Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham Study
Abstract
We determined the prevalence of dementia and probable senile dementia of the Alzheimer type (SDAT) for biennial Exam 17 of the Framingham cohort (1982/1983). The prevalence of dementia was 30.5/1,000 for men and 48.2/1,000 for women and increased with advancing age. Cases of probable SDAT constituted 55.6% of all dementia cases. THe prevalence of SDAT was 11.7/1,000 for men and 30.1/1,000 for women and also increased with advancing age. Prevalence of dementia and probable SDAT were greater for women than men. The female:male ratio of prevalence for cohort members 75 years of age and older was 1.8 for all cases of dementia and 2.8 for cases of probable SDAT.
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Dementia prevalence in SATSA and OCTO-Twin is similar to that reported in the Kungsholmen study in Sweden and the Framingham study in the U.S.
“Prevalence rates of dementia in SATSA and OCTO-Twin have been found to resemble other similar studies such as the Kungsholmen study25 in Sweden, and the Framingham study26 in the U.S.”
From Overweight in midlife and risk of dementia: a 40-year follow-up study (2009) · cites this paper as [26]
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BackgroundResult
- Authors
- Bachman, D. L., Wolf, P. A., Linn, R., Knoefel, J. E., CobbS, J., Belanger, A., D'Agostino, R. B., & White, L. R.
- Affiliations
- Boston University (US)
- From the Department of Neurology (Drs. Bachman, Wolf, Linn, and Knoefel), Boston University School of Medicine, Boston, MA; Department of Mathematics (J. Cobb, A. Belanger, and Dr. D'Agostino), Boston University, Boston, MA, and Epidemiology, Demography, and Biometry Program (Dr. White), National Institute on Aging, Bethesda, MD.
- Venue
- Neurology
- Published
- 1992-01
- Volume
- 42
- Issue
- 1
- Pages
- 115-115
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2017059429
- Cited by
- 527
- References
- 0
- Citations by year
- 2026: 1 · 2025: 14 · 2024: 9 · 2023: 11 · 2022: 15 · 2021: 14 · 2020: 11 · 2019: 11 · 2018: 11 · 2017: 13 · 2016: 14 · 2015: 12 · 2014: 15 · 2013: 9 · 2012: 17
- FWCI
- 13.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (1R01-AG-08122-01, R01AG008122)
- National Heart, Lung, and Blood Institute (N01-HC-38038)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Keywords
- dementia prevalence, Alzheimer's disease, sex differences, older adults
- MeSH terms
- Adult, Age Factors, Aged, Aged, 80 and over, Alzheimer Disease, Dementia, Female, Humans, Male, Mental Status Schedule, Middle Aged, Sex Factors, Cohort Studies, Prevalence
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