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Cited by 825

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Making muscle: skeletal myogenesis in vivo and in vitro

Chal, Jérome, Pourquié, Olivier·2017·Development

Abstract

Skeletal muscle is the largest tissue in the body and loss of its function or its regenerative properties results in debilitating musculoskeletal disorders. Understanding the mechanisms that drive skeletal muscle formation will not only help to unravel the molecular basis of skeletal muscle diseases, but also provide a roadmap for recapitulating skeletal myogenesis in vitro from pluripotent stem cells (PSCs). PSCs have become an important tool for probing developmental questions, while differentiated cell types allow the development of novel therapeutic strategies. In this Review, we provide a comprehensive overview of skeletal myogenesis from the earliest premyogenic progenitor stage to terminally differentiated myofibers, and discuss how this knowledge has been applied to differentiate PSCs into muscle fibers and their progenitors in vitro.

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Crossref · 10.1242/dev.151035

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Metadata

Authors
Chal, J., & Pourquié, O.
Venue
Development
Published
2017-06-15
Volume
144
Issue
12
Pages
2104-2122
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
OpenAlex
W2719903628
Cited by
825
References
21
FWCI
20.96
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.