Cited by 171Dementia and Cognitive Impairment ResearchNeurobiology of Language and BilingualismAmyotrophic Lateral Sclerosis Research

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Differentiating primary progressive aphasias in a brief sample of connected speech

Open access

Ash, Sharon, Evans, Emily, O'Shea, Jessica, Powers, John, Boller, Ashley, Weinberg, Danielle, Haley, Jenna, McMillan, Corey, Irwin, David J., Rascovsky, Katya, Grossman, Murray·2013·Neurology

DOI 10.1212/wnl.0b013e31829c5d0ePMC PMC3772830

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVE: A brief speech expression protocol that can be administered and scored without special training would aid in the differential diagnosis of the 3 principal forms of primary progressive aphasia (PPA): nonfluent/agrammatic PPA, logopenic variant PPA, and semantic variant PPA. METHODS: We used a picture-description task to elicit a short speech sample, and we evaluated impairments in speech-sound production, speech rate, lexical retrieval, and grammaticality. We compared the results with those obtained by a longer, previously validated protocol and further validated performance with multimodal imaging to assess the neuroanatomical basis of the deficits. RESULTS: We found different patterns of impaired grammar in each PPA variant, and additional language production features were impaired in each: nonfluent/agrammatic PPA was characterized by speech-sound errors; logopenic variant PPA by dysfluencies (false starts and hesitations); and semantic variant PPA by poor retrieval of nouns. Strong correlations were found between this brief speech sample and a lengthier narrative speech sample. A composite measure of grammaticality and other measures of speech production were correlated with distinct regions of gray matter atrophy and reduced white matter fractional anisotropy in each PPA variant. CONCLUSIONS: These findings provide evidence that large-scale networks are required for fluent, grammatical expression; that these networks can be selectively disrupted in PPA syndromes; and that quantitative analysis of a brief speech sample can reveal the corresponding distinct speech characteristics.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1212/wnl.0b013e31829c5d0e

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Symmetric diffeomorphic image registration with cross-correlation: Evaluating automated labeling of elderly and neurodegenerative brain
Avants, B., Epstein, C. L., Grossman, M., & Gee, J. C. (2007) · Medical Image Analysis · doi:10.1016/j.media.2007.06.004 · Cited by 5,924
Self-citation
The cortical organization of speech processing
Hickok, G., & Poeppel, D. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2113 · Cited by 5,495
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., van Swieten, J. C., Seelaar, H., Dopper, E. G. P., Onyike, C. U., et al. (2011) · Brain · doi:10.1093/brain/awr179 · Cited by 5,221
Self-citation
Classification of primary progressive aphasia and its variants
Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. F., Ogar, J. M., Rohrer, J. D., Black, S., Boeve, B. F., et al. (2011) · Neurology · doi:10.1212/wnl.0b013e31821103e6 · Cited by 5,141
Self-citation
The assessment of aphasia and related disorders
Goodglass, H., & Kaplan, E. (1972) · Medical Entomology and Zoology · Cited by 3,258
Assessment of Aphasia and Related Disorders
Sarno, M. T. (1973) · Physical Therapy · doi:10.1093/ptj/53.2.225b · Cited by 2,256
The brain basis of language processing: from structure to function.
Friederici, A. D. (2011) · Physiological Reviews · doi:10.1152/physrev.00006.2011 · Cited by 2,140
Cognition and anatomy in three variants of primary progressive aphasia
Gorno‐Tempini, M. L., Dronkers, N. F., Rankin, K. P., Ogar, J. M., Phengrasamy, L., Rosen, H. J., Johnson, J. K., Weiner, M. W., & Miller, B. L. (2004) · Annals of Neurology · doi:10.1002/ana.10825 · Cited by 1,657
Clinical and Pathological Diagnosis of Frontotemporal Dementia
McKhann, G. M. (2001) · Archives of Neurology · doi:10.1001/archneur.58.11.1803 · Cited by 1,478
A new brain region for coordinating speech articulation
Dronkers, N. F. (1996) · Nature · doi:10.1038/384159a0 · Cited by 1,192

Show all 38 references

Sorted by citations

Connected Speech in Neurodegenerative Language Disorders: A Review
Boschi, V., Catricalà, E., Consonni, M., Chesi, C., Moro, A., & Cappa, S. F. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.00269 · Cited by 362
Clinical, Anatomical, and Pathological Features in the Three Variants of Primary Progressive Aphasia: A Review
Montembeault, M., Brambati, S. M., Gorno‐Tempini, M. L., & Migliaccio, R. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00692 · Cited by 189
Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia
Giannini, L. A. A., Irwin, D. J., McMillan, C. T., Ash, S., Rascovsky, K., Wolk, D. A., Van Deerlin, V. M., Lee, E. B., Trojanowski, J. Q., & Grossman, M. (2017) · Neurology · doi:10.1212/wnl.0000000000004034 · Cited by 144
Self-citation
SAND: a Screening for Aphasia in NeuroDegeneration. Development and normative data
Catricalà, E., Gobbi, E., Battista, P., Miozzo, A., Polito, C., Boschi, V., Esposito, V., Cuoco, S., Barone, P., Sorbi, S., et al. (2017) · Neurological Sciences · doi:10.1007/s10072-017-3001-y · Cited by 113
Speech and language markers of neurodegeneration: a call for global equity
García, A. M., de Leon, J., Tee, B. L., Blasi, D. E., & Gorno-Tempini, M. L. (2023) · Brain · doi:10.1093/brain/awad253 · Cited by 102
Neuropsychological Profiles Differ among the Three Variants of Primary Progressive Aphasia
Butts, A. M., Machulda, M. M., Duffy, J. R., Strand, E. A., Whitwell, J. L., & Josephs, K. A. (2015) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617715000399 · Cited by 107
Frontotemporal Lobar Degeneration: A Clinical Approach
Karageorgiou, E., & Miller, B. L. (2014) · Seminars in Neurology · doi:10.1055/s-0034-1381735 · Cited by 107
Stealing Cookies in the Twenty-First Century: Measures of Spoken Narrative in Healthy Versus Speakers With Aphasia
Berube, S. K., Nonnemacher, J., Demsky, C., Glenn, S., Saxena, S., Wright, A. E., Tippett, D. C., & Hillis, A. E. (2018) · American Journal of Speech-Language Pathology · doi:10.1044/2018_ajslp-17-0131 · Cited by 91
Correlating natural language processing and automated speech analysis with clinician assessment to quantify speech-language changes in mild cognitive impairment and Alzheimer’s dementia
Yeung, A., Iaboni, A., Rochon, E. A., Lavoie, M., Santiago, C., Yancheva, M., Novikova, J., Xu, M., Robin, J., Kaufman, L. D., et al. (2021) · Alzheimer s Research & Therapy · doi:10.1186/s13195-021-00848-x · Cited by 90
Motor Speech Phenotypes of Frontotemporal Dementia, Primary Progressive Aphasia, and Progressive Apraxia of Speech
Poole, M. L., Brodtmann, A., Darby, D., & Vogel, A. P. (2017) · Journal of Speech, Language, and Hearing Research · doi:10.1044/2016_jslhr-s-16-0140 · Cited by 84
Speech and language impairments in behavioral variant frontotemporal dementia: A systematic review
Geraudie, A., Battista, P., García, A. M., Allen, I. E., Miller, Z. A., Gorno-Tempini, M. L., & Montembeault, M. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.10.015 · Cited by 80
Validated automatic speech biomarkers in primary progressive aphasia
Nevler, N., Ash, S., Irwin, D. J., Liberman, M., & Grossman, M. (2019) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.653 · Cited by 74
Self-citation
Data-driven classification of patients with primary progressive aphasia
Hoffman, P., Sajjadi, S. A., Patterson, K. E., & Nestor, P. J. (2017) · Brain and Language · doi:10.1016/j.bandl.2017.08.001 · Cited by 72
Classification of the primary progressive aphasias: principles and review of progress since 2011
Vandenberghe, R. R. (2016) · Alzheimer s Research & Therapy · doi:10.1186/s13195-016-0185-y · Cited by 77
Tau PET imaging predicts cognition in atypical variants of Alzheimer's disease
Phillips, J. S., Das, S. R., McMillan, C. T., Irwin, D. J., Roll, E. E., Da Re, F., Nasrallah, I. M., Wolk, D. A., & Grossman, M. (2018) · Human Brain Mapping · doi:10.1002/hbm.23874 · Cited by 68
Self-citation
What do pauses in narrative production reveal about the nature of word retrieval deficits in PPA?
Mack, J. E., Chandler, S. D., Meltzer‐Asscher, A., Rogalski, E. J., Weıntraub, S., Mesulam, M. M., & Thompson, C. K. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.08.019 · Cited by 72
Longitudinal decline in speech production in Parkinson's disease spectrum disorders
Ash, S., Jester, C., York, C., Kofman, O., Langey, R., Halpin, A., Firn, K., Perez, S. D., Chahine, L. M., Spindler, M., et al. (2017) · Brain and Language · doi:10.1016/j.bandl.2017.05.001 · Cited by 63
Self-citation
Automatic measurement of prosody in behavioral variant FTD
Nevler, N., Ash, S., Jester, C., Irwin, D. J., Liberman, M., & Grossman, M. (2017) · Neurology · doi:10.1212/wnl.0000000000004236 · Cited by 61
Self-citation
Distinctive pathological mechanisms involved in primary progressive aphasias
Leyton, C. E., Britton, A. K., Hodges, J. R., Halliday, G. M., & Kril, J. J. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2015.10.017 · Cited by 63
A ‘Mini Linguistic State Examination’ to classify primary progressive aphasia
Patel, N., Peterson, K. A., Ingram, R. U., Storey, I., Cappa, S. F., Catricalà, E., Halai, A. D., Patterson, K. E., Ralph, M. A. L., Rowe, J. B., et al. (2021) · Brain Communications · doi:10.1093/braincomms/fcab299 · Cited by 56
Characterization of the logopenic variant of primary progressive aphasia: A systematic review and meta-analysis
Conca, F., Esposito, V., Giusto, G., Cappa, S. F., & Catricalà, E. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101760 · Cited by 54
Primary Progressive Aphasia and Stroke Aphasia
Grossman, M., & Irwin, D. J. (2018) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000618 · Cited by 55
Self-citation
Motor speech signature of behavioral variant frontotemporal dementia: Refining the phenotype
Vogel, A. P., Poole, M. L., Pemberton, H., Caverlé, M. W. J., Boonstra, F. M. C., Low, E., Darby, D., & Brodtmann, A. (2017) · Neurology · doi:10.1212/wnl.0000000000004248 · Cited by 49
Lexical and Acoustic Speech Features Relating to Alzheimer Disease Pathology
Cho, S., Cousins, K. A. Q., Shellikeri, S., Ash, S., Irwin, D. J., Liberman, M. Y., Grossman, M., & Nevler, N. (2022) · Neurology · doi:10.1212/wnl.0000000000200581 · Cited by 51
Self-citation
Towards a Clearer Definition of Logopenic Progressive Aphasia
Leyton, C. E., & Hodges, J. R. (2013) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-013-0396-6 · Cited by 51
Quantification of motor speech impairment and its anatomic basis in primary progressive aphasia
Cordella, C., Quimby, M., Touroutoglou, A., Brickhouse, M., Dickerson, B. C., & Green, J. R. (2019) · Neurology · doi:10.1212/wnl.0000000000007367 · Cited by 49
A longitudinal study of speech production in primary progressive aphasia and behavioral variant frontotemporal dementia
Ash, S., Nevler, N., Phillips, J., Irwin, D. J., McMillan, C. T., Rascovsky, K., & Grossman, M. (2019) · Brain and Language · doi:10.1016/j.bandl.2019.04.006 · Cited by 47
Self-citation
A syntax–lexicon trade-off in language production
Rezaii, N., Mahowald, K., Ryskin, R. A., Dickerson, B. C., & Gibson, E. A. F. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2120203119 · Cited by 41
Narrative discourse deficits in amyotrophic lateral sclerosis
Ash, S., Menaged, A., Olm, C. A., McMillan, C. T., Boller, A., Irwin, D. J., McCluskey, L. F., Elman, L. B., & Grossman, M. (2014) · Neurology · doi:10.1212/wnl.0000000000000670 · Cited by 57
Self-citation
Personalized Repetitive Transcranial Magnetic Stimulation for Primary Progressive Aphasia
Pytel, V., Cabrera‐Martín, M. N., Delgado‐Álvarez, A., Ayala, J. L., Balugo, P., Delgado‐Alonso, C., Yus, M., Carreras, M. T., Carreras, J. L., Matías‐Guiu, J., et al. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210566 · Cited by 48
Linguistic Aspects of Primary Progressive Aphasia
Grossman, M. (2017) · Annual Review of Linguistics · doi:10.1146/annurev-linguistics-011516-034253 · Cited by 46
Self-citation
Automated profiling of spontaneous speech in primary progressive aphasia and behavioral-variant frontotemporal dementia: An approach based on usage-frequency
Zimmerer, V. C., Hardy, C. J. D., Eastman, J., Dutta, S., Varnet, L., Bond, R. L., Russell, L. L., Rohrer, J. D., Warren, J. D., & Varley, R. A. (2020) · Cortex · doi:10.1016/j.cortex.2020.08.027 · Cited by 39
A finer-grained linguistic profile of Alzheimer's disease and Mild Cognitive Impairment
Chapin, K., Clarke, N., Garrard, P., & Hinzen, W. (2022) · Journal of Neurolinguistics · doi:10.1016/j.jneuroling.2022.101069 · Cited by 51
Automated analysis of lexical features in frontotemporal degeneration
Cho, S., Nevler, N., Ash, S., Shellikeri, S., Irwin, D. J., Massimo, L., Rascovsky, K., Olm, C., Grossman, M., & Liberman, M. (2021) · Cortex · doi:10.1016/j.cortex.2021.01.012 · Cited by 41
Self-citation
Long-Term maintenance of anomia treatment effects in primary progressive aphasia
Meyer, A. M., Tippett, D. C., Turner, R. S., & Friedman, R. B. (2018) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2018.1425146 · Cited by 43
Identification of the main components of spontaneous speech in primary progressive aphasia and their neural underpinnings using multimodal MRI and FDG-PET imaging
Matías‐Guiu, J. A., Suárez‐Coalla, P., Yus, M., Pytel, V., Hernández‐Lorenzo, L., Delgado‐Alonso, C., Delgado‐Álvarez, A., Gómez‐Ruiz, N., Polidura, C., Cabrera‐Martín, M. N., et al. (2021) · Cortex · doi:10.1016/j.cortex.2021.10.010 · Cited by 39
Why study connected speech production?
Ash, S., & Grossman, M. (2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781107323667.003 · Cited by 38
Self-citation
Primary progressive aphasia: a review of neuropsychological tests for the assessment of speech and language disorders
Battista, P., Miozzo, A., Piccininni, M., Catricalà, E., Capozzo, R., Tortelli, R., Padovani, A., Cappa, S. F., & Logroscino, G. (2017) · Aphasiology · doi:10.1080/02687038.2017.1378799 · Cited by 40
Automated analysis of natural speech in amyotrophic lateral sclerosis spectrum disorders
Nevler, N., Ash, S., McMillan, C. T., Elman, L. B., McCluskey, L. F., Irwin, D. J., Cho, S., Liberman, M., & Grossman, M. (2020) · Neurology · doi:10.1212/wnl.0000000000010366 · Cited by 36
Self-citation
Using narratives in differential diagnosis of neurodegenerative syndromes
Faroqi-Shah, Y., Treanor, A., Ratner, N. B., Ficek, B., Webster, K., & Tsapkini, K. (2020) · Journal of Communication Disorders · doi:10.1016/j.jcomdis.2020.105994 · Cited by 32
Evaluation of Linguistic Markers of Word-Finding Difficulty and Cognition in Parkinson's Disease
Smith, K. M., Ash, S., Xie, S. X., & Grossman, M. (2018) · Journal of Speech Language and Hearing Research · doi:10.1044/2018_jslhr-l-17-0304 · Cited by 34
Self-citation
Moving Toward Non-transcription based Discourse Analysis in Stable and Progressive Aphasia
Dalton, S. G., Hubbard, H. I., & Richardson, J. D. (2019) · Seminars in Speech and Language · doi:10.1055/s-0039-3400990 · Cited by 32
Breaking the flow of thought: Increase of empty pauses in the connected speech of people with mild and moderate Alzheimer's disease
Lofgren, M., & Hinzen, W. (2022) · Journal of Communication Disorders · doi:10.1016/j.jcomdis.2022.106214 · Cited by 32
The Mental Status Examination in Patients With Suspected Dementia
Grossman, M., & Irwin, D. J. (2016) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000298 · Cited by 32
Self-citation
Toolkit to Examine Lifelike Language (TELL): An app to capture speech and language markers of neurodegeneration
García, A. M., Johann, F., Echegoyen, R. E., Calcaterra, C., Riera, P., Belloli, L. M. L., & Carrillo, F. (2023) · Behavior Research Methods · doi:10.3758/s13428-023-02240-z · Cited by 29
Writing in Richardson variant of progressive supranuclear palsy in comparison to progressive non-fluent aphasia
Sitek, E. J., Barczak, A. K., Kluj-Kozłowska, K., Kozłowski, M., Narożańska, E., Konkel, A., Dąbrowska, M., Barcikowska, M., & Sławek, J. W. (2015) · Neurologia i Neurochirurgia Polska · doi:10.1016/j.pjnns.2015.05.004 · Cited by 29
Describing Phonological Paraphasias in Three Variants of Primary Progressive Aphasia
Dalton, S. G., Shultz, C., Henry, M. L., Hillis, A. E., & Richardson, J. D. (2018) · American Journal of Speech-Language Pathology · doi:10.1044/2017_ajslp-16-0210 · Cited by 29
Dissociation of quantifiers and object nouns in speech in focal neurodegenerative disease
Ash, S., Ternes, K., Bisbing, T. A., Min, N. E., Moran, E. E., York, C., McMillan, C. T., Irwin, D. J., & Grossman, M. (2016) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2016.06.013 · Cited by 25
Self-citation
Differences in Connected Speech Outcomes Across Elicitation Methods
Schnur, T. T., & Wang, S. (2023) · Aphasiology · doi:10.1080/02687038.2023.2239509 · Cited by 25
Word retrieval across the biomarker-confirmed Alzheimer's disease syndromic spectrum
Putcha, D., Dickerson, B. C., Brickhouse, M. J., Johnson, K. A., Sperling, R. A., & Papp, K. V. (2020) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2020.107391 · Cited by 25
Breakdowns in Informativeness of Naturalistic Speech Production in Primary Progressive Aphasia
Gallée, J., Cordella, C., Fedorenko, E. G., Hochberg, D., Touroutoglou, A., Quimby, M., & Dickerson, B. C. (2021) · Brain Sciences · doi:10.3390/brainsci11020130 · Cited by 24
Digital Speech Analysis in Progressive Supranuclear Palsy and Corticobasal Syndromes
Parjane, N., Cho, S., Ash, S., Cousins, K. A. Q., Shellikeri, S., Liberman, M., Shaw, L. M., Irwin, D. J., Grossman, M., & Nevler, N. (2021) · Journal of Alzheimer's Disease · doi:10.3233/jad-201132 · Cited by 24
Self-citation
Description of connected speech across different elicitation tasks in the logopenic variant of primary progressive aphasia
Lavoie, M., Black, S. E., Tang‐Wai, D. F., Graham, N. L., Stewart, S., Léonard, C., & Rochon, E. A. (2021) · International Journal of Language & Communication Disorders · doi:10.1111/1460-6984.12660 · Cited by 23
Quantifying grammatical impairments in primary progressive aphasia: Structured language tests and narrative language production
Mack, J. E., Barbieri, E., Weıntraub, S., Mesulam, M. M., & Thompson, C. K. (2020) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2020.107713 · Cited by 23
Linguistic changes in neurodegenerative diseases relate to clinical symptoms
Gumus, M., Koo, M., Studzinski, C. M., Bhan, A., Robin, J., & Black, S. E. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1373341 · Cited by 26
Heterogeneity and overlap in the continuum of linguistic profile of logopenic and semantic variants of primary progressive aphasia: a Profile Analysis based on Multidimensional Scaling study
Santi, G. C., Conca, F., Esposito, V., Polito, C., Caminiti, S. P., Boccalini, C., Morinelli, C., Berti, V., Mazzeo, S., Bessi, V., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01403-0 · Cited by 21
A review of lexical retrieval intervention in primary progressive aphasia and Alzheimer’s disease: mechanisms of change, generalisation, and cognition
Beales, A., Whitworth, A., & Cartwright, J. (2018) · Aphasiology · doi:10.1080/02687038.2018.1491192 · Cited by 20
Added value of multimodal MRI to the clinical diagnosis of primary progressive aphasia variants
Canu, E., Agosta, F., Imperiale, F., Fontana, A., Caso, F., Spinelli, E. G., Magnani, G., Falini, A., Comı, G., & Filippi, M. (2018) · Cortex · doi:10.1016/j.cortex.2018.11.025 · Cited by 22
SECT and MAST: new tests to assess grammatical abilities in primary progressive aphasia
Billette, O. V., Sajjadi, S., Patterson, K., & Nestor, P. (2015) · Aphasiology · doi:10.1080/02687038.2015.1037822 · Cited by 22
The relationship between baseline volume in temporal areas and post-treatment naming accuracy in primary progressive aphasia
Meyer, A. M., Faria, A. V., Tippett, D. C., Hillis, A. E., & Friedman, R. B. (2017) · Aphasiology · doi:10.1080/02687038.2017.1296557 · Cited by 20
Clinical and neuroimaging characteristics of primary progressive aphasia
Tippett, D. C., & Keser, Z. (2022) · Handbook of clinical neurology · doi:10.1016/b978-0-12-823384-9.00016-5 · Cited by 19
Modulation of brain activity by psycholinguistic information during naturalistic speech comprehension and production
Wu, W., Morales, M., Patel, T., Pickering, M. J., & Hoffman, P. (2022) · Cortex · doi:10.1016/j.cortex.2022.08.002 · Cited by 22
Determining stability in connected speech in primary progressive aphasia and Alzheimer’s disease
Beales, A., Whitworth, A., Cartwright, J., Panegyres, P. K., & Kane, R. T. (2018) · International Journal of Speech-Language Pathology · doi:10.1080/17549507.2018.1442498 · Cited by 19
Discriminating nonfluent/agrammatic and logopenic PPA variants with automatically extracted morphosyntactic measures from connected speech
Lukic, S., Fan, Z., García, A. M., Welch, A. E., Ratnasiri, B. M., Wilson, S. M., Henry, M. L., Vonk, J., Deleon, J., Miller, B. L., et al. (2024) · Cortex · doi:10.1016/j.cortex.2023.12.013 · Cited by 19
Frontotemporal dementia. How to deal with its diagnostic complexity?
Antonioni, A., Raho, E. M., Granieri, E., & Koch, G. (2025) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2025.2461758 · Cited by 22
Neuropsychological Assessment of Primary Progressive Aphasia (PPA)
Bettcher, B. M., & Sturm, V. E. (2014) · Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders · doi:10.1044/nnsld24.4.128 · Cited by 18
Silent Pauses and Speech Indices as Biomarkers for Primary Progressive Aphasia
Potagas, C. M., Nikitopoulou, Z., Angelopoulou, G., Kasselimis, D. S., Laskaris, N., Kourtidou, E., Constantinides, V. C., Bougea, A. M., Paraskevas, G. P., Papageorgiou, G., et al. (2022) · Medicina · doi:10.3390/medicina58101352 · Cited by 22
Connected Speech Fluency in Poststroke and Progressive Aphasia: A Scoping Review of Quantitative Approaches and Features
Cordella, C., Filippo, L. D., Kolachalama, V. B., & Kiran, S. (2024) · American Journal of Speech-Language Pathology · doi:10.1044/2024_ajslp-23-00208 · Cited by 16
Lack of Frank Agrammatism in the Nonfluent Agrammatic Variant of Primary Progressive Aphasia
Graham, N. L., Léonard, C., Tang‐Wai, D. F., Black, S. E., Chow, T. W., Scott, C. J. M., McNeely, A. A., Masellis, M., & Rochon, E. A. (2016) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000448944 · Cited by 16
Verb-argument integration in primary progressive aphasia: Real-time argument access and selection
Mack, J. E., Mesulam, M. M., Rogalski, E. J., & Thompson, C. K. (2019) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2019.107192 · Cited by 16
Connected speech markers of amyloid burden in primary progressive aphasia
Slegers, A., Chafouleas, G., Montembeault, M., Bedetti, C., Welch, A. E., Rabinovici, G. D., Langlais, P., Gorno‐Tempini, M. L., & Brambati, S. M. (2021) · Cortex · doi:10.1016/j.cortex.2021.09.010 · Cited by 16
The neural substrates of transdiagnostic cognitive-linguistic heterogeneity in primary progressive aphasia
Ramanan, S., Halai, A. D., García‐Pentón, L., Perry, A., Patel, N., Peterson, K. A., Ingram, R. U., Storey, I., Cappa, S. F., Catricalà, E., et al. (2023) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01350-2 · Cited by 12
A behavioral study of the nature of verb–noun dissociation in the nonfluent variant of primary progressive aphasia
Beber, B. C., Mandelli, M. L., Santos‐Santos, M., Binney, R. J., Miller, B. L., Chaves, M. L. F., Gorno‐Tempini, M. L., & Shapiro, K. A. (2018) · Aphasiology · doi:10.1080/02687038.2018.1461799 · Cited by 14
Pausing before verb production is associated with mild cognitive impairment in Parkinson’s disease
Andrade, E. I. N., Manxhari, C., & Smith, K. M. (2023) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2023.1102024 · Cited by 13
Bilingualism in a Case of the Non-fluent/agrammatic Variant of Primary Progressive Aphasia
Karpathiou, N., Papatriantafyllou, J. D., & Kambanaros, M. (2018) · Frontiers in Communication · doi:10.3389/fcomm.2018.00052 · Cited by 13
Sentence repetition deficits in the logopenic variant of PPA: linguistic analysis of longitudinal and cross-sectional data
Hohlbaum, K., Dressel, K., Lange, I., Wellner, B., Sáez, L. E., Huber, W., Grande, M., Amunts, K., Grodzinsky, Y., & Heim, S. (2018) · Aphasiology · doi:10.1080/02687038.2017.1423271 · Cited by 16
Sentence Comprehension in Primary Progressive Aphasia: A Study of the Application of the Brazilian Version of the Test for the Reception of Grammar (TROG2-Br)
Carthery‐Goulart, M. T., de Oliveira, R., de Almeida, I. J., Campanha, A. C., Souza, D. D. S., Zana, Y., Caramelli, P., & Machado, T. H. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.815227 · Cited by 11
Comprehensive qualitative characterization of linguistic performance profiles in primary progressive aphasia: a multivariate study with FDG-PET
Catricalà, E., Santi, G. C., Polito, C., Conca, F., Esposito, V., Caminiti, S. P., Boccalini, C., Berti, V., Bessi, V., Marcone, A., et al. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.09.001 · Cited by 11
Lexical markers of disordered speech in primary progressive aphasia and ‘Parkinson-plus’ disorders
Henderson, S. K., Ramanan, S., Patterson, K. E., Garrard, P., Patel, N., Peterson, K. A., Halai, A. D., Cappa, S. F., Rowe, J. B., & Ralph, M. A. L. (2024) · Brain Communications · doi:10.1093/braincomms/fcae433 · Cited by 10
Northwestern Anagram Test-Italian (Nat-I) for primary progressive aphasia
Canu, E., Agosta, F., Imperiale, F., Ferraro, P. M., Fontana, A., Magnani, G., Mesulam, M. M., Thompson, C. K., Weıntraub, S., Moro, A., et al. (2019) · Cortex · doi:10.1016/j.cortex.2019.08.007 · Cited by 11
Predicting Cognitive Impairment in Cerebrovascular Disease Using Spoken Discourse Production
Roberts, A., Aveni, K., Basque, S. R., Orange, J. B., McLaughlin, P. M., Ramirez, J., Troyer, A. K., Gutierrez, S., Chen, A., Bartha, R., et al. (2021) · Topics in Language Disorders · doi:10.1097/tld.0000000000000242 · Cited by 10
Auditory Verb Generation Performance Patterns Dissociate Variants of Primary Progressive Aphasia
Lukic, S., Licata, A. E., Weis, E., Bogley, R., Ratnasiri, B. M., Welch, A. E., Hinkley, L. B. N., Miller, Z., García, A. M., Houde, J. F., et al. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.887591 · Cited by 11
The Mini Linguistic State Examination (MLSE): a brief but accurate assessment tool for classifying Primary Progressive AphasiasPreprint
Patel, N., Peterson, K. A., Ingram, R. U., Storey, I., Cappa, S. F., Catricalà, E., Patterson, K. E., Ralph, M. A. L., Rowe, J. B., & Garrard, P. (2020) · medRxiv · doi:10.1101/2020.06.02.20119974 · Cited by 10
A systematic review of the quantitative markers of speech and language of the frontotemporal degeneration spectrum and their potential for cross-linguistic implementation
Coppieters, R., Bouzigues, A., Jiskoot, L. C., Montembeault, M., Tee, B. L., Rohrer, J. D., Bruffaerts, R., Russell, L. L., Foster, P. H., Ferry‐Bolder, E., et al. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105909 · Cited by 9
Diversity of language symptoms in Alzheimrʼs disease
Matsuda, M. (2015) · Higher Brain Function Research · doi:10.2496/hbfr.35.312 · Cited by 3
Baseline Conceptual-Semantic Impairment Predicts Longitudinal Treatment Effects for Anomia in Primary Progressive Aphasia and Alzheimer’s Disease
Meyer, A. M., Snider, S. F., Tippett, D. C., Saloma, R., Turkeltaub, P. E., Hillis, A. E., & Friedman, R. B. (2023) · Aphasiology · doi:10.1080/02687038.2023.2183075 · Cited by 9
A Window Into Functional Communication: Leveraging Naturalistic Speech Samples in Primary Progressive Aphasia
Gallée, J., & Volkmer, A. (2021) · Perspectives of the ASHA Special Interest Groups · doi:10.1044/2021_persp-21-00021 · Cited by 8
Language in behavioral variant frontotemporal dementia: Another stone to be turned in Latin America
Geraudie, A., Díaz Rivera, M., Montembeault, M., & García, A. M. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.702770 · Cited by 7
Neural mechanisms of sentence production: a volumetric study of primary progressive aphasia
Barbieri, E., Lukic, S., Rogalski, E. J., Weıntraub, S., Mesulam, M. M., & Thompson, C. K. (2023) · Cerebral Cortex · doi:10.1093/cercor/bhad470 · Cited by 7
Acoustic and Kinematic Assessment of Motor Speech Impairment in Patients With Suspected Four-Repeat Tauopathies
Cordella, C., Gutz, S. E., Eshghi, M., Stipancic, K. L., Schliep, M. E., Dickerson, B. C., & Green, J. R. (2022) · Journal of Speech Language and Hearing Research · doi:10.1044/2022_jslhr-22-00177 · Cited by 8
Mehrsprachige Pflegebedürftige in deutschen Pflegeheimen und das Projekt UnVergessen
Karl, K. B. (2021) · Springer eBooks · doi:10.1007/978-3-658-33868-8 · Cited by 6
Connected Speech Alterations and Progression in Patients With Primary Progressive Aphasia Variants
Canu, E., Agosta, F., Lumaca, L., Basaia, S., Castelnovo, V., Santicioli, S., Pisano, S., Gatti, E., Lamanuzzi, A., Spinelli, E. G., et al. (2025) · Neurology · doi:10.1212/wnl.0000000000213524 · Cited by 6
Speech Motor Profiles in Primary Progressive Aphasia
Staiger, A., Schroeter, M. L., Ziegler, W., Pino, D., Regenbrecht, F., Schölderle, T., Rieger, T., Riedl, L., Müller‐Sarnowski, F., & Diehl‐Schmid, J. (2023) · American Journal of Speech-Language Pathology · doi:10.1044/2023_ajslp-22-00319 · Cited by 9
Discourse and Conversation Impairments in Patients with Dementia
Themistocleous, C. K. (2023) · Springer eBooks · doi:10.1007/978-3-031-45190-4_3 · Cited by 7
Automatic Analysis of Phonetic Speech Style Dimensions
Ryant, N., & Liberman, M. (2016) · Interspeech (USB) · doi:10.21437/interspeech.2016-1355 · Cited by 6
Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon?
Utianski, R. L., Botha, H., Duffy, J. R., Clark, H. M., Martin, P. R., Butts, A. M., Machulda, M. M., Whitwell, J. L., & Josephs, K. A. (2018) · The Journal of the Acoustical Society of America · doi:10.1121/1.5082210 · Cited by 6
The Discourse Profile in Corticobasal Syndrome: A Comprehensive Clinical and Biomarker Approach
de Almeida, I. J., Silagi, M. L., Carthery‐Goulart, M. T., Parmera, J. B., Cecchini, M. A., Coutinho, A. M., Brucki, S. M. D., Nitríni, R., & Schochat, E. (2022) · Brain Sciences · doi:10.3390/brainsci12121705 · Cited by 5
Apraxia of Speech in the Spontaneous Speech of Nonfluent/Agrammatic Primary Progressive Aphasia
Ash, S., Nevler, N., Irwin, D. J., Shellikeri, S., Rascovsky, K., Shaw, L. M. J., Lee, E. B., Trojanowski, J. Q., & Grossman, M. (2023) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-220089 · Cited by 5
Self-citation
The pattern of phonological, semantic, and circumlocution naming errors for nouns and verbs in primary progressive aphasia
Meyer, A. M., Snider, S. F., Tippett, D. C., Saloma, R., Faria, A. V., Turkeltaub, P. E., Hillis, A. E., & Friedman, R. B. (2024) · Aphasiology · doi:10.1080/02687038.2024.2361961 · Cited by 5
The Neurofunctional Correlates of Morphosyntactic and Thematic Impairments in Aphasia: A Systematic Review and Meta-analysis
Beber, S., Bontempi, G., Miceli, G., & Tettamanti, M. (2024) · Neuropsychology Review · doi:10.1007/s11065-024-09648-0 · Cited by 7

Authors: Ash, S., Evans, E., O'Shea, J., Powers, J., Boller, A., Weinberg, D., Haley, J., McMillan, C., Irwin, D. J., Rascovsky, K., & Grossman, M.
Affiliations: University of Pennsylvania (US)
ORCID: Ash, Sharon
Powers, John
Weinberg, Danielle
McMillan, Corey
Irwin, David J.
Grossman, Murray
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2013-07-23
Volume: 81
Issue: 4
Pages: 329-336
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.0b013e31829c5d0e
PMC: PMC3772830
OpenAlex: W2100387103
Cited by: 171
References: 38
Citations by year: 2026: 14 · 2025: 18 · 2024: 16 · 2023: 16 · 2022: 22 · 2021: 18 · 2020: 11 · 2019: 5 · 2018: 16 · 2017: 12 · 2016: 9 · 2015: 10 · 2014: 3 · 2013: 1
FWCI: 5.43
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Neurology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Wyncote Foundation
National Institutes of Health
National Institute on Aging (R01AG038490, R01AG015116, P01AG017586, AG038490, AG032953, AG-017586, AG015116, P01AG032953, T32AG000255)
National Institute of Neurological Disorders and Stroke (NS053488, P50NS053488, NS044266, R01NS044266)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
Health Sciences › Medicine › Clinical Neurology › Amyotrophic Lateral Sclerosis Research
Keywords: primary progressive aphasia, differential diagnosis, logopenic variant PPA, semantic variant PPA, picture description task, speech production, grammaticality, speech rate, word retrieval, disfluency, false starts, gray matter atrophy, white matter fractional anisotropy
MeSH terms: Aged, Aged, 80 and over, Atrophy, Brain, Brain Mapping, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Middle Aged, Semantics, Speech, Aphasia, Primary Progressive, Frontotemporal Dementia

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Differentiating primary progressive aphasias in a brief sample of connected speech

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks