Persistence of naive CD45RA+ regulatory T cells in adult life

Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>

Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187 · see citing works

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Fontenot, J. D., Gavin, M. A., & Rudensky, A. Y. (2003) · Nature Immunology · doi:10.1038/ni904 · Cited by 7,745 · see citing works

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G., & Glimcher, L. H. (2000) · Cell · doi:10.1016/s0092-8674(00)80702-3 · Cited by 3,589 · see citing works

N aturally A rising CD4+R egulatory T C ells for I mmunologic S elf -T olerance and N egative C ontrol of I mmune R esponses

Sakaguchi, S. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141122 · Cited by 3,293 · see citing works

An essential role for Scurfin in CD4+CD25+ T regulatory cells

Khattri, R., Cox, T., Yasayko, S.-A., & Ramsdell, F. (2003) · Nature Immunology · doi:10.1038/ni909 · Cited by 2,860 · see citing works

Immunol. Cell Biol.

Fitzgerald, M., Hayward, I. P., Thomas, A. C., Campbell, J. H., & CAMPBELL, G. R. (1995) · Cited by 2,552 · see citing works

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Zheng, W.-P., & Flavell, R. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80240-8 · Cited by 2,384 · see citing works

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4

Takahashi, T., Tagami, T., Yamazaki, S., Uede, T., Shimizu, J., Sakaguchi, N., Mak, T. W., & Sakaguchi, S. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.2.303 · Cited by 2,233 · see citing works

Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation

Read, S., Malmström, V., & Powrie, F. M. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.2.295 · Cited by 2,206 · see citing works

CD4+CD25+ suppressor T cells: more questions than answers

Shevach, E. M. (2002) · Nature reviews. Immunology · doi:10.1038/nri821 · Cited by 2,097 · see citing works

B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes

Salomon, B. L., Lenschow, D. J., Rhee, L., Ashourian, N., Singh, B., Sharpe, A. H., & Bluestone, J. A. (2000) · Immunity · doi:10.1016/s1074-7613(00)80195-8 · Cited by 2,058 · see citing works

CD4+CD25high Regulatory Cells in Human Peripheral Blood

Baecher‐Allan, C., Brown, J. A., Freeman, G. J., & Hafler, D. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.3.1245 · Cited by 1,857 · see citing works

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y., & Sakaguchi, S. (2002) · Nature Immunology · doi:10.1038/ni759 · Cited by 1,729 · see citing works

CD4+CD25+ Immunoregulatory T Cells

McHugh, R. S., Whitters, M. J., Piccirillo, C. A., Young, D. A., Shevach, E. M., Collins, M., & Byrne, M. C. (2002) · Immunity · doi:10.1016/s1074-7613(02)00280-7 · Cited by 1,395 · see citing works

Phenotypic and functional separation of memory and effector human CD8+ T cells

Hamann, D., Baars, P. A., Rep, M. H. G., Hooibrink, B., Kerkhof-Garde, S. R., Klein, M. R., & Lier, R. A. W. V. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.9.1407 · Cited by 1,366 · see citing works

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

Walker, M., Kasprowicz, D. J., Gersuk, V. H., Bénard, A., Landeghen, M. V., Buckner, J. H., & Ziegler, S. F. (2003) · Journal of Clinical Investigation · doi:10.1172/jci19441 · Cited by 1,242 · see citing works

Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo

Gavin, M. A., Clarke, S. R. M., Negrou, E., Gallegos, A. M., & Rudensky, A. Y. (2001) · Nature Immunology · doi:10.1038/ni743 · Cited by 640 · see citing works

Multiple immuno-regulatory defects in type-1 diabetes

Kukreja, A., Cost, G., Marker, J., Zhang, C., Sun, Z., Lin‐Su, K., Ten, S., Sanz, M. M., Exley, M. A., Wilson, B., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci13605 · Cited by 640 · see citing works

Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level

Roncador, G., Brown, P. J., Maestre, L., Hüe, S., Martinez-Torrecuadrada, J. L., Ling, K., Pratap, S., Toms, C., Fox, B. C., Cerundolo, V., et al. (2005) · European Journal of Immunology · doi:10.1002/eji.200526189 · Cited by 592 · see citing works

Multiple immuno-regulatory defects in type-1 diabetes

Kukreja, A., Cost, G., Marker, J., Zhang, C., Sun, Z., Lin‐Su, K., Ten, S., Sanz, M. M., Exley, M. A., Wilson, B., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0213605 · Cited by 567 · see citing works

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans

Morgan, M. E., van Bilsen, J. H. M., Bakker, A. M., Heemskerk, B., Schilham, M. W., Hartgers, F. C., Elferink, B. G., van der Zanden, L., de Vries, R. R. P., Huizinga, T. W. J., et al. (2004) · Human Immunology · doi:10.1016/j.humimm.2004.05.016 · Cited by 417 · see citing works

Quantification of regulatory T cells in patients with systemic lupus erythematosus

Crispín, J. C., Martínez, A. A., & Alcocer-Varela, J. C. (2003) · Journal of Autoimmunity · doi:10.1016/s0896-8411(03)00121-5 · Cited by 406 · see citing works

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

Stefanová, I., Dorfman, J. R., & Germain, R. N. (2002) · Nature · doi:10.1038/nature01146 · Cited by 389 · see citing works

Human CD4+CD25+ regulatory T cells

Baecher‐Allan, C. (2004) · Seminars in Immunology · doi:10.1016/j.smim.2003.12.005 · Cited by 385 · see citing works

Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia

Ruprecht, C. R., Gattorno, M., Ferlito, F., Gregorio, A., Martini, A., Lanzavecchia, A., & Sallusto, F. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050085 · Cited by 360 · see citing works

CD25brightCD4+regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

Cao, D., van Vollenhoven, R., Klareskog, L., Trollmo, C., & Malmström, V. (2004) · Arthritis Research & Therapy · doi:10.1186/ar1192 · Cited by 359 · see citing works

Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II

Kriegel, M. A., Lohmann, T., Gabler, C., Blank, N., Kalden, J. R., & Lorenz, H. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20032158 · Cited by 351 · see citing works

A peripheral circulating compartment of natural naive CD4 Tregs

Valmori, D., Merlo, A., Souleimanian, N. E., Hesdorffer, C. S., & Ayyoub, M. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23963 · Cited by 319 · see citing works

Induction of T helper type 1–like regulatory cells that express Foxp3 and protect against airway hyper-reactivity

Stock, P., Akbari, O., Berry, G. J., Freeman, G. J., DeKruyff, R. H., & Umetsu, D. T. (2004) · Nature Immunology · doi:10.1038/ni1122 · Cited by 313 · see citing works

Cord blood CD4+CD25+-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function

Godfrey, W. R., Spoden, D. J., Ge, Y. G., Baker, S. R., Liu, B., Levine, B. L., June, C. H., Blazar, B. R., & Porter, S. B. (2004) · Blood · doi:10.1182/blood-2004-06-2467 · Cited by 297 · see citing works

Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: implications for differential CD45 expression in T cell memory formation

Merkenschlager, M., Terry, L. A., Edwards, R. A., & Beverley, P. C. L. (1988) · European Journal of Immunology · doi:10.1002/eji.1830181102 · Cited by 278 · see citing works

CD4+CD25bright T Cells in Human Intestinal Lamina Propria as Regulatory Cells

Makita, S., Kanai∥, T., Oshima, S., Uraushihara, K., Totsuka, T., Sawada, T., Nakamura, T., Koganei, K., Fukushima, T., & Watanabe, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.5.3119 · Cited by 264 · see citing works

Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood

Wing, K., Ekmark, A., Karlsson, H., Rudin, A., & Suri‐Payer, E. (2002) · Immunology · doi:10.1046/j.1365-2567.2002.01412.x · Cited by 225 · see citing works

Characterization of the CD4+ T Cell Response to Epstein-Barr Virus during Primary and Persistent Infection

Amyes, E., Hatton, C., Montamat‐Sicotte, D., Gudgeon, N. H., Rickinson, A. B., McMichael, A. J., & Callan, M. F. C. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20022058 · Cited by 225 · see citing works

CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene

Takahata, Y., Nomura, A., Takada, H., Ohga, S., Furuno, K., Hikino, S., Nakayama, H., Sakaguchi, S., & Hara, T. (2004) · Experimental Hematology · doi:10.1016/j.exphem.2004.03.012 · Cited by 206 · see citing works

Cytokine Coexpression During Human Th1/Th2 Cell Differentiation: Direct Evidence for Coordinated Expression of Th2 Cytokines

Cousins, D. J., Lee, T. H., & Staynov, D. Z. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.5.2498 · Cited by 179 · see citing works

Antigen-pulsed CD8α+ Dendritic Cells Generate an Immune Response after Subcutaneous Injection without Homing to the Draining Lymph Node

Smith, A. L., & Groth, B. F. D. S. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.3.593 · Cited by 151 · see citing works

CD25+CD4+ regulatory T cells in patients with Kawasaki disease

Furuno, K., Yuge, T., Kusuhara, K., Takada, H., Nishio, H., Khajoee, V., Ohno, T., & Hara, T. (2004) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2004.05.048 · Cited by 115 · see citing works

CD4 T cell activation by myelin oligodendrocyte glycoprotein is suppressed by adult but not cord blood CD25+ T cells

Wing, K., Lindgren, S., Kollberg, G., Lundgren, A., Harris, R. A., Rudin, A., Lundin, S. B., & Suri‐Payer, E. (2003) · European Journal of Immunology · doi:10.1002/eji.200323701 · Cited by 97 · see citing works

Characterization of distinct stages during the differentiation of human CD69+CD3+ thymocytes and identification of thymic emigrants

Vanhecke, D., Leclercq, G., Plum, J. R., & Vandekerckhove, B. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.4.1862 · Cited by 92 · see citing works

CD4 + CD25 + T-Cell Production in Healthy Humans and in Patients with Thymic Hypoplasia

Sullivan, K. E., McDonald‐McGinn, D. M., & Zackai, E. H. (2002) · Clinical and Vaccine Immunology · doi:10.1128/cdli.9.5.1129-1131.2002 · Cited by 82 · see citing works

Kinetic of regulatory CD25high and activated CD134+ (OX40) T lymphocytes during acute and chronic graft‐versus‐host disease after allogeneic bone marrow transplantation

Sánchez, J., Casaño, J., Alvarez, M. A., Román‐Gómez, J., Martín, C., Martínez, F., Gomez, P., Serrano, J., Herrera, C., & Torres, A. (2004) · British Journal of Haematology · doi:10.1111/j.1365-2141.2004.05108.x · Cited by 74 · see citing works

Carboxyfluorescein diacetate succinimidyl ester and the virgin lymphocyte: A marriage made in heaven

Groth, B. F. D. S., Smith, A. L., Koh, W., Girgis, L., Cook, M., & Bertolino, P. (1999) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.1999.00871.x · Cited by 60 · see citing works

Following Antigen Challenge, T Cells Up-Regulate Cell Surface Expression of CD4 In Vitro and In Vivo

Ridgway, W. M., Fassò, M., & Fathman, C. G. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.2.714 · Cited by 59 · see citing works

An accessory role of TCRγ δ+ cells in the exacerbation of inflammatory bowel disease in TCRα mutant mice

Kawaguchi-Miyashita, M., Shimada, S., Kurosu, H., KATO-NAGAOKA, N., Matsuoka, Y., Ohwaki, M., Ishikawa, H., & Nanno, M. (2001) · European Journal of Immunology · doi:10.1002/1521-4141(200104)31:4 · Cited by 53 · see citing works

A study on CD45 isoform expression during T-cell development and selection events in the human thymus

Fukuhara, K., Okumura, M., Shiono, H., Inoue, M., Kadota, Y., Miyoshi, S., & Matsuda, H. (2002) · Human Immunology · doi:10.1016/s0198-8859(02)00379-8 · Cited by 46 · see citing works

T cell activation: in vivo veritas

Groth, B. F. D. S., Smith, A. L., & Higgins, C. A. (2004) · Immunology and Cell Biology · doi:10.1111/j.0818-9641.2004.01243.x · Cited by 42 · see citing works

Isolation of self antigen-reactive cells from inflamed islets of nonobese diabetic mice using CD4high expression as a marker.

Lejon, K., & Fathman, C. G. (1999) · PubMed · Cited by 29 · see citing works

Isolation of Self Antigen-Reactive Cells from Inflamed Islets of Nonobese Diabetic Mice Using CD4high Expression as a Marker

Kristina Lejon, C., & Fathman, G. C. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.10.5708 · Cited by 26 · see citing works

Untitled work

(2002) · doi:10.1002/1521-4141(200206)32:6

FOXP3+ regulatory T cells in the human immune system

Sakaguchi, S., Miyara, M., Costantino, C. M., & Hafler, D. A. (2010) · Nature reviews. Immunology · doi:10.1038/nri2785 · Cited by 2,443 · see citing works

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

Seddiki, N., Santner-Nanan, B., Martinson, J., Zaunders, J., Sasson, S., Landay, A., Solomon, M., Selby, W., Alexander, S. I., Nanan, R., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060468 · Cited by 1,512 · see citing works

Human T cell development, localization, and function throughout life

Kumar, B. V., Connors, T. J., & Farber, D. L. (2018) · Immunity · doi:10.1016/j.immuni.2018.01.007 · Cited by 1,257 · see citing works

Regulatory T Cells and Human Disease

Sakaguchi, S., Mikami, N., Wing, J. B., Tanaka, A., Ichiyama, K., & Ohkura, N. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042718-041717 · Cited by 1,132 · see citing works

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17–producing cells

Koenen, H. J. P. M., Smeets, R. L., Vink, P. M., van Rijssen, E., Boots, A. M. H., & Joosten, I. (2008) · Blood · doi:10.1182/blood-2008-01-133967 · Cited by 736 · see citing works

Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer

Wing, J. B., Tanaka, A., & Sakaguchi, S. (2019) · Immunity · doi:10.1016/j.immuni.2019.01.020 · Cited by 726 · see citing works

Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery

Ito, T., Hanabuchi, S., Wang, Y.-H., Park, W. R., Arima, K., Bover, L. C., Qin, F. X.-F., Gilliet, M. F., & Liu, Y. (2008) · Immunity · doi:10.1016/j.immuni.2008.03.018 · Cited by 541 · see citing works

Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion

Hoffmann, P., Eder, R., Boeld, T. J., Doser, K., Piseshka, B., Andreesen, R., & Edinger, M. (2006) · Blood · doi:10.1182/blood-2006-06-027409 · Cited by 405 · see citing works

Successful and Maladaptive T Cell Aging

Goronzy, J. J., & Weyand, C. M. (2017) · Immunity · doi:10.1016/j.immuni.2017.03.010 · Cited by 362 · see citing works

Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation

Hoffmann, P., Boeld, T. J., Eder, R., Huehn, J., Floess, S., Wieczorek, G., Olek, S., Dietmaier, W., Andreesen, R., & Edinger, M. (2009) · European Journal of Immunology · doi:10.1002/eji.200838904 · Cited by 356 · see citing works

Regulatory T cell memory

Rosenblum, M. D., Way, S. S., & Abbas, A. K. (2015) · Nature reviews. Immunology · doi:10.1038/nri.2015.1 · Cited by 346 · see citing works

Transient regulatory T-cells: A state attained by all activated human T-cells

Pillai, V., Ortega, S. B., Wang, C. K., & Karandikar, N. J. (2006) · Clinical Immunology · doi:10.1016/j.clim.2006.10.014 · Cited by 339 · see citing works

Mesenchymal cells recruit and regulate T regulatory cells

Ianni, M. D., Papa, B. D., Ioanni, M. D., Moretti, L., Bonifacio, E., Cecchini, D., Sportoletti, P., Falzetti, F., & Tabilio, A. (2008) · Experimental Hematology · doi:10.1016/j.exphem.2007.11.007 · Cited by 315 · see citing works

Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues

Thome, J. J. C., Bickham, K. L., Ohmura, Y., Kubota, M., Matsuoka, N., Gordon, C., Granot, T., Griesemer, A., Lerner, H., Kato, T., et al. (2016) · Nature Medicine · doi:10.1038/nm.4008 · Cited by 305 · see citing works

In vivo peripheral expansion of naive CD4+CD25highFoxP3+ regulatory T cells in patients with multiple myeloma

Beyer, M., Kochanek, M., Giese, T., Endl, E., Weihrauch, M. R., Knolle, P. A., Claßen, S., & Schultze, J. L. (2006) · Blood · doi:10.1182/blood-2005-09-3671 · Cited by 301 · see citing works

Natural Naive CD4+CD25+CD127low Regulatory T Cell (Treg) Development and Function Are Disturbed in Multiple Sclerosis Patients: Recovery of Memory Treg Homeostasis during Disease Progression

Venken, K., Hellings, N., Broekmans, T., Hensen, K., Rummens, J., & Stinissen, P. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.9.6411 · Cited by 261 · see citing works

Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells

Wang, R., Kozhaya, L., Mercer, F. K., Khaitan, A., Fujii, H., & Unutmaz, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901965106 · Cited by 252 · see citing works

Prevalence of Newly Generated Naive Regulatory T Cells (Treg) Is Critical for Treg Suppressive Function and Determines Treg Dysfunction in Multiple Sclerosis

Haas, J., Fritzsching, B., Trübswetter, P., Korporal, M., Milkova, L., Fritz, B., Vobis, D., Krammer, P. H., Suri‐Payer, E., & Wildemann, B. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.2.1322 · Cited by 250 · see citing works

Different Proliferative Potential and Migratory Characteristics of Human CD4+ Regulatory T Cells That Express either CD45RA or CD45RO

Booth, N. J., McQuaid, A. J., Sobande, T. O., Kissane, S., Agius, E., Jackson, S. E., Salmon, M., Francesco Falciani, B., Yong, K., Rustin, M. H. A., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903781 · Cited by 222 · see citing works

The dynamic co-evolution of memory and regulatory CD4+ T cells in the periphery

Akbar, A. N., Vukmanovic‐Stejic, M., Taams, L. S., & Macallan, D. C. (2007) · Nature reviews. Immunology · doi:10.1038/nri2037 · Cited by 215 · see citing works

Co‐expression of TNFR2 and CD25 identifies more of the functional CD4 + FOXP3 + regulatory T cells in human peripheral blood

Chen, X., Subleski, J. J., Hamano, R., Howard, O. M. Z., Wiltrout, R. H., & Oppenheim, J. J. (2010) · European Journal of Immunology · doi:10.1002/eji.200940022 · Cited by 209 · see citing works

Circulating Naïve and CD4+CD25high Regulatory T Cells in Patients With Autoimmune Pancreatitis

Miyoshi, H., Uchida, K., Taniguchi, T., Yazumi, S., Matsushita, M., Takaoka, M., & Okazaki, K. (2008) · Pancreas · doi:10.1097/mpa.0b013e3181577553 · Cited by 187 · see citing works

A mathematical model of tumor–immune interactions

Robertson‐Tessi, M., El-Kareh, A. W., & Goriely, A. (2011) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2011.10.027 · Cited by 187 · see citing works

High Levels of Human Antigen-Specific CD4+ T Cells in Peripheral Blood Revealed by Stimulated Coexpression of CD25 and CD134 (OX40)

Zaunders, J. J., Munier, C. M. L., Seddiki, N., Pett, S. L., Ip, S., Bailey, M., Xu, Y., Brown, K., Dyer, W. B., Kim, M., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803548 · Cited by 184 · see citing works

Human FoxP3+CD4+ regulatory T cells: their knowns and unknowns

Miyara, M., & Sakaguchi, S. (2011) · Immunology and Cell Biology · doi:10.1038/icb.2010.137 · Cited by 177 · see citing works

FOXP3 and the regulation of Treg/Th17 differentiation

Ziegler, S. F., & Buckner, J. H. (2009) · Microbes and Infection · doi:10.1016/j.micinf.2009.04.002 · Cited by 177 · see citing works

Role of mi R ‐155 in the regulation of lymphocyte immune function and disease

Seddiki, N., Brezar, V., Ruffin, N., Lévy, Y., & Swaminathan, S. (2013) · Immunology · doi:10.1111/imm.12227 · Cited by 172 · see citing works

Functional defect of circulating regulatory CD4+ T cells in patients with Wegener's granulomatosis in remission

Abdulahad, W. H., Stegeman, C. A., van der Geld, Y. M., der Meer, B. D., Limburg, P. C., & Kallenberg, C. G. M. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22692 · Cited by 173 · see citing works

Naive regulatory T cells: a novel subpopulation defined by resistance toward CD95L-mediated cell death

Fritzsching, B., Oberle, N., Pauly, E., Geffers, R., Buer, J., Pöschl, J. M. B., Krammer, P. H., Linderkamp, O., & Suri‐Payer, E. (2006) · Blood · doi:10.1182/blood-2006-02-005660 · Cited by 172 · see citing works

Phenotypical characterization of regulatory T cells in humans and rodents

Rodríguez-Perea, A. L., Arcia, D., Rueda, C. M., & Velilla, P. A. (2016) · Clinical & Experimental Immunology · doi:10.1111/cei.12804 · Cited by 167 · see citing works

Safety and T Cell Modulating Effects of High Dose Vitamin D3 Supplementation in Multiple Sclerosis

Smolders, J., Peelen, E., Thewissen, M. M., Tervaert, J. W. C., Menheere, P. P. C. A., Hupperts, R., & Damoiseaux, J. G. M. C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015235 · Cited by 166 · see citing works

Regulation of Trafficking Receptor Expression in Human Forkhead Box P3+ Regulatory T Cells

Lim, H. W., Broxmeyer, H. E., & Kim, C. H. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.2.840 · Cited by 164 · see citing works

Identification of a Regulatory T Cell Specific Cell Surface Molecule that Mediates Suppressive Signals and Induces Foxp3 Expression

Wang, R., Wan, Q., Kozhaya, L., Fujii, H., & Unutmaz, D. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002705 · Cited by 161 · see citing works

Regulatory T cells in homeostasis and disease: molecular mechanisms and therapeutic potential

Wang, L., Liang, Y., Zhao, C., Ma, P., Zeng, S., Ju, D., Zhao, M., Yu, M., & Shi, Y. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02326-4 · Cited by 177 · see citing works

Developmental Immunology and Role of Host Defenses in Fetal and Neonatal Susceptibility to Infection

Lewis, D. B., & Wilson, C. B. (2006) · Elsevier eBooks · doi:10.1016/b0-72-160537-0/50006-2 · Cited by 149 · see citing works

Disturbed regulatory T cell homeostasis in multiple sclerosis

Venken, K., Hellings, N., Liblau, R., & Stinissen, P. (2010) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2009.12.003 · Cited by 149 · see citing works

Pregnancy-associated diseases are characterized by the composition of the systemic regulatory T cell (Treg) pool with distinct subsets of Tregs

Steinborn, A., Schmitt, E., Kisielewicz, A., Rechenberg, S., Seissler, N., Mahnke, K., Schaier, M., Zeier, M. G., & Sohn, C. (2011) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2011.04493.x · Cited by 142 · see citing works

Genome-Wide Identification of Human FOXP3 Target Genes in Natural Regulatory T Cells

Sadlon, T. J., Wilkinson, B. G., Pederson, S., Brown, C. Y., Bresatz, S., Gargett, T., Melville, E. L., Peng, K., D’Andrea, R. J., Glonek, G. G., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000082 · Cited by 141 · see citing works

Molecular Mechanisms Controlling Foxp3 Expression in Health and Autoimmunity: From Epigenetic to Post-translational Regulation

Colamatteo, A., Carbone, F., Bruzzaniti, S., Galgani, M., Fusco, C., Maniscalco, G. T., Rella, F. D., de Candia, P., & Rosa, V. D. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.03136 · Cited by 139 · see citing works

The Tolerogenic Function of Regulatory T Cells in Pregnancy and Cancer

Jørgensen, N., Persson, G., & Hviid, T. V. F. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00911 · Cited by 133 · see citing works

Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

Leiding, J. W., Vogel, T. P., Santarlas, V. G. J., Mhaskar, R. S., Smith, M. R., Carisey, A. F., Vargas‐Hernández, A., Silva‐Carmona, M., Heeg, M., Rensing‐Ehl, A., et al. (2022) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2022.09.002 · Cited by 136 · see citing works

Cell-surface IL-7 receptor expression facilitates the purification of FOXP3+ regulatory T cells

Banham, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2006.10.002 · Cited by 131 · see citing works

Impaired regulatory function in circulating CD4+CD25highCD127low/− T cells in patients with myasthenia gravis

Thiruppathi, M., Rowin, J., Ganesh, B. B., Sheng, J. R., Prabhakar, B. S., & Meriggioli, M. N. (2012) · Clinical Immunology · doi:10.1016/j.clim.2012.09.012 · Cited by 128 · see citing works

Resolving the identity myth: Key markers of functional CD4+FoxP3+ regulatory T cells

Chen, X., & Oppenheim, J. J. (2011) · International Immunopharmacology · doi:10.1016/j.intimp.2011.05.018 · Cited by 127 · see citing works

Aging and human CD4+ regulatory T cells

Hwang, K.-A., Kim, H., & Kang, I. (2009) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2009.06.003 · Cited by 125 · see citing works

Central Role of CD45RA− Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance

Braza, F., Dugast, E., Panov, I., Paul, C., Vogt, K., Pallier, A., Chesneau, M., Baron, D., Guérif, P., Lei, H., et al. (2015) · Journal of the American Society of Nephrology · doi:10.1681/asn.2014050480 · Cited by 121 · see citing works

Glatiramer acetate improves regulatory T-cell function by expansion of naive CD4+CD25+FOXP3+CD31+ T-cells in patients with multiple sclerosis

Haas, J., Korporal, M., Balint, B., Fritzsching, B., Schwarz, A., & Wildemann, B. (2009) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2009.06.011 · Cited by 119 · see citing works

Are regulatory T-cells linked with aging?

Dejaco, C., Duftner, C., & Schirmer, M. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2006.01.008 · Cited by 118 · see citing works

Treg activation defect in type 1 diabetes: correction with TNFR2 agonism

Okubo, Y., Torrey, H., Butterworth, J., Zheng, H., & Faustman, D. L. (2016) · Clinical & Translational Immunology · doi:10.1038/cti.2015.43 · Cited by 111 · see citing works

Enhanced formation and survival of CD4+CD25hiFoxp3+T-cells in chronic lymphocytic leukemia

Jak, M., Jak, M., Mous, R., Remmerswaal, E. B. M., Spijker, R., Jaspers, A., Yagüe, A., Eldering, E., van Lier, R. A. W., & van Oers, M. H. J. (2009) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428190902803677 · Cited by 108 · see citing works

Dynamic Development of Homing Receptor Expression and Memory Cell Differentiation of Infant CD4+CD25high Regulatory T Cells

Grindebacke, H., Stenstad, H., Quiding‐Järbrink, M., Waldenström, J., Adlerberth, I., Wold, A. E., & Rudin, A. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901091 · Cited by 106 · see citing works

Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

Trzupek, D., Dunstan, M., Cutler, A. J., Lee, M., Godfrey, L., Jarvis, L., Rainbow, D. B., Aschenbrenner, D., Jones, J. L., Uhlig, H. H., et al. (2020) · Genome Medicine · doi:10.1186/s13073-020-00756-z · Cited by 105 · see citing works

Increased Frequency of Regulatory T Cells Accompanies Increased Immune Activation in Rectal Mucosae of HIV-Positive Noncontrollers

Shaw, J. M., Hunt, P. W., Critchfield, J. W., McConnell, D. H., Garcia, J. C., Pollard, R. B., Somsouk, M., Deeks, S. G., & Shacklett, B. L. (2011) · Journal of Virology · doi:10.1128/jvi.05608-11 · Cited by 104 · see citing works

Moving to tolerance: Clinical application of T regulatory cells

McMurchy, A. N., Bushell, A., Levings, M. K., & Wood, K. J. (2011) · Seminars in Immunology · doi:10.1016/j.smim.2011.04.001 · Cited by 101 · see citing works

Regulatory T cell defect in APECED patients is associated with loss of naive FOXP3+ precursors and impaired activated population

Laakso, S. M., Laurinolli, T.-T., Rossi, L. H., Lehtoviita, A., Sairanen, H. I., Perheentupa, J., Kekäläinen, E., & Arstila, T. P. (2010) · Journal of Autoimmunity · doi:10.1016/j.jaut.2010.07.008 · Cited by 99 · see citing works

The Impact of Aging on Regulatory T-Cells

Fessler, J., Ficjan, A., Duftner, C., & Dejaco, C. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00231 · Cited by 88 · see citing works

Naive Precursors of Human Regulatory T Cells Require FoxP3 for Suppression and Are Susceptible to HIV Infection

Antons, A. K., Wang, R., Oswald-Richter, K. A., Tseng, M., Arendt, C., Kalams, S. A., & Unutmaz, D. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.2.764 · Cited by 80 · see citing works

CD127low/- and FoxP3+ Expression Levels Characterize Different Regulatory T-Cell Populations in Human Peripheral Blood

Klein, S. M., Kretz, C. C., Krammer, P. H., & Kuhn, A. (2009) · Journal of Investigative Dermatology · doi:10.1038/jid.2009.313 · Cited by 79 · see citing works

Involvement of Inducible Costimulator- and Interleukin 10-Positive Regulatory T Cells in the Development of IgG4-Related Autoimmune Pancreatitis

Kusuda, T., Uchida, K., Miyoshi, H., Koyabu, M., Satoi, S., Takaoka, M., Shikata, N., Uemura, Y., & Okazaki, K. (2011) · Pancreas · doi:10.1097/mpa.0b013e31821fc796 · Cited by 78 · see citing works

DNA damage, metabolism and aging in pro-inflammatory T cells

Li, Y., Goronzy, J. J., & Weyand, C. M. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.10.027 · Cited by 79 · see citing works

FOXP3 Expression Is Upregulated in CD4+T Cells in Progressive HIV-1 Infection and Is a Marker of Disease Severity

Suchard, M. S., Mayne, E. S., Green, V. A., Shalekoff, S., Donninger, S. L., Stevens, W. S., Gray, C. M., & Tiemessen, C. T. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011762 · Cited by 76 · see citing works

The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer

Li, L., & Boussiotis, V. A. (2013) · Clinical Immunology · doi:10.1016/j.clim.2013.05.003 · Cited by 75 · see citing works

Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response?

Groth, B. F. D. S., & LANDAY, A. L. (2008) · AIDS · doi:10.1097/qad.0b013e3282f466da · Cited by 73 · see citing works

Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states

Macaubas, C., Nguyen, K. D., Deshpande, C., Phillips, C. I., Peck, A., Lee, T. C., Park, J. L., Sandborg, C. I., & Mellins, E. (2009) · Clinical Immunology · doi:10.1016/j.clim.2009.09.010 · Cited by 73 · see citing works

High frequency and proliferation of CD4+FOXP3+ Treg in HIV‐1‐infected patients with low CD4 counts

Bi, X., Suzuki, Y., Gatanaga, H., & Oka, S. (2008) · European Journal of Immunology · doi:10.1002/eji.200838667 · Cited by 72 · see citing works

Accelerated age-dependent transition of human regulatory T cells to effector memory phenotype

Santner-Nanan, B., Seddiki, N., Zhu, E., Quent, V., Kelleher, A., de St Groth, B. F., & Nanan, R. (2008) · International Immunology · doi:10.1093/intimm/dxm151 · Cited by 70 · see citing works

Mature T-Cell Leukemias Including T-Prolymphocytic Leukemia, Adult T-Cell Leukemia/Lymphoma, and Sézary Syndrome

Foucar, K. K. (2007) · American Journal of Clinical Pathology · doi:10.1309/k342-1w28-3805-633g · Cited by 70 · see citing works

Hepatocellular carcinoma cell supernatants increase expansion and function of CD4+CD25+ regulatory T cells

Cao, M., Cabrera, R., Xu, Y., Firpi, R. J., Zhu, H., Liu, C., & Nelson, D. R. (2007) · Laboratory Investigation · doi:10.1038/labinvest.3700540 · Cited by 69 · see citing works

FOXP3+ Tregs: heterogeneous phenotypes and conflicting impacts on survival outcomes in patients with colorectal cancer

Zhuo, C., Xu, Y., Ying, M., Li, Q., Huang, L., Li, D., Cai, S., & Li, B. (2015) · Immunologic Research · doi:10.1007/s12026-014-8616-y · Cited by 69 · see citing works

TGF-β–dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis

Wang, H., Peters, T., Sindrilaru, A., Keß, D., Oreshkova, T., Yu, X., Seier, A. M., Schreiber, H. A., Wlaschek, M., Blakytny, R., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34916 · Cited by 69 · see citing works

Multiple sclerosis patients have reduced resting and increased activated CD4+CD25+FOXP3+T regulatory cells

Verma, N. D., Lam, A. D., Chiu, C., Tran, G. T., Hall, B. M., & Hodgkinson, S. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-88448-5 · Cited by 68 · see citing works

Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis

Fessler, J., Raicht, A., Husic, R., Ficjan, A., Schwarz, C., Duftner, C., Schwinger, W., Graninger, W. B., Stradner, M. H., & Dejaco, C. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00300 · Cited by 66 · see citing works

CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation

Atanackovic, D., Cao, Y., Luetkens, T., Panse, J., Faltz, C., Arfsten, J., Bartels, K., Wolschke, C., EIERMANN, T. H., Zander, A. R., et al. (2008) · Haematologica · doi:10.3324/haematol.11897 · Cited by 64 · see citing works

Roles of Tregs in development of hepatocellular carcinoma: A meta-analysis

Zhao, H. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i24.7971 · Cited by 64 · see citing works

Promoting transplantation tolerance; adoptive regulatory T cell therapy

Safinia, N., Leech, J. M., Hernández-Fuentes, M. P., Lechler, R. I., & Lombardi, G. (2012) · Clinical & Experimental Immunology · doi:10.1111/cei.12052 · Cited by 62 · see citing works

CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells

Liu, T., Soong, L., Liu, G., König, R., & Chopra, A. K. (2009) · Biology Direct · doi:10.1186/1745-6150-4-40 · Cited by 63 · see citing works

Enhanced frequency and potential mechanism of B regulatory cells in patients with lung cancer

Zhou, J.-B., Min, Z., Zhang, D., Wang, W., Marincola, F., & Wang, X.-D. (2014) · Journal of Translational Medicine · doi:10.1186/s12967-014-0304-0 · Cited by 59 · see citing works

Dual Mechanism of Impairment of Interleukin-7 (IL-7) Responses in Human Immunodeficiency Virus Infection: Decreased IL-7 Binding and Abnormal Activation of the JAK/STAT5 Pathway

Juffroy, O., Bugault, F., Lambotte, O., Landires, I., Viard, J., Niel, L., Fontanet, A. L., Delfraissy, J., Thèze, J., & Chakrabarti, L. A. (2009) · Journal of Virology · doi:10.1128/jvi.01475-09 · Cited by 61 · see citing works

Post-chemotherapy T-cell recovery is a marker of improved survival in patients with advanced thoracic malignancies

McCoy, M. J., Lake, R., der Most, R. G. V., Dick, I. M., & Nowak, A. K. (2012) · British Journal of Cancer · doi:10.1038/bjc.2012.362 · Cited by 60 · see citing works

Essential and synergistic roles of IL1 and IL6 in human Th17 differentiation directed by TLR ligand-activated dendritic cells

Benwell, R. K., & Lee, D. R. (2009) · Clinical Immunology · doi:10.1016/j.clim.2009.09.013 · Cited by 60 · see citing works

Isolation strategies of regulatory T cells for clinical trials: Phenotype, function, stability, and expansion capacity

Ukena, S. N., Hoepting, M., Velaga, S., Ivanyi, P., Grosse, J., Baron, U., Ganser, A., & Franzke, A. (2011) · Experimental Hematology · doi:10.1016/j.exphem.2011.08.010 · Cited by 59 · see citing works

DRhigh+CD45RA−-Tregs Potentially Affect the Suppressive Activity of the Total Treg Pool in Renal Transplant Patients

Schaier, M., Seissler, N., Schmitt, E., Meuer, S. C., Hug, F., Zeier, M. G., & Steinborn, A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034208 · Cited by 58 · see citing works

Regulatory T Cell Dysfunction in Autoimmune Diseases

Honing, D. Y., Luiten, R. M., & Matos, T. R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137171 · Cited by 58 · see citing works

Monotherapy rapamycin allows an increase of CD4+ CD25bright+ FoxP3+T cells in renal recipients

Hendrikx, T. K., Velthuis, J. H. L., Klepper, M., van Gurp, E., Geel, A., Schoordijk, W., Baan, C. C., & Weimar, W. (2009) · Transplant International · doi:10.1111/j.1432-2277.2009.00890.x · Cited by 57 · see citing works

Antibody Therapies for Acute Myeloid Leukemia: Unconjugated, Toxin-Conjugated, Radio-Conjugated and Multivalent Formats

Williams, B. A., Law, A., Hunyadkürti, J., Désilets, S., Leyton, J. V., & Keating, A. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8081261 · Cited by 57 · see citing works

Developmental changes of FOXP3-expressing CD4+CD25+ regulatory T cells and their impairment in patients with FOXP3 gene mutations

Fuchizawa, T., Adachi, Y., Ito, Y., Higashiyama, H., Kanegane, H., Futatani, T., Kobayashi, I., Kamachi, Y., Sakamoto, T., Tsuge, I., et al. (2007) · Clinical Immunology · doi:10.1016/j.clim.2007.08.004 · Cited by 56 · see citing works

Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers

Oparaugo, N. C., Ouyang, K., Nguyen, N. P. N., Nelson, A. M., & Agak, G. W. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021527 · Cited by 60 · see citing works

The micro RNA ‐9/ B ‐lymphocyte‐induced maturation protein‐1/ IL ‐2 axis is differentially regulated in progressive HIV infection

Seddiki, N., Phetsouphanh, C., Swaminathan, S., Xu, Y., Rao, S., Li, J., Sutcliffe, E. L., Denyer, G. S., Finlayson, R. J., Gelgor, L., et al. (2012) · European Journal of Immunology · doi:10.1002/eji.201242695 · Cited by 55 · see citing works

CD4+FOXP3+ Regulatory T-Cell Subsets in Human Immunodeficiency Virus Infection

Simonetta, F., & Bourgeois, C. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00215 · Cited by 55 · see citing works

Impaired Thymic Export and Increased Apoptosis Account for Regulatory T Cell Defects in Patients with Non-ST Segment Elevation Acute Coronary Syndrome

Zhang, W., Wang, J., Shu, Y., Tang, T., Zhu, Z., Xia, N., Nie, S., Liu, J., Zhou, S., Li, J., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.382978 · Cited by 54 · see citing works

Neonatal Cord Blood Subsets and Cytokine Response to Bacterial Antigens

Peoples, J., Cheung, S., Nesin, M., Lin, H., Tatad, A. M. F., Hoang, D., Perlman, J. M., & Cunningham–Rundles, S. (2009) · American Journal of Perinatology · doi:10.1055/s-0029-1220788 · Cited by 52 · see citing works

Regulatory T-cell therapy approaches

McCallion, O., Bilici, M., Hester, J., & Issa, F. (2022) · Clinical & Experimental Immunology · doi:10.1093/cei/uxac078 · Cited by 50 · see citing works

Regulatory CAR-T cells in autoimmune diseases: Progress and current challenges

Riët, T., & Chmielewski, M. M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.934343 · Cited by 54 · see citing works

Human Natural Regulatory T Cell Development, Suppressive Function, and Postthymic Maturation in a Humanized Mouse Model

Onoe, T., Kalscheuer, H., Danzl, N. M., Chittenden, M., Zhao, G., Yang, Y., & Sykes, M. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1100394 · Cited by 51 · see citing works

Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ Tregs

Tosello, V., Odunsi, K. O., Souleimanian, N. E., Lele, S., Shrikant, P. A., Old, L. J., Valmori, D., & Ayyoub, M. (2008) · Clinical Immunology · doi:10.1016/j.clim.2007.11.008 · Cited by 51 · see citing works

Comparative Study of Regulatory T Cell Function of Human CD25+ CD4+ T Cells from Thymocytes, Cord Blood, and Adult Peripheral Blood

Fujimaki, W., Takahashi, N., Ohnuma, K., Nagatsu, M., Kurosawa, H., Yoshida, S., Dang, N. H., Uchiyama, T., & Morimoto, C. (2008) · Clinical and Developmental Immunology · doi:10.1155/2008/305859 · Cited by 51 · see citing works

Current status of type 1 (IgG4-related) autoimmune pancreatitis

Uchida, K., & Okazaki, K. (2022) · Journal of Gastroenterology · doi:10.1007/s00535-022-01891-7 · Cited by 49 · see citing works

Differentiation of IL-17–Producing Effector and Regulatory Human T Cells from Lineage-Committed Naive Precursors

Mercer, F. K., Khaitan, A., Kozhaya, L., Aberg, J. A., & Unutmaz, D. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1302936 · Cited by 48 · see citing works

Increased levels of regulatory T cells (Tregs) in human immunodeficiency virus-infected patients after 5 years of highly active anti-retroviral therapy may be due to increased thymic production of naive Tregs

Kolte, L., Gaardbo, J. C., Skogstrand, K., Ryder, L. P., Ersbøll, A. K., & Nielsen, S. D. (2008) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2008.03803.x · Cited by 47 · see citing works

Differentiation of human thymic regulatory T cells at the double positive stage

Nunes‐Cabaço, H., Caramalho, Í., Sepúlveda, N., & Sousa, A. E. (2011) · European Journal of Immunology · doi:10.1002/eji.201141614 · Cited by 47 · see citing works

Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood

Wing, K., Ekmark, A., Karlsson, H., Rudin, A., & Suri‐Payer, E. (2002) · Immunology · doi:10.1046/j.1365-2567.2002.01412.x · Cited by 225 · see citing works

CD4+CD25+FOXP3+ regulatory T cells from human thymus and cord blood suppress antigen‐specific T cell responses

Wing, K., Larsson, P., Sandström, K., Lundin, S. B., Suri‐Payer, E., & Rudin, A. (2005) · Immunology · doi:10.1111/j.1365-2567.2005.02186.x · Cited by 104 · see citing works

The comparison of CD4~+ CD25~+ regulatory T cells in isolation and functional characterization between cord blood and adult peripheral blood

Gao, M. (2011) · Journal of Taishan Medical College

Human CD4+CD25+ cells: a naturally occurring population of regulatory T cells

Ng, W., Duggan, P. J., Ponchel, F., Matarese, G., Lombardi, G., Edwards, A. D., Isaacs, J. D., & Lechler, R. I. (2001) · Blood · doi:10.1182/blood.v98.9.2736 · Cited by 606 · see citing works

Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood

Dieckmann, D., Ploettner, H., Berchtold, S., Berger, T. G., & Schuler, G. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.11.1303 · Cited by 1,140 · see citing works