Cited by 17Substance Abuse Treatment and OutcomesOpioid Use Disorder TreatmentHIV, Drug Use, Sexual Risk

Psychosocial and pharmacologic interventions for methamphetamine addiction: protocol for a scoping review of the literature

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Hamel, C., Corace, K., Hersi, M., Rice, D., Willows, M., Macpherson, P., Sproule, B., Flores-Aranda, J. +6 more·2020·Systematic Reviews

Abstract

BACKGROUND: Methamphetamine use and harms are rising rapidly. Management of patients with methamphetamine use disorder (MUD) and problematic methamphetamine use (PMU) is challenging, with no clearly established best approach; both psychosocial and pharmacologic interventions have been described. Furthermore, given the diversity of individuals that use methamphetamines, there is a need to assess evidence for treatments for subgroups including youths; gay, bisexual, and other men who have sex with men; individuals with mental health comorbidities; and individuals in correction services. Establishing awareness of the messages regarding treatment from recent clinical practice guidelines (CPG) in the field is also of value. The first study objective will be to establish a greater understanding of the methods, populations, and findings of controlled studies for psychosocial and pharmacologic treatments for MUD and PMU. Investigation of this information can help establish the potential for advanced syntheses of the evidence (such as network meta-analysis) to compare therapies for this condition and to identify gaps related to key populations where more primary research is needed. Summarizing the recommendations regarding treatment of MUD/PMU from recent CPGs and systematic reviews will be an important secondary objective. METHODS: A scoping review will be performed. Using the OVID platform, MEDLINE, Embase, PsycINFO, and relevant Cochrane databases from EBM Reviews will be searched (from databases' inception onwards). Eligibility criteria will include individuals described as having MUD or PMU, with designs of interest including randomized trials, non-randomized trials, and controlled cohort studies with three or more months of follow-up; systematic reviews and CPGs will also be sought. Two reviewers (with support from automation tools) will independently screen all citations, full-text articles, and chart data. Different approaches to handling and summarizing the data will be implemented for each type of study design. Tables and graphics will be used to map evidence sources and identify evidence gaps. DISCUSSION: This research will enhance awareness of evidence addressing the effects of psychosocial and pharmacologic interventions for MUD/PMU overall and in sub-populations, both in terms of recent CPGs/reviews and primary studies; inspection of the latter will also help establish the feasibility of future syntheses to compare treatments, such as network meta-analysis. SYSTEMATIC REVIEW PROTOCOL REGISTRATION: Open Science Framework ( https://osf.io/9wy8p ).

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  1. [32]Stoner S Effective treatments for methamphetamine use disorder: a review 2018
  2. [46]Grigg J, Manning V, Arunogiri S, et al. Methamphetamine treatment guidelines: practice guidelines for health professionals (2nd edition). 2018. https://www.turningpoint.org.au/sites/default/files/2019-05/Turning-Point-Methamphetamine-Treatment-Guidelines.pdf. [Accessed 2 Sept 2019].

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Authors
Hamel, C., Corace, K., Hersi, M., Rice, D., Willows, M., Macpherson, P., Sproule, B., Flores-Aranda, J., Garber, G., Esmaeilisaraji, L., Skidmore, B., Porath, A., Ortiz Nunez, R., & Hutton, B.
Affiliations
  • Ottawa Hospital (CA)
  • University of Ottawa (CA)
  • Centre for Addiction and Mental Health (CA)
  • Université du Québec à Montréal (CA)
  • Canadian Centre on Substance Use and Addiction (CA)
Corresponding author
Hutton, B.
Venue
Systematic Reviews
Published
2020-10-24
Volume
9
Issue
1
Pages
245-245
ISSN
2046-4053 (ISSN-L)
OpenAlex
W3093533526
Cited by
17
References
90
Citations by year
2026: 1 · 2025: 3 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 4
FWCI
2.15
Type
journal article
Language
en
Open access
Locations
  • Systematic Reviews (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • uO Research (University of Ottawa) (submittedVersion, public-domain)
  • TSpace (University of Toronto) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Canadian Institutes of Health Research (201909MPU-428758-MPU-ADYP-170629)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
  • Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
Keywords
methamphetamine dependence, psychosocial interventions, pharmacological interventions, addiction treatment, adolescent substance use, men who have sex with men, psychiatric comorbidity, correctional populations, evidence gaps, network meta-analysis
MeSH terms
Network Meta-Analysis, Sexual and Gender Minorities, Scoping Review as Topic, Scoping Reviews as Topic, Scoping Reviews As Topic, Adolescent, Humans, Male, Methamphetamine, Review Literature as Topic, Meta-Analysis as Topic, Behavior, Addictive, Homosexuality, Male

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