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Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4
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ANGPTL4 overexpression increases triglycerides.
“and ANGPTL4 overexpression increases triglycerides (16, 22, 26).”
From Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8 (2021) · cites this paper as [22]
The N-terminal coiled-coil domain of ANGPTL4 mediates the formation of oligomers, mostly dimers and tetramers.
“The N-terminal coiled-coil domain of ANGPTL4 mediates the formation of oligomers, mostly dimers and tetramers (22, 89, 96).”
From Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8 (2021) · cites this paper as [22]
Oligomerization appears to be required for LPL inhibition.
“Oligomerization appears to be required for LPL inhibition (22, 89),”
From Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8 (2021) · cites this paper as [22]
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The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
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Köster, A., Chao, Y. B., Mosior, M., Ford, A., Gonzalez-DeWhitt, P. A., Hale, J. E., Li, D., Qiu, Y., Fraser, C. C., Yang, D. D., et al. (2005) · Endocrinology · doi:10.1210/en.2005-0476 · Cited by 427
Mandard, S., Zandbergen, F., van Straten, E., Wahli, W., Kuipers, F., Müller, M., & Kersten, S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m506519200 · Cited by 433
The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism
Hato, T., Tabata, M., & Oike, Y. (2008) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2007.10.003 · Cited by 351
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Wu, S. A., Kersten, S., & Qi, L. (2021) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2020.11.005 · Cited by 225
DUVAL, C., MULLER, M., & KERSTEN, S. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2007.05.003 · Cited by 199
Staiger, H., Haas, C., Machann, J., Werner, R., Weisser, M., Schick, F., Machicao, F., Stefan, N., Fritsche, A., & Häring, H.-U. (2009) · Diabetes · doi:10.2337/db07-1438 · Cited by 183
Oligomerization and Multimerization Are Critical for Angiopoietin-1 to Bind and Phosphorylate Tie2
Kim, K.-T., Choi, H.-H., Steinmetz, M. O., Maco, B., Kammerer, R. A., Ahn, S. Y., Kim, H.-Z., Lee, G. M., & Koh, G. Y. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500292200 · Cited by 170
Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8
Sylvers-Davie, K. L., & Davies, B. S. J. (2021) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00195.2021 · Cited by 154
Angiopoietin-like Protein 4 Inhibition of Lipoprotein Lipase
Lafferty, M. J., Bradford, K. C., Erie, D. A., & Neher, S. B. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.497602 · Cited by 88
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Olshan, D. S., & Rader, D. J. (2018) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2018.01.012 · Cited by 30
ANGPTL4 binds to the leptin receptor to regulate ectopic bone formation
Hu, H., Luo, S., Lai, P., Lai, M., Mao, L., Zhang, S., Jiang, Y., Wen, J., Zhou, W., Liu, X., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2310685120 · Cited by 18
Metadata
- Authors
- Ge, H., Yang, G., Yu, X., Pourbahrami, T., & Li, C.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 2004-11
- Volume
- 45
- Issue
- 11
- Pages
- 2071-2079
- ISSN
- 0022-2275
- Cited by
- 104
- References
- 2
- Language
- en
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