Efficacy of light therapy for perinatal depression: a review
Open accessAbstract
Perinatal depression is an important public health problem affecting 10% to 20% of childbearing women. Perinatal depression is associated with significant morbidity, and has enormous consequences for the wellbeing of the mother and child. During the perinatal period, treatment of depression, which could affect the mother and child during pregnancy and lactation, poses a complex problem for both mother and clinician. Bright light therapy may be an attractive treatment for perinatal depression because it is low cost, home-based, and has a much lower side effect profile than pharmacotherapy. The antidepressant effects of bright light are well established, and there are several rationales for expecting that bright light might also be efficacious for perinatal depression. This review describes these rationales, summarizes the available evidence on the efficacy of bright light therapy for perinatal depression, and discusses future directions for investigation of bright light therapy as a treatment for perinatal depression.
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Only a few studies have used bright light therapy in either antenatal or postnatal depression, with overall promising but partly divergent findings.
“However, only a few studies have used BLT in either antenatal or postnatal depression, with overall promising but partly divergent findings. 4 , 5”
From Sustained remission from perinatal depression after bright light therapy: A pilot randomised, placebo‐controlled trial (2022) · cites this paper as [4]
The study adopted a low-intensity control light, likely further differentiating the neurobiological effects of the experimental light interventions.
“Moreover, in contrast to previous studies, which used placebo lights in a range between 70 and 600 lux, 4 , 5 , 14 we adopted a low‐intensity control light, likely further differentiating the neurobiological effects of the experimental light interventions.”
From Sustained remission from perinatal depression after bright light therapy: A pilot randomised, placebo‐controlled trial (2022) · cites this paper as [4]
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Cited by
Sorted by citations
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“, 2011) in two trials for postnatal depression (Crowley and Youngstedt, 2012).”
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Depressive disorders: Processes leading to neurogeneration and potential novel treatments
Brown, G. M., McIntyre, R. S., Rosenblat, J. D., & Hardeland, R. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.04.023 · Cited by 44 · see citing works
“Light therapy as a nonpharmaceutical treatment has been recommended and is being tested as a method avoiding any pharmacological load during pregnancy and in perinatal depression(Bais et al., 2016; Crowley and Youngstedt, 2012).”
MethodLight therapy: is it safe for the eyes?
Brouwer, A., Nguyen, H. ‐., Snoek, F. J., van Raalte, D. H., Beekman, A. T. F., Moll, A. C., & Bremmer, M. A. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12785 · Cited by 40 · see citing works
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Donmez, M., Yorguner, N., Kora, K., & Topcuoglu, V. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.02.027 · Cited by 34 · see citing works
Perinatal Depression and the Role of Synaptic Plasticity in Its Pathogenesis and Treatment
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“Additional benefits include its ability to alleviate fatigue and insomnia, modulate in estrogen levels, regulate serotonergic metabolism, and resynchronize the circadian system [77].”
Background
- Authors
- Crowley, S. K., & Youngstedt, S. D.
- Affiliations
- University of South Carolina (US)
- Corresponding author
- Crowley, Shannon K
- Venue
- Journal of Physiological Anthropology
- Published
- 2012-06-06
- Volume
- 31
- Issue
- 1
- Pages
- 15-15
- ISSN
- 1880-6791 (ISSN-L)
- 1880-6805
- PMC
- PMC3518242
- OpenAlex
- W2125086533
- Cited by
- 55
- References
- 0
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 5 · 2019: 5 · 2018: 2 · 2017: 5 · 2016: 4 · 2015: 8 · 2014: 3 · 2013: 4 · 2012: 1
- FWCI
- 0.80
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of PHYSIOLOGICAL ANTHROPOLOGY (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- National Institutes of Health (NIH-R01, HL095799)
- National Heart, Lung, and Blood Institute (R01HL095799)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- perinatal depression, bright light therapy, pregnancy, lactation, non-pharmacological treatment, maternal mental health
- MeSH terms
- Depressive Disorder, Female, Humans, Phototherapy, Pregnancy, Pregnancy Complications, Depression, Postpartum, Peripartum Period
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