Impact of Exposure to Childhood Maltreatment on Transitions to Alcohol Dependence in Women and Men
Open accessAbstract
Background: Childhood maltreatment decreases age of first use and speeds the transition from first use to dependence (i.e., telescoping) for alcohol use, however, it is currently unknown whether this influence is the same for men and women. Method: Analyses were conducted with the National Epidemiologic Survey on Alcohol and Related Conditions ( n = 34,653). Outcome variables included age of alcohol initiation and time to onset of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition alcohol dependence. Predictor variables included gender and childhood maltreatment. Linear and Poisson regression analyses were conducted. Results: Results demonstrated that in regard to age of drinking initiation, individuals who experienced childhood maltreatment initiated 1 year earlier than those without maltreatment, however, there was no interaction of this relationship with gender. Regarding the time to dependence, it was found that women who experienced childhood maltreatment demonstrated telescoping (shorter time between onset and dependence) compared to women without maltreatment and men (both with and without maltreatment). Conclusion: Women with a history of childhood maltreatment are particularly vulnerable to an accelerated time from initiation of alcohol use until dependence, a pattern indicative of increased negative alcohol-related outcomes. Findings highlight the need for development of gender-specific prevention efforts and behavioral treatments to aid in early intervention of problematic alcohol use in women.
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Childhood trauma is associated with higher rates of risky alcohol use, earlier drinking onset, and alcohol use disorder diagnosis.
“as well as increased rates of risky alcohol use, younger drinking onset, and alcohol use disorder (AUD) diagnosis (3–7).”
From Impact of Childhood Trauma on Executive Function in Adolescence—Mediating Functional Brain Networks and Prediction of High-Risk Drinking (2020) · cites this paper as [6]
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Xie, W.-Y., Emery, C. R., Liu, A. Y., Ng, S., Choi, A., & Chui, C. (2023) · Development and Psychopathology · doi:10.1017/s0954579423001098 · Cited by 1 · see citing works
“…emotional abuse is associated with AUD in both men and women, but there is increasing evidence arguing that maltreated women tend to experience more significant alcohol-related health problems than men (Cheng & Anthony, 2018; Guinle & Sinha, 2020; McCaul et al., 2019; Oberleitner et al., 2015).”
The Role of Trauma in Addiction and Recovery: A Qualitative Meta-Synthesis
Kim, J., Kim, M., Shin, Y.-J., Kim, B., & Kim, S. (2021) · Stress · doi:10.17547/kjsr.2021.29.1.45 · Cited by 1 · see citing works
“또한 미국의 알코올 및 관련상태에 대한 국가역학조 사(National Epidemiologic Survey on Alcohol and Related Conditions)에서는 아동학대를 경험한 사람이 그렇지 않은 사람보다 1년 먼저 알코올을 사용하기 시작 한다고 밝혔다[18,19].”
Vitus, D., Montemayor, B., & Vujanovic, A. A. (2026) · Substance Use & Misuse · doi:10.1080/10826084.2026.2734265
Rötzer, L., Zaiser, J., Hoffmann, S., Hiß, I., Reinhard, I., Heim, C., Tost, H., Kiefer, F., Lenz, B., & Bach, P. (2026) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20251163
Hinojosa, C. A., DelRosario, D., Davis, M., Roeckner, A. R., Oliver, K. I., Taylor, L. S., Santos, J. L., Dahlgren, K., Ely, T., Zeleke, H., et al. (2026) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2026.06.004
Structural Covariance Network Properties Predictive of Early Adolescent Alcohol InitiationPreprint
Byrne, H., Visontay, R., Devine, E., Wade, N., Jacobus, J., Squeglia, L., & Mewton, L. (2025) · bioRxiv · doi:10.1101/2025.05.08.652983
“…alcohol initiators reduced our capacity to examine other, more nuanced contributing factors linked to early alcohol initiation, such as peer influence 53 , family history of alcohol use 54 , and childhood trauma 55 , which is central to understanding the broader picture of early alcohol initiation.”
Abshire, K. M., Schwandt, M., Diazgranados, N., Farokhnia, M., & Leggio, L. (2025) · Alcohol, clinical & experimental research · doi:10.1111/acer.15537
Olsavsky, A. K., Chirico, I. S., Ali, D. A., Christensen, H., Boggs, B., Svete, L. J., Ketcham, K., Hutchison, K. E., Zeanah, C. H., Tottenham, N., et al. (2023) · Substance Abuse Research and Treatment · doi:10.1177/11782218231186371 · Cited by 1 · see citing works
Ondersma, S. J., McGoron, L., & Beatty, J. R. (2017) · Merrill-Palmer quarterly · doi:10.13110/merrpalmquar1982.63.1.0135
- Authors
- Oberleitner, L. M. S., Smith, P. H., Weinberger, A. H., Mazure, C. M., & McKee, S. A.
- Affiliations
- Yale University (US)
- Yeshiva University (US)
- Yale Cancer Center (US)
- Corresponding author
- Oberleitner, Lindsay M. S.
- Venue
- Child Maltreatment
- Publisher
- SAGE Publications
- Published
- 2015-06-30
- Volume
- 20
- Issue
- 4
- Pages
- 301-308
- ISSN
- 1077-5595 (ISSN-L)
- 1552-6119
- PMC
- PMC4868049
- OpenAlex
- W1840228541
- Cited by
- 43
- References
- 39
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 7 · 2021: 5 · 2020: 1 · 2019: 7 · 2018: 6 · 2017: 3 · 2016: 1
- FWCI
- 4.13
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Child Maltreatment (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (K12DA031050, P50DA033945, T32DA007238)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Safety Research › Child Welfare and Adoption
- Keywords
- child abuse, alcoholism, age of alcohol initiation, telescoping, gender differences, women, alcohol abuse, gender-specific prevention
- MeSH terms
- Adolescent, Alcohol Drinking, Alcoholism, Female, Humans, Male, Risk Factors, Sex Factors, Age of Onset, Adult Survivors of Child Abuse, Young Adult
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