Promise and pitfalls of the Immunochip

Finding the missing heritability of complex diseases

Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., McCarthy, M. I., Ramos, E. M., Cardon, L. R., Chakravarti, A., et al. (2009) · Nature · doi:10.1038/nature08494 · Cited by 8,336 · see citing works

Common SNPs explain a large proportion of the heritability for human height

Yang, J., Benyamin, B., McEvoy, B. P., Gordon, S., Henders, A. K., Nyholt, D. R., Madden, P. A., Heath, A. C., Martin, N. G., Montgomery, G. W., et al. (2010) · Nature Genetics · doi:10.1038/ng.608 · Cited by 4,446 · see citing works

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Lango Allen, H., Estrada, K., Lettre, G., Berndt, S. I., Weedon, M. N., Rivadeneira, F., Willer, C. J., Jackson, A. U., Vedantam, S., Raychaudhuri, S., et al. (2010) · Nature · doi:10.1038/nature09410 · Cited by 1,945 · see citing works

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

The Wellcome Trust Case Control Consortium (2010) · Nature · doi:10.1038/nature08979 · Cited by 807 · see citing works

DNA methylation profiles in monozygotic and dizygotic twins

Kaminsky, Z. A., Tang, T., Wang, S.-C., Ptak, C., Oh, G., Wong, A. H. C., Feldcamp, L. A., Virtanen, C., Halfvarson, J., Tysk, C., et al. (2009) · Nature Genetics · doi:10.1038/ng.286 · Cited by 662 · see citing works

Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies

Keating, B. J., Tischfield, S. E., Murray, S. S., Bhangale, T., Price, T. S., Glessner, J., Galver, L., Barrett, J. C., Grant, S. F. A., Farlow, D., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003583 · Cited by 370 · see citing works

Epigenetic Inheritance and the Missing Heritability Problem

Slatkin, M. (2009) · Genetics · doi:10.1534/genetics.109.102798 · Cited by 337 · cited 1× · see citing works

A Statistical Method for Predicting Classical HLA Alleles from SNP Data

Leslie, S., Donnelly, P., & McVean, G. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.09.001 · Cited by 173 · see citing works

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

The International IBD Genetics Consortium (IIBDGC), Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., McGovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., et al. (2012) · Nature · doi:10.1038/nature11582 · Cited by 4,722 · see citing works

10 Years of GWAS Discovery: Biology, Function, and Translation

Visscher, P. M., Wray, N. R., Zhang, Q., Sklar, P., McCarthy, M. I., Brown, M. A., & Yang, J. (2017) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2017.06.005 · Cited by 3,719 · see citing works

Benefits and limitations of genome-wide association studies

Tam, V., Patel, N. K., Turcotte, M., Bossé, Y., Paré, G., & Meyre, D. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0127-1 · Cited by 2,092 · see citing works

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

International Multiple Sclerosis Genetics Consortium (IMSGC) (2013) · Nature Genetics · doi:10.1038/ng.2770 · Cited by 1,386 · see citing works

Pleiotropy in complex traits: challenges and strategies

Solovieff, N., Cotsapas, C., Lee, P. H., Purcell, S. M., & Smoller, J. W. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3461 · Cited by 1,085 · see citing works

Rare-Variant Association Analysis: Study Designs and Statistical Tests

Lee, S., Abecasis, G. R., Boehnke, M., & Lin, X. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2014.06.009 · Cited by 1,042 · see citing works

The UK10K project identifies rare variants in health and disease

The UK10K Consortium, Writing group, Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R. B., Xu, C., et al. (2015) · Nature · doi:10.1038/nature14962 · Cited by 1,040 · see citing works

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Collaborative Association Study of Psoriasis (CASP), Tsoi, L. C., Genetic Analysis of Psoriasis Consortium, Psoriasis Association Genetics Extension, Wellcome Trust Case Control Consortium 2, Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., et al. (2012) · Nature Genetics · doi:10.1038/ng.2467 · Cited by 1,024 · see citing works

The druggable genome and support for target identification and validation in drug development

Finan, C., Gaulton, A., Krüger, F. A., Lumbers, R. T., Shah, T., Engmann, J., Galver, L., Kelley, R., Karlsson, A., Santos, R., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aag1166 · Cited by 1,011 · see citing works

Genetically Distinct Subsets within ANCA-Associated Vasculitis

Lyons, P., Rayner, T. F., Trivedi, S., Holle, J. U., Watts, R. A., Jayne, D. R. W., Baslund, B., Brenchley, P. E., Bruchfeld, A. N., Chaudhry, A., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1108735 · Cited by 1,007 · see citing works

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

Cortés, A., Hadler, J. S., Robinson, P. C., Leo, P., Cremin, K., Pryce, K., Harris, J., Bradbury, L. A., Kenna, T., Yang, J., et al. (2013) · Nature Genetics · doi:10.1038/ng.2667 · Cited by 855 · see citing works

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

Trynka, G., PreventCD Study Group, Hunt, K. A., Bockett, N. A., Romanos, J., Mistry, V., Szperl, A., Bakker, S. F., Bardella, M. T., Bhaw, L., et al. (2011) · Nature Genetics · doi:10.1038/ng.998 · Cited by 825 · see citing works

The MHC locus and genetic susceptibility to autoimmune and infectious diseases

Matzaraki, V., Kumar, V., Wijmenga, C., & Zhernakova, A. (2017) · Genome biology · doi:10.1186/s13059-017-1207-1 · Cited by 566 · see citing works

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

for UK Primary Sjögren's Syndrome Registry, Lessard, C. J., Li, H., Adrianto, I., Ice, J. A., Rasmussen, A., Grundahl, K. M., Kelly, J. A., Dozmorov, M. G., Miceli‐Richard, C., et al. (2013) · Nature Genetics · doi:10.1038/ng.2792 · Cited by 531 · see citing works

Genetic insights into common pathways and complex relationships among immune-mediated diseases

Parkes, M., Cortés, A., van Heel, D. A., & Brown, M. A. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3502 · Cited by 522 · see citing works

Quality control and conduct of genome-wide association meta-analyses

Winkler, T. W., Day, F. R., Croteau‐Chonka, D. C., Wood, A. R., Locke, A. E., Mägi, R., Ferreira, T., Fall, T., Graff, M., Justice, A. E., et al. (2014) · Nature Protocols · doi:10.1038/nprot.2014.071 · Cited by 502 · see citing works

The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits

Voight, B. F., Kang, H. M., Ding, J., Palmer, C. D., Sidore, C., Chines, P. S., Burtt, N. P., Fuchsberger, C., Li, Y., Erdmann, J., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002793 · Cited by 464 · see citing works

Open Targets Platform: new developments and updates two years on

Carvalho‐Silva, D., Pierleoni, A., Pignatelli, M., Ong, C. K., Fumis, L., Karamanis, N., Carmona, M., Faulconbridge, A., Hercules, A., McAuley, E., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky1133 · Cited by 449 · see citing works

Genetics of Inflammatory Bowel Diseases

McGovern, D. P. B., Kugathasan, S., & Cho, J. H. (2015) · Gastroenterology · doi:10.1053/j.gastro.2015.08.001 · Cited by 428 · see citing works

The immunogenetics of multiple sclerosis: A comprehensive review

Hollenbach, J. A., & Oksenberg, J. R. (2015) · Journal of Autoimmunity · doi:10.1016/j.jaut.2015.06.010 · Cited by 423 · see citing works

Transancestral mapping and genetic load in systemic lupus erythematosus

Langefeld, C. D., Ainsworth, H. C., Graham, D. S. C., Kelly, J. A., Comeau, M. E., Marion, M. C., Howard, T. D., Ramos, P. S., Croker, J. A., Morris, D. L., et al. (2017) · Nature Communications · doi:10.1038/ncomms16021 · Cited by 421 · see citing works

Complex host genetics influence the microbiome in inflammatory bowel disease

Knights, D., Silverberg, M. S., Weersma, R. K., Gevers, D., Dijkstra, G., Huang, H., Tyler, A. D., van Sommeren, S., Imhann, F., Stempak, J. M., et al. (2014) · Genome Medicine · doi:10.1186/s13073-014-0107-1 · Cited by 418 · see citing works

Multiple sclerosis genetics

Sawcer, S. J., Franklin, R. J. M., & Ban, M. (2014) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70041-9 · Cited by 404 · see citing works

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

Boston Children's JIA Registry, Hinks, A., British Society of Paediatric and Adolescent Rheumatology (BSPAR) Study Group, (CAPS), C. A. P. S., (CHARMS), C. A. R. T. M. S., German Society for Pediatric Rheumatology (GKJR), Study, J. G. E., NIAMS JIA Genetic Registry, Study, T., Cobb, J. E., et al. (2013) · Nature Genetics · doi:10.1038/ng.2614 · Cited by 397 · see citing works

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

The UK-PSCSC Consortium, Liu, J. Z., The International IBD Genetics Consortium, The International PSC Study Group, Hov, J. R., Folseraas, T., Ellinghaus, E., Rushbrook, S. M., Doncheva, N. T., Andreassen, O. A., et al. (2013) · Nature Genetics · doi:10.1038/ng.2616 · Cited by 391 · see citing works

Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.

Swerdlow, D. I., Kuchenbaecker, K. B., Shah, S., Sofat, R., Holmes, M. V., White, J., Mindell, J. S., Kivimaki, M., Brunner, E. J., Whittaker, J. C., et al. (2016) · International Journal of Epidemiology · doi:10.1093/ije/dyw088 · Cited by 387 · see citing works

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

Tsoi, L. C., Stuart, P. E., Tian, C., Gudjonsson, J. E., Das, S., Zawistowski, M., Ellinghaus, E., Barker, J. N., Chandran, V., Dand, N., et al. (2017) · Nature Communications · doi:10.1038/ncomms15382 · Cited by 384 · see citing works

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

Amos, C. I., Dennis, J., Wang, Z., Byun, J., Schumacher, F. R., Gayther, S. A., Casey, G., Hunter, D. J., Sellers, T. A., Gruber, S. B., et al. (2016) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-16-0106 · Cited by 337 · see citing works

Cytomegalovirus infection enhances the immune response to influenza

Furman, D., Jojic, V., Sharma, S., Shen-Orr, S. S., L. Angel, C. J., Onengut-Gumuscu, S., Kidd, B. A., Maecker, H. T., Concannon, P., Dekker, C. L., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa2293 · Cited by 332 · see citing works

Genetic Variants Regulating Immune Cell Levels in Health and Disease

Orrù, V., Steri, M., Sole, G., Sidore, C., Virdis, F., Dei, M., Lai, S., Żołędziewska, M., Busonero, F., Mulas, A., et al. (2013) · Cell · doi:10.1016/j.cell.2013.08.041 · Cited by 330 · see citing works

Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

Ferreira, R. C., Freitag, D. F., Cutler, A. J., Howson, J. M. M., Rainbow, D. B., Smyth, D. J., Kaptoge, S., Clarke, P., Boreham, C., Coulson, R. M., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003444 · Cited by 316 · see citing works

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

Cortés, A., Pulit, S. L., Leo, P. J., Pointon, J. J., Robinson, P. C., Weisman, M. H., Ward, M. M., Gensler, L. S., Zhou, X., Garchon, H., et al. (2015) · Nature Communications · doi:10.1038/ncomms8146 · Cited by 303 · see citing works

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

Robertson, C. C., Inshaw, J. R. J., Onengut-Gumuscu, S., Chen, W.-M., Santa Cruz, D. F., Yang, H., Cutler, A. J., Crouch, D. J. M., Farber, E., Bridges, S. L., et al. (2021) · Nature Genetics · doi:10.1038/s41588-021-00880-5 · Cited by 302 · see citing works

Genetics of ankylosing spondylitis—insights into pathogenesis

Brown, M. A., Kenna, T., & Wordsworth, B. P. (2015) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2015.133 · Cited by 291 · see citing works

Genetics and Pathogenesis of Inflammatory Bowel Disease

Liu, T.-C., & Stappenbeck, T. S. (2016) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-012615-044152 · Cited by 289 · see citing works

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

The UK Primary Biliary Cirrhosis (PBC) Consortium, Liu, J. Z., The Wellcome Trust Case Control Consortium 3, Almarri, M. A., Gaffney, D. J., Mells, G. F., Jostins, L., Cordell, H. J., Ducker, S. J., Day, D. B., et al. (2012) · Nature Genetics · doi:10.1038/ng.2395 · Cited by 274 · see citing works

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

Li, Y. R., Li, J., Zhao, S. D., Bradfield, J. P., Mentch, F. D., Maggadottir, S. M., Hou, C., Abrams, D. J., Chang, D., Gao, F., et al. (2015) · Nature Medicine · doi:10.1038/nm.3933 · Cited by 261 · see citing works

Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types

Chun, S., Casparino, A., Patsopoulos, N. A., Croteau-Chonka, D. C., Raby, B. A., De Jager, P. L., Sunyaev, S. R., & Cotsapas, C. (2017) · Nature Genetics · doi:10.1038/ng.3795 · Cited by 259 · see citing works

Autoimmune diseases — connecting risk alleles with molecular traits of the immune system

Gutiérrez‐Arcelus, M., Rich, S. S., & Raychaudhuri, S. (2015) · Nature Reviews Genetics · doi:10.1038/nrg.2015.33 · Cited by 254 · see citing works

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

Sun, C., Molineros, J. E., Looger, L. L., Zhou, S., Kim, K.-W., Okada, Y., Ma, J., Qi, Y., Kim-Howard, X., Motghare, P. N., et al. (2016) · Nature Genetics · doi:10.1038/ng.3496 · Cited by 251 · see citing works

Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

Asselbergs, F. W., Guo, Y., van Iperen, E. P. A., Sivapalaratnam, S., Tragante, V., Lanktree, M. B., Lange, L. A., Almoguera, B., Appelman, Y., Barnard, J., et al. (2012) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2012.08.032 · Cited by 247 · see citing works

Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

Liu, Z., Liu, R., Gao, H., Jung, S., Gao, X., Sun, R., Liu, X., Kim, Y., Lee, H., Kawai, Y., et al. (2023) · Nature Genetics · doi:10.1038/s41588-023-01384-0 · Cited by 244 · see citing works

Visualizing genomic information across chromosomes with PhenoGram

Wolfe, D., DUDEK, S. M., Ritchie, M. D., & Pendergrass, S. A. (2013) · BioData Mining · doi:10.1186/1756-0381-6-18 · Cited by 243 · see citing works

Human and Helicobacter pylori coevolution shapes the risk of gastric disease

Kodaman, N. M., Pazos, A. J., Schneider, B., Piazuelo, M. B., Mera, R. M., Sobota, R. S., Sicinschi, L. A., Shaffer, C. L., Romero–Gallo, J., de Sablet, T., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1318093111 · Cited by 236 · see citing works

Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease

Hrdličková, B., de Almeida, R. C., Borek, Z., & Withoff, S. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.03.011 · Cited by 233 · see citing works

Understanding type 1 diabetes through genetics: advances and prospects

Polychronakos, C., & Li, Q. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3069 · Cited by 226 · see citing works

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

Lee, J. C., Espéli, M., Anderson, C. A., Linterman, M. A., Pocock, J., Williams, N. J., Roberts, R. L., Viatte, S., Fu, B., Peshu, N. M., et al. (2013) · Cell · doi:10.1016/j.cell.2013.08.034 · Cited by 226 · see citing works

Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis

Hedström, A. K., Bomfim, I. L., Barcellos, L. F., Gianfrancesco, M. A., Schaefer, C. A., Kockum, I. S., Olsson, T. P., & Alfredsson, L. S. (2014) · Neurology · doi:10.1212/wnl.0000000000000203 · Cited by 223 · see citing works

Genetics of rheumatoid arthritis

Padyukov, L. (2022) · Seminars in Immunopathology · doi:10.1007/s00281-022-00912-0 · Cited by 216 · see citing works

Immunochip Analysis Identifies Multiple Susceptibility Loci for Systemic Sclerosis

Mayes, M. D., Bossini‐Castillo, L., Gorlova, O. Y., Martín, J., Zhou, X., Chen, W. V., Assassi, S., Ying, J., Tan, F. K., Arnett, F. C., et al. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2013.12.002 · Cited by 208 · see citing works

The immunogenetics of Behçet's disease: A comprehensive review

Takeuchi, M., Kastner, D. L., & Remmers, E. F. (2015) · Journal of Autoimmunity · doi:10.1016/j.jaut.2015.08.013 · Cited by 204 · see citing works

Genetic variants in mRNA untranslated regions

Steri, M., Idda, M. L., Whalen, M. B., & Orrù, V. (2018) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1474 · Cited by 200 · see citing works

Revisiting the gut–joint axis: links between gut inflammation and spondyloarthritis

Gracey, E., Vereecke, L., McGovern, D. P. B., Fröhling, M., Schett, G. A., Danese, S., Vos, M. D., den Bosch, F. E. V., & Elewaut, D. S. (2020) · Nature Reviews Rheumatology · doi:10.1038/s41584-020-0454-9 · Cited by 198 · see citing works

Psoriasis and Genetics

Dand, N., Mahil, S. K., Capon, F., Smith, C. H., Simpson, M. A., & Barker, J. N. (2020) · Acta Dermato Venereologica · doi:10.2340/00015555-3384 · Cited by 192 · see citing works

Innate Immune Activity Is Detected Prior to Seroconversion in Children With HLA-Conferred Type 1 Diabetes Susceptibility

Kallionpää, H., Elo, L. L., Laajala, E., Mykkänen, J., Ricaño-Ponce, I., Vaarma, M., Laajala, T. D., Hyöty, H., Ilonen, J., Veijola, R., et al. (2014) · Diabetes · doi:10.2337/db13-1775 · Cited by 187 · see citing works

A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases

Zhao, J. H., Ma, J., Deng, Y., Kelly, J. A., Kim, K.-W., Bang, S., Lee, H., Li, Q., Wakeland, E. K., Qiu, R., et al. (2017) · Nature Genetics · doi:10.1038/ng.3782 · Cited by 184 · see citing works

A Large-Scale Genetic Analysis Reveals a Strong Contribution of the HLA Class II Region to Giant Cell Arteritis Susceptibility

Carmona, F. D., Mackie, S. L., Martín, J., Taylor, J., Vaglio, A., Eyre, S., Bossini‐Castillo, L., Castañeda, S., Cid, M. C., Hernández‐Rodríguez, J., et al. (2015) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.02.009 · Cited by 177 · see citing works

Coeliac disease and autoimmune disease—genetic overlap and screening

Lundin, K. E. A., & Wijmenga, C. (2015) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2015.136 · Cited by 175 · see citing works

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Su, Z., Gay, L. J., Strange, A., Palles, C., Band, G., Whiteman, D. C., Lescai, F., Langford, C., Nanji, M. S., Edkins, S., et al. (2012) · Nature Genetics · doi:10.1038/ng.2408 · Cited by 171 · see citing works

Complement genetics, deficiencies, and disease associations

Mayilyan, K. R. (2012) · Protein & Cell · doi:10.1007/s13238-012-2924-6 · Cited by 166 · see citing works

Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility

Takeuchi, M., Mizuki, N., Meguro, A., Ombrello, M. J., Kirino, Y., Satorius, C., Le, J., Blake, M., Erer, B., Kawagoe, T., et al. (2017) · Nature Genetics · doi:10.1038/ng.3786 · Cited by 164 · see citing works

Unique roles of rare variants in the genetics of complex diseases in humans

Momozawa, Y., & Mizukami, K. (2021) · Journal of Human Genetics · doi:10.1038/s10038-020-00845-2 · Cited by 161 · see citing works

Genetics of diabetes – Are we missing the genes or the disease?

Groop, L., & Pociot, F. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.04.002 · Cited by 158 · see citing works

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

Imgenberg‐Kreuz, J., Almlöf, J. C., Leonard, D., Alexsson, A., Nordmark, G., Eloranta, M., Rantapää‐Dahlqvist, S., Bengtsson, A. A., Jönsen, A., Padyukov, L., et al. (2018) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2017-212379 · Cited by 156 · see citing works

Immunogenetics of juvenile idiopathic arthritis: A comprehensive review

Hersh, A. O., & Prahalad, S. (2015) · Journal of Autoimmunity · doi:10.1016/j.jaut.2015.08.002 · Cited by 150 · see citing works

Seven newly identified loci for autoimmune thyroid disease

Cooper, J. D., Simmonds, M. J., Walker, N. M., Burren, O. S., Brand, O. J., Guo, H., Wallace, C., Stevens, H. E., Coleman, G., Franklyn, J. A., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds357 · Cited by 149 · see citing works

A combined risk score enhances prediction of type 1 diabetes among susceptible children

Ferrat, L. A., Vehik, K., Sharp, S. A., Lernmark, Å., Rewers, M. J., She, J.-X., Ziegler, A.-G., Toppari, J., Akolkar, B., Krischer, J. P., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0930-4 · Cited by 148 · see citing works

A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation

Naitza, S., Porcu, E., Steri, M., Taub, D. D., Mulas, A., Xiao, X., Strait, J., Dei, M., Lai, S., Busonero, F., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002480 · Cited by 148 · see citing works

Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings

Hedin, C. R. H., McCarthy, N. E., Louis, P., Farquharson, F. M., McCartney, S. A., Taylor, K. M., Prescott, N. J., Murrells, T., Stagg, A. J., Whelan, K., et al. (2014) · Gut · doi:10.1136/gutjnl-2013-306226 · Cited by 145 · see citing works

From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases

Kumar, V., Wijmenga, C., & Withoff, S. (2012) · Seminars in Immunopathology · doi:10.1007/s00281-012-0312-1 · Cited by 143 · see citing works

Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers

López‐Mejías, R., Castañeda, S., González‐Juanatey, C., Corrales, A., Ferraz‐Amaro, I., Genre, F., Remuzgo‐Martínez, S., Rodríguez‐Rodríguez, L., Blanco, R., Llorca, J., et al. (2016) · Autoimmunity Reviews · doi:10.1016/j.autrev.2016.07.026 · Cited by 134 · see citing works

An unsupervised machine learning method for discovering patient clusters based on genetic signatures

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The Genetic Basis of Vitiligo

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Updates in Lupus Genetics

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