Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genes

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482 · see citing works

Nonparametric Estimation from Incomplete Observations

Kaplan, E. L., & Meier, P. (1992) · Springer series in statistics · doi:10.1007/978-1-4612-4380-9_25 · Cited by 45,232 · see citing works

Gene Ontology: tool for the unification of biology

Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., Davis, A. P., Dolinski, K., Dwight, S. S., Eppig, J. T., et al. (2000) · Nature Genetics · doi:10.1038/75556 · Cited by 43,206 · see citing works

Nonparametric Estimation from Incomplete Observations

Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158 · see citing works

THE GENETICS OF CAENORHABDITIS ELEGANS

Brenner, S. (1974) · Genetics · doi:10.1093/genetics/77.1.71 · Cited by 14,984 · see citing works

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

Reinhart, B. J., Slack, F. J., Basson, M., Pasquinelli, A. E., Bettinger, J. C., Rougvie, A. E., Horvitz, H. R., & Ruvkun, G. (2000) · Nature · doi:10.1038/35002607 · Cited by 4,989 · see citing works

Identification of Novel Genes Coding for Small Expressed RNAs

Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science · doi:10.1126/science.1064921 · Cited by 4,956 · see citing works

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K., Uematsu, S., Jung, A., Kawai, T., Ishii, K. J., et al. (2006) · Nature · doi:10.1038/nature04734 · Cited by 3,888 · see citing works

An Abundant Class of Tiny RNAs with Probable Regulatory Roles in <i>Caenorhabditis elegans</i>

Lau, N. C., Lim, L. P., Weinstein, E. G., & Bartel, D. P. (2001) · Science · doi:10.1126/science.1065062 · Cited by 2,713 · see citing works

An Extensive Class of Small RNAs in <i>Caenorhabditis elegans</i>

Lee, R. C., & Ambros, V. (2001) · Science · doi:10.1126/science.1065329 · Cited by 2,358 · see citing works

[C. elegans: of neurons and genes].

Gally, C., & Bessereau, J. (2003) · Medecine sciences : M/S · doi:10.1051/medsci/20031967725 · Cited by 2,194 · see citing works

A Plant miRNA Contributes to Antibacterial Resistance by Repressing Auxin Signaling

Navarro, L., Dunoyer, P., Jay, F., Arnold, B., Dharmasiri, N., Estelle, M. A., Voinnet, O., & Jones, J. D. G. (2006) · Science · doi:10.1126/science.1126088 · Cited by 1,976 · see citing works

Innate immune recognition of viral infection

Kawai, T., & Akira, S. (2006) · Nature Immunology · doi:10.1038/ni1303 · Cited by 1,899 · see citing works

A Model-Based Background Adjustment for Oligonucleotide Expression Arrays

Wu, Z. J., Irizarry, R. A., Gentleman, R. C., Martínez-Murillo, F., & Spencer, F. A. (2004) · Journal of the American Statistical Association · doi:10.1198/016214504000000683 · Cited by 1,717 · see citing works

Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing

Grishok, A., Pasquinelli, A. E., Conte, D., Li, N., Parrish, S., Ha, I., Baillie, D. L., Fire, A., Ruvkun, G., & Mello, C. C. (2001) · Cell · doi:10.1016/s0092-8674(01)00431-7 · Cited by 1,600 · see citing works

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in <i>C. elegans</i>

Ketting, R. F., Fischer, S. E. J., Bernstein, E., Sijen, T., Hannon, G. J., & Plasterk, R. H. A. (2001) · Genes &amp; Development · doi:10.1101/gad.927801 · Cited by 1,527 · see citing works

Regulation by let-7 and lin-4 miRNAs Results in Target mRNA Degradation

Bagga, S., Bracht, J. R., Hunter, S. E., Massirer, K. B., Holtz, J., Eachus, R., & Pasquinelli, A. E. (2005) · Cell · doi:10.1016/j.cell.2005.07.031 · Cited by 1,347 · see citing works

The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans

Tabara, H., Sarkissian, M., Kelly, W. G., Fleenor, J., Grishok, A., Timmons, L., Fire, A. Z., & Mello, C. C. (1999) · Cell · doi:10.1016/s0092-8674(00)81644-x · Cited by 1,283 · see citing works

Intracellular pattern recognition receptors in the host response

Meylan, E., Tschopp, J., & Karin, M. (2006) · Nature · doi:10.1038/nature04946 · Cited by 1,196 · see citing works

Large-Scale Sequencing Reveals 21U-RNAs and Additional MicroRNAs and Endogenous siRNAs in C. elegans

Ruby, J. G., Jan, C. H., Player, C. M., Axtell, M. J., Lee, W., Nusbaum, C., Ge, H., & Bartel, D. P. (2006) · Cell · doi:10.1016/j.cell.2006.10.040 · Cited by 967 · see citing works

A Role for the RNase III Enzyme DCR-1 in RNA Interference and Germ Line Development in Caenorhabditis elegans

Knight, S. W., & Bass, B. (2001) · Science · doi:10.1126/science.1062039 · Cited by 844 · see citing works

RNAi-mediated pathways in the nucleus

Matzke, M. A., & Birchler, J. A. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1500 · Cited by 840 · see citing works

RNA Interference Directs Innate Immunity Against Viruses in Adult Drosophila

Wang, X.-H., Aliyari, R., Li, W.-X., Li, H.-W., Kim, K., Carthew, R. W., Atkinson, P. W., & Ding, S. (2006) · Science · doi:10.1126/science.1125694 · Cited by 726 · see citing works

p38 MAPK Regulates Expression of Immune Response Genes and Contributes to Longevity in C. elegans

Troemel, E. R., Chu, S. W. L., Reinke, V., Lee, S. S., Ausubel, F. M., & Kim, D. H. (2005) · PLoS Genetics · doi:10.1371/journal.pgen.0020183 · Cited by 675 · see citing works

Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi

Yigit, E., Batista, P. J., Bei, Y., Pang, K. M., Chen, C.-C. G., Tolia, N. H., Joshua‐Tor, L., Mitani, S., Simard, M. J., & Mello, C. C. (2006) · Cell · doi:10.1016/j.cell.2006.09.033 · Cited by 652 · see citing works

Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans

Pak, J., & Fire, A. Z. (2006) · Science · doi:10.1126/science.1132839 · Cited by 631 · see citing works

The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogasterPreprint

van Rij, R. P., Saleh, M., Berry, B., Foo, C. K., Houk, A. R., Antoniewski, C., & Andino, R. (2006) · Genes & Development · doi:10.1101/gad.1482006 · Cited by 597 · see citing works

MicroRNAs and Other Tiny Endogenous RNAs in C. elegans

Ambros, V., Lee, R. C., Lavanway, A., Williams, P. T., & Jewell, D. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00287-2 · Cited by 586 · see citing works

Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila

Galiana-Arnoux, D., Dostert, C., Schneemann, A., Hoffmann, J. A., & Imler, J. (2006) · Nature Immunology · doi:10.1038/ni1335 · Cited by 566 · see citing works

The dsRNA Binding Protein RDE-4 Interacts with RDE-1, DCR-1, and a DExH-Box Helicase to Direct RNAi in C. elegans

Tabara, H., Yigit, E., Siomi, H., & Mello, C. C. (2002) · Cell · doi:10.1016/s0092-8674(02)00793-6 · Cited by 542 · see citing works

TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM

Couillault, C., Pujol, N., Reboul, J., Ehret‐Sabatier, L., Guichou, J., Kohara, Y., & Ewbank, J. J. (2004) · Nature Immunology · doi:10.1038/ni1060 · Cited by 482 · see citing works

Inducible Antibacterial Defense System in C. elegans

Mallo, G. V., Kurz, C. L., Couillault, C., Pujol, N., Granjeaud, S., Kohara, Y., & Ewbank, J. J. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00928-4 · Cited by 478 · see citing works

The Yin and Yang of type I interferon activity in bacterial infection

Decker, T., Müller, M. M., & Stockinger, S. (2005) · Nature reviews. Immunology · doi:10.1038/nri1684 · Cited by 468 · see citing works

A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans.

Pujol, N., Link, E. M., Liu, L. X., Kurz, C., Alloing, G., Tan, M.-W., Ray, K. P., Solari, R. C. E., Johnson, C. D., & Ewbank, J. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00241-x · Cited by 455 · see citing works

Genome-wide germline-enriched and sex-biased expression profiles in Caenorhabditis elegans

Reinke, V., Gil, I. S., Ward, S. F., & Kazmer, K. (2003) · Development · doi:10.1242/dev.00914 · Cited by 453 · see citing works

A Genome-Wide Map of Conserved MicroRNA Targets in C. elegans

Lall, S., Grün, D., Krek, A., Chen, K., Wang, Y.-L., Dewey, C. N., Sood, P., Colombo, T., Bray, N., MacMenamin, P., et al. (2006) · Current Biology · doi:10.1016/j.cub.2006.01.050 · Cited by 421 · see citing works

Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways

Duchaîne, T. F., Wohlschlegel, J. A., Kennedy, S. G., Bei, Y., Conte, D., Pang, K. M., Brownell, D. R., Harding, S. J., Mitani, S., Ruvkun, G., et al. (2006) · Cell · doi:10.1016/j.cell.2005.11.036 · Cited by 392 · see citing works

Analysis of the constancy of DNA sequences during development and evolution of the nematode Caenorhabditis elegans.

Emmons, S. W., Klass, M. R., & Hirsh, D. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.3.1333 · Cited by 385 · see citing works

RNA interference is an antiviral defence mechanism in Caenorhabditis elegans

Wilkins, C. R., Dishongh, R., Moore, S. C., Whitt, M. A., Chow, M., & Machaca, K. (2005) · Nature · doi:10.1038/nature03957 · Cited by 354 · see citing works

Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins

Huffman, D. L., Abrami, L., Šášik, R., Corbeil, J., van der Goot, F. G., & Aroian, R. V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404073101 · Cited by 312 · see citing works

A conserved role for a GATA transcription factor in regulating epithelial innate immune responses

Shapira, M., Hamlin, B. J., Rong, J., Chen, K., Ronen, M., & Tan, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603424103 · Cited by 296 · see citing works

Silence from within: Endogenous siRNAs and miRNAs

Sontheimer, E. J., & Carthew, R. W. (2005) · Cell · doi:10.1016/j.cell.2005.06.030 · Cited by 291 · see citing works

The Temporal Patterning MicroRNA let-7 Regulates Several Transcription Factors at the Larval to Adult Transition in C. elegans

Großhans, H., Johnson, T., Reinert, K. L., Gerstein, M., & Slack, F. J. (2005) · Developmental Cell · doi:10.1016/j.devcel.2004.12.019 · Cited by 260 · see citing works

BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments

Al‐Shahrour, F., Mínguez, P., Vaquerizas, J. M., Conde, L., & Dopazo, J. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki456 · Cited by 254 · see citing works

Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection ofC. eleganswithM. nematophilumPreprint

O’Rourke, D., Baban, D. F., Demidova, M., Mott, R., & Hodgkin, J. (2006) · Genome Research · doi:10.1101/gr.50823006 · Cited by 246 · see citing works

Evolution of the innate immune system: the worm perspective

Schulenburg, H., Kurz, C. L., & Ewbank, J. J. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.0125.x · Cited by 229 · see citing works

Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans

Lee, R. C., Hammell, C. M., & Ambros, V. (2006) · RNA · doi:10.1261/rna.2231506 · Cited by 211 · see citing works

Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells

Schmitter, D., Filkowski, J. N., Sewer, A., Pillai, R. S., Oakeley, E. J., Zavolan, M., Svoboda, P., & Filipowicz, W. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl646 · Cited by 208 · see citing works

An antiviral role for the RNA interference machinery in Caenorhabditis elegans

Schott, D. H., Cureton, D. K., Whelan, S. P. J., & Hunter, C. P. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507123102 · Cited by 184 · see citing works

X-Chromosome dosage compensation

Meyer, B. J. (2005) · WormBook · doi:10.1895/wormbook.1.8.1 · Cited by 184 · see citing works

A Model Based Background Adjustment for Oligonucleotide Expression ArraysPreprint

Wu, Z. J., Irizarry, R. A., Gentleman, R. C., Murillo, F., & Spencer, F. A. (2004) · RePEc: Research Papers in Economics · Cited by 153 · see citing works

Distinct roles for RDE-1 and RDE-4 during RNA interference in Caenorhabditis elegans.

Parrish, S., & Fire, A. Z. (2001) · PubMed · Cited by 150 · see citing works

Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee

Lü, J., & Wu, C. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500436102 · Cited by 141 · see citing works

Global Effects on Gene Expression in Fission Yeast by Silencing and RNA Interference Machineries

Hansen, K., Burns, G., Mata, J., Volpe, T. A., Martienssen, R. A., Bähler, J., & Thon, G. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.2.590-601.2005 · Cited by 137 · see citing works

RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA

Parker, G. S., Eckert, D. M., & Bass, B. (2006) · RNA · doi:10.1261/rna.2338706 · Cited by 124 · see citing works

GATA Transcription Factor Required for Immunity to Bacterial and Fungal Pathogens

Kerry, S. E., TeKippe, M., Gaddis, N., & Aballay, A. (2006) · PLoS ONE · doi:10.1371/journal.pone.0000077 · Cited by 100 · see citing works

EGO-1, a Putative RNA-Dependent RNA Polymerase, Is Required for Heterochromatin Assembly on Unpaired DNA during C. elegans Meiosis

Maine, E. M., Hauth, J., Ratliff, T. M., Vought, V. E., She, X., & Kelly, W. G. (2005) · Current Biology · doi:10.1016/j.cub.2005.09.049 · Cited by 89 · see citing works

The Caenorhabditis elegans unc-32 Gene Encodes Alternative Forms of a Vacuolar ATPase aSubunit

Pujol, N., Bonnerot, C., Ewbank, J. J., Kohara, Y., & Thierry‐Mieg, D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009451200 · Cited by 76 · see citing works

Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer

Merritt, W. M., Lin, Y. G., Han, L. Y., Kamat, A. A., Spannuth, W. A., Schmandt, R. E., Urbauer, D. L., Pennacchio, L. A., Cheng, J., Nick, A. M., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0803785 · Cited by 710 · see citing works

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

Walther, D. M., Kasturi, P., Zheng, M., Pinkert, S., Vecchi, G., Ciryam, P., Morimoto, R. I., Dobson, C. M., Vendruscolo, M., Mann, M., et al. (2015) · Cell · doi:10.1016/j.cell.2015.03.032 · Cited by 569 · see citing works

The evolution of RNAi as a defence against viruses and transposable elements

Obbard, D. J., Gordon, K. H. J., Buck, A. H., & Jiggins, F. M. (2008) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2008.0168 · Cited by 521 · see citing works

X‐chromosome‐located microRNAs in immunity: Might they explain male/female differences?

Pinheiro, I., Dejager, L., & Libert, C. (2011) · BioEssays · doi:10.1002/bies.201100047 · Cited by 273 · see citing works

Distinct Phases of siRNA Synthesis in an Endogenous RNAi Pathway in C. elegans Soma

Gent, J. I., Lamm, A. T., Pavelec, D. M., Maniar, J. M., Parameswaran, P., Li, T., Kennedy, S. G., & Fire, A. Z. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.01.012 · Cited by 197 · see citing works

miRNA regulation of cytokine genes

Asirvatham, A. J., Magner, W. J., & Tomasi, T. B. (2009) · Cytokine · doi:10.1016/j.cyto.2008.11.010 · Cited by 161 · see citing works

Endogenous RNAi pathways in C. elegans

Billi, A. C. (2014) · WormBook · doi:10.1895/wormbook.1.170.1 · Cited by 155 · see citing works

dsRNA Binding Properties of RDE-4 and TRBP Reflect Their Distinct Roles in RNAi

Parker, G. S., Maity, T., & Bass, B. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.10.002 · Cited by 94 · see citing works

Natural RNA interference directs a heritable response to the environment

Schott, D. H., Yanai, I., & Hunter, C. P. (2014) · Scientific Reports · doi:10.1038/srep07387 · Cited by 93 · see citing works

Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegansPreprint

Sarkies, P., Ashe, A., Pen, J. L., McKie, M. A., & Miska, E. A. (2013) · Genome Research · doi:10.1101/gr.153296.112 · Cited by 88 · see citing works

Small Molecule Inhibition of RISC Loading

Tan, G. S., Chiu, C.-H., Garchow, B. G., Metzler, D., Diamond, S. L., & Kiriakidou, M. (2011) · ACS Chemical Biology · doi:10.1021/cb200253h · Cited by 85 · see citing works

WormBase 2007

Rogers, A., Antoshechkin, I. A., Bieri, T. A., Blasiar, D., Bastiani, C. A., Canaran, P., Chan, J., Chen, W. J., Davis, P. A., Fernandes, J. D., et al. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm975 · Cited by 84 · see citing works

Biology and Mechanisms of Short RNAs in Caenorhabditis elegans

Grishok, A. (2013) · Advances in genetics · doi:10.1016/b978-0-12-407675-4.00001-8 · Cited by 75 · see citing works

A starvation-induced noncoding RNA modulates expression of Dicer-regulated genes

Hellwig, S., & Bass, B. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805118105 · Cited by 78 · see citing works

MicroRNA–Directed siRNA Biogenesis in Caenorhabditis elegans

Correa, R. L., Steiner, F. A., Berezikov, E., & Ketting, R. F. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1000903 · Cited by 74 · see citing works

Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB

Tang, K., Ren, H., Cao, J., Zeng, G.-L., Xie, J., Chen, M., Wang, L., & He, C. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200801169 · Cited by 73 · see citing works

The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis

Deffit, S. N., Yee, B. A., Manning, A. C., Rajendren, S., Vadlamani, P., Wheeler, E. C., Domissy, A., Washburn, M. C., Yeo, G. W.-M., & Hundley, H. A. (2017) · eLife · doi:10.7554/elife.28625 · Cited by 65 · see citing works

Genetic and molecular analysis of nematode–microbe interactions

Tan, M.-W., & Shapira, M. (2011) · Cellular Microbiology · doi:10.1111/j.1462-5822.2011.01570.x · Cited by 52 · see citing works

Associations between transcriptional changes and protein phenotypes provide insights into immune regulation in corals

Fuess, L. E., Pinzón, J. H., Weil, E. F., & Mydlarz, L. D. (2016) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2016.04.017 · Cited by 59 · see citing works

The MicroRNA mir-71 Inhibits Calcium Signaling by Targeting the TIR-1/Sarm1 Adaptor Protein to Control Stochastic L/R Neuronal Asymmetry in C. elegans

Hsieh, Y., Chang, C., & Chuang, C. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002864 · Cited by 58 · see citing works

Systematic Analysis of Tissue-Restricted miRISCs Reveals a Broad Role for MicroRNAs in Suppressing Basal Activity of the C. elegans Pathogen Response

Kudlow, B. A., Zhang, L., & Han, M. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.03.011 · Cited by 57 · see citing works

The Nematode Caenorhabditis elegans as a Model Organism to Study Metabolic Effects of ω-3 Polyunsaturated Fatty Acids in Obesity

Bouyanfif, A., Jayarathne, S., Koboziev, I., & Moustaïd‐Moussa, N. (2018) · Advances in Nutrition · doi:10.1093/advances/nmy059 · Cited by 54 · see citing works

A Glimpse of “Dicer Biology” Through the Structural and Functional Perspective

Paturi, S., & Deshmukh, M. V. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.643657 · Cited by 55 · see citing works

Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans

Lehrbach, N. J., Castro, C., Murfitt, K. J., Abreu‐Goodger, C., Griffin, J. L., & Miska, E. A. (2012) · RNA · doi:10.1261/rna.035402.112 · Cited by 54 · see citing works

Genome-wide profiling of the C. elegans dsRNAome

Whipple, J. M., Youssef, O. A., Aruscavage, P. J., Nix, D. A., Hong, C., Johnson, W. E., & Bass, B. (2015) · RNA · doi:10.1261/rna.048801.114 · Cited by 50 · see citing works

The art of microRNA: Various strategies leading to gene silencing via an ancient pathway

Tang, G., Tang, X., Mendu, V., Tang, X., Jia, X., CHEN, Q., & HE, L. (2008) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2008.06.006 · Cited by 45 · see citing works

C. elegans Dicer interacts with the P-granule component GLH-1 and both regulate germline RNPs

Beshore, E. L., McEwen, T. J., Jud, M. C., Marshall, J., Schisa, J. A., & Bennett, K. L. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2010.12.005 · Cited by 43 · see citing works

Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis

Gerbasi, V. R., Preall, J. B., Golden, D. E., Powell, D. W., Cummins, T. D., & Sontheimer, E. J. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1009781108 · Cited by 39 · see citing works

Alterations in gene expression in Caenorhabditis elegans associated with organophosphate pesticide intoxication and recovery

Lewis, J. A., Gehman, E. A., Baer, C. E., & Jackson, D. A. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-291 · Cited by 38 · see citing works

RNA interference and retinoblastoma-related genes are required for repression of endogenous siRNA targets in Caenorhabditis elegans

Grishok, A., Hoersch, S., & Sharp, P. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810589105 · Cited by 33 · see citing works

New Role for DCR-1/Dicer in Caenorhabditis elegans Innate Immunity against the Highly Virulent Bacterium Bacillus thuringiensis DB27

Iatsenko, I., Sinha, A., Rödelsperger, C., & Sommer, R. J. (2013) · Infection and Immunity · doi:10.1128/iai.00700-13 · Cited by 28 · see citing works

Strength in numbers

Simonsen, K. T., Gallego, S. F., Færgeman, N. J., & Kallipolitis, B. H. (2012) · Virulence · doi:10.4161/viru.21906 · Cited by 28 · see citing works

On the nature of in vivo requirements forrde-4in RNAi and developmental pathways inC. elegans

Blanchard, D., Parameswaran, P., Lopez-Molina, J., Gent, J. I., Fleenor, J., & Fire, A. Z. (2011) · RNA Biology · doi:10.4161/rna.8.3.14657 · Cited by 28 · see citing works

cel-mir-237 and its homologue, hsa-miR-125b, modulate the cellular response to ionizing radiation

Metheetrairut, C., Adams, B. D., Nallur, S. V., Weidhaas, J. B., & Slack, F. J. (2016) · Oncogene · doi:10.1038/onc.2016.222 · Cited by 25 · see citing works

Literature review of baseline information to support the risk assessment of RNAi‐based GM plants

Pačes, J., Nič, M., Novotny, T., & Svoboda, P. (2017) · EFSA Supporting Publications · doi:10.2903/sp.efsa.2017.en-1246 · Cited by 26 · see citing works

Transcription regulatory networks in Caenorhabditis elegans inferred through reverse-engineering of gene expression profiles constitute biological hypotheses for metazoan development

Vermeirssen, V., Joshi, A., Michoel, T., Bonnet, É., Casneuf, T., & de Peer, Y. V. (2009) · Molecular BioSystems · doi:10.1039/b908108a · Cited by 24 · see citing works

Correction: Characterization of PUD-1 and PUD-2, Two Proteins Up-Regulated in a Long-Lived daf-2 Mutant

Ding, Y., Du, Y., Luo, S. C., Li, Y., Li, T., Yoshina, S., Wang, X., Klage, K., Mitani, S., Ye, K., et al. (2013) · PLoS ONE · doi:10.1371/annotation/6b155146-de73-4733-83b0-62224d84717e · Cited by 21 · see citing works

Recent advances in understanding microRNA function and regulation in C. elegans

Kotagama, K., & McJunkin, K. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.03.011 · Cited by 19 · see citing works

Consolidating multiple evolutionary theories of ageing suggests a need for new approaches to study genetic contributions to ageing decline

Slade, L., Etheridge, T., & Szewczyk, N. J. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102456 · Cited by 13 · see citing works

Characterization of PUD-1 and PUD-2, Two Proteins Up-Regulated in a Long-Lived daf-2 Mutant

Ding, Y., Du, Y., Luo, S., Li, Y., Li, T., Yoshina, S., Wang, X., Klage, K., Mitani, S., Ye, K., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067158 · Cited by 13 · see citing works

A Proteomic Analysis Provides Novel Insights into the Stress Responses of Caenorhabditis elegans towards Nematicidal Cry6A Toxin from Bacillus thuringiensis

Wang, B., Wang, H., Xiong, J., Zhou, Q., Wu, H. G., Xia, L., Li, L., & Yu, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-14428-3 · Cited by 13 · see citing works

RNA interference of an orthologue of Dicer of Meloidogyne incognita alludes to the gene’s importance in nematode development

Iqbal, S., Jones, M. G. K., & Fosu‐Nyarko, J. (2021) · Scientific Reports · doi:10.1038/s41598-021-90363-8 · Cited by 9 · see citing works

Neuronal Migration Is Regulated by Endogenous RNAi and Chromatin-Binding Factor ZFP-1/AF10 in Caenorhabditis elegans

Kennedy, L. M., & Grishok, A. (2014) · Genetics · doi:10.1534/genetics.114.162917 · Cited by 9 · see citing works

Small DNA Pieces in C. elegans Are Intermediates of DNA Fragmentation during Apoptosis

Aruscavage, P. J., Hellwig, S., & Bass, B. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011217 · Cited by 8 · see citing works

Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes

Shugarts Devanapally, N. M., Sathya, A., Yi, A. L., Chan, W. M., Marre, J. A., & Jose, A. M. (2025) · eLife · doi:10.7554/elife.99149.3 · Cited by 6 · see citing works

Endogenous RNAi and adaptation to environment in C. elegans

Grishok, A. (2012) · Worm · doi:10.4161/worm.19538 · Cited by 3 · see citing works

DOT-1.1 (DOT1L) deficiency in C. elegans leads to small RNA-dependent gene activation

Liontis, T., Verma, K., & Grishok, A. (2023) · BBA Advances · doi:10.1016/j.bbadva.2023.100080 · Cited by 3 · see citing works

Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections

Krulko, I., Ustyanenko, D., & Polischuk, V. P. (2009) · Cytology and Genetics · doi:10.3103/s0095452709010113 · Cited by 3 · see citing works

Detection of Resistance Against Begomovirus Using a SCAR Marker in Melon (Cucumis melo L. cv. Hikapel)

Subiastuti, A. S., Fatmawati, U. E., & Daryono, B. S. (2017) · Springer eBooks · doi:10.1007/978-3-319-60363-6_2 · Cited by 2 · see citing works

Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes

(2021) · doi:10.1101/2021.10.05.463267 · Cited by 2 · see citing works

A Conserved PHD Finger Protein and Endogenous RNAi Modulate Insulin Signaling in Caenorhabditis elegans

Mansisidor, A., Cecere, G., Hoersch, S., Jensen, M. B., Kawli, T., Kennedy, L. M., Chávez, V., Tan, M., Lieb, J. D., & Grishok, A. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002299 · Cited by 1 · see citing works

Diversity and interactions of begomoviruses and their associated DNA-satellites

Sattar, M. N. (2012) · Epsilon Open Archive (Sveriges lantbruksuniversitet biblioteket (Swedish University of Agricultural Sciences)) · Cited by 1 · see citing works

Intergenerational transport of double-stranded RNA limits heritable epigenetic changesPreprint

Shugarts, N., Sathya, A., Yi, A. L., Chan, W. M., Marré, J. A., & Jose, A. M. (2024) · eLife · doi:10.7554/elife.99149.1 · Cited by 1 · see citing works

Understanding the role of RNA-silencing mediated processes in inter-specific hybridisation and origin of Cucumber mosaic virus satellite RNAs

Zahid, K. (2013) · Research Online (University of Wollongong)

An assessment of gene polymorphisms in young South African Indians with coronary artery disease and the effect of atorvastan in vitro.

Phulukdaree, A. (2012) · ResearchSpace (University of KwaZulu-Natal)

Disease in a Changing Ocean: Ecoimmunological Approaches to Coral Reef Ecology

Fuess, L. E. (2018) · UTA ResearchCommons (University of Texas Arlington)

Desvendando mecanismos de controle da longevidade por RNAs móveis

Camara, H. (2021) · doi:10.47749/t/unicamp.2021.1168756

Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changesPreprint

Shugarts, N., Sathya, A., Yi, A. L., Chan, W. M., Marré, J. A., & Jose, A. M. (2024) · eLife · doi:10.7554/elife.99149.2

Mutual regulation of spermatogenesis-specific Argonaute proteins and Insulin/IGF-1 signaling in aging control

Liontis, T., Pannarale, V. T., Mansisidor, A., Pathiranage, S. K., Patel, J. Y., & Grishok, A. (2026) · EMBO Reports · doi:10.1038/s44319-025-00682-4

L'interactome des domaines PDZ de Caenorhabditis elegans

Lenfant, N. (2010) · doi:10.70675/970cf99cz4164z475dz908dzb5f4dd08c402

Rôle des miARN dans la régulation des fonctions plaquettaires

Dréano, E. (2016) · theses.fr (ABES) · doi:10.70675/7f34ffbbz8891z466bzacaez75b277e21002

Two SID-1-dependent genes sensitive to heritable epigenetic changes can also impact reproductionPreprint

Sathya, A., Shugarts, N., Yi, A., & Jose, A. M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.08.730950

The Interactions of Vigilin and the miRISC within Caenorhabditis elegans

Weum, B. (2015) · CU Scholar (University of Colorado Boulder)

JCB: REPORT Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB

Tang, K.-F., Ren, H., Cao, J., Zeng, G.-L., Xie, J., Chen, M., Wang, L., & He, C.-X. (2013)

Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB

Tang, K., Ren, H., Cao, J., Zeng, G.-L., Xie, J., Chen, M., Wang, L., & He, C. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200801169 · Cited by 73 · see citing works

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in <i>C. elegans</i>

Ketting, R. F., Fischer, S. E. J., Bernstein, E., Sijen, T., Hannon, G. J., & Plasterk, R. H. A. (2001) · Genes &amp; Development · doi:10.1101/gad.927801 · Cited by 1,527 · see citing works

A quantitative genome-wide RNAi screen in C. elegans for antifungal innate immunity genes

Zugasti, O., Thakur, N., Belougne, J., Squiban, B., Kurz, C. L., Soulé, J., Omi, S., Tichit, L., Pujol, N., & Ewbank, J. J. (2016) · BMC Biology · doi:10.1186/s12915-016-0256-3 · Cited by 56 · see citing works

Identification of innate immunity genes and pathways using a comparative genomics approach

Alper, S., Laws, R. L., Lackford, B. L., Boyd, W. A., Dunlap, P. E., Freedman, J. H., & Schwartz, D. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802405105 · Cited by 82 · see citing works