Psychosocial and pharmacologic interventions for methamphetamine addiction: protocol for a scoping review of the literature
Open accessAbstract
BACKGROUND: Methamphetamine use and harms are rising rapidly. Management of patients with methamphetamine use disorder (MUD) and problematic methamphetamine use (PMU) is challenging, with no clearly established best approach; both psychosocial and pharmacologic interventions have been described. Furthermore, given the diversity of individuals that use methamphetamines, there is a need to assess evidence for treatments for subgroups including youths; gay, bisexual, and other men who have sex with men; individuals with mental health comorbidities; and individuals in correction services. Establishing awareness of the messages regarding treatment from recent clinical practice guidelines (CPG) in the field is also of value. The first study objective will be to establish a greater understanding of the methods, populations, and findings of controlled studies for psychosocial and pharmacologic treatments for MUD and PMU. Investigation of this information can help establish the potential for advanced syntheses of the evidence (such as network meta-analysis) to compare therapies for this condition and to identify gaps related to key populations where more primary research is needed. Summarizing the recommendations regarding treatment of MUD/PMU from recent CPGs and systematic reviews will be an important secondary objective. METHODS: A scoping review will be performed. Using the OVID platform, MEDLINE, Embase, PsycINFO, and relevant Cochrane databases from EBM Reviews will be searched (from databases' inception onwards). Eligibility criteria will include individuals described as having MUD or PMU, with designs of interest including randomized trials, non-randomized trials, and controlled cohort studies with three or more months of follow-up; systematic reviews and CPGs will also be sought. Two reviewers (with support from automation tools) will independently screen all citations, full-text articles, and chart data. Different approaches to handling and summarizing the data will be implemented for each type of study design. Tables and graphics will be used to map evidence sources and identify evidence gaps. DISCUSSION: This research will enhance awareness of evidence addressing the effects of psychosocial and pharmacologic interventions for MUD/PMU overall and in sub-populations, both in terms of recent CPGs/reviews and primary studies; inspection of the latter will also help establish the feasibility of future syntheses to compare treatments, such as network meta-analysis. SYSTEMATIC REVIEW PROTOCOL REGISTRATION: Open Science Framework ( https://osf.io/9wy8p ).
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The review was guided by an a priori protocol.
“Guided by an a priori protocol, electronic database search updates (e.g., MEDLINE, Embase) were performed in February 2022.”
From Psychosocial and pharmacologic interventions for problematic methamphetamine use: Findings from a scoping review of the literature (2023) · cites this paper as [31]
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Hamel, C., Hersi, M., Kelly, S. E., Tricco, A. C., Straus, S., Wells, G., Pham, B., & Hutton, B. (2021) · BMC Medical Research Methodology · doi:10.1186/s12874-021-01451-2 · Cited by 104 · see citing works
Self-citationTran, M. T. N., Luong, Q. H., Le Minh, G., Dunne, M. P., & Baker, P. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.512076 · Cited by 42 · see citing works
Hersi, M., Corace, K., Hamel, C., Esmaeilisaraji, L., Rice, D., Dryburgh, N., Skidmore, B., Garber, G., Porath, A., Willows, M., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0292745 · Cited by 13 · see citing works
Self-citation
- Authors
- Hamel, C., Corace, K., Hersi, M., Rice, D., Willows, M., Macpherson, P., Sproule, B., Flores-Aranda, J., Garber, G., Esmaeilisaraji, L., Skidmore, B., Porath, A., Ortiz Nunez, R., & Hutton, B.
- Affiliations
- Ottawa Hospital (CA)
- University of Ottawa (CA)
- Centre for Addiction and Mental Health (CA)
- Université du Québec à Montréal (CA)
- Canadian Centre on Substance Use and Addiction (CA)
- Corresponding author
- Hutton, B.
- ORCID
- Venue
- Systematic Reviews
- Published
- 2020-10-24
- Volume
- 9
- Issue
- 1
- Pages
- 245-245
- ISSN
- 2046-4053 (ISSN-L)
- PMC
- PMC7585172
- OpenAlex
- W3093533526
- Cited by
- 17
- References
- 90
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 4
- FWCI
- 2.15
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Systematic Reviews (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- uO Research (University of Ottawa) (submittedVersion, public-domain)
- TSpace (University of Toronto) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Canadian Institutes of Health Research (201909MPU-428758-MPU-ADYP-170629)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- methamphetamine dependence, psychosocial interventions, pharmacological interventions, addiction treatment, adolescent substance use, men who have sex with men, psychiatric comorbidity, correctional populations, evidence gaps, network meta-analysis
- MeSH terms
- Network Meta-Analysis, Sexual and Gender Minorities, Scoping Review as Topic, Scoping Reviews as Topic, Scoping Reviews As Topic, Adolescent, Humans, Male, Methamphetamine, Review Literature as Topic, Meta-Analysis as Topic, Behavior, Addictive, Homosexuality, Male
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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