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Stratum Corneum Function: A Structural Study with Dynamic Synchrotron X-ray Diffraction Experiments

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Biomimetic Stratum Corneum Liposome Models: Lamellar Organization and Permeability Studies

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Role of Nutritional Elements in Skin Homeostasis: A Review

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Skin lipid profiling in normal and seborrhoeic shih tzu dogs

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Controlled Penetration of a Novel Dimeric Ceramide into and across the Stratum Corneum Using Microemulsions and Various Types of Semisolid Formulations

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Practical syntheses of D-erythro and L-threo-ceramide [NDS] and difference in contribution of each isomer in microstructure of stratum corneum intercellular lipids

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Role of Ceramides in Drug Delivery

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The application of label-free imaging technologies in transdermal research for deeper mechanism revealing

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Chiral 4- O -acylterpineol as transdermal permeation enhancers: insights of the enhancement mechanisms of a transdermal enantioselective delivery system for flurbiprofen

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Lycoperoside H, a Tomato Seed Saponin, Improves Epidermal Dehydration by Increasing Ceramide in the Stratum Corneum and Steroidal Anti-Inflammatory Effect

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Efficacy of Topical Application of a Skin Moisturizer Containing Pseudo-Ceramide and a Eucalyptus Leaf Extract on Atopic Dermatitis: A Review

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Short periodicity phase based on ceramide [AP] in the model lipid membranes of stratum corneum does not change during hydration

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Dietary intake of glucono-δ-lactone attenuates skin inflammation and contributes to maintaining skin condition

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Resolving Issues About Efficacy and Safety of Low-Dose Codeine in Combination Analgesic Drugs: A Systematic Review

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Properties of Skin in Chinese Infants: Developmental Changes in Ceramides and in Protein Secondary Structure of the Stratum Corneum

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Tape stripping method is useful for the quantification of antimicrobial peptides on the human skin surface including the stratum corneum

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Current Insights on Lipidomics in Dermatology: A Systematic Review

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Electrospray ionization with higher-energy collision dissociation tandem mass spectrometry toward characterization of ceramides as [M + Li]+ ions: Mechanisms of fragmentation and structural identification

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RNA sequencing and lipidomics uncovers novel pathomechanisms in recessive X-linked ichthyosis

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Ceramides as Possible Nutraceutical Compounds: Characterization of the Ceramides of the Moro Blood Orange (Citrus sinensis)

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Lipidomic platform for structural identification of skin ceramides with α-hydroxyacyl chains

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Considering Phytosphingosine-Based Ceramide Formulations for Atopic Skin Care

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Enrichment of Short-Chain Ceramides and Free Fatty Acids in the Skin Epidermis, Liver, and Kidneys of db/db Mice, a Type 2 Diabetes Mellitus Model

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Characterization of Ceramides with Phytosphingosine Backbone by Hydrogen-deuterium Exchange Mass Spectrometry

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Effects of a moisturizer containing pseudo‐ceramide and a eucalyptus extract on sweating function in adult atopic dermatitis: a double‐blind, randomized, controlled left‐right comparison clinical trial

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Human as the Ultimate Wound Healing Model: Strategies for Studies Investigating the Dermal Lipidome

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Canine epidermal lipid sampling by skin scrub revealed variations between different body sites and normal and atopic dogs

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Epidermal Barrier in Atopic Dermatitis

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Function of ceramides in the skin and its relationship with skin disease

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The Influence of the Acyl Chain on the Transdermal Penetration-Enhancing Effect of Synthetic Phytoceramides

Veryser, L., Boonen, J., Taevernier, L., Guillaume, J., Risseeuw, M., Shah, S. N. H., Roche, N. A., Calenbergh, S. V., & Spiegeleer, B. M. J. D. (2014) · Skin Pharmacology and Physiology · doi:10.1159/000365730 · Cited by 10

Transcriptional profiling of epidermal barrier formation in vitro

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Ethnic differences in stratum corneum functions between Chinese and Thai infants residing in Bangkok, Thailand

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Ceramides from Sea Red Rice Bran Improve Health Indicators and Increase Stress Resistance of Caenorhabditis elegans through Insulin/IGF-1 Signaling (IIS) Pathway and JNK-1

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Palmitoylation enhances short polar peptide permeation across stratum corneum lipid bilayer: A molecular dynamics study

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Skin inflammation and impaired adipogenesis in a mouse model of acid ceramidase deficiency

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Mass Spectrometry for Determination of Bioactive Compounds

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Exploring the potentials of nurture: 2nd and 3rd generation explant human skin equivalents

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The role of skin barrier function in atopic dermatitis: an update

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Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak1

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Comparison of ceramide retention in the stratum corneum between dry skin and normal skin using animal model with fluorescent imaging method

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Association of dry skin with intercellular lipid composition of stratum corneum after erlotinib administration

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Influence of Variation in Eumelanin Content on Absorbance Spectra of Liquid Skin‐like Phantoms

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Comparison of three different sampling methods for canine skin lipids

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Fatty Acid Chain Length Dependence of Phase Separation Kinetics in Stratum Corneum Models by IR Spectroscopy

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Nonhydroxylated 1-O-acylceramides in vernix caseosa

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Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid

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Comparison between ammonium formate and ammonium fluoride in the analysis of stratum corneum lipids by reversed phase chromatography coupled with high resolution mass spectrometry

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High‐energy collision‐induced dissociation of [M+Na]+ ions desorbed by fast atom bombardment of ceramides isolated from the starfish Distolasterias nipon

Yoo, J., Park, T., Bang, G., Lee, C., Rho, J., & Kim, Y. H. (2013) · Journal of Mass Spectrometry · doi:10.1002/jms.3140 · Cited by 7

The Art and Practice of Lipidomics

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Horse-Derived Ceramide Accentuates Glucosylceramide Synthase and Ceramide Synthase 3 by Activating PPARβ/δ and/or PPARγ to Stimulate Ceramide Synthesis

Igarashi, T., Yanagi, H., Yagi, M., Ichihashi, M., & Imokawa, G. (2023) · Biomedicines · doi:10.3390/biomedicines11020548 · Cited by 6

Lipid Biomimetic Models as Simple Yet Complex Tools to Predict Skin Permeation and Drug–Membrane Biophysical Interactions

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Effect of low humidity on the barrier functions of keratinocytes in a reconstructed human epidermal model

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Non-invasive Microneedle Application Increases Ceramide and Natural Moisturizing Factors in a Reconstructed Human Skin Model

Sakuraba, K., Kojima, Y., Terahara, T., Kuma, H., & Tokudome, Y. (2023) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b23-00294 · Cited by 6

Sphingosine-1-phosphate as signaling molecule in the skin

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Effects of age, sex, and breed on the composition of free extractable ceramides in the stratum corneum of healthy dogs

Yoon, J., Sasaki, A., Shimada, K., Ide, K., Iwasaki, T., & Nishifuji, K. (2021) · Veterinary Research Communications · doi:10.1007/s11259-021-09835-x · Cited by 6

Phase Separation in Lipid Lamellae Result from Ceramide Conformations and Lateral Packing Structure

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Effect of Molecular Assembly for Emulsion and Gel Formulations

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Ceramide NPs derived from natural oils of Korean traditional plants enhance skin barrier functions and stimulate expressions of genes for epidermal homeostasis

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Application of sphingolipid-based nanocarriers in drug delivery: an overview

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Study of the potential of stratum corneum lipids and exogenous molecules interaction by fluorescence spectroscopy for the estimation of percutaneous penetration

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Two- and Three-Dimensional Physical–Chemical Characterization of CER[AP]: A Study of Stereochemistry and Chain Symmetry

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Stratum corneum ceramide profiles in vitro, ex vivo, and in vivo: characterization of the α-hydroxy double esterified ceramides

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Squalene Chemistry and Biology

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Oleogels Produced by Direct Methods Using as Gelator: Fatty Acids (Including 12-HSA), Fatty Alcohols, Ceramides, Lecithins, Sterols, Cellulose Fibers, and Fumed Silica

Li, L., Liu, G., & Guo, Z. (2024) · Springer eBooks · doi:10.1007/978-3-031-46831-5_8 · Cited by 4

Topical Peroxisome Proliferator-Activated Receptor Agonist Induces Molecular Alterations Enhancing Barrier Function and Water-Holding Capacity of the Human Stratum Corneum In Vivo

Darvin, M. E., Salazar, A., Schleusener, J., Lademann, J. M., & von Hagen, J. (2024) · Cosmetics · doi:10.3390/cosmetics11020044 · Cited by 4

Ionic composition of Shotokuseki extract alters cell differentiation and lipid metabolism in three-dimensional cultured human epidermis

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Molecular Organization of the Lipid Matrix in Stratum Corneum and Its Relevance for the Protective Functions of Human Skin

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Synthesis of novel ceramide-like penetration enhancers

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The Importance of Stratum Corneum Lipid Organization for Proper Barrier Function

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Season‐ and facial site‐specific skin changes due to long‐term mask wearing during the COVID‐19 pandemic

Nakamura, T., Yoshida, H., Haneoka, M., Nakamura, S., & Takahashi, Y. (2022) · Skin Research and Technology · doi:10.1111/srt.13196 · Cited by 3

Efficient lipase-catalyzed synthesis of ceramide III series compounds in an eco-friendly solvent

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Skin xerosis: symptom, syndrome or disease? (in Russian only)

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Lipid composition of the stratum corneum in different regions of the body of Kuhl's pipistrelle from the Negev Desert, Israel

Cockley, A., Champagne, A. M., Ben‐Hamo, M., Pinshow, B., Korine, C., & Muñoz‐Garcia, A. (2021) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2021.111074 · Cited by 3

Identification of Phytosphingosine-Based 1-O-Acylceramide in Human Stratum Corneum and Investigation of Its Role in Skin Barrier

Kang, B.-G., Choi, H. K., Liu, K., Hong, S. K., Kim, J. W., Lee, E. O., & Park, C. S. (2025) · Cosmetics · doi:10.3390/cosmetics12020047 · Cited by 2

Microfluidic preparation of ceramide E liposomes and properties

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Skin Lipids

Uchida, Y. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802005-0.00041-0 · Cited by 2

Multi‐omics analysis to evaluate the effects of solar exposure and a broad‐spectrum SPF50+ sunscreen on markers of skin barrier function in a skin ecosystem model

Jacques, C., Jamin, E. L., Noustens, A., Lauze, C., Jouanin, I., Doat, G., Debrauwer, L., Bessou‐Touya, S., Stockfleth, E., & Duplan, H. (2024) · Photochemistry and Photobiology · doi:10.1111/php.14001 · Cited by 2

Synchrotron-Based X-ray Methods as Powerful Tools for the Characterization of Monolayers at the Air/Liquid Interface

Vollhardt, D., & Brezesinski, G. (2015) · ACS symposium series · doi:10.1021/bk-2015-1215.ch018 · Cited by 2

Effect of galactosylceramide on stratum corneum intercellular lipid synthesis in a three-dimensional cultured human epidermis model

Kage, M., Itaya, Y., Horikoshi, J., & Tokudome, Y. (2021) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2021.101135 · Cited by 3

Role of Sphingolipids in Non-melanoma Skin Cancer

Lin, C., & Mao, C. (2015) · Springer eBooks · doi:10.1007/978-3-319-20750-6_5 · Cited by 2

Development of an in vitro submerged culture system to synthesize epidermal ceramides in canine keratinocytes

Yoon, J., Nishifuji, K., & Iwasaki, T. (2020) · Research in Veterinary Science · doi:10.1016/j.rvsc.2020.02.011 · Cited by 2

Removal of soman from injured skin by haemostatic materials

Dalton, C. H. (2013) · University of Birmingham Institutional Research Archive (University of Birmingham) · Cited by 2

Bio-Functional Natural Products in Edible Resources for Human Health and Beauty

Morikawa, T. (2022) · MDPI eBooks · doi:10.3390/books978-3-0365-5071-8

Research Advancements in the Immunomodulating Effect of Sphingosine-1-Phosphate in Skin Diseases

Ding, M.-L., Li, H., Xu, J.-J., Ren, K., & Zhang, W. (2024) · International Journal of Dermatology and Venereology · doi:10.1097/jd9.0000000000000370 · Cited by 1

Lipidomic Insights into Seborrheic Dermatitis: Clinical Evaluation of Sebum Changes Using SpiderMass

Darras, L., Ipinazar, C., Gravier, E., Mercadié, A., Villaret, A., Marinescu, R., Maitre, M., Géniès, C., Mengeaud, V., Fournier, I., et al. (2026) · Dermatology and Therapy · doi:10.1007/s13555-026-01719-9 · Cited by 1

Atopic Dermatitis (AD) and Lipids

Masukawa, Y. (2014) · Springer eBooks · doi:10.1007/978-3-319-09943-9_24 · Cited by 1

Importância da barreira epidérmica na dermatite atópica canina: Revisão

Villalobos, W. R., & Beltrán, L. R. (2016) · PubVet · doi:10.22256/pubvet.v10n7.560-567 · Cited by 2

Pflanzliche Ceramide zur kosmetischen Anwendung

Tessema, E. N., Neubert, R. H. H., & Wohlrab, J. (2019) · Aktuelle Dermatologie · doi:10.1055/a-0881-6924 · Cited by 1

Development and Properties of the Optically Active Ceramides

Ishida, K. (2014) · Hyomen Kagaku · doi:10.1380/jsssj.35.23 · Cited by 1

Review Ceramide’ Role in Skin

Uchida, Y. (2018) · Drug Delivery System · doi:10.2745/dds.33.252 · Cited by 1

The role of epidermal lipids in the pathogenesis of psoriasis

Khlebnikova, A. N. (2020) · Russian Journal of Clinical Dermatology and Venereology · doi:10.17116/klinderma202019021231 · Cited by 1

The effects of obesity on the human body, part I: Skin and musculoskeletal

Dupont, G. C., Bordes, S. J., Lachkar, S., Wahl, L., Iwanaga, J., Loukas, M., & Tubbs, R. S. (2020) · Clinical Anatomy · doi:10.1002/ca.23683 · Cited by 1

Comprehensive Mouse Skin Ceramide Analysis on a Solid-Phase and TLC Separation with High-Resolution Mass Spectrometry Platform

Lin, M., Miner, J. H., & Hsu, F. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1410-5_10 · Cited by 1

Corneocyte Analysis

Hirao, T. (2016) · Springer eBooks · doi:10.1007/978-3-662-47398-6_68 · Cited by 1

Corneocyte Analysis

Hirao, T. (2015) · Springer eBooks · doi:10.1007/978-3-642-27814-3_68-2 · Cited by 1

Reversed-Phase Liquid Chromatography Mass Spectrometry (RP-LC-MS) in Lipidomics

t’Kindt, R., Sandra, P. J. F., & Sandra, K. (2016) · Springer eBooks · doi:10.1007/978-94-007-7864-1_61-1 · Cited by 2

Comprehensive quantification of ceramide species in human stratum corneum

Masukawa, Y., Narita, H., Sato, H., Naoe, A., Kondo, N., Sugai, Y., Oba, T., Homma, R., Ishikawa, J., Takagi, Y., et al. (2009) · Journal of Lipid Research · doi:10.1194/jlr.d800055-jlr200 · Cited by 228

Profiling and Characterizing Skin Ceramides Using Reversed-Phase Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry

t’Kindt, R., Jorge, L., Dumont, E., Couturon, P., David, F., Sandra, P., & Sandra, K. (2012) · Analytical Chemistry · doi:10.1021/ac202646v · Cited by 202

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery

van Smeden, J., Hoppel, L., van der Heijden, R., Hankemeier, T., Vreeken, R. J., & Bouwstra, J. A. (2011) · Journal of Lipid Research · doi:10.1194/jlr.m014456 · Cited by 229

A lipidomic platform establishment for structural identification of skin ceramides with non-hydroxyacyl chains

Shin, J.-H., Shon, J. C., Lee, K., Kim, S., Park, C. S., Choi, E. H., Lee, C. H., Lee, H. S., & Liu, K. (2014) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-013-7601-y · Cited by 28

Investigation of the Molecular Structure of the Human Stratum Corneum Ceramides [NP] and [EOS] by Mass Spectrometry

Hinder, A., Schmelzer, C. E. H., Rawlings, A. V., & Neubert, R. H. H. (2011) · Skin Pharmacology and Physiology · doi:10.1159/000322303 · Cited by 36