Rationale and study design for a randomised controlled trial to reduce sedentary time in adults at risk of type 2 diabetes mellitus: project stand (Sedentary Time ANd diabetes)
Open accessAbstract
BACKGROUND: The rising prevalence of Type 2 Diabetes Mellitus (T2DM) is a major public health problem. There is an urgent need for effective lifestyle interventions to prevent the development of T2DM. Sedentary behaviour (sitting time) has recently been identified as a risk factor for diabetes, often independent of the time spent in moderate-to-vigorous physical activity. Project STAND (Sedentary Time ANd Diabetes) is a study which aims to reduce sedentary behaviour in younger adults at high risk of T2DM. METHODS/DESIGN: A reduction in sedentary time is targeted using theory driven group structured education. The STAND programme is subject to piloting and process evaluation in line with the MRC framework for complex interventions. Participants are encouraged to self-monitor and self-regulate their behaviour. The intervention is being assessed in a randomised controlled trial with 12 month follow up. Inclusion criteria are a) aged 18-40 years with a BMI in the obese range; b) 18-40 years with a BMI in the overweight range plus an additional risk factor for T2DM. Participants are randomised to the intervention (n = 89) or control (n = 89) arm. The primary outcome is a reduction in sedentary behaviour at 12 months as measured by an accelerometer (count < 100/min). Secondary outcomes include physical activity, sitting/lying time using the ActivPAL posture monitor, fasting and 2 h oral glucose tolerance test, lipids, inflammatory biomarkers, body weight, waist circumference, blood pressure, illness perceptions, and efficacy beliefs for behaviour change. CONCLUSIONS: This is the first UK trial to address sedentary behaviour change in a population of younger adults at risk of T2DM. The results will provide a platform for the development of a range of future multidisciplinary interventions in this rapidly expanding high-risk population. TRIAL REGISTRATION: Current controlled trials ISRCTN08434554, MRC project 91409.
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The Gruve monitor has been shown to be accurate in measuring sedentary and walking activities when compared with a gold standard system (r2=0.98) and is recommended for use in interventions aiming to reduce sedentary behavior.
“The Gruve monitor has been shown to be accurate in measuring sedentary and walking activities when compared with a gold standard system (r2=0.98) [86] and is recommended for use in interventions aiming to reduce sedentary behavior [87].”
From Consumer-based wearable activity trackers increase physical activity participation: systematic review and meta-analysis (2019) · cites this paper as [87]
In Methods > Phase 2: Curriculum development (page not provided), the authors say pilot feedback led them to consider Gruve the most appropriate self-monitoring device for their sedentary-time intervention. That supports its use in this study, but not a general recommendation for all interventions aiming to reduce sedentary behavior. The accuracy claim is attached to a different citation [86] and is not assessed here. (LLM, conf=0.85)
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- Authors
- Wilmot, E. G., Davies, M. J., Edwardson, C. L., Gorely, T., Khunti, K., Nimmo, M., Yates, T., & Biddle, S. J.
- Affiliations
- University of Leicester (GB)
- Loughborough University (GB)
- Corresponding author
- Biddle, Stuart JH
- ORCID
- Venue
- BMC Public Health
- Published
- 2011-12
- Volume
- 11
- Issue
- 1
- Pages
- 908-908
- ISSN
- 1471-2458 (ISSN-L)
- PMC
- PMC3262766
- OpenAlex
- W1970524942
- Cited by
- 42
- References
- 43
- Citations by year
- 2021: 3 · 2020: 4 · 2019: 3 · 2018: 5 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 3 · 2013: 9 · 2012: 4
- FWCI
- 3.49
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Public Health (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- University of Southern Queensland ePrints (University of Southern Queensland) (acceptedVersion)
- Victoria University Research Repository (Victoria University) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Minerva Access (University of Melbourne) (submittedVersion, cc-by)
- Leicester Research Archive (University of Leicester) (submittedVersion, cc-by)
- Leicester Research Archive (University of Leicester) (submittedVersion, other-oa)
- Funders
- Medical Research Council (91409)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- sedentary behavior, type 2 diabetes prevention, young adults, obesity, self-monitoring, physical activity, sitting time, glucose tolerance, inflammatory markers, lifestyle intervention, complex interventions
- MeSH terms
- Adolescent, Adult, Diabetes Mellitus, Type 2, United Kingdom, Health Promotion, Humans, Interviews as Topic, Research Design, Risk Reduction Behavior, Young Adult, Sedentary Behavior
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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