Differing associations between Aβ accumulation, hypoperfusion, blood–brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

Montine, T. J., Phelps, C. H., Beach, T. G., Bigio, E. H., Cairns, N. J., Dickson, D. W., Duyckaerts, C., Frosch, M. P., Masliah, E., Mirra, S. S., et al. (2012) · Acta Neuropathologica · doi:10.1007/s00401-011-0910-3 · Cited by 2,992 · cited 1× · see citing works

Blood-brain barrier breakdown in the aging human hippocampus

Montagne, A., Barnes, S. R., Sweeney, M. D., Halliday, M. R., Sagare, A. P., Zhao, Z., Toga, A. W., Jacobs, R. E., Liu, C. Y., Amezcua, L., et al. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.032 · Cited by 2,102 · see citing works

The role of pericytes in blood-vessel formation and maintenance

Bergers, G., & Song, S. (2005) · Neuro-Oncology · doi:10.1215/s1152851705000232 · Cited by 1,584 · see citing works

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

Bell, R. D., Winkler, E. A., Sagare, A. P., Singh, I., LaRue, B., Deane, R., & Zlokovic, B. V. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.043 · Cited by 1,448 · see citing works

Cerebral microvascular pathology in aging and Alzheimer's disease

Farkas, E., & Luiten, P. G. M. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00068-x · Cited by 1,102 · see citing works

Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam Study

Ruitenberg, A., den Heijer, T., Bakker, S. L. M., van Swieten, J. C., Koudstaal, P. J., Hofman, A., & Breteler, M. M. B. (2005) · Annals of Neurology · doi:10.1002/ana.20493 · Cited by 733 · see citing works

Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

Halliday, M. R., Rege, S. V., Ma, Q., Zhao, Z., Miller, C. A., Winkler, E. A., & Zlokovic, B. V. (2016) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2015.44 · Cited by 649 · see citing works

A role for VEGF as a negative regulator of pericyte function and vessel maturation

Greenberg, J. I., Shields, D. J., Barillas, S. G., Acevedo, L. M., Murphy, E. A., Huang, J., Scheppke, L., Stockmann, C., Johnson, R. S., Angle, N., et al. (2008) · Nature · doi:10.1038/nature07424 · Cited by 630 · see citing works

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

van de Haar, H. J., Burgmans, S., Jansen, J. F. A., van Osch, M. J. P., van Buchem, M. A., Muller, M., Hofman, P. A. M., Verhey, F. R. J., & Backes, W. H. (2016) · Radiology · doi:10.1148/radiol.2016152244 · Cited by 601 · see citing works

Deficiency in Mural Vascular Cells Coincides with Blood–Brain Barrier Disruption in <scp>A</scp> lzheimer's Disease

Sengillo, J. D., Winkler, E. A., Walker, C. T., Sullivan, J. S., Johnson, M., & Zlokovic, B. V. (2013) · Brain Pathology · doi:10.1111/bpa.12004 · Cited by 553 · see citing works

Microvascular injury and blood–brain barrier leakage in Alzheimer's disease

Zipser, B. D., Johanson, C. E., Gonzalez, L., Berzin, T. M., Tavares, R., Hulette, C. M., Vitek, M. P., Hovanesian, V., & Stopa, E. G. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.05.016 · Cited by 487 · see citing works

Mild Cognitive Impairment and Alzheimer Disease: Patterns of Altered Cerebral Blood Flow at MR Imaging

Dai, W., López, O. L., Carmichael, O. T., Becker, J. T., Kuller, L. H., & Gach, H. M. (2009) · Radiology · doi:10.1148/radiol.2503080751 · Cited by 393 · see citing works

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

Benzinger, T. L. S., Blazey, T., Jack, C. R., Koeppe, R. A., Su, Y., Xiong, C., Raichle, M. E., Snyder, A. Z., Ances, B. M., Bateman, R. J., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1317918110 · Cited by 391 · see citing works

Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling

Winkler, E. A., Bell, R. D., & Zloković, B. V. (2010) · Molecular Neurodegeneration · doi:10.1186/1750-1326-5-32 · Cited by 346 · see citing works

Cerebrovascular disease in ageing and Alzheimer’s disease

Love, S., & Miners, J. S. (2016) · Acta Neuropathologica · doi:10.1007/s00401-015-1522-0 · Cited by 299 · see citing works

Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein

Niwa, K., Kazama, K., Younkin, L., Younkin, S. G., Carlson, G. A., & Iadecola, C. (2002) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00022.2002 · Cited by 286 · see citing works

Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease

Wu, Z., Guo, H., Chow, N., Sallstrom, J., Bell, R. D., Deane, R., Brooks, A. I., Kanagala, S., Rubio, A., Sagare, A., et al. (2005) · Nature Medicine · doi:10.1038/nm1287 · Cited by 280 · see citing works

Cerebral Blood Flow Measured with 3D Pseudocontinuous Arterial Spin-labeling MR Imaging in Alzheimer Disease and Mild Cognitive Impairment: A Marker for Disease Severity

Binnewijzend, M. A. A., Kuijer, J. P. A., Benedictus, M. R., van der Flier, W. M., Wink, A. M., Wattjes, M. P., van Berckel, B. N. M., Scheltens, P., & Barkhof, F. (2012) · Radiology · doi:10.1148/radiol.12120928 · Cited by 260 · see citing works

Cerebral blood flow and metabolic abnormalities in Alzheimer’s disease

Matsuda, H. (2001) · Annals of Nuclear Medicine · doi:10.1007/bf02988596 · Cited by 233 · see citing works

Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor protein

Niwa, K., Kazama, K., Younkin, S. G., Carlson, G. A., & Iadecola, C. (2002) · Neurobiology of Disease · doi:10.1006/nbdi.2001.0460 · Cited by 218 · see citing works

The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant

Olichney, J. M., Hansen, L. A., Galasko, D., Saitoh, T., Hofstetter, C. R., Katzman, R., & Thal, L. J. (1996) · Neurology · doi:10.1212/wnl.47.1.190 · Cited by 216 · see citing works

Neurovascular unit impairment in early Alzheimer's disease measured with magnetic resonance imaging

van de Haar, H. J., Jansen, J. F. A., van Osch, M. J. P., van Buchem, M. A., Muller, M., Wong, S. M., Hofman, P. A. M., Burgmans, S., Verhey, F. R. J., & Backes, W. H. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.06.006 · Cited by 207 · see citing works

Aβ-peptides enhance vasoconstriction in cerebral circulation

Niwa, K., Porter, V. A., Kazama, K., Cornfield, D., Carlson, G. A., & Iadecola, C. (2001) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2001.281.6.h2417 · Cited by 202 · see citing works

The <i>APOE</i> ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients

Hultman, K., Strickland, S., & Norris, E. H. (2013) · Journal of Cerebral Blood Flow &amp; Metabolism · doi:10.1038/jcbfm.2013.76 · Cited by 183 · see citing works

Multivariate and Univariate Analysis of Continuous Arterial Spin Labeling Perfusion MRI in Alzheimer's Disease

Asllani, I., Habeck, C., Scarmeas, N., Borogovac, A., Brown, T. R., & Stern, Y. (2008) · Journal of Cerebral Blood Flow &amp; Metabolism · doi:10.1038/sj.jcbfm.9600570 · Cited by 172 · see citing works

Co-accumulation of vascular endothelial growth factor with β-amyloid in the brain of patients with Alzheimer’s disease

Yang, S., Bae, D., Kang, H. J., Gwag, B. J., Gho, Y. S., & Chae, C. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(03)00111-8 · Cited by 170 · see citing works

Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration

Cortés‐Canteli, M., Mattei, L., Richards, A. T., Norris, E. H., & Strickland, S. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.10.030 · Cited by 169 · see citing works

The concept of sporadic cerebral small vessel disease: A road map on key definitions and current concepts

Charidimou, A., Pantoni, L., & Love, S. (2015) · International Journal of Stroke · doi:10.1177/1747493015607485 · Cited by 168 · see citing works

<i>APOE</i>ɛ4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of Aβ protein

Chalmers, K., Wilcock, G. K., & Love, S. (2003) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.2003.00457.x · Cited by 156 · see citing works

The vascular factor in Alzheimer's disease: A study in Golgi technique and electron microscopy

Baloyannis, S. J., & Baloyannis, I. S. (2012) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2012.07.010 · Cited by 150 · see citing works

Shedding of soluble platelet-derived growth factor receptor-β from human brain pericytes

Sagare, A. P., Sweeney, M. D., Makshanoff, J., & Zlokovic, B. V. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.09.025 · Cited by 142 · see citing works

Vascular risk factors and Alzheimer's disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? An evidence-based review

Chui, H. C., Zheng, L., Reed, B., Vinters, H. V., & Mack, W. J. (2011) · Alzheimer s Research & Therapy · doi:10.1186/alzrt98 · Cited by 141 · see citing works

Differences in cerebral metabolic impairment between early and late onset types of Alzheimer's disease

Sakamoto, S., Ishii, K., Sasaki, M., Hosaka, K., Mori, T., Matsui, M., Hirono, N., & Mori, E. (2002) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(02)00114-4 · Cited by 139 · see citing works

Controlled Modulation of BBB Permeability Using the Bradykinin Agonist, RMP-7

Bartus, R. T., Elliott, P. J., Dean, R. L., Hayward, N. J., Nagle, T. L., Huff, M. R., Snodgrass, P., & Blunt, D. G. (1996) · Experimental Neurology · doi:10.1006/exnr.1996.0175 · Cited by 132 · see citing works

Endothelin-1 is Elevated in Alzheimer's Disease and Upregulated by Amyloid-β

Palmer, J. C., Barker, R., Kehoe, P. G., & Love, S. (2012) · Journal of Alzheimer's Disease · doi:10.3233/jad-2012-111760 · Cited by 110 · see citing works

Pathophysiology of Hypoperfusion of the Precuneus in Early A lzheimer's Disease

Miners, J. S., Palmer, J. C., & Love, S. (2015) · Brain Pathology · doi:10.1111/bpa.12331 · Cited by 109 · see citing works

Pathophysiology of white matter perfusion in Alzheimer’s disease and vascular dementia

Barker, R. M., Ashby, E. L., Wellington, D., Barrow, V. M., Palmer, J. C., Kehoe, P. G., Esiri, M. M., & Love, S. (2014) · Brain · doi:10.1093/brain/awu040 · Cited by 107 · see citing works

Endothelin-Converting Enzyme-2 Is Increased in Alzheimer’s Disease and Up-Regulated by Aβ

Palmer, J. C., Baig, S., Kehoe, P. G., & Love, S. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.081054 · Cited by 100 · see citing works

Hypometabolism in Alzheimer-Affected Brain Regions in Cognitively Healthy Latino Individuals Carrying the Apolipoprotein E ε4 Allele

Langbaum, J. B. S., Chen, K., Caselli, R. J., Lee, W., Reschke, C., Bandy, D., Alexander, G. E., Burns, C. M., Kaszniak, A. W., Reeder, S. A., et al. (2010) · Archives of Neurology · doi:10.1001/archneurol.2010.30 · Cited by 100 · see citing works

Permeability of the blood brain barrier by the bradykinin agonist, RMP-7: Evidence for a sensitive, auto-regulated, receptor-mediated system

Bartus, R. T., Elliott, P. J., Hayward, N. J., Dean, R. L., McEwen, E. L., & Fisher, S. K. (1996) · Immunopharmacology · doi:10.1016/0162-3109(96)00070-7 · Cited by 100 · see citing works

Alzheimer’s β‐amyloid peptide blocks vascular endothelial growth factor mediated signaling via direct interaction with VEGFR‐2

Patel, N. S., Mathura, V. S., Bachmeier, C. J., Beaulieu‐Abdelahad, D., Laporte, V., Weeks, O. I., MULLAN, M. J., & Paris, D. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06426.x · Cited by 99 · see citing works

VEGF coordinates interaction of pericytes and endothelial cells during vasculogenesis and experimental angiogenesis

Hagedorn, M., Balke, M., Schmidt, A., Bloch, W., Kurz, H., Javerzat, S., Rousseau, B., Wilting, J., & Bikfalvi, A. (2004) · Developmental Dynamics · doi:10.1002/dvdy.20020 · Cited by 90 · see citing works

Pharmacological Modification of Bradykinin Induced Breakdown of the Blood-brain Barrier

Raymond, J. J., Robertson, D. M., & Dinsdale, H. B. (1986) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100036301 · Cited by 87 · see citing works

Cerebral Hypoperfusion and the Energy Deficit in Alzheimer's Disease

Love, S., & Miners, J. (2016) · Brain Pathology · doi:10.1111/bpa.12401 · Cited by 82 · see citing works

Clusterin levels are increased in A lzheimer's disease and influence the regional distribution of Aβ

Miners, J. S., Clarke, P., & Love, S. (2016) · Brain Pathology · doi:10.1111/bpa.12392 · Cited by 81 · see citing works

Assessing White Matter Ischemic Damage in Dementia Patients by Measurement of Myelin Proteins

Barker, R. M., Wellington, D., Esiri, M. M., & Love, S. (2013) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2013.46 · Cited by 79 · see citing works

Pericytes Contribute to the Disruption of the Cerebral Endothelial Barrier via Increasing VEGF Expression: Implications for Stroke

Bai, Y., Zhu, X., Chao, J., Zhang, Y., Cheng, Q., Li, P., Liu, D., Han, B., Zhao, L., Zhang, J., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124362 · Cited by 76 · see citing works

Correlation of 99mTc-DTPA SPECT of the blood-brain barrier with neurologic outcome after acute stroke.

Lorberboym, M., Lampl, Y., & Sadeh, M. (2003) · PubMed · Cited by 66 · see citing works

Amyloid‐β‐induced Degeneration of Human Brain Pericytes Is Dependent on the Apolipoprotein E Genotype

Verbeek, M. M., Nostrand, W. E. V., Otte‐Höller, I., Wesseling, P., & de Waal, R. M. W. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06368.x · Cited by 55 · see citing works

PDGF is associated with neuronal and glial alterations of Alzheimer's disease

Masliah, E. (1995) · Neurobiology of Aging · doi:10.1016/0197-4580(95)00050-o · Cited by 54 · see citing works

Immunolocalization of platelet‐derived growth factor receptor‐β ( PDGFR‐β ) and pericytes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ( CADASIL )

Craggs, L., Fenwick, R., Oakley, A. E., Ihara, M., & Kalaria, R. N. (2014) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12188 · Cited by 48 · see citing works

Aβ degradation or cerebral perfusion? Divergent effects of multifunctional enzymes

Miners, J., Palmer, J., Tayler, H., Palmer, L., Ashby, E. L., Kehoe, P., & Love, S. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00238 · Cited by 48 · see citing works

White Matter Hypoperfusion and Damage in Dementia: Post‐Mortem Assessment

Love, S., & Miners, J. (2015) · Brain Pathology · doi:10.1111/bpa.12223 · Cited by 43 · see citing works

Reduced Vascular Endothelial Growth Factor and Capillary Density in the Occipital Cortex in Dementia with L ewy Bodies

Miners, J. S., Moulding, H., de Silva, R., & Love, S. (2014) · Brain Pathology · doi:10.1111/bpa.12130 · Cited by 43 · see citing works

Assessment of activation of the plasma kallikrein-kinin system in frontal and temporal cortex in Alzheimer's disease and vascular dementia

Ashby, E. L., Love, S., & Kehoe, P. G. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2010.09.024 · Cited by 38 · see citing works

Single photon emission computed tomography imaging of cerebral blood flow, blood–brain barrier disruption, and apoptosis time course after focal cerebral ischemia in rats

Garrigue, P., Giacomino, L., Bucci, C., Muzio, V., Filannino, M. A., Sabatier, F., Dignat‐George, F., Pisano, P. S., & Guillet, B. A. (2015) · International Journal of Stroke · doi:10.1177/1747493015607516 · Cited by 32 · see citing works

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

Sweeney, M. D., Sagare, A. P., & Zlokovic, B. V. (2018) · Nature Reviews Neurology · doi:10.1038/nrneurol.2017.188 · Cited by 3,076 · see citing works

Blood-Brain Barrier: From Physiology to Disease and Back

Sweeney, M. D., Zhao, Z., Montagne, A., Nelson, A. R., & Zlokovic, B. V. (2019) · Physiological Reviews · doi:10.1152/physrev.00050.2017 · Cited by 2,294 · see citing works

The blood-brain barrier in aging and neurodegeneration

Knox, E. G., Aburto, M. R., Clarke, G., Cryan, J. F., & O’Driscoll, C. M. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01511-z · Cited by 738 · see citing works

Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics

Petersen, M. A., Ryu, J. K., & Akassoglou, K. (2018) · Nature reviews. Neuroscience · doi:10.1038/nrn.2018.13 · Cited by 527 · see citing works

Role of Blood-Brain Barrier in Alzheimer’s Disease

Cai, Z., Qiao, P.-F., Wan, C.-Q., Cai, M., Zhou, N.-K., & Li, Q. (2018) · Journal of Alzheimer's Disease · doi:10.3233/jad-180098 · Cited by 370 · see citing works

The neuroimmune axis of Alzheimer’s disease

Jorfi, M., Maaser‐Hecker, A., & Tanzi, R. E. (2023) · Genome Medicine · doi:10.1186/s13073-023-01155-w · Cited by 299 · see citing works

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

Ma, Q., Zhao, Z., Sagare, A. P., Wu, Y., Wang, M., Owens, N. C., Verghese, P. B., Herz, J., Holtzman, D. M., & Zlokovic, B. V. (2018) · Molecular Neurodegeneration · doi:10.1186/s13024-018-0286-0 · Cited by 281 · see citing works

Vascular Dysfunction in Alzheimer’s Disease: A Prelude to the Pathological Process or a Consequence of It?

Govindpani, K., McNamara, L. G., Smith, N. R., Vinnakota, C., Waldvogel, H. J., Faull, R. L. M., & Kwakowsky, A. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8050651 · Cited by 271 · see citing works

Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain

Berthiaume, A.-A., Grant, R. I., McDowell, K. P., Underly, R. G., Hartmann, D. A., Levy, M., Bhat, N. R., & Shih, A. Y. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.016 · Cited by 223 · see citing works

Fibrin(ogen) in human disease: both friend and foe

Vilar, R., Fish, R. J., Casini, A., & Neerman‐Arbez, M. (2020) · Haematologica · doi:10.3324/haematol.2019.236901 · Cited by 237 · see citing works

Cognitive impact of COVID-19: looking beyond the short term

Miners, J. S., Kehoe, P. G., & Love, S. (2020) · Alzheimer s Research & Therapy · doi:10.1186/s13195-020-00744-w · Cited by 248 · see citing works

Pericyte Control of Blood Flow Across Microvascular Zones in the Central Nervous System

Hartmann, D. A., Coelho‐Santos, V., & Shih, A. Y. (2021) · Annual Review of Physiology · doi:10.1146/annurev-physiol-061121-040127 · Cited by 212 · see citing works

White matter degeneration in vascular and other ageing‐related dementias

Hase, Y., Horsburgh, K. J., Ihara, M., & Kalaria, R. N. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.14271 · Cited by 207 · see citing works

Selective loss of cortical endothelial tight junction proteins during Alzheimer’s disease progression

Yamazaki, Y., Shinohara, M., Shinohara, M., Yamazaki, A., Murray, M. E., Liesinger, A. M., Heckman, M. G., Lesser, E. R., Parisi, J. E., Petersen, R. C., et al. (2019) · Brain · doi:10.1093/brain/awz011 · Cited by 202 · see citing works

Persistent neuropathological effects 14 years following amyloid-β immunization in Alzheimer’s disease

Nicoll, J. A. R., Buckland, G. R., Harrison, C. H., Page, A. M., Harris, S., Love, S., Neal, J., Holmes, C., & Boche, D. (2019) · Brain · doi:10.1093/brain/awz142 · Cited by 205 · see citing works

Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

Mäe, M. A., He, L., Nordling, S., Vázquez-Liébanas, E., Nahar, K., Jung, B., Li, X., Tan, B. C., Foo, J. C., Cazenave‐Gassiot, A., et al. (2020) · Circulation Research · doi:10.1161/circresaha.120.317473 · Cited by 203 · see citing works

Dysfunction of the blood–brain barrier in Alzheimer's disease: Evidence from human studies

Kurz, C., Walker, L., Rauchmann, B., & Perneczky, R. (2022) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12782 · Cited by 183 · see citing works

Tau Protein and Its Role in Blood–Brain Barrier Dysfunction

Michalicová, A., Majerová, P., & Kováč, A. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.570045 · Cited by 179 · see citing works

Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer’s disease

Mahoney, E. R., Dumitrescu, L., Moore, A. M., Cambronero, F. E., De Jager, P. L., Koran, M. E. I., Petyuk, V. A., Robinson, R. A. S., Goyal, S., Schneider, J. A., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-019-0458-5 · Cited by 150 · see citing works

Loss of capillary pericytes and the blood–brain barrier in white matter in poststroke and vascular dementias and Alzheimer’s disease

Ding, R., Hase, Y., Ameen‐Ali, K. E., Ndung'u, M., Stevenson, W., Barsby, J., Gourlay, R., Akinyemi, T. O., Akinyemi, R., Uemura, M. T., et al. (2020) · Brain Pathology · doi:10.1111/bpa.12888 · Cited by 142 · see citing works

Pericyte remodeling is deficient in the aged brain and contributes to impaired capillary flow and structure

Berthiaume, A., Schmid, F., Stamenković, S., Coelho‐Santos, V., Nielson, C. D., Weber, B., Majesky, M. W., & Shih, A. Y. (2022) · Nature Communications · doi:10.1038/s41467-022-33464-w · Cited by 136 · see citing works

CSF evidence of pericyte damage in Alzheimer’s disease is associated with markers of blood-brain barrier dysfunction and disease pathology

Miners, J. S., Kehoe, P. G., Love, S., Zetterberg, H., & Blennow, K. (2019) · Alzheimer s Research & Therapy · doi:10.1186/s13195-019-0534-8 · Cited by 137 · see citing works

Pathological changes within the cerebral vasculature in Alzheimer’s disease: New perspectives

Fisher, R. A., Miners, J. S., & Love, S. (2022) · Brain Pathology · doi:10.1111/bpa.13061 · Cited by 127 · see citing works

Blood-brain barrier leakage in Alzheimer’s disease: From discovery to clinical relevance

Nehra, G., Bauer, B., & Hartz, A. M. S. (2022) · Pharmacology &amp; Therapeutics · doi:10.1016/j.pharmthera.2022.108119 · Cited by 127 · see citing works

Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis

Berthiaume, A., Hartmann, D. A., Majesky, M. W., Bhat, N. R., & Shih, A. Y. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00210 · Cited by 112 · see citing works

An Integrated View on Vascular Dysfunction in Alzheimer’s Disease

Klohs, J. (2019) · Neurodegenerative Diseases · doi:10.1159/000505625 · Cited by 111 · see citing works

Approaches to CNS Drug Delivery with a Focus on Transporter-Mediated Transcytosis

Razzak, R. A., Florence, G. J., & Gunn‐Moore, F. J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20123108 · Cited by 115 · see citing works

A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s disease

Tsartsalis, S., Sleven, H., Fancy, N., Wessely, F., Smith, A. M., Willumsen, N., Cheung, T. K. D., Rokicki, M. J., Chau, V., Ifie, E., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-46630-z · Cited by 95 · see citing works

Pericyte implantation in the brain enhances cerebral blood flow and reduces amyloid-β pathology in amyloid model mice

Tachibana, M., Yamazaki, Y., Liu, C., Bu, G., & Kanekiyo, T. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.10.023 · Cited by 92 · see citing works

Extracellular Vesicles of Alzheimer’s Disease Patients as a Biomarker for Disease Progression

Aharon, A., Specktor, P., Ahmad, R. S., Horrany, N., Sabbach, A., Brenner, B., & Aharon‐Peretz, J. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02013-1 · Cited by 90 · see citing works

Mediators of cerebral hypoperfusion and blood‐brain barrier leakiness in Alzheimer’s disease, vascular dementia and mixed dementia

Tayler, H. M., Miners, J. S., Güzel, Ö., MacLachlan, R. A., & Love, S. (2021) · Brain Pathology · doi:10.1111/bpa.12935 · Cited by 90 · see citing works

Cardiovascular brain impulses in Alzheimer’s disease

Rajna, Z., Mattila, H., Huotari, N., Tuovinen, T., Krüger, J., Holst, S. C., Korhonen, V. O., Remes, A. M., Seppänen, T., Hennig, J., et al. (2021) · Brain · doi:10.1093/brain/awab144 · Cited by 90 · see citing works

Role of Oxidative Stress and Metal Toxicity in the Progression of Alzheimer’s Disease

Birla, H., Minocha, T., Kumar, G., Misra, A., & Singh, S. K. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200122122512 · Cited by 89 · see citing works

Interactions between glial cells and the blood-brain barrier and their role in Alzheimer's disease

Zhao, M., Jiang, X., Zhang, H., Sun, J., Pei, H., Ma, L., Cao, Y., & Li, H. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101483 · Cited by 85 · see citing works

Microvascular Alterations in Alzheimer's Disease

Steinman, J., Sun, H., & Feng, Z. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.618986 · Cited by 82 · see citing works

Magnetic Resonance Imaging of Blood–Brain Barrier permeability in Dementia

Chagnot, A., Barnes, S. R., & Montagne, A. (2021) · Neuroscience · doi:10.1016/j.neuroscience.2021.08.003 · Cited by 79 · see citing works

Pericyte Loss in Diseases

Li, P., & Fan, H. (2023) · Cells · doi:10.3390/cells12151931 · Cited by 79 · see citing works

The contribution of β-amyloid, Tau and α-synuclein to blood–brain barrier damage in neurodegenerative disorders

Wu, Y., Bogale, T. A., Koıstınaho, J., Pizzi, M., Rõlova, T., & Bellucci, A. (2024) · Acta Neuropathologica · doi:10.1007/s00401-024-02696-z · Cited by 81 · see citing works

Systemic infection exacerbates cerebrovascular dysfunction in Alzheimer’s disease

Asby, D. J., Boche, D., Allan, S. M., Love, S., & Miners, J. S. (2021) · Brain · doi:10.1093/brain/awab094 · Cited by 79 · see citing works

Small Vessels Are a Big Problem in Neurodegeneration and Neuroprotection

Erdener, Ş. E., & Dalkara, T. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00889 · Cited by 76 · see citing works

The microcirculation, the blood-brain barrier, and the neurovascular unit in health and Alzheimer disease: The aberrant pericyte is a central player

Divecha, Y. A., Rampes, S., Tromp, S., Boyanova, S., Fleckney, A. L., Fidanboylu, M., & Thomas, S. A. (2025) · Pharmacological Reviews · doi:10.1016/j.pharmr.2025.100052 · Cited by 79 · see citing works

A novel sensitive assay for detection of a biomarker of pericyte injury in cerebrospinal fluid

Sweeney, M. D., Sagare, A. P., Pachicano, M., Harrington, M. G., Joe, E., Chui, H. C., Schneider, L. S. S., Montagne, A., Ringman, J. M., Fagan, A. M., et al. (2020) · Alzheimer s & Dementia · doi:10.1002/alz.12061 · Cited by 74 · see citing works

Deficiency of Endothelial Nitric Oxide Synthase (eNOS) Exacerbates Brain Damage and Cognitive Deficit in A Mouse Model of Vascular Dementia

An, L., Shen, Y., Chopp, M., Zacharek, A., Venkat, P., Chen, Z., Li, W., Yu, Q., Landschoot‐Ward, J., & Chen, J. (2021) · Aging and Disease · doi:10.14336/ad.2020.0523 · Cited by 64 · see citing works

Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development

Vázquez-Liébanas, E., Nahar, K., Bertuzzi, G., Keller, A., Betsholtz, C., & Mäe, M. A. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211056395 · Cited by 67 · see citing works

Update of inflammasome activation in microglia/macrophage in aging and aging‐related disease

Hu, M., Lin, Y., Zhang, B., Lu, D., Lu, Z., & Cai, W. (2019) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13262 · Cited by 65 · see citing works

The Cause of Alzheimer’s Disease: The Theory of Multipathology Convergence to Chronic Neuronal Stress

Decourt, B., D’Souza, G. X., Shi, J., Ritter, A., Suazo, J., & Sabbagh, M. N. (2022) · Aging and disease · doi:10.14336/ad.2021.0529 · Cited by 69 · see citing works

A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain

Rust, R., Kirabali, T., Grönnert, L., Doğançay, B., Limasale, Y. D. P., Meinhardt, A., Werner, C., Laviña, B., Kulic, L., Nitsch, R. M., et al. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00244 · Cited by 62 · see citing works

Assessment of Inner Blood–Retinal Barrier: Animal Models and Methods

Bora, K., Kushwah, N. S., Maurya, M., Pavlovich, M. C., Wang, Z., & Chen, J. (2023) · Cells · doi:10.3390/cells12202443 · Cited by 65 · see citing works

The Active Role of Pericytes During Neuroinflammation in the Adult Brain

Medina‐Flores, F., Hurtado‐Alvarado, G., Deli, M. A., & Gómez‐González, B. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-022-01208-5 · Cited by 60 · see citing works

Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response

Yang, R., Qu, X.-Y., Xiao, S.-Y., Li, L., Xu, B.-J., Fu, J., Lv, Y., Amjad, N., Tan, C., Kim, K. S., et al. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1497-1 · Cited by 57 · see citing works

Precision Aging: Applying Precision Medicine to the Field of Cognitive Aging

Ryan, L., Hay, M., Huentelman, M. J., Duarte, A., Rundek, T., Levin, B. E., Soldan, A., Pettigrew, C. A., Mehl, M. R., & Barnes, C. A. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00128 · Cited by 54 · see citing works

Targeting Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-Related Factor 2) for the Intervention of Vascular Cognitive Impairment and Dementia

Yang, T., & Zhang, F. (2020) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.120.314804 · Cited by 52 · see citing works

What Are the Roles of Pericytes in the Neurovascular Unit and Its Disorders?

Benarroch, E. E. (2023) · Neurology · doi:10.1212/wnl.0000000000207379 · Cited by 53 · see citing works

Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer’s disease

Miners, J. S., Hulle, C. V., Ince, S., Jonaitis, E., Okonkwo, O., Bendlin, B. B., Johnson, S. C., Carlsson, C. M., Asthana, S., Love, S., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-023-02706-w · Cited by 53 · see citing works

The Pathway Coexpression Network: Revealing pathway relationships

Pita-Juárez, Y. H., Altschuler, G. M., Kariotis, S., Wei, W., Koler, K., Green, C., Tanzi, R. E., & Hide, W. (2018) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006042 · Cited by 53 · see citing works

The Post-amyloid Era in Alzheimer's Disease: Trust Your Gut Feeling

Osorio, C. P., Kanukuntla, T., Diaz, E. L., Jafri, N., Cummings, M., & Sfera, A. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00143 · Cited by 49 · see citing works

Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury

Yao, F., Luo, Y., Liu, Y.-C., Chen, Y., Li, Y.-T., Hu, X., You, X., Yu, S., Li, Z., Chen, L., et al. (2022) · Inflammation and Regeneration · doi:10.1186/s41232-022-00223-9 · Cited by 48 · see citing works

Mild pericyte deficiency is associated with aberrant brain microvascular flow in aged PDGFRβ +/− mice

Watson, A. N., Berthiaume, A., Faino, A., McDowell, K. P., Bhat, N. R., Hartmann, D. A., & Shih, A. Y. (2020) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x19900543 · Cited by 43 · see citing works

Aging Neurovascular Unit and Potential Role of DNA Damage and Repair in Combating Vascular and Neurodegenerative Disorders

Li, Y., Xie, L., Huang, T., Zhang, Y., Zhou, J., Qi, B., Wang, X., Chen, Z., & Li, P. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00778 · Cited by 46 · see citing works

Pericytes in Cerebrovascular Diseases: An Emerging Therapeutic Target

Su, X., Huang, L., Qu, Y., Xiao, D., & Mu, D. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00519 · Cited by 44 · see citing works

Microvascular pericytes in brain-associated vascular disease

Liu, Q., Yang, Y., & Fan, X. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109633 · Cited by 45 · see citing works

Interactions between Amyloid-Β Proteins and Human Brain Pericytes: Implications for the Pathobiology of Alzheimer’s Disease

Alcendor, D. J. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9051490 · Cited by 47 · see citing works

Biomarkers Assessing Endothelial Dysfunction in Alzheimer’s Disease

Custodia, A., Aramburu-Núñez, M., Rodríguez‐Arrizabalaga, M., Peleteiro, J. M. P., Vázquez‐Vázquez, L., Camino-Castiñeiras, J., Aldrey, J. M., Castillo, J., Ouro, A., Sobrino, T., et al. (2023) · Cells · doi:10.3390/cells12060962 · Cited by 44 · see citing works

Elevated PDGF‐BB from Bone Impairs Hippocampal Vasculature by Inducing PDGFR β Shedding from Pericytes

Liu, G., Wang, J., Wei, Z., Fang, C., Shen, K., Cheng, Q., Qi, C., Li, T., Gao, P., Wong, P. C., et al. (2023) · Advanced Science · doi:10.1002/advs.202206938 · Cited by 42 · see citing works

The role of pericytes in brain disorders: from the periphery to the brain

Hirunpattarasilp, C., Attwell, D., & de Freitas, F. S. S. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14725 · Cited by 43 · see citing works

Neural crest cell-derived pericytes act as pro-angiogenic cells in human neocortex development and gliomas

Girolamo, F., de Trizio, I., Errede, M., Longo, G., d’Amati, A., & Virgintino, D. (2021) · Fluids and Barriers of the CNS · doi:10.1186/s12987-021-00242-7 · Cited by 44 · see citing works

Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer’s disease

Yang, H., Yau, W. W., Carlyle, B. C., Trombetta, B. A., Zhang, C. M., Shirzadi, Z., Schultz, A. P., Pruzin, J. J., Fitzpatrick, C. D., Kirn, D. R., et al. (2024) · Brain · doi:10.1093/brain/awae034 · Cited by 42 · see citing works

Metabolic determinants of Alzheimer’s disease: A focus on thermoregulation

Tournissac, M., Leclerc, M., Valentin‐Escalera, J., Vandal, M., Bosoi, C. R., Planel, E., & Calon, F. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101462 · Cited by 41 · see citing works

The Emerging Scenario of the Gut–Brain Axis: The Therapeutic Actions of the New Actor Kefir against Neurodegenerative Diseases

Pereira, T. D. M. C., Côco, L. Z., Ton, A. M. M., Meyrelles, S. S., Campos‐Toimil, M., Campagnaro, B. P., & Vasquez, E. C. (2021) · Antioxidants · doi:10.3390/antiox10111845 · Cited by 43 · see citing works

Identification and Validation of Aging-Related Genes in Alzheimer’s Disease

Zhang, Q., Li, J., & Weng, L. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.905722 · Cited by 41 · see citing works

Distinct changes in all major components of the neurovascular unit across different neuropathological stages of Alzheimer's disease

Kirabali, T., Rust, R., Rigotti, S., Siccoli, A., Nitsch, R. M., & Kulic, L. (2020) · Brain Pathology · doi:10.1111/bpa.12895 · Cited by 43 · see citing works

Recent Development in the Understanding of Molecular and Cellular Mechanisms Underlying the Etiopathogenesis of Alzheimer’s Disease

Afsar, A., Castro, M. D. C. C., Soladogun, A. S., & Li, Z. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087258 · Cited by 42 · see citing works

Denser brain capillary network with preserved pericytes in Alzheimer's disease

Fernández‐Klett, F., Brandt, L., Fernández‐Zapata, C., Abuelnor, B., Middeldorp, J., Sluijs, J. A., Curtis, M. A., Faull, R. L. M., Harris, L. W., Bahn, S., et al. (2020) · Brain Pathology · doi:10.1111/bpa.12897 · Cited by 39 · see citing works

Loss with ageing but preservation of frontal cortical capillary pericytes in post-stroke dementia, vascular dementia and Alzheimer’s disease

Ding, R., Hase, Y., Burke, M., Foster, V., Stevenson, W., Polvikoski, T. M., & Kalaria, R. N. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01230-6 · Cited by 39 · see citing works

From Plaques to Pathways in Alzheimer’s Disease: The Mitochondrial-Neurovascular-Metabolic Hypothesis

Kazemeini, S., Nadeem-Tariq, A., Shih, R., Rafanan, J., Ghani, N., & Vida, T. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252111720 · Cited by 41 · see citing works

Brain mural cell loss in the parietal cortex in Alzheimer’s disease correlates with cognitive decline and TDP‐43 pathology

Bourassa, P., Tremblay, C., Schneider, J. A., Bennett, D. A., & Calon, F. (2020) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12599 · Cited by 36 · see citing works

Blood-brain barrier dysfunction as a potential therapeutic target for neurodegenerative disorders

Uprety, A. R., Kang, Y., & Kim, S. Y. (2021) · Archives of Pharmacal Research · doi:10.1007/s12272-021-01332-8 · Cited by 38 · see citing works

cAMP Compartmentalization in Cerebrovascular Endothelial Cells: New Therapeutic Opportunities in Alzheimer’s Disease

Viña, D., Seoane, N., Vasquez, E. C., & Campos‐Toimil, M. (2021) · Cells · doi:10.3390/cells10081951 · Cited by 39 · see citing works

Pericyte Loss Leads to Capillary Stalling Through Increased Leukocyte-Endothelial Cell Interaction in the Brain

Choe, Y.-G., Yoon, J., Joo, J., Kim, B., Hong, S. P., Koh, G. Y., Lee, D., Oh, W., & Jeong, Y. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.848764 · Cited by 37 · see citing works

The impact of α-synuclein aggregates on blood-brain barrier integrity in the presence of neurovascular unit cells

Hourfar, H., Aliakbari, F., Aqdam, S. R., Nayeri, Z., Bardania, H., Otzen, D. E., & Morshedi, D. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.12.134 · Cited by 36 · see citing works

Higher angiotensin-converting enzyme 2 (ACE2) levels in the brain of individuals with Alzheimer’s disease

Réveret, L., Leclerc, M., Émond, V., Tremblay, C., Loiselle, A., Bourassa, P., Bennett, D. A., Hébert, S. S., & Calon, F. (2023) · Acta Neuropathologica Communications · doi:10.1186/s40478-023-01647-1 · Cited by 36 · see citing works

Blood–Brain Barrier Dysfunction and the Potential Mechanisms in Chronic Cerebral Hypoperfusion Induced Cognitive Impairment

Xu, W., Bai, Q., Dong, Q., Guo, M., & Cui, M. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.870674 · Cited by 36 · see citing works

Emerging Links between Cerebral Blood Flow Regulation and Cognitive Decline: A Role for Brain Microvascular Pericytes

You, T.-Y., Dong, Q., & Cui, M. (2022) · Aging and Disease · doi:10.14336/ad.2022.1204 · Cited by 33 · see citing works

Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer’s disease and experimental chronic cerebral hypoperfusion

Hase, Y., Jobson, D., Cheong, J., Gotama, K. T., Maffei, L., Hase, M., Hamdan, A., Ding, R., Polivkoski, T., Horsburgh, K. J., et al. (2024) · Acta Neuropathologica Communications · doi:10.1186/s40478-024-01737-8 · Cited by 32 · see citing works

Dysregulation of sonic hedgehog pathway and pericytes in the brain after lentiviral infection

Bohannon, D. G., Ko, A., Filipowicz, A. R., Kuroda, M. J., & Kim, W. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1463-y · Cited by 31 · see citing works

Central Nervous System Pericytes Contribute to Health and Disease

Girolamo, F., Errede, M., Bizzoca, A., Virgintino, D., & Ribatti, D. (2022) · Cells · doi:10.3390/cells11101707 · Cited by 32 · see citing works

Blood brain barrier dysfunction in healthy aging and dementia: Why, how, what for?

Cunha, S., Bicker, J., Sereno, J., Falcão, A. C., & Fortuna, A. C. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102395 · Cited by 31 · see citing works

Single‐cell transcriptomic analysis of gingivo‐buccal oral cancer reveals two dominant cellular programs

Kurkalang, S., Roy, S., Acharya, A., Mazumder, P., Mazumder, S., Patra, S., Ghosh, S., Sarkar, S., Kundu, S., Biswas, N. K., et al. (2023) · Cancer Science · doi:10.1111/cas.15979 · Cited by 28 · see citing works

The role of platelets in the blood-brain barrier during brain pathology

Lv, W., Jiang, X., & Zhang, Y. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1298314 · Cited by 28 · see citing works

Dissection of blood–brain barrier dysfunction through CSF PDGFRβ and amyloid, tau, neuroinflammation, and synaptic CSF biomarkers in neurodegenerative disorders

Vrillon, A., Ashton, N. J., Bouaziz-Amar, É., Mouton‐Liger, F., Cognat, E., Dumurgier, J., Lilamand, M., Karikari, T. K., Prévot, V., Zetterberg, H., et al. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2025.105694 · Cited by 29 · see citing works

Pericytes in Alzheimer’s Disease: Novel Clues to Cerebral Amyloid Angiopathy Pathogenesis

Salmina, A. B., Komleva, Y. K., Lopatina, O. L., & Birbrair, A. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-16908-4_7 · Cited by 28 · see citing works

Concordant and Discordant Cerebrospinal Fluid and Plasma Cytokine and Chemokine Responses in Mild Cognitive Impairment and Early-Stage Alzheimer’s Disease

de la Monte, S. M., Tong, M., & Hapel, A. J. (2023) · Biomedicines · doi:10.3390/biomedicines11092394 · Cited by 27 · see citing works

Small vessel disease, neurovascular regulation and cognitive impairment: post-mortem studies reveal a complex relationship, still poorly understood

Love, S., & Miners, J. S. (2017) · Clinical Science · doi:10.1042/cs20170148 · Cited by 25 · see citing works

The Correlations Between Plasma Fibrinogen With Amyloid-Beta and Tau Levels in Patients With Alzheimer’s Disease

Fan, D.-Y., Sun, H.-L., Sun, P.-Y., Jian, J.-M., Li, W.-W., Shen, Y.-Y., Zeng, F., Wang, Y.-J., & Bu, X.-L. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.625844 · Cited by 27 · see citing works

The pericyte: A critical cell in the pathogenesis of CADASIL

Ruchoux, M., Kalaria, R. N., & Román, G. C. (2021) · Cerebral Circulation - Cognition and Behavior · doi:10.1016/j.cccb.2021.100031 · Cited by 26 · see citing works

Regional White Matter Hyperintensities and Alzheimer’s Disease Biomarkers Among Older Adults with Normal Cognition and Mild Cognitive Impairment

Newton, P., the BIOCARD Research Team, Tchounguen, J., Pettigrew, C., Lim, C., Lin, Z., Lu, H., Moghekar, A., Albert, M., & Soldan, A. (2023) · Journal of Alzheimer's Disease · doi:10.3233/jad-220846 · Cited by 23 · see citing works

Fibrin-targeting immunotherapy for dementia

Kantor, A. B., Akassoglou, K., & Stavenhagen, J. B. (2023) · The Journal of Prevention of Alzheimer's Disease · doi:10.14283/jpad.2023.105 · Cited by 24 · see citing works

Retinal peri-arteriolar versus peri-venular amyloidosis, hippocampal atrophy, and cognitive impairment: exploratory trial

Dumitrascu, O. M., Doustar, J., Fuchs, D.-T. S., Koronyo, Y., Sherman, D. S., Miller, M. S., Johnson, K., Carare, R. O., Verdooner, S. R., Lyden, P. D., et al. (2024) · Acta Neuropathologica Communications · doi:10.1186/s40478-024-01810-2 · Cited by 24 · see citing works

Crosstalk between soluble PDGF‐BB and PDGFRβ promotes astrocytic activation and synaptic recovery in the hippocampus after subarachnoid hemorrhage

Zhou, X., Wu, Q., Lu, Y., Zhang, X., Lv, S., Shao, J., Zhou, Y., Chen, J., Hou, L., Huang, C., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201900195r · Cited by 24 · see citing works

Tracking pericyte dysfunction in Alzheimer’s disease: The emerging role of cerebrospinal fluid platelet-derived growth factor receptor-β

Tsai, S., Liew, H., Wang, M.-J., Hung, W.-T., & Huang, H.-Y. (2026) · Tzu Chi Medical Journal · doi:10.4103/tcmj.tcmj-d-25-00173

Post-mortem evidence of pathogenic angiogenesis and abnormal vascular function in early Alzheimer’s disease

Asby, D. J., Fisher, R. A., Jackson, J., Love, S., Matthews, P. M., & Miners, J. S. (2025) · Brain · doi:10.1093/brain/awaf394 · Cited by 12 · see citing works

CSF evidence of pericyte damage in Alzheimer’s disease is associated with markers of blood-brain barrier dysfunction and disease pathology

Miners, J. S., Kehoe, P. G., Love, S., Zetterberg, H., & Blennow, K. (2019) · Alzheimer s Research & Therapy · doi:10.1186/s13195-019-0534-8 · Cited by 137 · see citing works

Mediators of cerebral hypoperfusion and blood‐brain barrier leakiness in Alzheimer’s disease, vascular dementia and mixed dementia

Tayler, H. M., Miners, J. S., Güzel, Ö., MacLachlan, R. A., & Love, S. (2021) · Brain Pathology · doi:10.1111/bpa.12935 · Cited by 90 · see citing works

Pericytes in Alzheimer’s Disease: A Morphometric Analysis

Brandt, L. (2022) · doi:10.17169/refubium-31567