The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Neurobiology of fear responses: the role of the amygdala
Abstract
Evidence from many different laboratories using a variety of experimental techniques and animal species indicates that the amygdala plays a crucial role in conditioned fear and anxiety, as well as attention. Many amygdaloid projection areas are critically involved in specific signs used to measure fear and anxiety. Electrical stimulation of the amygdala elicits a pattern of behaviors that mimic natural or conditioned fear. Lesions of the amygdala block innate or conditioned fear, as well as various measures of attention, and local infusions of drugs into the amygdala have anxiolytic effects in several behavioral tests. N-methyl-D-aspartate (NMDA) receptors in the amygdala may be important in the acquisition of conditioned fear, whereas non-NMDA receptors are important for the expression of conditioned fear. The peptide corticotropin-releasing hormone appears to be especially important in fear or anxiety and may act within the amygdala to orchestrate parts of the fear reaction.
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Cites
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.
Phillips, R. G., & LeDoux, J. E. (1992) · Behavioral Neuroscience · doi:10.1037/0735-7044.106.2.274 · Cited by 3,292
Modality-Specific Retrograde Amnesia of Fear
Kim, J. J., & Fanselow, M. S. (1992) · Science · doi:10.1126/science.1585183 · Cited by 2,483
Adolphs, R., Tranel, D., Damasio, H., & Damasio, A. (1994) · Nature · doi:10.1038/372669a0 · Cited by 2,360
The role of the amygdala in fear and anxiety
Davis, M. (1992) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.15.030192.002033 · Cited by 2,357
Self-citationBechara, A., Tranel, D., Damasio, H., Adolphs, R., Rockland, C., & Damasio, A. R. (1995) · Science · doi:10.1126/science.7652558 · Cited by 1,400
Krettek, J. E., & Price, J. L. (1978) · Journal of Comparative Neurology · doi:10.1002/cne.901780204 · Cited by 1,293
Extinction of emotional learning: contribution of medial prefrontal cortex
Morgan, M. A., Romanski, L. M., & LeDoux, J. E. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90241-c · Cited by 897
Miserendino, M. J. D., Sananes, C. B., Melia, K. R., & Davis, M. (1990) · Nature · doi:10.1038/345716a0 · Cited by 824
Self-citationOrganization of endogenous opiate and nonopiate pain control systems
Watkins, L. R., & Mayer, D. J. (1982) · Science · doi:10.1126/science.6281891 · Cited by 791
Morgan, M. A., & LeDoux, J. E. (1995) · Behavioral Neuroscience · doi:10.1037/0735-7044.109.4.681 · Cited by 717
Kim, J. J., Rison, R. A., & Fanselow, M. S. (1993) · Behavioral Neuroscience · doi:10.1037/0735-7044.107.6.1093 · Cited by 615
Amygdala central nucleus lesions: Effect on heart rate conditioning in the rabbit
Kapp, B. S., Frysinger, R. C., Gallagher, M., & Haselton, J. R. (1979) · Physiology & Behavior · doi:10.1016/0031-9384(79)90304-4 · Cited by 590
Pich, E., Lorang, M., Yeganeh, M., Rodriguez de Fonseca, F., Raber, J., Koob, G., & Weiss, F. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-08-05439.1995 · Cited by 565
Rassnick, S., Heinrichs, S. C., Britton, K. T., & Koob, G. F. (1993) · Brain Research · doi:10.1016/0006-8993(93)91352-s · Cited by 407
Goldstein, L. E., Rasmusson, A. M., Bunney, B. S., & Roth, R. H. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-15-04787.1996 · Cited by 387
Hitchcock, J. M., & Davis, M. (1991) · Behavioral Neuroscience · doi:10.1037/0735-7044.105.6.826 · Cited by 345
Self-citationRole of the amygdala and periaqueductal gray in anxiety and panic.
Graeff, F. G., Silveira, M. C. L., Nogueira, R. L., Audi, E. A., & Oliveira, R. M. W. (1993) · Behavioural Brain Research · doi:10.1016/0166-4328(93)90097-a · Cited by 301
Iwata, J., Chida, K., & LeDoux, J. E. (1987) · Brain Research · doi:10.1016/0006-8993(87)90978-4 · Cited by 272
Zola‐Morgan, S., Squire, L. R., Clower, R. P., & Alvarez‐Royo, P. (1991) · Hippocampus · doi:10.1002/hipo.450010208 · Cited by 265
Sarnyai, Z., Bíró, É., Gardi, J., Vecsernyés, M., Julesz, J., & Telegdy, G. (1995) · Brain Research · doi:10.1016/0006-8993(95)00043-p · Cited by 255
Mesencephalic central gray lesions and fear-motivated behavior in rats
Liebman, J. M., Mayer, D. J., & Liebeskind, J. C. (1970) · Brain Research · doi:10.1016/0006-8993(70)90062-4 · Cited by 241
Correlation between the Pharmacology of Long-Term Potentiation and the Pharmacology of Memory
Izquierdo, I., & Medina, J. H. (1995) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1995.1002 · Cited by 230
Liebsch, G., Landgraf, R., Gerstberger, R., Probst, J. C., Wotjak, C. T., Engelmann, M., Holsboer, F., & Montkowski, A. (1995) · Regulatory Peptides · doi:10.1016/0167-0115(95)00099-w · Cited by 220
Kim, M., & Davis, M. (1993) · Behavioral Neuroscience · doi:10.1037/0735-7044.107.4.580 · Cited by 139
Self-citationUncus and Amygdala Lesions: Effects on Social Behavior in the Free-Ranging Rhesus Monkey
Dicks, D., Myers, R. E., & Kling, A. (1969) · Science · doi:10.1126/science.165.3888.69 · Cited by 132
Effects of lesions of the central nucleus of the amygdala on anxiety-like behaviors in the rat
Kopchia, K. L., Altman, H. J., & Commissaris, R. L. (1992) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(92)90176-g · Cited by 119
Involvement of the amygdaloid complex in neuromodulatory influences on memory storage
McGaugh, J. L., Introini-Collison, I. B., Nagahara, A. H., Cahill, L., Brioni, J. D., & Castellano, C. (1990) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80065-x · Cited by 117
Noninteractive effects of diazepam and amygdaloid lesions in two animal models of anxiety.
Treit, D., Pesold, C., & Rotzinger, S. (1993) · Behavioral Neuroscience · doi:10.1037/0735-7044.107.6.1099 · Cited by 78
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Drug Addiction, Dysregulation of Reward, and Allostasis
Koob, G. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00195-0 · Cited by 2,953
The amygdala: vigilance and emotion
Davis, M., & Whalen, P. J. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000812 · Cited by 2,882
Self-citationFear memories require protein synthesis in the amygdala for reconsolidation after retrieval
Nader, K., Schafe, G. E., & Le Doux, J. E. (2000) · Nature · doi:10.1038/35021052 · Cited by 2,706
Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex
Cardinal, R. N., Parkinson, J. A., Hall, J., & Everitt, B. J. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(02)00007-6 · Cited by 2,129
Dysfunction in the neural circuitry of emotion regulation–a possible prelude to violence
Davidson, R. J., Putnam, K. M., & Larson, C. L. (2000) · Science · doi:10.1126/science.289.5479.591 · Cited by 1,894
Metadata
- Venue
- The Journal of Neuropsychiatry and Clinical Neurosciences
- Published
- 1997-08-01
- Volume
- 9
- Issue
- 3
- Pages
- 382-402
- ISSN
- 0895-0172 (ISSN-L)
- 1545-7222
- OpenAlex
- W141581154
- Cited by
- 561
- References
- 28
- FWCI
- 11.17
- Type
- journal article
- Language
- en
- Open access
- closed
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