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Cited by 910Substance Abuse Treatment and OutcomesGambling Behavior and TreatmentsOpioid Use Disorder Treatment

Gender differences in substance use disorders

Brady, Kathleen T., Randall, Carrie L.·1999·Psychiatric Clinics of North America
DOI 10.1016/s0193-953x(05)70074-5
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Abstract

Despite the fact that the rate of substance abuse and dependence is higher among men than it is among women, the prevalence rates, especially the more recent ones, indicate that a diagnosis of substance abuse is not gender specific. From the emerging literature on gender differences over the past 25 years, male and female substance abusers are clearly not the same. Women typically begin using substances later than do men, are strongly influenced by spouses or boyfriends to use, report different reasons for maintaining the use of the substances, and enter treatment earlier in the course of their illnesses than do men. Importantly, women also have a significantly higher prevalence of comorbid psychiatric disorders, such as depression and anxiety, than do men, and these disorders typically predate the onset of substance-abuse problems. For women, substances such as alcohol may be used to self-medicate mood disturbances, whereas for men, this may not be true. Although these comorbid disorders might complicate treatment for women, women are, in fact, responsive to treatment and do as well as men in follow-up. Gender differences and similarities have significant treatment implications. This is especially true for the telescoping phenomenon, in which the window for intervention between progressive landmarks is shorter for women than for men. This is also true for the gender differences in physical and sexual abuse, as well as other psychiatric comorbidity that is evident in female s…

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  • Women who become addicted to opioids progress from initial use to dependence at a faster rate than men.

    “For opioids, clinical reports indicate that women who become addicted to opioids progress through the stages of addiction, from initial use to dependence, at a faster rate than men (Brady and Randall, 1999).”

    From Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development (2021) · cites this paper as Brady and Randall, 1999

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Authors
Brady, K. T., & Randall, C. L.
Affiliations
Medical University of South Carolina (US)
ORCID
Brady, Kathleen T.
Venue
Psychiatric Clinics of North America
Publisher
Elsevier BV
Published
1999-06
Volume
22
Issue
2
Pages
241-252
ISSN
0193-953X (ISSN-L)
DOI
10.1016/s0193-953x(05)70074-5
OpenAlex
W2148152055
Cited by
910
References
4
Citations by year
2026: 17 · 2025: 19 · 2024: 40 · 2023: 37 · 2022: 38 · 2021: 45 · 2020: 105 · 2019: 42 · 2018: 42 · 2017: 35 · 2016: 57 · 2015: 52 · 2014: 28 · 2013: 52 · 2012: 43
FWCI
6.86
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Psychiatric Clinics of North America (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Keywords
gender differences, substance use disorders, women, alcohol consumption, self-medication, psychiatric comorbidity, depression, anxiety, barriers to treatment, family therapy, couple therapy, physical and sexual abuse, treatment outcomes
MeSH terms
Alcohol Drinking, Anxiety Disorders, Depressive Disorder, Female, Humans, Male, Psychotherapy, Sex Characteristics, Social Adjustment, Socioeconomic Factors, Comorbidity, Women's Health, Sex Distribution, Disease Progression, Substance-Related Disorders

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