Clock Genes, Oscillators, and Cellular Networks in the Suprachiasmatic Nuclei

Coordination of circadian timing in mammals

Reppert, S. M., & Weaver, D. R. (2002) · Nature · doi:10.1038/nature00965 · Cited by 4,379

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes & Development · doi:10.1101/gad.183500 · Cited by 2,394

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308709101 · Cited by 2,329

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,310

The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

Preitner, N., Damiola, F., Luis-Lopez-Molina, Zakany, J., Duboule, D., Albrecht, U., & Schibler, U. (2002) · Cell · doi:10.1016/s0092-8674(02)00825-5 · Cited by 2,198

Resetting central and peripheral circadian oscillators in transgenic rats

Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907

Entrainment of the circadian clock in the liver by feeding

Stokkan, K.-A., Yamazaki, S., Tei, H., Sakaki, Y., & Menaker, M. (2001) · Science · doi:10.1126/science.291.5503.490 · Cited by 1,800

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms

Welsh, D. K., Logothetis, D. E., Meister, M., & Reppert, S. M. (1995) · Neuron · doi:10.1016/0896-6273(95)90214-7 · Cited by 1,481

An h Per2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

Toh, K. L., Jones, C. R., He, Y., Eide, E. J., Hinz, W. A., Virshup, D. M., Ptáček, L. J., & Fu, Y.-H. (2001) · Science · doi:10.1126/science.1057499 · Cited by 1,460

Interacting molecular loops in the mammalian circadian clock

Shearman, L. P., Sriram, S., Weaver, D. R., Maywood, E. S., Chaves, I., Zheng, B., Kume, K., Lee, C. C., van der, G. T. J., Horst, et al. (2000) · Science · doi:10.1126/science.288.5468.1013 · Cited by 1,367

Circadian rhythms from multiple oscillators: lessons from diverse organisms

Bell‐Pedersen, D., Cassone, V. M., Earnest, D. J., Golden, S. S., Hardin, P. E., Thomas, T. L., & Zoran, M. J. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1633 · Cited by 1,523

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

Welsh, D. K., Takahashi, J. S., & Kay, S. A. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135919 · Cited by 1,216

Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network

Liu, A. C., Welsh, D. K., Ko, C. H., Tran, H. G., Zhang, E. E., Priest, A. A., Buhr, E. D., Singer, O., Meeker, K., Verma, I. M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.02.047 · Cited by 711

Spontaneous Synchronization of Coupled Circadian Oscillators

Gonze, D., Bernard, S., Waltermann, C., Kramer, A., & Herzel, H. (2005) · Biophysical Journal · doi:10.1529/biophysj.104.058388 · Cited by 462

Synchronization and Maintenance of Timekeeping in Suprachiasmatic Circadian Clock Cells by Neuropeptidergic Signaling

Maywood, E. S., Reddy, A. B., Wong, G. K. Y., O'Neill, J. S., O'Brien, J. A., McMahon, D. G., Harmar, A. J., Okamura, H., & Hastings, M. H. (2006) · Current Biology · doi:10.1016/j.cub.2006.02.023 · Cited by 438

Circadian clocks: regulators of endocrine and metabolic rhythms

Hastings, M., O’Neill, J. S., & Maywood, E. S. (2007) · Journal of Endocrinology · doi:10.1677/joe-07-0378 · Cited by 426

Modeling of a Human Circadian Mutation Yields Insights into Clock Regulation by PER2

Xu, Y., Toh, K. L., Jones, C. R., Shin, J., Fu, Y., & Ptáček, L. J. (2007) · Cell · doi:10.1016/j.cell.2006.11.043 · Cited by 409

Melatonin: Both master clock output and internal time-giver in the circadian clocks network

Pévet, P., & Challet, É. (2011) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2011.07.001 · Cited by 372

Minireview: Entrainment of the Suprachiasmatic Clockwork in Diurnal and Nocturnal Mammals

Challet, É. (2007) · Endocrinology · doi:10.1210/en.2007-0804 · Cited by 356

Interplay of Circadian Clocks and Metabolic Rhythms

Wijnen, H., & Young, M. W. (2006) · Annual Review of Genetics · doi:10.1146/annurev.genet.40.110405.090603 · Cited by 341

Acute Physical Stress Elevates Mouse Period1 mRNA Expression in Mouse Peripheral Tissues via a Glucocorticoid-responsive Element

Yamamoto, T., Nakahata, Y., Tanaka, M., Yoshida, M., Soma, H., Shinohara, K., Yasuda, A., Mamine, T., & Takumi, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m509600200 · Cited by 309

SCFβ-TRCP Controls Clock-dependent Transcription via Casein Kinase 1-dependent Degradation of the Mammalian Period-1 (Per1) Proteinm

Shirogane, T., Jin, J., Cambronne, X. A., & Harper, J. W. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502862200 · Cited by 296

Come Together, Right…Now: Synchronization of Rhythms in a Mammalian Circadian Clock

Aton, S. J., & Herzog, E. D. (2005) · Neuron · doi:10.1016/j.neuron.2005.11.001 · Cited by 288

Regulation of Clock-Controlled Genes in Mammals

Bożek, K., Relógio, A., Kiełbasa, S. M., Heine, M., Dame, C., Kramer, A., & Herzel, H. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004882 · Cited by 289

Circadian clocks: setting time by food

Mendoza, J. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01510.x · Cited by 257

BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output

Meredith, A. L., Wiler, S. W., Miller, B. H., Takahashi, J. S., Fodor, A. A., Ruby, N. F., & Aldrich, R. W. (2006) · Nature Neuroscience · doi:10.1038/nn1740 · Cited by 255

Review: Replication of cortisol circadian rhythm: new advances in hydrocortisone replacement therapy

Chan, S., & Debono, M. (2010) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/2042018810380214 · Cited by 243

Transcriptional Profiling in the Adrenal Gland Reveals Circadian Regulation of Hormone Biosynthesis Genes and Nucleosome Assembly Genes

Oster, H., Damerow, S., Hut, R. A., & Gregor Eichele, C. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406293053 · Cited by 233

Tracking the seasons: the internal calendars of vertebrates

Paul, M. J., Zucker, I., & Schwartz, W. J. (2007) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2007.2143 · Cited by 204

Human circadian rhythms: physiological and therapeutic relevance of light and melatonin

Skene, D. J., & Arendt, J. (2006) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1258/000456306778520142 · Cited by 210

Daily Electrical Silencing in the Mammalian Circadian Clock

Belle, M. D. C., Diekman, C. O., Forger, D. B., & Piggins, H. D. (2009) · Science · doi:10.1126/science.1169657 · Cited by 180

Treatment with synthetic glucocorticoids and the hypothalamus-pituitary-adrenal axis

Paragliola, R. M., Papi, G., Pontecorvi, A., & Corsello, S. M. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18102201 · Cited by 181

Inactivation of the microRNA -183/96/182 cluster results in syndromic retinal degeneration

Lumayag, S., Haldin, C. E., Corbett, N. J., Wahlin, K. J., Cowan, C. E., Turturro, S. B., Larsen, P. E., Kovacs, B., Witmer, P. D., Valle, D. L., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1212655110 · Cited by 186

A riot of rhythms: neuronal and glial circadian oscillators in the mediobasal hypothalamus

Guilding, C., Hughes, A. T. L., Brown, T. M., Namvar, S., & Piggins, H. D. (2009) · Molecular Brain · doi:10.1186/1756-6606-2-28 · Cited by 176

Mammalian Seasonal Rhythms: Behavior and Neuroendocrine Substrates

Stevenson, T. J., Prendergast, B. J., & Nelson, R. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803592-4.00013-4 · Cited by 169

Intrinsic and Extrinsic Light Responses in Melanopsin-Expressing Ganglion Cells During Mouse Development

Schmidt, T. M., Taniguchi, K., & Kofuji, P. (2008) · Journal of Neurophysiology · doi:10.1152/jn.00062.2008 · Cited by 171

Excitatory Actions of GABA in the Suprachiasmatic Nucleus

Choi, H. J., Lee, C. J., Schroeder, A., Kim, Y. S., Jung, S. H., Kim, J. S., Kim, D. Y., Son, E. J., Han, H. C., Hong, S. K., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5750-07.2008 · Cited by 167

Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei

Prosser, H. M., Bradley, A., Chesham, J. E., Ebling, F. J. P., Hastings, M. H., & Maywood, E. S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606884104 · Cited by 171

Diurnal differences in dopamine transporter and tyrosine hydroxylase levels in rat brain: dependence on the suprachiasmatic nucleus

Sleipness, E. P., Sorg, B. A., & Jansen, H. T. (2007) · Brain Research · doi:10.1016/j.brainres.2006.10.063 · Cited by 160

Attenuated Circadian Rhythms in Mice Lacking theProkineticin 2Gene

Li, J., Hu, W., Boehmer, L. N., Cheng, M., Lee, A. G., Jilek, A., Siegel, J. M., & Zhou, Q. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3679-06.2006 · Cited by 168

GABA and G i/o differentially control circadian rhythms and synchrony in clock neurons

Aton, S. J., Huettner, J. E., Straume, M., & Herzog, E. D. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607466103 · Cited by 156

Cellular Circadian Pacemaking and the Role of Cytosolic Rhythms

Hastings, M. H., Maywood, E. S., & O'Neill, J. S. (2008) · Current Biology · doi:10.1016/j.cub.2008.07.021 · Cited by 161

The circadian clock stops ticking during deep hibernation in the European hamster

Revel, F. G., Herwig, A., Garidou, M., Dardente, H., Menet, J. S., Masson‐Pévet, M., Simonneaux, V., Saboureau, M., & Pévet, P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704699104 · Cited by 148

Circadian Clock Gene Expression in the Ovary: Effects of Luteinizing Hormone1

Karman, B. N., & Tischkau, S. A. (2006) · Biology of Reproduction · doi:10.1095/biolreprod.106.050732 · Cited by 149

Aging of the circadian system in zebrafish and the effects of melatonin on sleep and cognitive performance

Zhdanova, I. V., Yu, L., López‐Patiño, M. A., Shang, E. H. H., Kishi, S., & Guélin, E. (2007) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2007.10.053 · Cited by 148

The neuroendocrine control of the circadian system: Adolescent chronotype

Hagenauer, M. H., & Lee, T. M. (2012) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2012.04.003 · Cited by 143

Circadian rhythms in exercise performance: implications for hormonal and muscular adaptation.

Teo, W., Newton, M. J., & McGuigan, M. R. (2011) · Europe PMC (PubMed Central) · Cited by 140

Circadian gene expression is resilient to large fluctuations in overall transcription rates

Dibner, C., Sage, D., Unser, M. A., Bauer, C. R., d’Eysmond, T., Naef, F., & Schibler, U. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.262 · Cited by 137

Potential role for peripheral circadian clock dyssynchrony in the pathogenesis of cardiovascular dysfunction

Young, M. E., & Bray, M. S. (2007) · Sleep Medicine · doi:10.1016/j.sleep.2006.12.010 · Cited by 129

The importance of circadian rhythms on drug response in hypertension and coronary heart disease—from mice and man

Lemmer, B. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.11.008 · Cited by 130

Transcriptional Feedback Oscillators: Maybe, Maybe Not...

Lakin‐Thomas, P. L. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730405286102 · Cited by 125

Circadian rhythms of extracellular ATP accumulation in suprachiasmatic nucleus cells and cultured astrocytes

Womac, A. D., Burkeen, J. F., Neuendorff, N., Earnest, D. J., & Zoran, M. J. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06874.x · Cited by 123

Daily and seasonal adaptation of the circadian clock requires plasticity of the SCN neuronal network

Meijer, J. H., Michel, S., VanderLeest, H. T., & Rohling, J. H. T. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07522.x · Cited by 119

Neurotransmitters of the suprachiasmatic nuclei

Reghunandanan, V., & Reghunandanan, R. (2006) · Journal of Circadian Rhythms · doi:10.1186/1740-3391-4-2 · Cited by 123

Minireview: The Circadian Clockwork of the Suprachiasmatic Nuclei—Analysis of a Cellular Oscillator that Drives Endocrine Rhythms

Maywood, E. S., O'Neill, J. S., Chesham, J. E., & Hastings, M. H. (2007) · Endocrinology · doi:10.1210/en.2007-0660 · Cited by 119

The dynamics of GABA signaling: Revelations from the circadian pacemaker in the suprachiasmatic nucleus

Albers, H. E., Walton, J. C., Gamble, K. L., McNeill, J. K., & Hummer, D. L. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2016.11.003 · Cited by 117

Oxytocin and vasopressin: genetics and behavioral implications

Caldwell, H. K., & Young, W. S. (2006) · Handbook of Neurochemistry and Molecular Neurobiology · doi:10.1007/978-0-387-30381-9_25 · Cited by 113

Probing the Relative Importance of Molecular Oscillations in the Circadian Clock

Zheng, X., & Sehgal, A. (2008) · Genetics · doi:10.1534/genetics.107.088658 · Cited by 112

Exploring Spatiotemporal Organization of SCN CircuitsPreprint

Yan, L., Karatsoreos, I. N., LeSauter, J., Welsh, D. K., Kay, S. A., Foley, D. K., & Silver, R. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.037 · Cited by 112

Global climate change and invariable photoperiods: A mismatch that jeopardizes animal fitness

Walker, W. H., Meléndez‐Fernández, O. H., Nelson, R. J., & Reiter, R. J. (2019) · Ecology and Evolution · doi:10.1002/ece3.5537 · Cited by 107

The Role of Clock Genes in Pharmacology

Paschos, G. K., Baggs, J. E., Hogenesch, J. B., & FitzGerald, G. A. (2010) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.010909.105621 · Cited by 105

Regulation of Circadian Gene Expression in Liver by Systemic Signals and Hepatocyte OscillatorsPreprint

Kornmann, B., Schaad, O., Reinke, H., Saini, C., & Schibler, U. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.041 · Cited by 102

Functional magnetic resonance imaging in episodic cluster headache

Morelli, N., Pesaresi, I., Cafforio, G., Maluccio, M. R., Gori, S., Salle, F. D., & Murri, L. (2008) · The Journal of Headache and Pain · doi:10.1007/s10194-008-0085-z · Cited by 97

The Circadian Clock, the Immune System, and Viral Infections: The Intricate Relationship Between Biological Time and Host-Virus Interaction

Mazzoccoli, G., Vinciguerra, M., Carbone, A., & Relógio, A. (2020) · Pathogens · doi:10.3390/pathogens9020083 · Cited by 91

TheNeurospora crassaWhite Collar-1 dependent Blue Light Response Requires Acetylation of Histone H3 Lysine 14 by NGF-1

Grimaldi, B., Coiro, P., Filetici, P., Berge, E., Dobosy, J. R., Freitag, M., Selker, E. U., & Ballario, P. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-03-0232 · Cited by 86

Global parameter search reveals design principles of the mammalian circadian clock

Locke, J. C. W., Westermark, P. O., Kramer, A., & Herzel, H. (2008) · BMC Systems Biology · doi:10.1186/1752-0509-2-22 · Cited by 85

Connexin36 vs. Connexin32, “miniature” neuronal gap junctions, and limited electrotonic coupling in rodent suprachiasmatic nucleus

Rash, J. E., Olson, C. O., Pouliot, W. A., Davidson, K. G. V., Yasumura, T., Furman, C. S., Royer, S., Kamasawa, N., Nagy, J. I., & Dudek, F. E. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.06.052 · Cited by 82

Rodent models of insomnia: A review of experimental procedures that induce sleep disturbances

Revel, F. G., Gottowik, J., Gatti, S., Wettstein, J. G., & Moreau, J. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.03.002 · Cited by 90

Circadian Modulation of Gene Expression, but not Glutamate Uptake, in Mouse and Rat Cortical Astrocytes

Beaulé, C., Swanstrom, A. E., Leone, M. J., & Herzog, E. D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007476 · Cited by 86

Mitochondrial Calcium Signaling Mediates Rhythmic Extracellular ATP Accumulation in Suprachiasmatic Nucleus Astrocytes

Burkeen, J. F., Womac, A. D., Earnest, D. J., & Zoran, M. J. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6576-10.2011 · Cited by 79

Human studies on hypothalamo-pituitary-adrenal (HPA) axis

Liyanarachchi, K., Ross, R. J. M., & Debono, M. (2017) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2017.10.011 · Cited by 83

Circadian time-keeping during early stages of development

Ziv, L., & Gothilf, Y. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600571103 · Cited by 74

Mathematical modeling of circadian rhythms

Asgari-Targhi, A., & Klerman, E. B. (2018) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1439 · Cited by 73

Synchronization and entrainment of coupled circadian oscillators

Komin, N., Murza, A. C., Hernández-Garcı́a, E., & Toral, R. (2010) · Interface Focus · doi:10.1098/rsfs.2010.0327 · Cited by 65

Single Gene Deletions of Orexin, Leptin, Neuropeptide Y, and Ghrelin Do Not Appreciably Alter Food Anticipatory Activity in Mice

Gunapala, K. M., Gallardo, C. M., Hsu, C. T., & Steele, A. D. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018377 · Cited by 66

A non-canonical E-box within the MyoD core enhancer is necessary for circadian expression in skeletal muscle

Zhang, X., Patel, S. P., McCarthy, J. J., Rabchevsky, A. G., Goldhamer, D. J., & Esser, K. A. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr1297 · Cited by 67

Dim light at night disrupts the short-day response in Siberian hamsters

Ikeno, T., Weil, Z. M., & Nelson, R. J. (2013) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2013.12.005 · Cited by 62

Noise-Induced Coherence in Multicellular Circadian Clocks

Ullner, E., Buceta, J., Dı́ez-Noguera, A., & García‐Ojalvo, J. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2009.02.031 · Cited by 60

Live imaging of altered period1 expression in the suprachiasmatic nuclei of Vipr2−/− mice1

Hughes, A. T. L., Guilding, C., Lennox, L., Samuels, R. E., McMahon, D. G., & Piggins, H. D. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05520.x · Cited by 59

Emerging links between the biological clock and the DNA damage response

Collis, S. J., & Boulton, S. J. (2007) · Chromosoma · doi:10.1007/s00412-007-0108-6 · Cited by 60

Light-Dependent Regulation of Sleep and Wake States by Prokineticin 2 in Zebrafish

Chen, S., Reichert, S., Singh, C., Oikonomou, G., Rihel, J., & Prober, D. A. (2017) · Neuron · doi:10.1016/j.neuron.2017.06.001 · Cited by 62

Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells

Osland, T. M., Fernø, J., Håvik, B., Heuch, I., Ruoff, P., Lærum, O. D., & Steen, V. M. (2010) · Journal of Psychopharmacology · doi:10.1177/0269881110379508 · Cited by 56

BK Channels Regulate Spontaneous Action Potential Rhythmicity in the Suprachiasmatic Nucleus

Kent, J., & Meredith, A. L. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003884 · Cited by 54

Changes of physiological functions induced by shift work

Herichová, I. (2013) · Endocrine Regulations · doi:10.4149/endo_2013_03_159 · Cited by 51

Light, dark, and melatonin: emerging evidence for the importance of melatonin in ocular physiology

Brennan, R., Jan, J. E., & Lyons, C. J. (2006) · Eye · doi:10.1038/sj.eye.6702597 · Cited by 52

PDF Cycling in the Dorsal Protocerebrum of the Drosophila Brain Is Not Necessary for Circadian Clock Function

Kula-Eversole, E., Levitan, E. S., Pyza, E., & Rosbash, M. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730405285715 · Cited by 50

Symptom clusters in cancer patients and their relation to EGFR ligand modulation of the circadian axis.

Rich, T. A. (2007) · PubMed · Cited by 49

Decoding the nightly melatonin signal through circadian clockwork

Lincoln, G. A. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.03.006 · Cited by 50

Are Circadian Rhythms the Code of Hypothalamic-Immune Communication? Insights from Natural Killer Cells

Arjona, A., & Sarkar, D. K. (2008) · Neurochemical Research · doi:10.1007/s11064-007-9501-z · Cited by 60

Narrative review: The role of circadian rhythm on sports performance, hormonal regulation, immune system function, and injury prevention in athletes

Nobarı, H., Azarian, S., Saedmocheshi, S., Valdés-Badilla, P., & García‐Calvo, T. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e19636 · Cited by 59

Time is of the essence: Coupling sleep-wake and circadian neurobiology to the antidepressant effects of ketamine

Kohtala, S., Alitalo, O., Rosenholm, M., Rozov, S. V., & Rantamäki, T. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107741 · Cited by 47

Altered sleep and behavioral activity phenotypes in PER3-deficient mice

Hasan, S., van der Veen, D. R., Winsky‐Sommerer, R., Dijk, D., & Archer, S. N. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00260.2011 · Cited by 50

Melatonin receptors as therapeutic targets in the suprachiasmatic nucleus

Pévet, P. (2016) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2016.1179284 · Cited by 49

Assessment of diurnal urinary cortisol excretion in Asian and African elephants using different endocrine methods

Brown, J. L., Kersey, D. C., Freeman, E. W., & Wagener, T. (2010) · Zoo Biology · doi:10.1002/zoo.20268 · Cited by 47

Modeling circadian clocks: From equations to oscillations

Gonze, D. (2011) · Open Life Sciences · doi:10.2478/s11535-011-0061-5 · Cited by 47

Mechanism, autonomy and biological explanation

Bich, L., & Bechtel, W. (2021) · Biology & Philosophy · doi:10.1007/s10539-021-09829-8 · Cited by 53

Period gene expression in the diurnal degu (Octodon degus) differs from the nocturnal laboratory rat (Rattus norvegicus)

Vosko, A. M., Hagenauer, M. H., Hummer, D. L., & Lee, T. M. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90392.2008 · Cited by 45

Circadian Rhythms: Perturbing a Food-Entrained Clock

Mistlberger, R. E. (2006) · Current Biology · doi:10.1016/j.cub.2006.10.020 · Cited by 44

The central molecular clock is robust in the face of behavioural arrhythmia in aDrosophilamodel of Alzheimer's disease

Chen, K., Possidente, B. P., Lomas, D. A., & Crowther, D. C. (2014) · Disease Models & Mechanisms · doi:10.1242/dmm.014134 · Cited by 45

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(2012) · Handbook of Clinical Neurology · doi:10.1016/b978-0-444-52002-9.00042-5 · Cited by 42

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