riordan, K. M., Vack, N. J., Sachs, J., Goldman, R., Davidson, R. J., & Goldberg, S. B. (2022) · Journal of Educational Psychology · doi:10.1037/edu0000739 · Cited by 78 · see citing works

Music's dual role in emotion regulation: network analysis of music use, emotion regulation self-efficacy, alexithymia, anxiety, and depression

Tan, M., Zhou, X., Shen, L., Li, Y., & Chen, X. (2024) · Depression and Anxiety · doi:10.1155/2024/1790168 · Cited by 25 · see citing works

Challenges in Recruiting University Students for Web-Based Indicated Prevention of Depression and Anxiety: Results From a Randomized Controlled Trial (ICare Prevent)

Bolinski, F., Kleiboer, A., Neijenhuijs, K., Karyotaki, E., Wiers, R., de Koning, L., Jacobi, C., Zarski, A.-C., Weisel, K. K., Cuijpers, P., et al. (2022) · Journal of Medical Internet Research · doi:10.2196/40892 · Cited by 24 · see citing works

Attenuated interoceptive processing in individuals with major depressive disorder and high repetitive negative thinking

Park, H., Sanchez, S. M., Kuplicki, R., Tsuchiyagaito, A., Khalsa, S. S., Paulus, M. P., & Guinjoan, S. M. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.10.020 · Cited by 20 · see citing works

Feasibility and Preliminary Efficacy of Web-Based and Mobile Interventions for Common Mental Health Problems in Working Adults: Multi-Arm Randomized Pilot Trial

Economides, M., Bolton, H., Male, R., & Cavanagh, K. (2022) · JMIR Formative Research · doi:10.2196/34032 · Cited by 21 · see citing works

“Close your eyes and relax”: the role of hypnosis in reducing anxiety, and its implications for the prevention of cardiovascular diseases

Leo, D. G., Keller, S. S., & Proietti, R. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1411835 · Cited by 21 · see citing works

The prospective association of adolescent loneliness and low resilience with anxiety and depression in young adulthood: The HUNT study

Parlikar, N., Strand, L. B., Kvaløy, K., Espnes, G. A., & Moksnes, U. K. (2025) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-025-02888-2 · Cited by 7 · see citing works

Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study

Nan, J., Purpura, S., Jaiswal, S., Afshar, H., Maric, V., Manchanda, J. K., Taylor, C. T., Ramanathan, D., & Mishra, J. (2026) · NPP—Digital Psychiatry and Neuroscience · doi:10.1038/s44277-026-00062-3 · Cited by 1 · see citing works

Neural correlates of altered interoception in depressive and anxiety disorders: a systematic review and meta-analysis

Bednarek, L., Harrison, B. J., Davey, C. G., Steward, T., & Jamieson, A. J. (2026) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-026-02201-5 · Cited by 1 · see citing works

Should excessive worry be required for a diagnosis of generalized anxiety disorder? Results from the US National Comorbidity Survey Replication

Ruscio, A. M., Lane, M. C., Roy‐Byrne, P., Stang, P., Stein, D. J., Wïttchen, H., & Kessler, R. C. (2005) · Psychological Medicine · doi:10.1017/s0033291705005908 · Cited by 147 · see citing works

Functional impairment related to painful physical symptoms in patients with generalized anxiety disorder with or without comorbid major depressive disorder: post hoc analysis of a cross-sectional study

Romera, I., Montejo, A. L., Caballero, F., Caballero, L., Arbesú, J. Á., Polavieja, P., Desaiah, D., & Gilaberte, I. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-69 · Cited by 17 · see citing works

412. Impaired Eating Behaviors but Intact Metabolic Hormone Levels in Individuals With Major Depressive Disorder and Generalized Anxiety Disorder From the T1000 Cohort

McNaughton, B., Burrows, K., Choquette, E. M., et al. (2023) · Biological Psychiatry · doi:10.1016/j.biopsych.2023.02.652

Broadening the definition of generalized anxiety disorder: Effects on prevalence and associations with other disorders in the National Comorbidity Survey Replication

Ruscio, A. M., Chiu, W. T., Roy-Byrne, P., Stang, P. E., Stein, D. J., Wittchen, H.-U., & Kessler, R. C. (2007) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2006.10.004 · Cited by 145 · see citing works

DSM-III-R Generalized Anxiety Disorder in the National Comorbidity Survey

Wittchen, H.-U. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950050015002 · Cited by 967 · see citing works