The DOI matches its Crossref record; 258 of the 259 references it cites were found in a registry or an index.
Nitric oxide and redox mechanisms in the immune response
Open accessAbstract
The role of redox molecules, such as NO and ROS, as key mediators of immunity has recently garnered renewed interest and appreciation. To regulate immune responses, these species trigger the eradication of pathogens on the one hand and modulate immunosuppression during tissue-restoration and wound-healing processes on the other. In the acidic environment of the phagosome, a variety of RNS and ROS is produced, thereby providing a cauldron of redox chemistry, which is the first line in fighting infection. Interestingly, fluctuations in the levels of these same reactive intermediates orchestrate other phases of the immune response. NO activates specific signal transduction pathways in tumor cells, endothelial cells, and monocytes in a concentration-dependent manner. As ROS can react directly with NO-forming RNS, NO bioavailability and therefore, NO response(s) are changed. The NO/ROS balance is also important during Th1 to Th2 transition. In this review, we discuss the chemistry of NO and ROS in the context of antipathogen activity and immune regulation and also discuss similarities and differences between murine and human production of these intermediates.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“nNOS and eNOS, which are expressed constitutively, produce a low level of NO for short periods (seconds to minutes).447”
From Role of neuroinflammation in neurodegeneration development (2023) · cites this paper as [447]
In the citing paper
“At present, three types of NOS have been identified, including neuronal NOS (nNOS, also named as NOS1), endothelial NOS (eNOS, also named as NOS3), and inducible NOS (iNOS, also named as NOS2).447”
From Role of neuroinflammation in neurodegeneration development (2023) · cites this paper as [447]
In the citing paper
“Intracellular communication and immune response are mediated by at least five classes of endogenously generated reactive small molecules (Figure 1): nitric oxide (NO) and reactive nitrogen oxide species (RNS), reactive oxygen species (ROS), eicosanoids and reactive lipid species (formed by oxidation of fatty acids), a variety of sulfur-based species such as hydrogen sulfide (H2S), thiols and disul”
From Signaling and stress: The redox landscape in NOS2 biology (2015) · cites this paper as [3]
In the citing paper
“An additional mechanism for IL-10 production is through NO-dependent increases of COX2 [3, 57]].”
From Signaling and stress: The redox landscape in NOS2 biology (2015) · cites this paper as [3]
In the citing paper
“In chronic disease, involving extended exposure to pathogens or particulates such as plaques in the brain or following a critical mutation, wound healing processes persist and can lead to fibrosis or tumor growth [3].”
From Signaling and stress: The redox landscape in NOS2 biology (2015) · cites this paper as [3]
In the citing paper
“These molecules can act as sensors to steer signaling cascades during inflammation, for example from a T helper (Th) 1 to a Th2 cytokine response [3, 87].”
From Signaling and stress: The redox landscape in NOS2 biology (2015) · cites this paper as [3]
In the citing paper
“In the phagosome, iron deposition facilitates the sterilization process in conjunction with ROS and nitrite [3].”
From Signaling and stress: The redox landscape in NOS2 biology (2015) · cites this paper as [3]
In the citing paper
“Lysis of Staphylococcus bacteria involves the sequential exposure to respiratory burst followed by •NO exposure [126].”
From The Role of Reactive Species on Innate Immunity (2022) · cites this paper as [126]
In the citing paper
“•NO and RNS eradicate bacteria by nitrosylation and oxidation of bacterial macromolecules [126].”
From The Role of Reactive Species on Innate Immunity (2022) · cites this paper as [126]
In the citing paper
“The •NO/ROS balance is also important during the transition from Th1 to Th2 [125,126].”
From The Role of Reactive Species on Innate Immunity (2022) · cites this paper as [126]
In the citing paper
“Recognition of bacteria by macrophages leads to ROS production in different cellular compartments, where they fulfill different antibacterial functions.”
From Functions of ROS in Macrophages and Antimicrobial Immunity (2021) · cites this paper as [234]
Citations
Cites
Free radicals in biology and medicine
Gutteridge, J. M. C. (1991) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178
Nitric oxide: physiology, pathophysiology, and pharmacology.
Moncada, S., Palmer, R. M., & Higgs, E. A. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06663-3 · Cited by 15,525
Free Radicals in Biology and Medicine
Land, E. J. (1990) · International Journal of Radiation Biology · doi:10.1080/09553009014552071 · Cited by 4,871
Function and Activation of NF-kappaB in the Immune System
Baeuerle, P. A., & Henkel, T. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.001041 · Cited by 4,745
Macrophage activation and polarization
Martinez, F. O. (2008) · Frontiers in Bioscience · doi:10.2741/2692 · Cited by 3,160
Nitric oxide: an endogenous modulator of leukocyte adhesion.
Kubes, P., Suzuki, M., & Granger, D. N. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.11.4651 · Cited by 3,036
Ren, G., Zhang, L., Zhao, X., Xu, G., Zhang, Y., Roberts, A. I., Zhao, R. C., & Shi, Y. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2007.11.014 · Cited by 2,101
Nitric oxide: A cytotoxic activated macrophage effector molecule
Hibbs, J. B., Taintor, R. R., Vavrin, Z., & Rachlin, E. M. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)80015-9 · Cited by 2,034
The JAK/STAT signaling pathway
Rawlings, J. S., Rosler, K. M., & Harrison, D. A. (2004) · Journal of Cell Science · doi:10.1242/jcs.00963 · Cited by 1,858
Stuehr, D. J., & Nathan, C. F. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.169.5.1543 · Cited by 1,744
Flagged first, then by citations
1 of the 259 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Williams, 1988, Nitrosation
- Rhee, 2000, Sci. STKE
Cited by
Sorted by citations
Items 201–300 of 752
Yuan, R., He, J., Huang, L., Du, L., Gao, H., Xu, Q., & Yang, S. (2020) · Journal of Immunology Research · doi:10.1155/2020/7502301 · Cited by 44
Tan, L., Wang, Y., Ai, G., Luo, C., Chen, H., Li, C., Zeng, H., Xie, J., Chen, J., & Su, Z. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.105802 · Cited by 45
Acid Sphingomyelinase-Ceramide System in Bacterial Infections
Li, C., Wang, A., Wu, Y., Gulbins, E., Grassmé, H., & Zhao, Z. (2019) · Cellular Physiology and Biochemistry · doi:10.33594/000000021 · Cited by 43
Sowers, M. L., Tang, H. R., Singh, V. K., Khan, A., Mishra, A., Restrepo, B. I., Jagannath, C., & Zhang, K. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102418 · Cited by 45
Applications for nitric oxide in halting proliferation of tumor cells
Reynolds, M. M., Witzeling, S. D., Damodaran, V. B., Medeiros, T. N., Knodle, R. D., Edwards, M. A., Lookian, P. P., & Brown, M. A. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.01.041 · Cited by 43
A Substrate Trapping Approach Identifies Proteins Regulated by Reversible S-nitrosylation
Ben-Lulu, S., Ziv, T., Admon, A., Weisman-Shomer, P., & Benhar, M. (2014) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m114.038166 · Cited by 42
Weil’s Disease—Immunopathogenesis, Multiple Organ Failure, and Potential Role of Gut Microbiota
Petakh, P., Isevych, V., Kamyshnyi, O., & Oksenych, V. (2022) · Biomolecules · doi:10.3390/biom12121830 · Cited by 42
Souza, P. R., & Norling, L. V. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.05.072 · Cited by 42
Should perioperative immunonutrition for elective surgery be the current standard of care?: Table 1.
Bharadwaj, S., Trivax, B., Tandon, P., Alkam, B., Hanouneh, I. A., & Steiger, E. (2016) · Gastroenterology report · doi:10.1093/gastro/gow008 · Cited by 40
Chen, C., Sun, B., Guan, W., Bi, Y., Li, P., Ma, J., Chen, F., Pan, Q., & Xie, Q. (2015) · Aquaculture · doi:10.1016/j.aquaculture.2015.08.005 · Cited by 39
The emerging role of gasotransmitters in the pathogenesis of tuberculosis
Chinta, K. C., Saini, V., Glasgow, J. N., Mazorodze, J. H., Rahman, M. A., Reddy, D., Lancaster, J. R., & Steyn, A. J. C. (2016) · Nitric Oxide · doi:10.1016/j.niox.2016.06.009 · Cited by 41
Kemp‐Harper, B. K., Horowitz, J. D., & Ritchie, R. H. (2016) · Drugs · doi:10.1007/s40265-016-0631-y · Cited by 39
Najman, K., Sadowska, A., & Hallmann, E. (2021) · Applied Sciences · doi:10.3390/app11020874 · Cited by 39
Jian, M., Chen, X., Liu, S., Liu, Y., Liu, Y., Wang, Q., & Tu, W. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170948 · Cited by 40
Andonova, M., & Urumova, V. (2013) · Comparative Immunology Microbiology and Infectious Diseases · doi:10.1016/j.cimid.2013.03.003 · Cited by 38
Monocytes enhance neutrophil‐induced blister formation in an ex vivo model of bullous pemphigoid
de Graauw, E., Sitaru, C., Horn, M. P., Borradori, L., Yousefi, S., Simon, D., & Simon, H. (2017) · Allergy · doi:10.1111/all.13376 · Cited by 38
Hwang, D., Kang, M., Kang, C., & Kim, G. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4381 · Cited by 38
Zárate, L. V., Pontillo, C. A., Español, A. J., Miret, N. V., Chiappini, F., Cocca, C., Álvarez, L., de Pisarev, D. K., Sales, M. E., & Randi, A. S. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.115093 · Cited by 41
Neamat‐Allah, A. N. F., Mahsoub, Y. H., & Mahmoud, E. A. (2020) · Aquaculture Research · doi:10.1111/are.14910 · Cited by 38
McMahon, D. B., Kuek, L. E., Johnson, M. E., Johnson, P. O., Horn, R. L. J., Carey, R. M., Adappa, N. D., Palmer, J. N., & Lee, R. J. (2021) · Cell Calcium · doi:10.1016/j.ceca.2021.102499 · Cited by 38
Akram, M., Kim, K.-A., Kim, E. S., Shin, Y., Noh, D., Kim, E., Kim, J., Majid, A., Chang, S., Kim, J., et al. (2016) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2016.06.029 · Cited by 40
mNos2Deletion and HumanNOS2Replacement in Alzheimer Disease Models
Colton, C. A., Wilson, J. G., Everhart, A. L., Wilcock, D. M., Puoliväli, J. T., Heikkinen, T., Oksman, J., Jääskeläinen, O., Lehtimäki, K. K., Laitinen, T., et al. (2014) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0000000000000094 · Cited by 37
Self-citationNitric Oxide and Immune Responses in Cancer: Searching for New Therapeutic Strategies
Sahebnasagh, A., Saghafi, F., Negintaji, S., Hu, T., Shabani-Borujeni, M., Safdari, M., Ghaleno, H. R., Miao, L., Qi, Y., Wang, M., et al. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867328666210707194543 · Cited by 39
Nitric oxide controls shoot meristem activity via regulation of DNA methylation
Zeng, J., Zhao, X., Liang, Z., Hidalgo, I., Gebert, M., Fan, P., Wenzl, C., Gornik, S. G., & Lohmann, J. U. (2023) · Nature Communications · doi:10.1038/s41467-023-43705-1 · Cited by 36
Hu, W., Wu, L., Qiang, Q., Ji, L., Wang, X., Luo, H., Wu, H., Jiang, Y., Wang, G., & Shen, T. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.05.013 · Cited by 36
Zhou, Y. Y., Tao, H., Wang, A., Zhong, Z., Wu, X., Wang, M., Bian, Z., Wang, S., & Wang, Y. (2019) · Chinese Medicine · doi:10.1186/s13020-019-0224-2 · Cited by 36
Park, C., Lee, H., Hong, S. H., Molagoda, I. M. N., Jeong, J.-W., Jin, C., Kim, G., Choi, S. H., Hong, S. H., & Choi, Y. H. (2021) · International Journal of Medical Sciences · doi:10.7150/ijms.59169 · Cited by 36
Skeletal Muscle Nitrate as a Regulator of Systemic Nitric Oxide Homeostasis
Piknova, B., Schechter, A. N., Park, J. W., Vanhatalo, A., & Jones, A. M. (2021) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000272 · Cited by 38
Wang, Z., Lambden, S., Taylor, V., Sujkovic, E., Nandi, M., Tomlinson, J. A. P., Dyson, A., McDonald, N. Q., Caddick, S., Singer, M., et al. (2014) · Biochemical Journal · doi:10.1042/bj20131666 · Cited by 36
Switzer, C., Ridnour, L. A., Cheng, R. Y. S., Heinecke, J. L., Burke, A. J., Glynn, S. A., Ambs, S., & Wink, D. A. (2012) · Forum on Immunopathological Diseases and Therapeutics · doi:10.1615/forumimmundisther.2012006108 · Cited by 38
Self-citationDetermining Roles of Accessory Genes in Denitrification by Mutant Fitness Analyses
Vaccaro, B. J., Thorgersen, M. P., Lancaster, W. A., Price, M. N., Wetmore, K. M., Poole, F. L., Deutschbauer, A. M., Arkin, A. P., & Adams, M. W. W. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.02602-15 · Cited by 36
Nitric oxide regulates cell behavior on an interactive cell‐derived extracellular matrix scaffold
Xing, Q., Zhang, L., Redman, T., Qi, S., & Zhao, F. (2015) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35524 · Cited by 35
Midgut immune responses induced by bacterial infection in the silkworm, Bombyx mori
Zhang, L., Wang, Y., & Lu, Z. (2015) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b1500060 · Cited by 35
Hoos, M. D., Vitek, M. P., Ridnour, L. A., Wilson, J. G., Jansen, M., Everhart, A. L., Wink, D. A., & Colton, C. A. (2014) · Molecular Neurodegeneration · doi:10.1186/1750-1326-9-50 · Cited by 38
Self-citationTranscriptome profiling of the antiviral immune response in Atlantic cod macrophages
Eslamloo, K., Xue, X., Booman, M., Smith, N. C. P., & Rise, M. L. (2016) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2016.05.021 · Cited by 35
Kozłowska, L., Mizera, O., Gromadzińska, J., Janasik, B., Mikołajewska, K., Mróz, A., & Wąsowicz, W. (2020) · Antioxidants · doi:10.3390/antiox9070571 · Cited by 36
Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation
Lange, S. M., Nelen, M. I., Cohen, P., & Kulathu, Y. (2020) · Structure · doi:10.1016/j.str.2020.11.004 · Cited by 36
Massa, C. B., Liu, Z., Taylor, S., Pettit, A. P., Stakheyeva, M. N., Korotkova, E. I., Popova, V., Atochina‐Vasserman, E. N., & Gow, A. J. (2021) · Antioxidants · doi:10.3390/antiox10071111 · Cited by 37
Regulation of pancreatic β-cell survival by nitric oxide
Bedoya, F. J., Salguero‐Aranda, C., Cahuana, G. M., Tapia‐Limonchi, R., Soria, B., & Tejedo, J. R. (2012) · Islets · doi:10.4161/isl.19822 · Cited by 35
dos Reis, G. O., Vicente, G., de Carvalho, F. K., Heller, M., Micke, G. A., Pizzolatti, M. G., & Fröde, T. S. (2013) · Inflammopharmacology · doi:10.1007/s10787-013-0184-6 · Cited by 34
Muñoz‐Carrillo, J. L., Muñoz‐Escobedo, J. J., Tapia, C. H. M., Chávez-Ruvalcaba, F., & Moreno‐García, M. A. (2016) · Parasite Immunology · doi:10.1111/pim.12393 · Cited by 34
The Antiinflammatory Potential of Flavonoids
Catarino, M. D., Talhi, O., Rabahi, A., Silva, A. M. S., & Cardoso, S. M. (2016) · Studies in natural products chemistry · doi:10.1016/b978-0-444-63602-7.00003-5 · Cited by 34
Castiglione, A., Ciorba, A., Aimoni, C., Orioli, E., Zeri, G., Vigliano, M., & Gemmati, D. (2015) · BioMed Research International · doi:10.1155/2015/834736 · Cited by 33
The Breast Cancer Protooncogenes HER2, BRCA1 and BRCA2 and Their Regulation by the iNOS/NOS2 Axis
Lin, K., Baritaki, S., Vivarelli, S., Falzone, L., Scalisi, A., Libra, M., & Bonavida, B. (2022) · Antioxidants · doi:10.3390/antiox11061195 · Cited by 37
Huang, H., Yang, X., Li, W., Han, Q., Xu, Z., Xia, W., Wu, M., & Zhang, W. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.123816 · Cited by 33
Yan, J., Kuzhiumparambil, U., Bandodkar, A., Bandodkar, S., Dale, R. C., & Fu, S. (2020) · Developmental Medicine & Child Neurology · doi:10.1111/dmcn.14774 · Cited by 32
Wei, J., Fan, S., Liu, B.-S., Zhang, B., Su, J., & Yu, D. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.06.030 · Cited by 31
Copeland, D. C., Anderson, K. E., & Mott, B. M. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.00383-22 · Cited by 31
Clinical application of nasal nitric oxide measurement in pediatric airway diseases
Manna, A., Montella, S., Maniscalco, M., Maglione, M., & Santamaria, F. (2014) · Pediatric Pulmonology · doi:10.1002/ppul.23094 · Cited by 31
Changes in mammalian copper homeostasis during microbial infection
Culbertson, E. M., Khan, A. A., Muchenditsi, A., Lutsenko, S., Sullivan, D. J., Petris, M. J., Cormack, B. P., & Culotta, V. (2020) · Metallomics · doi:10.1039/c9mt00294d · Cited by 32
Salti, T., Braunstein, I., Haimovich, Y., Ziv, T., & Benhar, M. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103125 · Cited by 30
Nora, M. A.-A. (2018) · ISABB Journal of Food and Agricultural Sciences · doi:10.5897/isabb-jfas2017.0070 · Cited by 30
Regulation of macrophage subsets and cytokine production in leishmaniasis
Carneiro, M. B. H., Vaz, L. G., Afonso, L., Horta, M. F., & Vieira, L. Q. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155309 · Cited by 30
NO in Viral Infections: Role and Development of Antiviral Therapies
Sodano, F., Gazzano, E., Fruttero, R., & Lazzarato, L. (2022) · Molecules · doi:10.3390/molecules27072337 · Cited by 30
Üremi̇ş, M. M., Gültekin, S., Üremiş, N., Şafak, T., Çiğremiş, Y., Gül, M., Aydın, M., Zayman, E., & Türköz, Y. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02638-8 · Cited by 30
Lee, C., Wu, C. C., & Lin, T. L. (2015) · Archives of Virology · doi:10.1007/s00705-015-2612-y · Cited by 30
Błyszczuk, P., Berthonneche, C., Behnke, S., Glönkler, M., Moch, H., Pedrazzini, T., Lüscher, T. F., Eriksson, U., & Kania, G. (2012) · Cardiovascular Research · doi:10.1093/cvr/cvs317 · Cited by 30
Immune-enhancing activity of phosvitin by stimulating the production of pro-inflammatory mediator
Lee, J. H., Moon, S. H., Kim, H. S., Park, E., Ahn, D. U., & Paik, H. (2017) · Poultry Science · doi:10.3382/ps/pex205 · Cited by 30
Targeting Metabolic Pathways of Myeloid Cells Improves Cancer Immunotherapy
Li, J., Bolyard, C. M., Xin, G., & Li, Z. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.747863 · Cited by 31
Quantum Mechanical Modeling: A Tool for the Understanding of Enzyme Reactions
Náray‐Szabó, G., Oláh, J., & Krámos, B. (2013) · Biomolecules · doi:10.3390/biom3030662 · Cited by 29
Choi, E.-J., Kim, H.-I., Kim, J.-A., Jun, S. Y., Kang, S. H., Park, D., Son, S.-J., Kim, Y., & Shin, O. S. (2015) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-015-6382-y · Cited by 29
Baldwin, H. E., Blanco, D. M., McKeever, C., Paz, N., Vasquez, Y. N., Quiring, J. N., Enloe, C., León, E. D., & Stasko, N. (2016) · PubMed Central · Cited by 29
Plasmodium infection and oxidative status in breeding great tits, Parus major
Delhaye, J., Jenkins, T., & Christe, P. (2016) · Malaria Journal · doi:10.1186/s12936-016-1579-9 · Cited by 29
Immunostimulatory Effect of Enzyme-Modified Hizikia fusiformein a Mouse Model In Vitro and Ex Vivo
Park, S., Hwang, E., Shin, Y., Lee, D., Yang, J.-E., Park, J.-H., & Yi, T. (2017) · Marine Biotechnology · doi:10.1007/s10126-017-9727-y · Cited by 29
Ruhl, T., Kim, B., & Beier, J. P. (2018) · Experimental Cell Research · doi:10.1016/j.yexcr.2018.07.030 · Cited by 29
Dagah, O. M. A., Silaa, B. B., Zhu, M., Pan, Q., Qi, L., Liu, X., Liu, Y., Peng, W., Ullah, Z., Yudas, A. F., et al. (2024) · Antioxidants · doi:10.3390/antiox13050545 · Cited by 28
Macrophage NOS2 in Tumor Leukocytes
Brüne, B., Courtial, N., Dehne, N., Syed, S. N., & Weigert, A. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6811 · Cited by 28
Carey, R. M., Palmer, J. N., Adappa, N. D., & Lee, R. J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1096242 · Cited by 28
Kuroiwa, M., Yamaguchi, S.-I., Kato, Y., Hori, A., Toyoura, S., Nakahara, M., Morimoto, N., & NAKAYAMA, M. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.162586 · Cited by 29
Plasma medicine for neuroscience—an introduction
Yan, X., Ouyang, J., Zhang, C., Shi, Z., Wang, B., & Ostrikov, K. (2019) · Chinese Neurosurgical Journal · doi:10.1186/s41016-019-0172-9 · Cited by 28
Ghosh, A., Sumi, M. P., Tupta, B., Okamoto, T., Aulak, K. S., Tsutsui, M., Shimokawa, H., ERZURUM, S. C., & Stuehr, D. J. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102478 · Cited by 27
Somasundaram, V., Nadhan, R., Hemalatha, S. K., Sengodan, S. K., & Srinivas, P. (2016) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2016.03.004 · Cited by 27
Arginine, histidine and tryptophan: A new hope for cancer immunotherapy
Tantawy, A. A., & Naguib, D. M. (2019) · PharmaNutrition · doi:10.1016/j.phanu.2019.100149 · Cited by 27
Ruksiriwanich, W., Khantham, C., Linsaenkart, P., Chaitep, T., Rachtanapun, P., Jantanasakulwong, K., Phimolsiripol, Y., Jambrak, A. ., Nazir, Y., Yooin, W., et al. (2021) · International Journal of Food Science & Technology · doi:10.1111/ijfs.15338 · Cited by 27
Nitrosative stress and cytokines are linked with the severity of sepsis and organ dysfunction
Kumar, S., Gupta, E., Srivastava, V. K., Kaushik, S., Saxena, J., Goyal, L., Mehta, S. K., & Jyoti, A. (2018) · British Journal of Biomedical Science · doi:10.1080/09674845.2018.1543160 · Cited by 27
Roberts, J. M., Milo, S., & Metcalf, D. G. (2024) · Microorganisms · doi:10.3390/microorganisms12122543 · Cited by 27
Berka, V., Liu, W., Wu, G., & Tsai, A.-L. (2014) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2014.06.011 · Cited by 26
Salama, M. A. M., Mostafa, N. E., El-Aal, N. F. A., Moawad, H. S. F., Hammad, S. K., Adel, R., & Mostafa, E. (2021) · Journal of Parasitic Diseases · doi:10.1007/s12639-021-01412-y · Cited by 28
Metabolic Snapshot of Plasma Samples Reveals New Pathways Implicated in SARS-CoV-2 Pathogenesis
Albóniga, O. E., Jiménez, D., Sánchez‐Conde, M., Vizcarra, P., Ron, R., Herrera, S., Martínez‐Sanz, J., Moreno, E., Moreno, S., Barbas, C., et al. (2022) · Journal of Proteome Research · doi:10.1021/acs.jproteome.1c00786 · Cited by 26
Haddad, F., Soliman, A. M., Wong, M. E., Albers, E. H., Semple, S. L., Torrealba, D., Heimroth, R. D., Nashiry, A., Tierney, K. B., & Barreda, D. R. (2023) · eLife · doi:10.7554/elife.83644 · Cited by 26
Téllez‐Isaías, G., Eisenreich, W., Petrone-García, V. M., Hernández-Velasco, X., Castellanos-Huerta, C.-H., Téllez‐Isaías, G., Latorre, J. D., Bottje, W. G., Señas-Cuesta, R., Coles, M. E., et al. (2023) · German Journal of Veterinary Research · doi:10.51585/gjvr.2023.1.0051 · Cited by 28
Redox regulation of Janus kinase
Duhé, R. J. (2013) · JAK-STAT · doi:10.4161/jkst.26141 · Cited by 26
Yoshikawa, Y., Nasuno, R., Kawahara, N., Nishimura, A., Watanabe, D., & Takagi, H. (2016) · Nitric Oxide · doi:10.1016/j.niox.2016.04.003 · Cited by 26
Role of oxidant–antioxidant balance in reproduction of domestic animals
Talukder, S., Kerrisk, K. L., Gabai, G., & Celi, P. (2017) · Animal Production Science · doi:10.1071/an15619 · Cited by 26
Nanoamplifiers synthesized from gadolinium and gold nanocomposites for magnetic resonance imaging
Tian, X., Shao, Y., He, H., Liu, H., Shen, Y., Huang, W., & Li, L. (2013) · Nanoscale · doi:10.1039/c3nr00170a · Cited by 25
Nanotechnology Allied to Nitric Oxide Release Materials for Dermatological Applications
Seabra, A. B., & Durán, N. (2012) · Current Nanoscience · doi:10.2174/157341312801784159 · Cited by 25
Bayliak, M. M., Lylyk, M. P., Maniukh, O., Storey, J. M., Storey, K. B., & Lushchak, V. I. (2017) · Journal of Comparative Physiology B · doi:10.1007/s00360-017-1113-6 · Cited by 25
Batista, K. K. S., Vieira, C. S., Florentino, E. B., Caruso, K. F. B., Teixeira, P. T. P., Moraes, C. D. S., Genta, F. A., Azambuja, P., & de Castro, D. P. (2020) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2020.104100 · Cited by 25
Prajapati, N., Karan, A., Khezerlou, E., & DeCoster, M. A. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2020.629835 · Cited by 26
Avian immunosuppressive diseases and immune evasion
Schat, K. A., & Skinner, M. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-818708-1.00018-x · Cited by 25
Wang, Y., Shen, X., Yin, K., Miao, C., Sun, Y., Mao, S., Liu, D., & Sheng, J. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.02.037 · Cited by 25
Carey, R. M., Hariri, B. M., Adappa, N. D., Palmer, J. N., & Lee, R. J. (2022) · Cells · doi:10.3390/cells11091478 · Cited by 25
Mladineo, I., Volpatti, D., Beraldo, P., Rigos, G., Katharios, P., & Padrós, F. (2023) · Reviews in Aquaculture · doi:10.1111/raq.12839 · Cited by 25
Kearney, S. J., Delgado, C., & Lenz, L. L. (2012) · Immunologic Research · doi:10.1007/s12026-012-8362-y · Cited by 26
Hertz, R., Lulu, S. B., Shahi, P., Trebicz‐Geffen, M., Benhar, M., & Ankri, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091518 · Cited by 25
A poly(γ‐glutamic acid)‐based hydrogel loaded with superoxide dismutase for wound healing
Zhuang, H., Hong, Y., Gao, J., Chen, S., Ma, Y., & Wang, S. (2015) · Journal of Applied Polymer Science · doi:10.1002/app.42033 · Cited by 25
Nitric oxide release from a photoactive water-soluble ruthenium nitrosyl. Biological effects
Crisalli, M., Franco, L. P., Silva, B. R., Holanda, A. K. M., Bendhack, L. M., da Silva, R. S., & Ford, P. C. (2018) · Journal of Coordination Chemistry · doi:10.1080/00958972.2018.1469129 · Cited by 25
Nitric oxide radicals are emitted by wasp eggs to kill mold fungi
Strohm, E., Herzner, G., Rüther, J., Kaltenpoth, M., & Engl, T. (2019) · eLife · doi:10.7554/elife.43718 · Cited by 25
Cheng, R. Y. S., Basudhar, D., Ridnour, L. A., Heinecke, J. L., Kesarwala, A. H., Glynn, S. A., Switzer, C., Ambs, S., Miranda, K. M., & Wink, D. A. (2014) · Nitric Oxide · doi:10.1016/j.niox.2014.08.003 · Cited by 25
Self-citationMandujano-Tinoco, E. A., Sultan, E., Ottolenghi, A., Gershoni‐Yahalom, O., & Rosental, B. (2021) · Cells · doi:10.3390/cells10081853 · Cited by 25
Metadata
- Authors
- Wink, D. A., Hines, H. B., Cheng, R. Y. S., Switzer, C. H., Flores-Santana, W., Vitek, M. P., Ridnour, L. A., & Colton, C. A.
- Affiliations
- National Institutes of Health (US)
- United States Army Medical Research Institute of Infectious Diseases (US)
- Radiation Biology Branch, National Cancer Institute, National Institutes of Health , Bethesda, Maryland, USA
- Duke Medical Center (US)
- Corresponding author
- Wink, David A
- Colton, Carol A
- ORCID
- Venue
- Journal of Leukocyte Biology
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-01-13
- Volume
- 89
- Issue
- 6
- Pages
- 873-891
- ISSN
- 0741-5400 (ISSN-L)
- 1938-3673
- PMC
- PMC3100761
- OpenAlex
- W2171480404
- Cited by
- 765
- References
- 259
- Citations by year
- 2026: 25 · 2025: 58 · 2024: 46 · 2023: 57 · 2022: 69 · 2021: 74 · 2020: 56 · 2019: 44 · 2018: 40 · 2017: 60 · 2016: 53 · 2015: 57 · 2014: 48 · 2013: 35 · 2012: 27
- FWCI
- 3.58
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Leukocyte Biology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (R01AG031845, R01AG031124)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Keywords
- nitric oxide, reactive oxygen species, reactive nitrogen species, redox signaling, immune regulation, phagosome, immunosuppression, wound healing, Th1/Th2 balance, signal transduction, pathogen eradication
- MeSH terms
- Animals, Humans, Immunity, Cellular, Nitric Oxide, Oxidation-Reduction, Signal Transduction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
