Cited by 329Artificial Intelligence in Healthcare and EducationArtificial Intelligence in HealthcareArtificial Intelligence Applications

Artificial Intelligence in Healthcare and Medicine: Clinical Applications, Therapeutic Advances, and Future Perspectives

Open access
Fahim, Yosri A., Hasani, Ibrahim W., Kabba, Samer, Ragab, Waleed Mahmoud·2025·European Journal of Medical Research

Abstract

Healthcare systems worldwide face growing challenges, including rising costs, workforce shortages, and disparities in access and quality, particularly in low- and middle-income countries. Artificial intelligence (AI) has emerged as a transformative tool capable of addressing these issues by enhancing diagnostics, treatment planning, patient monitoring, and healthcare efficiency. AI's role in modern medicine spans disease detection, personalized care, drug discovery, predictive analytics, telemedicine, and wearable health technologies. Leveraging machine learning and deep learning, AI can analyze complex data sets, including electronic health records, medical imaging, and genomic profiles, to identify patterns, predict disease progression, and recommend optimized treatment strategies. AI also has the potential to promote equity by enabling cost-effective, resource-efficient solutions in low-resource and remote settings, such as mobile diagnostics, wearable biosensors, and lightweight algorithms. Successful deployment requires addressing critical challenges, including data privacy, algorithmic bias, model interpretability, regulatory oversight, and maintaining human clinical oversight. Emphasizing scalable, ethical, and evidence-driven implementation, key strategies include clinician training in AI literacy, adoption of resource efficient tools, global collaboration, and robust regulatory frameworks to ensure transparency, safety, and accountability. By complementing rather than replacing healthcare professionals, AI can reduce errors, optimize resources, improve patient outcomes, and expand access to quality care. This review emphasizes the responsible integration of AI as a powerful catalyst for innovation, sustainability, and equity in healthcare delivery worldwide.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1186/s40001-025-03196-w

Cites

20 of 20 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Deep learning models can identify intricate patterns within large datasets without requiring explicit feature selection.

    “Unlike traditional rule-based approaches, deep learning models can identify intricate patterns within large datasets without requiring explicit feature selection [3].”

    From Deep Learning Applied to 12-Lead ECGs for Detection of Structural, Metabolic and Systemic Disease (2026) · cites this paper as [3]

    The Foundational AI technologies sections (Deep learning and Machine learning; pages unavailable) say that deep learning represents complex, high-dimensional data and enhances feature extraction, while machine learning recognizes patterns in extensive, intricate datasets. They do not establish that deep learning requires no explicit feature selection or make the claimed comparison with traditional rule-based approaches. (LLM, conf=0.78)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 160

  1. [1]Yeganeh H. An analysis of emerging trends and transformations in global healthcare. Int J Health Gov. 2019;24(2):169–80.
  2. [2]Tabish SA, Nabil S. Future of healthcare delivery: strategies that will reshape the healthcare industry landscape. Int J Sci Res. 2015;4(2):727–58.
  3. [3]Sheth A, Roy K, Gaur M. Neurosymbolic artificial intelligence (why, what, and how). IEEE Intell Syst. 2023;38(3):56–62. · DOI
  4. [4]Suriyaamporn P, et al. The artificial intelligence-powered new era in pharmaceutical research and development: a review. AAPS PharmSciTech. 2024;25(6):188. 39147952 · DOI
  5. [5]Patil S, Shankar H. Transforming healthcare: harnessing the power of AI in the modern era. Int J Multidiscip Sci Arts. 2023;2(2):60–70.
  6. [6]Ahmed Z, et al. Artificial intelligence with multi-functional machine learning platform development for better healthcare and precision medicine. Database. 2020;2020:baaaa010. PMC7078068 32185396 · DOI · Paper page
  7. [7]Shoghli A, Darvish M, Sadeghian Y. Balancing innovation and privacy: ethical challenges in AI-driven healthcare. J Rev Med Sci. 2024;4(1):1–11.
  8. [8]Alowais SA, et al. Revolutionizing healthcare: the role of artificial intelligence in clinical practice. BMC Med Educ. 2023;23(1):689. 37740191 PMC10517477 · DOI · Paper page
  9. [9]Edison G. Transforming medical decision-making: A comprehensive review of AI’s impact on diagnostics and treatment. BULLET. 2023;2(4):1121–33.
  10. [10]Khalid H, et al. A comparative systematic literature review on knee bone reports from MRI, x-rays and CT scans using deep learning and machine learning methodologies. Diagnostics. 2020;10(8):518. 32722605 PMC7460189 · DOI
  11. [11]Kumar P, et al. Advanced artificial intelligence technologies transforming contemporary pharmaceutical research. Bioengineering. 2025;12(4):363. 40281723 PMC12024664 · DOI
  12. [12]Taye MM. Understanding of machine learning with deep learning: architectures, workflow, applications and future directions. Computers. 2023;12(5):91. · DOI
  13. [13]Sarker M. Revolutionizing healthcare the role of machine learning in the health sector. J Artif Intell General Sci (JAIGS) ISSN. 2024;2(1):36–61.
  14. [15]Miotto R, et al. Deep learning for healthcare: review, opportunities and challenges. Brief Bioinform. 2018;19(6):1236–46. 28481991 PMC6455466 · DOI · Paper page
  15. [16]Sarvamangala DR, Kulkarni RV. Convolutional neural networks in medical image understanding: a survey. Evol Intell. 2022;15(1):1–22. 33425040 PMC7778711 · DOI
  16. [17]Mienye ID, Swart TG, Obaido G. Recurrent neural networks: a comprehensive review of architectures, variants, and applications. Information. 2024;15(9):517. · DOI
  17. [19]Sarella PNK, Mangam VT. Ai-driven natural language processing in healthcare: transforming patient-provider communication. Indian J Pharm Pract. 2024. 10.5530/ijopp.17.1.4. · DOI
  18. [20]Singla, S., et al. Advancements in Natural Language Processing: BERT and Transformer-Based Models for Text Understanding. IEEE.
  19. [21]Pramanik B, et al. Beyond prediction: how generative AI is creating new healthcare realities. In: Revolutionizing Healthcare 50 the power of generative AI advancements in patient care through generative AI algorithms. Cham: Springer; 2025.
  20. [22]Lang O, et al. Using generative AI to investigate medical imagery models and datasets. EBioMedicine. 2024;1:102. PMC10993140 38565004
  21. [23]Zeng X, et al. Deep generative molecular design reshapes drug discovery. Cell Rep Med. 2022. 10.1016/j.xcrm.2022.100794. 36306797 PMC9797947 · DOI · Paper page
  22. [26]Moafa KMY, et al. Artificial intelligence for improved health management: application, uses, opportunities, and challenges-a systematic review. Egypt J Chem. 2024;67(13):865–80. · DOI
  23. [28]Friedman C, Elhadad N. Natural language processing in health care and biomedicine. In: Biomedical informatics: computer applications in health care and biomedicine. London: Springer; 2014.
  24. [32]Mulukuntla S, Venkata SP. AI-driven personalized medicine: assessing the impact of federal policies on advancing patient-centric care. EPH-Int J Med Health Sci. 2020;6(2):20–6.
  25. [33]Parekh A-DE, et al. Artificial intelligence (AI) in personalized medicine: AI-generated personalized therapy regimens based on genetic and medical history. Ann Med Surg. 2023;85(11):5831–3. PMC10617817 37915639 · DOI
  26. [34]Bhattamisra SK, et al. Artificial intelligence in pharmaceutical and healthcare research. Big Data Cogn Comput. 2023;7(1):10. · DOI
  27. [35]Quazi S. Artificial intelligence and machine learning in precision and genomic medicine. Med Oncol. 2022;39(8):120. 35704152 PMC9198206 · DOI
  28. [37]Jena B, et al. Brain tumor characterization using radiogenomics in artificial intelligence framework. Cancers (Basel). 2022;14(16):4052. 36011048 PMC9406706 · DOI
  29. [38]Alam MA, et al. The role of predictive analytics in early disease detection: a data-driven approach to preventive healthcare. Innov Eng J. 2024;1(01):105–23. · DOI
  30. [39]Alessa A, Faezipour M. A review of influenza detection and prediction through social networking sites. Theor Biol Med Model. 2018;15:1–27. 29386017 PMC5793414 · DOI
  31. [40]Srinivasan SM, Sharma V. Applications of AI in cardiovascular disease detection—A review of the specific ways in which AI is being used to detect and diagnose cardiovascular diseases. AI Dis Detect. 2025;1:123–46. · DOI
  32. [41]Khalifa M, Albadawy M. AI in diagnostic imaging: revolutionising accuracy and efficiency. Comput Methods Progr Biomed. 2024;5:100146.
  33. [42]Li X, et al. Role of artificial intelligence in medical image analysis: a review of current trends and future directions. J Med Biol Eng. 2024;44(2):231–43. · DOI
  34. [43]Megat Ramli PN, et al. A systematic review: the role of artificial intelligence in lung cancer screening in detecting lung nodules on chest X-rays. Diagnostics. 2025;15(3):246. 39941176 PMC11817343 · DOI
  35. [44]Litjens G, et al. A survey on deep learning in medical image analysis. Med Image Anal. 2017;42:60–88. 28778026 · DOI · Paper page
  36. [45]Kumar RR, Priyadarshi R. Denoising and segmentation in medical image analysis: a comprehensive review on machine learning and deep learning approaches. Multimedia Tools Appl. 2025;84(12):10817–75. · DOI
  37. [46]Zhu B, et al. Image reconstruction by domain-transform manifold learning. Nature. 2018;555(7697):487–92. 29565357 · DOI · Paper page
  38. [48]Schutte K, et al. An artificial intelligence model predicts the survival of solid tumour patients from imaging and clinical data. Eur J Cancer. 2022;174:90–8. 35985252 · DOI
  39. [49]Wang X, et al. A pathology foundation model for cancer diagnosis and prognosis prediction. Nature. 2024;634(8035):970–8. 39232164 PMC12186853 · DOI · Paper page
  40. [50]McKinney SM, et al. International evaluation of an AI system for breast cancer screening. Nature. 2020;577(7788):89–94. 31894144 · DOI · Paper page
  41. [51]Gupta U, et al. The contribution of artificial intelligence to drug discovery: Current progress and prospects for the future. Microbial Data Intell Comput Techn Sustain Comput. 2024;1:1–23.
  42. [52]Fahim YA, Hasani IW, Ragab WM. Promising biomedical applications using superparamagnetic nanoparticles. Eur J Med Res. 2025;30(1):441. 40452035 PMC12128481 · DOI
  43. [53]Murugan NA, et al. Artificial intelligence in virtual screening: models versus experiments. Drug Discov Today. 2022;27(7):1913–23. 35597513 · DOI
  44. [54]Wong F, et al. Discovery of a structural class of antibiotics with explainable deep learning. Nature. 2024;626(7997):177–85. 38123686 PMC10866013 · DOI
  45. [55]Lopez JS, Banerji U. Combine and conquer: challenges for targeted therapy combinations in early phase trials. Nat Rev Clin Oncol. 2017;14(1):57–66. 27377132 PMC6135233 · DOI · Paper page
  46. [56]Smith GF. Artificial intelligence in drug safety and metabolism. In: Artificial Intelligence in Drug Design. Springer; 2021. p. 483–501. 34731484
  47. [57]Zhu H. Big data and artificial intelligence modeling for drug discovery. Annu Rev Pharmacol Toxicol. 2020;60(1):573–89. 31518513 PMC7010403 · DOI · Paper page
  48. [58]Ciallella HL, Zhu H. Advancing computational toxicology in the big data era by artificial intelligence: data-driven and mechanism-driven modeling for chemical toxicity. Chem Res Toxicol. 2019;32(4):536–47. 30907586 PMC6688471 · DOI · Paper page
  49. [59]Chan HCS, et al. Advancing drug discovery via artificial intelligence. Trends Pharmacol Sci. 2019;40(8):592–604. 31320117 · DOI · Paper page
  50. [60]Petitjean, M. and A.C. Camproux, In Silico Medicinal Chemistry: Computational Methods to Support Drug Design. Edited by Nathan Brown. Wiley Online Library. 2016
  51. [61]Pereira JC, Caffarena ER, Dos Santos CN. Boosting docking-based virtual screening with deep learning. J Chem Inf Model. 2016;56(12):2495–506. 28024405 · DOI · Paper page
  52. [63]Abbasi N, Hussain HK. Integration of artificial intelligence and smart technology: AI-driven robotics in surgery: precision and efficiency. J Artif Intell General Sci. 2024;5(1):381–90.
  53. [64]Pinto-Coelho L. How artificial intelligence is shaping medical imaging technology: a survey of innovations and applications. Bioengineering. 2023;10(12):1435. 38136026 PMC10740686 · DOI
  54. [65]Wah JNK. Revolutionizing surgery: AI and robotics for precision, risk reduction, and innovation. J Robot Surg. 2025;19(1):1–15. 39776281 · DOI
  55. [66]Khajeh E, et al. Outcomes of robot-assisted surgery in rectal cancer compared with open and laparoscopic surgery. Cancers. 2023;15(3):839. 36765797 PMC9913667 · DOI
  56. [67]Hopkins MB, et al. Comparing pathologic outcomes for robotic versus laparoscopic surgery in rectal cancer resection: a propensity adjusted analysis of 7616 patients. Surg Endosc. 2020;34(6):2613–22. 31346754 PMC8117669 · DOI
  57. [69]Kamarajah SK, et al. Robotic versus conventional laparoscopic pancreaticoduodenectomy a systematic review and meta-analysis. Eur J Surg Oncol. 2020;46(1):6–14. 31409513 · DOI
  58. [70]Meziane F, et al. Intelligent systems in manufacturing: current developments and future prospects. Integr Manuf Syst. 2000;11(4):218–38. · DOI
  59. [71]Fahim YA, et al. Biomedical and environmental applications via nanobiocatalysts and enzyme immobilization. Eur J Med Res. 2025;30(1):505. 40544317 PMC12181844 · DOI
  60. [72]Kabra A, et al. Computational fluid dynamics used by mixing vessels for predicting hydrodynamic behaviour of mixture: an overview. Mater Today Proc. 2021;47:2305–9. · DOI
  61. [73]Rantanen J, Khinast J. The future of pharmaceutical manufacturing sciences. J Pharm Sci. 2015;104(11):3612–38. 26280993 PMC4973848 · DOI
  62. [74]Steiner S, et al. Organic synthesis in a modular robotic system driven by a chemical programming language. Science. 2019;363(6423):eaav2211. 30498165 · DOI
  63. [75]Faure A, York P, Rowe RC. Process control and scale-up of pharmaceutical wet granulation processes: a review. Eur J Pharm Biopharm. 2001;52(3):269–77. 11677069 · DOI
  64. [76]Landin M. Artificial intelligence tools for scaling up of high shear wet granulation process. J Pharm Sci. 2017;106(1):273–7. 27816264 · DOI
  65. [78]Paul D, et al. Artificial intelligence in drug discovery and development. Drug Discov Today. 2021;26(1):80–93. 33099022 PMC7577280 · DOI · Paper page
  66. [79]Luo M, et al. Micro-/nanorobots at work in active drug delivery. Adv Funct Mater. 2018;28(25):1706100. · DOI
  67. [80]Das T, Sultana S. Multifaceted applications of micro/nanorobots in pharmaceutical drug delivery systems: a comprehensive review. Future J Pharm Sci. 2024;10(1):2. · DOI
  68. [81]Kazi RNA, et al. Nanomedicine: the effective role of nanomaterials in healthcare from diagnosis to therapy. Pharmaceutics. 2025;17(8):987. 40871010 PMC12389108 · DOI
  69. [82]Fu J, Yan H. Controlled drug release by a nanorobot. Nat Biotechnol. 2012;30(5):407–8. 22565965 · DOI
  70. [83]Sutradhar KB, Sumi CD. Implantable microchip: the futuristic controlled drug delivery system. Drug Deliv. 2016;23(1):1–11. 24758139 · DOI
  71. [84]Rasa AR. Artificial intelligence and its revolutionary role in physical and mental rehabilitation: a review of recent advancements. BioMed Res Int. 2024;2024(1):9554590. 39720127 PMC11668540 · DOI
  72. [85]Nizamis K, et al. Converging robotic technologies in targeted neural rehabilitation: a review of emerging solutions and challenges. Sensors. 2021;21(6):2084. 33809721 PMC8002299 · DOI
  73. [86]Anderson D. Artificial intelligence and applications in PM&R. Am J Phys Med Rehabil. 2019;98(11):e128–9. 30839314 · DOI
  74. [87]Khalid UB, et al. Impact of AI-powered solutions in rehabilitation process: recent improvements and future trends. Int J Gen Med. 2024. 10.2147/IJGM.S453903. 38495919 PMC10944308 · DOI
  75. [89]Jansen O, et al. Hybrid assistive limb exoskeleton HAL in the rehabilitation of chronic spinal cord injury: proof of concept; the results in 21 patients. World Neurosurg. 2018;110:e73–8. 29081392 · DOI
  76. [90]Kawamoto H, Sankai Y. Power assist method based on phase sequence and muscle force condition for HAL. Adv Robotics. 2005;19(7):717–34. · DOI
  77. [91]Louie DR, Eng JJ. Powered robotic exoskeletons in post-stroke rehabilitation of gait: a scoping review. J Neuroeng Rehabil. 2016;13:1–10. 27278136 PMC4898381 · DOI
  78. [92]Al Kuwaiti A, et al. A review of the role of artificial intelligence in healthcare. J Pers Med. 2023;13(6):951. 37373940 PMC10301994 · DOI · Paper page
  79. [93]Qiu H, et al. Applications of artificial intelligence in screening, diagnosis, treatment, and prognosis of colorectal cancer. Curr Oncol. 2022;29(3):1773–95. 35323346 PMC8947571 · DOI
  80. [94]Sovich JL, Sartor Z, Misra S. Developments in screening tests and strategies for colorectal cancer. BioMed Res Int. 2015;2015(1):326728. 26504799 PMC4609363
  81. [95]Rompianesi G, et al. Artificial intelligence in the diagnosis and management of colorectal cancer liver metastases. World J Gastroenterol. 2022;28(1):108. 35125822 PMC8793013 · DOI
  82. [96]Davri A, et al. Deep learning on histopathological images for colorectal cancer diagnosis: a systematic review. Diagnostics. 2022;12(4):837. 35453885 PMC9028395 · DOI
  83. [97]Deepali N, Goel, Khandnor P. Advances in AI-based genomic data analysis for cancer survival prediction. Multim Tools Appl. 2024;1:1–28.
  84. [98]Yamada M, et al. Development of a real-time endoscopic image diagnosis support system using deep learning technology in colonoscopy. Sci Rep. 2019;9(1):14465. 31594962 PMC6783454 · DOI
  85. [99]Wan N, et al. Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA. BMC Cancer. 2019;19(1):832. 31443703 PMC6708173 · DOI
  86. [100]Rathore S, et al. Novel structural descriptors for automated colon cancer detection and grading. Comput Methods Programs Biomed. 2015;121(2):92–108. 26094859 · DOI
  87. [101]Giaquinto AN, et al. Breast cancer statistics, 2022. CA Cancer J Clin. 2022;72(6):524–41. 36190501
  88. [102]Filho OM, et al. Impact of HER2 heterogeneity on treatment response of early-stage HER2-positive breast cancer: phase II neoadjuvant clinical trial of T-DM1 combined with pertuzumab. Cancer Discov. 2021;11(10):2474–87. 33941592 PMC8598376 · DOI
  89. [103]Dowling GP, et al. Predictive value of pretreatment circulating inflammatory response markers in the neoadjuvant treatment of breast cancer: meta-analysis. Br J Surg. 2024;111(5):znae132. 38801441 PMC11129713 · DOI
  90. [104]Ji J, et al. Artificial intelligence-based pathology to assist prediction of neoadjuvant therapy responses for breast cancer. Cancer Med. 2025;14(15):e71132. 40762329 PMC12322828 · DOI
  91. [105]Cruz-Roa A, et al. Accurate and reproducible invasive breast cancer detection in whole-slide images: a deep learning approach for quantifying tumor extent. Sci Rep. 2017;7(1):46450. 28418027 PMC5394452 · DOI
  92. [106]Han Z, et al. Breast cancer multi-classification from histopathological images with structured deep learning model. Sci Rep. 2017;7(1):4172. 28646155 PMC5482871 · DOI
  93. [107]Luo J, et al. A deep-learning-based clinical risk stratification for overall survival in adolescent and young adult women with breast cancer. J Cancer Res Clin Oncol. 2023;149(12):10423–33. 37277578 PMC11798295 · DOI
  94. [108]Huang CY, et al. Deep-learning model to improve histological grading and predict upstaging of atypical ductal hyperplasia/ductal carcinoma in situ on breast biopsy. Histopathology. 2024;84(6):983–1002. 38288642 · DOI
  95. [109]Siegel RL, et al. Cancer statistics, 2022. CA Cancer J Clin. 2022. 10.3322/caac.21708.36346402 · DOI · Paper page
  96. [110]Yan W, et al. Applicability analysis of immunotherapy for lung cancer patients based on deep learning. Methods. 2022;205:149–56. 35809770 · DOI
  97. [111]Weber D, et al. Accurate detection of tumor-specific gene fusions reveals strongly immunogenic personal neo-antigens. Nat Biotechnol. 2022;40(8):1276–84. 35379963 PMC7613288 · DOI
  98. [113]Ashraf SF, et al. Predicting benign, preinvasive, and invasive lung nodules on computed tomography scans using machine learning. J Thorac Cardiovasc Surg. 2022;163(4):1496–505. 33726909 · DOI
  99. [114]Wang S, et al. Artificial intelligence in lung cancer pathology image analysis. Cancers. 2019;11(11):1673. 31661863 PMC6895901 · DOI
  100. [115]Zhong Y, et al. Deep learning for prediction of N2 metastasis and survival for clinical stage I non–small cell lung cancer. Radiology. 2022;302(1):200–11. 34698568 · DOI
  101. [116]Prelaj A, et al. Machine learning using real-world and translational data to improve treatment selection for NSCLC patients treated with immunotherapy. Cancers (Basel). 2022;14(2):435. 35053597 PMC8773718 · DOI
  102. [117]Bacha A, Shah HH. Ai-powered virtual health assistants: transforming patient care and engagement. Glob Insights Artif Intell Comput. 2025;1(1):15–30. · DOI
  103. [121]Miner AS, et al. Smartphone-based conversational agents and responses to questions about mental health, interpersonal violence, and physical health. JAMA Intern Med. 2016;176(5):619–25. 26974260 PMC4996669 · DOI · Paper page
  104. [122]Secara I-A, Hordiiuk D. Personalized health monitoring systems: integrating wearable and AI. J Intell Learn Syst Appl. 2024;16(2):44–52.
  105. [123]Kang HS, Exworthy M. Wearing the future—wearables to empower users to take greater responsibility for their health and care: scoping review. JMIR Mhealth Uhealth. 2022;10(7):e35684. 35830222 PMC9330198 · DOI
  106. [124]Lu L, et al. Wearable health devices in health care: narrative systematic review. JMIR Mhealth Uhealth. 2020;8(11):e18907. 33164904 PMC7683248 · DOI · Paper page
  107. [125]George ASH, Shahul A, George AS. Wearable sensors: A new way to track health and wellness. Partn Universal Int Innov J. 2023;1(4):15–34.
  108. [126]Salinari A, et al. The application of digital technologies and artificial intelligence in healthcare: an overview on nutrition assessment. Dis. 2023;11(3):97. PMC10366918 37489449
  109. [127]Sorrentino FS, et al. Novel approaches for early detection of retinal diseases using artificial intelligence. J Pers Med. 2024;14(7):690. 39063944 PMC11278069 · DOI
  110. [128]Liu Y, et al. Artificial intelligence-based breast cancer nodal metastasis detection: insights into the black box for pathologists. Arch Pathol Lab Med. 2019;143(7):859–68. 30295070 · DOI
  111. [129]Qureshi A. Robotic surgery: enhancing precision in complex procedures. Rev J Neurol Med Sci Rev. 2024;2(3):28–36.
  112. [130]Ismail AR, et al. Utilising VGG-16 of convolutional neural network for medical image classification. Int J Percept Cognit Comput. 2024;10(1):113–8.
  113. [132]dos Santos FM, et al. Comparing artificial intelligence AI-rad companion chest CT vs experts on emphysema, lung nodules, thoracic aorta and thoracic spine. Acta Radiológica Portuguesa. 2024;36(1):6–11.
  114. [133]Desai D, et al. Review of AlphaFold 3: transformative advances in drug design and therapeutics. Cureus. 2024;16:7. PMC11292590 39092344
  115. [134]Yang H-C, et al. Deep learning for automated segmentation of brain edema in meningioma after radiosurgery. BMC Med Imaging. 2025;25(1):130. 40264119 PMC12016358 · DOI
  116. [135]Liu C, et al. Using artificial intelligence (Watson for Oncology) for treatment recommendations amongst Chinese patients with lung cancer: feasibility study. J Med Internet Res. 2018;20(9):e11087. 30257820 PMC6231834 · DOI
  117. [136]Zhang Y, et al. Lung nodule detectability of artificial intelligence-assisted CT image reading in lung cancer screening. Curr Med Imaging Rev. 2022;18(3):327–34. 34365951 · DOI
  118. [137]Tayefi M, et al. Challenges and opportunities beyond structured data in analysis of electronic health records. Wiley Interdiscip Rev Comput Stat. 2021;13(6):e1549. · DOI
  119. [138]Ortega-Calvo AS, et al. Aimdp: an artificial intelligence modern data platform. Use case for Spanish national health service data silo. Future Gener Comput Syst. 2023;143:248–64. · DOI
  120. [139]Williams E, et al. A standardized clinical data harmonization pipeline for scalable AI application deployment (FHIR-DHP): validation and usability study. JMIR Med Inform. 2023;11:e43847. 36943344 PMC10131740 · DOI
  121. [140]Sinaci AA, et al. A data transformation methodology to create findable, accessible, interoperable, and reusable health data: software design, development, and evaluation study. J Med Internet Res. 2023;25:e42822. 36884270 PMC10034606 · DOI
  122. [141]Cai Q, et al. A survey on multimodal data-driven smart healthcare systems: approaches and applications. IEEE Access. 2019;7:133583–99. · DOI
  123. [142]Althati C, Tomar M, Shanmugam L. Enhancing data integration and management: the role of AI and machine learning in modern data platforms. J Artif Intell General Sci. 2024;2(1):220–32.
  124. [143]Pashazadeh A, Navimipour NJ. Big data handling mechanisms in the healthcare applications: a comprehensive and systematic literature review. J Biomed Inform. 2018;82:47–62. 29655946 · DOI
  125. [144]Kalia K, Gupta N. Analysis of hadoop mapreduce scheduling in heterogeneous environment. Ain Shams Eng J. 2021;12(1):1101–10. · DOI
  126. [145]Khalil WA, Torkey H, Attiya G. Survey of Apache Spark optimized job scheduling in Big Data. Int J Ind Sustain Dev. 2020;1(1):39–48.
  127. [146]Surianarayanan C, et al. A survey on optimization techniques for edge artificial intelligence (AI). Sensors. 2023;23(3):1279. 36772319 PMC9919555 · DOI · Paper page
  128. [147]Hua H, et al. Edge computing with artificial intelligence: a machine learning perspective. ACM Comput Surv. 2023;55(9):1–35. · DOI
  129. [148]Khanh QV, et al. An integrating computing framework based on edge-fog-cloud for internet of healthcare things applications. Internet Things. 2023;23:100907. · DOI
  130. [149]Wani NA, Kumar R, Bedi J. Deepxplainer: an interpretable deep learning based approach for lung cancer detection using explainable artificial intelligence. Comput Methods Programs Biomed. 2024;243:107879. 37897989 · DOI
  131. [150]Kök I, et al. Explainable artificial intelligence (XAI) for internet of things: a survey. IEEE Internet Things J. 2023;10(16):14764–79. · DOI
  132. [151]Band SS, et al. Application of explainable artificial intelligence in medical health: a systematic review of interpretability methods. Inf Med Unlocked. 2023;40:101286. · DOI
  133. [152]Liu B. Lifelong machine learning: a paradigm for continuous learning. Front Comput Sci. 2017;11(3):359–61. · DOI
  134. [153]Feng J, et al. Clinical artificial intelligence quality improvement: towards continual monitoring and updating of AI algorithms in healthcare. NPJ Digit Med. 2022;5(1):66. 35641814 PMC9156743 · DOI · Paper page
  135. [156]Prabhu, A., et al., Online continual learning without the storage constraint. arXiv preprint arXiv:2305.09253, 2023. · arXiv
  136. [157]Hu Y, et al. Artificial intelligence security: threats and countermeasures. ACM Comput Surv. 2021;55(1):1–36. · DOI · Paper page
  137. [158]Qayyum A, et al. Secure and robust machine learning for healthcare: a survey. IEEE Rev Biomed Eng. 2020;14:156–80. 32746371 · DOI · Paper page
  138. [159]Goktas P, Grzybowski A. Shaping the future of healthcare: ethical clinical challenges and pathways to trustworthy AI. J Clin Med. 2025;14(5):1605. 40095575 PMC11900311 · DOI · Paper page
  139. [160]Ueda D, et al. Fairness of artificial intelligence in healthcare: review and recommendations. Jpn J Radiol. 2024;42(1):3–15. 37540463 PMC10764412 · DOI · Paper page
  140. [161]Pagano TP, et al. Bias and unfairness in machine learning models: a systematic review on datasets, tools, fairness metrics, and identification and mitigation methods. Big Data Cogn Comput. 2023;7(1):15. · DOI
  141. [162]Kucukkaya A, et al. Equality, diversity, and inclusion in artificial intelligence-driven healthcare chatbots addressing challenges and shaping strategies. Eur J Cardiovasc Nurs. 2025;1:105. 40455916
  142. [163]Gao X, et al. Artificial intelligence applications in smart healthcare: a survey. Futur Int. 2024;16(9):308. · DOI
  143. [166]Amjad A, Kordel P, Fernandes G. A review on innovation in healthcare sector (telehealth) through artificial intelligence. Sustainability. 2023;15(8):6655. · DOI
  144. [167]Uschnig C, et al. Tele-ultrasound in the era of COVID-19: a practical guide. Ultrasound Med Biol. 2022;48(6):965–74. 35317949 PMC8743597 · DOI
  145. [168]Rao DP, et al. Evaluation of an offline, artificial intelligence system for referable glaucoma screening using a smartphone-based fundus camera: a prospective study. Eye. 2024;38(6):1104–11. 38092938 PMC11009383 · DOI
  146. [169]Wang C-H, et al. Lightweight deep learning: an overview. IEEE Consum Electron Mag. 2022;13(4):51–64. · DOI
  147. [171]Ellwood-Lowe ME, et al. Time-varying effects of income on hippocampal volume trajectories in adolescent girls. Dev Cogn Neurosci. 2018;30:41–50. 29275097 PMC5963716 · DOI
  148. [173]Neto, E.C., Using permutations to detect, quantify and correct for confounding in machine learning predictions. arXiv preprint arXiv:1805.07465, 2018. · arXiv
  149. [174]He H, Garcia EA. Learning from imbalanced data. IEEE Trans Knowl Data Eng. 2009;21(9):1263–84. · DOI · Paper page
  150. [175]Alsheibani, S.A., D. Cheung, and D. Messom, Factors inhibiting the adoption of artificial intelligence at organizational level: A preliminary investigation. Twenty-fifth Americas Conference on Information Systems, Cancun. 2019.
  151. [179]Unanah OV, Aidoo EM. The potential of AI technologies to address and reduce disparities within the healthcare system by enabling more personalized and efficient patient engagement and care management. World J Adv Res Rev. 2025;25(2):2643–64. · DOI
  152. [181]Chen RJ, et al. Algorithmic fairness in artificial intelligence for medicine and healthcare. Nat Biomed Eng. 2023;7(6):719–42. 37380750 PMC10632090 · DOI · Paper page
  153. [182]Cross JL, Choma MA, Onofrey JA. Bias in medical AI: implications for clinical decision-making. PLoS Digit Health. 2024;3(11):e0000651. 39509461 PMC11542778 · DOI · Paper page
  154. [183]Jurczuk M, Suprunowicz M. Consent in data privacy: a general comparison of GDPR and HIPAA. Przegląd Prawniczy Uniwersytetu im Adam Mickiewicza. 2024;16:173–94. · DOI
  155. [184]Addario BJ, et al. Patient value: perspectives from the advocacy community. Health Expect. 2018;21(1):57–63. 28940536 PMC5750698 · DOI
  156. [185]Ali H. Artificial intelligence in multi-omics data integration: Advancing precision medicine, biomarker discovery and genomic-driven disease interventions. Int J Sci Res Arch. 2023;8(1):1012–30. · DOI
  157. [186]Ali H. Quantum computing and AI in healthcare: Accelerating complex biological simulations, genomic data processing, and drug discovery innovations. World J Adv Res Rev. 2023;20(2):1466–84. · DOI
  158. [187]Reddy S. Global harmonization of artificial intelligence-enabled software as a medical device regulation: addressing challenges and unifying standards. Mayo Clinic Proc Digit Health. 2025. 10.1016/j.mcpdig.2024.100191. PMC11975980 40207007 · DOI
  159. [189]Ngcobo M. The ethics and law of medical AI in South Africa: balancing innovation with responsibility. SAMJ S Afr Med J. 2025;115(5B):75–9. 41378646
  160. [191]Rehm HL, et al. GA4GH: international policies and standards for data sharing across genomic research and healthcare. Cell Genom. 2021. 10.1016/j.xgen.2021.100029. 35072136 PMC8774288 · DOI

Cited by

Sorted by citations

Authors
Fahim, Y. A., Hasani, I. W., Kabba, S., & Ragab, W. M.
Affiliations
  • Galala University (EG)
  • Al Andalus University (SY)
Corresponding author
Fahim, Yosri A.
Venue
European Journal of Medical Research
Published
2025-09-23
Volume
30
Issue
1
Pages
848-848
ISSN
  • 0949-2321 (ISSN-L)
  • 2047-783X
OpenAlex
W4414413410
Cited by
329
References
20
Citations by year
2026: 317 · 2025: 12
FWCI
19.45
Type
journal article
Language
en
Open access
Locations
  • European journal of medical research (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • PubMed Central (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Galala University
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
  • Physical Sciences › Computer Science › Artificial Intelligence › Artificial Intelligence Applications
Keywords
artificial intelligence in healthcare, clinical applications of AI, medical diagnostics, personalized medicine, drug discovery, predictive analytics, telemedicine, wearable health technology, mobile diagnostics, resource-limited settings, data privacy, algorithmic bias, model interpretability, AI regulation, electronic health records, diagnostic imaging, genomic data
MeSH terms
Artificial Intelligence, Delivery of Health Care, Humans, Telemedicine, Precision Medicine

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review