The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions
Open accessAbstract
High levels of interspecies conservation characterise all signal transduction cascades and demonstrate the significance of these pathways over evolutionary time. Here, we review advances in the field of JAK/STAT signalling, focusing on recent developments in Drosophila. In particular, recent results from genetic and genome-wide RNAi screens, as well as studies into the developmental roles played by this pathway, highlight striking levels of physical and functional conservation in processes such as cellular proliferation, immune responses and stem cell maintenance. These insights underscore the value of model organisms for improving our understanding of this human disease-relevant pathway.
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Cites
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Vertebrate-Type Intron-Rich Genes in the Marine Annelid Platynereis dumerilii
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Cited by
An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense
Souza-Neto, J. A., Sim, S., & Dimopoulos, G. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905006106 · Cited by 573
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Neuromodulation by the immune system: a focus on cytokines
Salvador, A. F., de Lima, K. A., & Kipnis, J. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-021-00508-z · Cited by 389
Signaling Mechanisms Controlling Cell Fate and Embryonic Patterning
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Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis
Larson, K., Yan, S.-J., Tsurumi, A., Liu, J., Zhou, J., Gaur, K., Guo, D., Eickbush, T. H., & Li, W. X. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002473 · Cited by 284
Canonical and non-canonical JAK–STAT signaling
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Simulation-based model selection for dynamical systems in systems and population biology
Toni, T., & Stumpf, M. P. H. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp619 · Cited by 260
The stem cell niche: lessons from the Drosophila testis
de Cuevas, M., & Matunis, E. L. (2011) · Development · doi:10.1242/dev.056242 · Cited by 263
JAK-STAT Signaling in Stem Cells
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Metadata
- Authors
- Arbouzova, N. I., & Zeidler, M. P.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2006-07-15
- Volume
- 133
- Issue
- 14
- Pages
- 2605-2616
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1998148517
- Cited by
- 397
- References
- 7
- FWCI
- 9.61
- Type
- journal article
- Language
- en
- Open access
- bronze
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