The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
VPS35-deficiency results in an impaired AMPA receptor trafficking and decreased dendritic spine maturation
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VPS35 suppression decreased surface levels of GLUT1/SLC2A1, AMPA receptors GRIA2, GRIA3, GRIA4, NMDA receptors GRIN1, GRIN2b, and SLC4A7.
“Validating our approach, downregulated proteins included the wellestablished Retromer cargo glucose transporter-1 (GLUT1/SLC2A1) [29], the ionotropic glutamate AMPA receptors (GRIA2, GRIA3, GRIA4) and NMDA receptors (GRIN1, GRIN2b) [80][81][82][83][84][85], as well as many other previously identified proteins including the sodium bicarbonate cotransporter-3 (SLC4A7) (Figure 1D, Supplementary Table”
From Global identification of neuronal and astrocytic integral membrane proteins that require Retromer for their endosomal recycling (2026) · cites this paper as [84]
The Results (Fig. 5; page not provided) show reduced cell-surface GluA2 (GRIA2) in VPS35-deficient neurons. They do not report reduced surface levels of GRIA3, GRIA4, GRIN1, or GRIN2B; the Discussion mentions NMDA receptors only when describing another study. The separate GLUT1 citation in the citing sentence is not attributed to this paper, and this paper does not establish a surface-level decrease for SLC4A7. (LLM, conf=0.88)
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Cites
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The needs of a synapse—How local organelles serve synaptic proteostasis
Grochowska, K. M., Andres‐Alonso, M., Karpova, A., & Kreutz, M. R. (2022) · The EMBO Journal · doi:10.15252/embj.2021110057 · Cited by 38
Receptor Recycling by Retromer
Carosi, J. M., Denton, D., Kumar, S., & Sargeant, T. J. (2023) · Molecular and Cellular Biology · doi:10.1080/10985549.2023.2222053 · Cited by 36
Jones, E., Adams, H., Chen, K.-E., Maroof, F., Ibbotson, T. M., Nakamura, Y., Banks, P. J., Healy, M. D., Lewis, P. A., Heesom, K. J., et al. (2026) · doi:10.64898/2026.05.14.724903
Metadata
- Authors
- Tian, Y., Tang, F.-L., Sun, X., Wen, L., Mei, L., Tang, B.-S., & Xiong, W.-C.
- Venue
- Molecular Brain
- Published
- 2015-10-31
- Volume
- 8
- Issue
- 1
- ISSN
- 1756-6606
- PMC
- PMC4628247
- Cited by
- 76
- References
- 6
- Language
- en
- Funders
- National Institute of Aging (AG045781)
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