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Cited by 572

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Depression, intellectual impairment, and Parkinson disease

Mayeux, Richard, Stern, Yaakov, Rosen, Jeffrey, Leventhal, Jean·1981·Neurology
DOI 10.1212/wnl.31.6.645
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Abstract

To determine the prevalence of depression in Parkinson disease (PD) we evaluated 55 consecutive patients without dementia and 31 of their spouses. All subjects completed the Beck depression inventory and a quantitative mini-mental state examination. Using the Beck criteria, 47% of the patients and 12% of the spouses rated themselves as significantly depressed. Mental state scores were significantly lower in the patients. There was a correlation between the severity of depression and cognitive impairment, particularly for calculation, digit span, and visuomotor skills. The severity of parkinsonism, particularly bradykinesia, also paralleled cognition. There was a slight but significant relationship between parkinsonism and depression. These results confirm the high incidence of depression in PD, and suggest that depression in Parkinson patients may be accompanied by mild intellectual impairment and inattention which is independent of the severity of the illness.

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Metadata

Authors
Mayeux, R., Stern, Y., Rosen, J., & Leventhal, J.
Venue
Neurology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
1981-06
Volume
31
Issue
6
Pages
645-645
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
DOI
10.1212/wnl.31.6.645
OpenAlex
W2028064682
Cited by
572
References
0
FWCI
14.93
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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