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Trend of coronary heart disease and its relationship to risk factors in a Japanese population: A 26-year follow-up, Hiroshima/Nagasaki study.
Open accessAbstract
The incidence of coronary heart disease (CHD) was determined from a 26-year follow-up study of a fixed population of 19,961 subjects. The study also examined secular trends and relationship to risk factors. The age-adjusted incidence of myocardial infarction was found to have remained almost constant during this 26-year follow-up period, averaging 2.1/1,000 person-years in men and 0.79/1,000 person-years in women. An accurate trend of angina pectoris was difficult to evaluate in this study. Both age and elevated systolic blood pressure were confirmed to be important and independent risk factors. The risk of developing CHD was found to increase linearly with respect to systolic blood pressure. An increased risk was also observed in subjects with diastolic blood pressure of 110 mmHg or higher. Serum cholesterol and cigarette smoking were additional independent risk factors, indicating that the so-called three major risk factors for CHD were all confirmed in this Japanese population of both men and women.
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“a number of cohort studies conducted in Japan have reported an increase in the incidence and mortality rates of CAD following an elevation in TC level48–54).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [48]
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Metadata
- Authors
- KODAMA, K., SASAKI, H., & SHIMIZU, Y.
- Affiliations
- Radiation Effects Research Foundation (JP)
- Venue
- Japanese Circulation Journal
- Publisher
- Japanese Circulation Society
- Published
- 1990
- Volume
- 54
- Issue
- 4
- Pages
- 414-421
- ISSN
- 0047-1828 (ISSN-L)
- 1347-4839
- OpenAlex
- W2069806183
- Cited by
- 135
- References
- 11
- Citations by year
- 2024: 1 · 2023: 2 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 6 · 2016: 3 · 2015: 2 · 2013: 8 · 2012: 7
- FWCI
- 0.80
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Japanese Circulation Journal-english Edition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- coronary artery disease, myocardial infarction, angina pectoris, incidence, secular trends, cardiovascular risk factors, systolic blood pressure, diastolic blood pressure, serum cholesterol, cigarette smoking, sex differences, Japanese population
- MeSH terms
- Adult, Aged, Blood Pressure, Cholesterol, Coronary Disease, Electrocardiography, Female, Glycosuria, Humans, Japan, Male, Middle Aged, Risk Factors, Smoking
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