10 Years of GWAS Discovery: Biology, Function, and Translation

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Finding the missing heritability of complex diseases

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Biological insights from 108 schizophrenia-associated genetic loci

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Integrative analysis of 111 reference human epigenomes

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Genetics and Analysis of Quantitative Traits

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Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

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‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

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LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

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The Future of Genetic Studies of Complex Human Diseases

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

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Common SNPs explain a large proportion of the heritability for human height

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An atlas of genetic correlations across human diseases and traits

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A unified mixed-model method for association mapping that accounts for multiple levels of relatedness

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Genome-wide efficient mixed-model analysis for association studies

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Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

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Rapid and Accurate Haplotype Phasing and Missing-Data Inference for Whole-Genome Association Studies By Use of Localized Haplotype Clustering

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A reference panel of 64,976 haplotypes for genotype imputation

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Variance component model to account for sample structure in genome-wide association studies

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Synaptic, transcriptional and chromatin genes disrupted in autism

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The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

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A new multipoint method for genome-wide association studies by imputation of genotypes

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Partitioning heritability by functional annotation using genome-wide association summary statistics

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The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

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Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

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The contribution of de novo coding mutations to autism spectrum disorder

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Integrative approaches for large-scale transcriptome-wide association studies

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Five Years of GWAS Discovery

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Schizophrenia risk from complex variation of complement component 4

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

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Human gut microbes impact host serum metabolome and insulin sensitivity

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Genetics and analysis of quantitative traits

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Genetic and epigenetic fine mapping of causal autoimmune disease variants

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Heritability in the genomics era — concepts and misconceptions

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

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Defining the role of common variation in the genomic and biological architecture of adult human height

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MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

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A gene-based association method for mapping traits using reference transcriptome data

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Personal genomes: The case of the missing heritability

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Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

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Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

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The support of human genetic evidence for approved drug indications

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De novo mutations in schizophrenia implicate synaptic networks

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Efficient Bayesian mixed-model analysis increases association power in large cohorts

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Genome-wide association analysis identifies 13 new risk loci for schizophrenia

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Branched-chain amino acids in metabolic signalling and insulin resistance

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<i>FTO</i> Obesity Variant Circuitry and Adipocyte Browning in Humans

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FaST linear mixed models for genome-wide association studies

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Detection and interpretation of shared genetic influences on 42 human traits

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Genotype Imputation with Millions of Reference Samples

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Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

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The genetic architecture of type 2 diabetes

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The role of regulatory variation in complex traits and disease

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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

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Advantages and pitfalls in the application of mixed-model association methods

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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

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LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

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Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

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Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

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DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

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Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

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Properties of a neutral allele model with intragenic recombination

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A Versatile Gene-Based Test for Genome-wide Association Studies

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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

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Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

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Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

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Prediction of individual genetic risk to disease from genome-wide association studiesPreprint

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Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

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Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

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Rare and low-frequency coding variants alter human adult height

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Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

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Chromosome conformation elucidates regulatory relationships in developing human brain

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Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

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Genome-wide association study identifies multiple loci influencing human serum metabolite levels

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Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

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Abundant Pleiotropy in Human Complex Diseases and Traits

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Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

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Genetic insights into common pathways and complex relationships among immune-mediated diseases

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