Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer’s disease

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Identification of altered exosomal microRNAs and mRNAs in Alzheimer's disease

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Primary cilia and ciliary signaling pathways in aging and age-related brain disorders

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Mesenchymal stem cells-derived extracellular vesicles ameliorate Alzheimer’s disease in rat models via the microRNA-29c-3p/BACE1 axis and the Wnt/β-catenin pathway

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Genetics of common cerebral small vessel disease

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GSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions

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Crosstalk of Brain and Bone—Clinical Observations and Their Molecular Bases

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Neuroprotective Effects of Phytochemicals against Aluminum Chloride-Induced Alzheimer’s Disease through ApoE4/LRP1, Wnt3/β-Catenin/GSK3β, and TLR4/NLRP3 Pathways with Physical and Mental Activities in a Rat Model

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Insulin resistance as the molecular link between diabetes and Alzheimer's disease

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Neuropathological Mechanisms Associated with Pesticides in Alzheimer’s Disease

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Role of Hydrazine-Related Chemicals in Cancer and Neurodegenerative Disease

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Targeting the Wnt/β-catenin pathway in neurodegenerative diseases: recent approaches and current challenges

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Novel Insight to Neuroprotective Potential of Curcumin: A Mechanistic Review of Possible Involvement of Mitochondrial Biogenesis and PI3/Akt/ GSK3 or PI3/Akt/CREB/BDNF Signaling Pathways.

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Assessment of Inner Blood–Retinal Barrier: Animal Models and Methods

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Damage mechanism and therapy progress of the blood-brain barrier after ischemic stroke

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Pyruvate kinase isoform M2 impairs cognition in systemic lupus erythematosus by promoting microglial synaptic pruning via the β-catenin signaling pathway

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The Molecular Basis of Wnt/β-Catenin Signaling Pathways in Neurodegenerative Diseases

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Tadalafil and bergapten mitigate streptozotocin-induced sporadic Alzheimer's disease in mice via modulating neuroinflammation, PI3K/Akt, Wnt/β-catenin, AMPK/mTOR signaling pathways

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Role of Wnt signaling in synaptic plasticity and memory

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Bone-organ axes: bidirectional crosstalk

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Cannabidiol goes nuclear: The role of PPARγ

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JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer’s disease

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The Molecular Effects of Environmental Enrichment on Alzheimer’s Disease

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The Occurrence of Alzheimer’s Disease and Parkinson’s Disease in Individuals With Osteoporosis: A Longitudinal Follow-Up Study Using a National Health Screening Database in Korea

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Alzheimer’s Disease: An Overview of Major Hypotheses and Therapeutic Options in Nanotechnology

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Role of primary aging hallmarks in Alzheimer´s disease

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Insulin resistance and bioenergetic manifestations: Targets and approaches in Alzheimer's disease

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Impaired Learning and Memory Ability Induced by a Bilaterally Hippocampal Injection of Streptozotocin in Mice: Involved With the Adaptive Changes of Synaptic Plasticity

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Blood Markers of Inflammation, Neurodegeneration, and Cardiovascular Risk in Early Parkinson's Disease

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Distinct types of amyloid‐β oligomers displaying diverse neurotoxicity mechanisms in Alzheimer's disease

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Blockage of VEGF function by bevacizumab alleviates early-stage cerebrovascular dysfunction and improves cognitive function in a mouse model of Alzheimer’s disease

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Sex, hormones and cerebrovascular function: from development to disorder

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Potential Roles of the WNT Signaling Pathway in Amyotrophic Lateral Sclerosis

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Integration of network pharmacology and molecular docking to explore the molecular mechanism of Cordycepin in the treatment of Alzheimer’s disease

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Molecular mechanisms and therapeutic potential of lithium in Alzheimer’s disease: repurposing an old class of drugs

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Blood–brain barrier disruption: a pervasive driver and mechanistic link between traumatic brain injury and Alzheimer's disease

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Ten Years of EWAS

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Bone marrow mesenchymal stem cells and their derived exosomes resolve doxorubicin-induced chemobrain: critical role of their miRNA cargo

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Neuropilin-1 promotes mitochondrial structural repair and functional recovery in rats with cerebral ischemia

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Long-lasting restoration of memory function and hippocampal synaptic plasticity by focused ultrasound in Alzheimer's disease

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Aberrant canonical Wnt signaling: Phytochemical based modulation

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Neuroprotective potential of quercetin in Alzheimer’s disease: targeting oxidative stress, mitochondrial dysfunction, and amyloid-β aggregation

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Interaction of NF-κB and Wnt/β-catenin Signaling Pathways in Alzheimer’s Disease and Potential Active Drug Treatments

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Cannabis sativa and Cannabidiol: A Therapeutic Strategy for the Treatment of Neurodegenerative Diseases?

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The Signalling Effects of Photobiomodulation on Osteoblast Proliferation, Maturation and Differentiation: A Review

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The possible role of Wnt/β‐catenin signalling in vitiligo treatment

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The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways

Abu‐Elfotuh, K., Selim, H. M. R. M., Riad, O. K. M., Hamdan, A. M., Hassanin, S. O., Sharif, A. F., Moustafa, N. M., Gowifel, A. M. H., Mohamed, M. Y. A., Atwa, A. M., et al. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1208252 · Cited by 36

Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation

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Neuronal transcriptome, tau and synapse loss in Alzheimer’s knock-in mice require prion protein

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Inflammation-Related circRNA Polymorphism and Ischemic Stroke Prognosis

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On the Common Journey of Neural Cells through Ischemic Brain Injury and Alzheimer’s Disease

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Activation of Wnt/β-catenin pathway causes insulin resistance and increases lipogenesis in HepG2 cells via regulation of endoplasmic reticulum stress

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Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer’s Disease Rats Based on the Wnt/β-catenin Pathway

Ning, W.-J., Lv, R., Xu, N., Hou, X., Shen, C., Guo, Y., Fan, Z., Cao, N., & Liu, X. (2021) · Neural Plasticity · doi:10.1155/2021/5519330 · Cited by 32

A Tau Pathogenesis-Based Network Pharmacology Approach for Exploring the Protections of Chuanxiong Rhizoma in Alzheimer’s Disease

Zeng, P. H., Su, H.-F., Ye, C., Qiu, S.-W., Shi, A., Wang, J., Zhou, X., & Tian, Q. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.877806 · Cited by 32

Osteoporosis and Alzheimer´s disease (or Alzheimer´s disease and Osteoporosis)

Wanionok, N. E., Morel, G. R., & Fernández, J. M. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102408 · Cited by 31

Estrogen signalling and Alzheimer's disease: Decoding molecular mechanisms for therapeutic breakthrough

Rishabh, R., Rohilla, M., Bansal, S., Bansal, N., Chauhan, S., Sharma, S., Goyal, N., & Gupta, S. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16360 · Cited by 31

Protective Effects of Polydatin Against Dementia-Related Disorders

Tang, K. S. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200611144825 · Cited by 29

WNT Signaling Is a Key Player in Alzheimer’s Disease

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Molecular Insights to the Wnt Signaling During Alzheimer’s Disorder: a Potential Target for Therapeutic Interventions

Nagu, P., Sharma, V., Behl, T., Pathan, A. K., & Mehta, V. (2022) · Journal of Molecular Neuroscience · doi:10.1007/s12031-021-01940-5 · Cited by 28

Mechanisms and structure-activity relationships of polysaccharides in the intervention of Alzheimer's disease: A review

Tang, J., Yousaf, M., Wu, Y., Li, Q., Xu, Y., & Liu, D. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.127553 · Cited by 27

Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer’s Disease

Li, Q., Rubin, L., Silva, M., Li, S., Yang, C., Lazarovici, P., & Zheng, W. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/3777021 · Cited by 28

Multi-context genetic modeling of transcriptional regulation resolves novel disease loci

Thompson, M., Gordon, M. G., Lu, A. C., Tandon, A., Halperin, E., Gusev, A., Ye, C., Balliu, B., & Zaitlen, N. (2022) · Nature Communications · doi:10.1038/s41467-022-33212-0 · Cited by 28

Signaling Pathways Involved in the Neuroprotective Effect of Osthole: Evidence and Mechanisms

Singh, L., & Bhatti, R. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03580-9 · Cited by 27

From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis

Grünblatt, E., Homolak, J., Perhoč, A. B., Virag, D., Knezović, A., Barilar, J. O., Riederer, P., Walitza, S., Tackenberg, C., & Šalković‐Petrišić, M. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1104985 · Cited by 26

Aging alters mechanisms underlying voluntary movements in spinal motor neurons of mice, primates, and humans

Castro, R. W., Lopes, M. C., Settlage, R. E., & Valdez, G. (2023) · JCI Insight · doi:10.1172/jci.insight.168448 · Cited by 26

From the Mind to the Spine: The Intersecting World of Alzheimer’s and Osteoporosis

Margetts, T. J., Wang, H. S., Karnik, S. J., Plotkin, L. I., Movilă, A., Oblak, A. L., Fehrenbacher, J. C., & Kacena, M. A. (2024) · Current Osteoporosis Reports · doi:10.1007/s11914-023-00848-w · Cited by 26

Molecular mechanisms of altered adult hippocampal neurogenesis in Alzheimer's disease

Liu, H., Zhang, H., & Ma, Y. (2021) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2021.111452 · Cited by 25

Icarisid II rescues cognitive dysfunction via activation of Wnt/β‐catenin signaling pathway promoting hippocampal neurogenesis in APP / PS1 transgenic mice

Xiao, H., Chen, J., Li, H., Li, R., Wang, H., Song, H., Li, H., Shan, G., Tian, Y., Zhao, Y., et al. (2022) · Phytotherapy Research · doi:10.1002/ptr.7430 · Cited by 25

Crosstalk between bone and other organs

Yuan, W., & Song, C. (2022) · Medical Review · doi:10.1515/mr-2022-0018 · Cited by 27

Wnt10b-GSK3β–dependent Wnt/STOP signaling prevents aneuploidy in human somatic cells

Lin, Y., Haas, A., Bufe, A., Parbin, S., Hennecke, M., Voloshanenko, O., Gross, J. C., Boutros, M., Acebrón, S. P., & Bastians, H. (2020) · Life Science Alliance · doi:10.26508/lsa.202000855 · Cited by 27

MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer’s disease

Wan, W., Liu, G., Li, X., Liu, Y., Wang, Y., Pan, H., & Hu, J. (2021) · Bioengineered · doi:10.1080/21655979.2021.2008638 · Cited by 25

Misregulation of Wnt Signaling Pathways at the Plasma Membrane in Brain and Metabolic Diseases

Karabicici, M., Azbazdar, Y., İşcan, E., & Özhan, G. (2021) · Membranes · doi:10.3390/membranes11110844 · Cited by 23

Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response

Yousef, M. H., Salama, M., El‐Fawal, H. A. N., & Abdelnaser, A. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02923-2 · Cited by 23

Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer’s Disease

Macyczko, J. R., Wang, N., Zhao, J., Ren, Y., Lü, W., Ikezu, T. C., Zhao, N., Liu, C., Bu, G., & Li, Y. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-03065-1 · Cited by 25

Mind Gaps and Bone Snaps: Exploring the Connection Between Alzheimer’s Disease and Osteoporosis

Wang, H. S., Karnik, S. J., Margetts, T. J., Plotkin, L. I., Movilă, A., Fehrenbacher, J. C., Kacena, M. A., & Oblak, A. L. (2024) · Current Osteoporosis Reports · doi:10.1007/s11914-023-00851-1 · Cited by 24

Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β‐catenin signaling pathway

Liu, J., Wei, A., Liu, T., Ji, X., Zhang, Y., Yan, F., Chen, M., Hu, J., Zhou, S., Shi, J., et al. (2024) · FEBS Journal · doi:10.1111/febs.17099 · Cited by 24

Resveratrol ameliorates learning and memory impairments induced by bilateral hippocampal injection of streptozotocin in mice

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Neurotrophic factor-secreting cells restored endogenous hippocampal neurogenesis through the Wnt/β-catenin signaling pathway in AD model mice

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