“Positive” results increase down the Hierarchy of the Sciences
Open accessAbstract
The hypothesis of a Hierarchy of the Sciences with physical sciences at the top, social sciences at the bottom, and biological sciences in-between is nearly 200 years old. This order is intuitive and reflected in many features of academic life, but whether it reflects the "hardness" of scientific research--i.e., the extent to which research questions and results are determined by data and theories as opposed to non-cognitive factors--is controversial. This study analysed 2434 papers published in all disciplines and that declared to have tested a hypothesis. It was determined how many papers reported a "positive" (full or partial) or "negative" support for the tested hypothesis. If the hierarchy hypothesis is correct, then researchers in "softer" sciences should have fewer constraints to their conscious and unconscious biases, and therefore report more positive outcomes. Results confirmed the predictions at all levels considered: discipline, domain and methodology broadly defined. Controlling for observed differences between pure and applied disciplines, and between papers testing one or several hypotheses, the odds of reporting a positive result were around 5 times higher among papers in the disciplines of Psychology and Psychiatry and Economics and Business compared to Space Science, 2.3 times higher in the domain of social sciences compared to the physical sciences, and 3.4 times higher in studies applying behavioural and social methodologies on people compared to physical and chemical studies on non-biological material. In all comparisons, biological studies had intermediate values. These results suggest that the nature of hypotheses tested and the logical and methodological rigour employed to test them vary systematically across disciplines and fields, depending on the complexity of the subject matter and possibly other factors (e.g., a field's level of historical and/or intellectual development). On the other hand, these results support the scientific status of the social sciences against claims that they are completely subjective, by showing that, when they adopt a scientific approach to discovery, they differ from the natural sciences only by a matter of degree.
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More than 80% of scientific publications in various sciences report positive results.
“which is in line with a study by Fanelli showing that more than 80% of scientific publications in various sciences report positive results (22).”
From Statistical and Methodological Considerations for the Interpretation of Intranasal Oxytocin Studies (2016) · cites this paper as [22]
The Results report that 2045 of 2434 papers (84%) across 20 disciplines gave positive or partial support for a tested hypothesis. But the study included only papers that explicitly tested a hypothesis, and the Discussion notes its focus on English-language scientific journals; it does not establish that more than 80% of scientific publications generally report positive results. (LLM, conf=0.85)
Experimental — accuracy not yet measuredThere is a problem of positive bias in reviews toward or in favor of the testing hypothesis.
“Several authors alert for the problem of a positive bias in reviews toward or in favor of the testing hypothesis (e.g., Fanelli, 2010).”
From Contextual Cognitive-Behavioral Therapies Across the Psychosis Continuum: A Review of Evidence for Schizophrenia, Schizoaffective and Bipolar Disorders (2017) · cites this paper as Fanelli, 2010
The Introduction (page unavailable) says confirmation bias can affect how scientists collect, interpret, and publish data, producing an excess of results supporting tested hypotheses. The Discussion section on non-publication (page unavailable) also describes a bias against negative results. Neither passage establishes that this bias occurs specifically in reviews; the paper discusses research papers and publication decisions. (LLM, conf=0.83)
Experimental — accuracy not yet measuredPotentially problematic practices include selective reporting, selective analysis, and insufficient specification of the conditions necessary or sufficient to obtain the results.
“Potentially problematic practices include selective reporting, selective analysis, and insufficient specification of the conditions necessary or sufficient to obtain the results ( 1223 ).”
From Estimating the reproducibility of psychological science (2015) · cites this paper as [15]
The Discussion sections on non-publication (2C), flexibility in analysis (2A), and manipulation of results (2D) describe keeping negative results unpublished, discretion in analyzing data, and dropping outliers. These support selective reporting and analysis as potentially problematic practices. The copy does not specifically address insufficient specification of the necessary or sufficient conditions for obtaining results. (LLM, conf=0.85)
Experimental — accuracy not yet measuredThe original studies may have inflated effect sizes due to publication, selection, reporting, or other biases.
“An important qualification about this result is the possibility that the original studies have inflated effect sizes due to publication, selection, reporting, or other biases ( 9, 1223 ).”
From Estimating the reproducibility of psychological science (2015) · cites this paper as [15]
The Discussion section on non-publication of negative or nonsignificant results describes publication and selection biases, while the Introduction says confirmation bias can affect data collection, analysis, interpretation, and publication. These passages support the possibility of bias in published studies, but they do not establish that the original studies cited here had inflated effect-size estimates. Our copy provides no page numbers for these passages. (LLM, conf=0.82)
Experimental — accuracy not yet measuredConcerns about reproducibility are widespread across disciplines.
“Concerns about reproducibility are widespread across disciplines ( 921 ).”
From Estimating the reproducibility of psychological science (2015) · cites this paper as [15]
The Introduction (page unavailable) says scientific controversies and cases of 'pathological science' occur across fields. The Discussion (page unavailable) examines cross-disciplinary differences in positive results and notes possible consequences for the reliability of scientific literature. These passages support broad concerns about research reliability, but they do not establish that concerns specifically about reproducibility are widespread across disciplines. (LLM, conf=0.77)
Experimental — accuracy not yet measured
Most papers in behavioral intranasal oxytocin studies report positive findings.
“When reading the literature on behavioral IN-OT studies in humans it is obvious that most papers report positive findings, which is in line with a study by Fanelli showing that more than 80% of scientific publications in various sciences report positive results (22).”
From Statistical and Methodological Considerations for the Interpretation of Intranasal Oxytocin Studies (2016) · cites this paper as [22]
Positive results are much more likely to be published than negative results.
“Positive results are much more likely to be published than negative results 5-7”
From Initial evidence of research quality of registered reports compared with the standard publishing model (2021) · cites this paper as [7]
Positive results are more likely to be published than negative results.
“Positive results -- finding that a treatment is effective or that there is a relationship between two variables -- are more likely to be published than negative results 6-12 .”
From Initial evidence of research quality of registered reports compared with the standard publishing model (2021) · cites this paper as [7]
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Chavalarias, D., Wallach, J. D., Li, A. H. T., & Ioannidis, J. P. A. (2016) · JAMA · doi:10.1001/jama.2016.1952 · Cited by 370 · see citing works
Meta-assessment of bias in science
Fanelli, D., Costas, R., & Ioannidis, J. P. A. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1618569114 · Cited by 364 · see citing works
Self-citationQuestionable research practices in ecology and evolution
Fraser, H., Parker, T., Nakagawa, S., Barnett, A., & Fidler, F. (2018) · PLOS ONE · doi:10.1371/journal.pone.0200303 · Cited by 346 · see citing works
Statistical and Methodological Considerations for the Interpretation of Intranasal Oxytocin Studies
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“When reading the literature on behavioral IN-OT studies in humans it is obvious that most papers report positive findings, which is in line with a study by Fanelli showing that more than 80% of scientific publications in various sciences report positive results (22).”
ResultImplementing Reproducible Research
Stodden, V. (2014) · doi:10.1201/b16868 · Cited by 314 · see citing works
Kostyrka-Allchorne, K., Cooper, N. R., & Simpson, A. (2017) · Developmental Review · doi:10.1016/j.dr.2016.12.002 · Cited by 302 · see citing works
Soderberg, C. K., Errington, T. M., Schiavone, S. R., Bottesini, J., Thorn, F. S., Vazire, S., Esterling, K. M., & Nosek, B. A. (2021) · Nature Human Behaviour · doi:10.1038/s41562-021-01142-4 · Cited by 289 · see citing works
Fanelli, D., Costas, R., & Larivière, V. (2015) · PLOS ONE · doi:10.1371/journal.pone.0127556 · Cited by 268 · see citing works
Self-citationA Short (Personal) Future History of Revolution 2.0
Spellman, B. A. (2015) · Perspectives on Psychological Science · doi:10.1177/1745691615609918 · Cited by 213 · see citing works
Transparency in Ecology and Evolution: Real Problems, Real Solutions
Parker, T. H., Forstmeier, W., Koricheva, J., Fidler, F., Hadfield, J. D., Chee, Y. E., Kelly, C. D., Gurevitch, J., & Nakagawa, S. (2016) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2016.07.002 · Cited by 201 · see citing works
D. Chambers, C., 1 Cardiff University Brain Research Imaging Centre, S. O. P., Feredoes, E., D. Muthukumaraswamy, S., & J. Etchells, P. (2014) · AIMS Neuroscience · doi:10.3934/neuroscience.2014.1.4 · Cited by 213 · see citing works
Dammhahn, M., & Almeling, L. (2012) · Animal Behaviour · doi:10.1016/j.anbehav.2012.08.014 · Cited by 208 · see citing works
The erring brain: Error‐related negativity as an endophenotype for OCD—A review and meta‐analysis
Riesel, A. (2019) · Psychophysiology · doi:10.1111/psyp.13348 · Cited by 170 · see citing works
Teixeira da Silva, J. A., & Dobránszki, J. (2015) · Accountability in Research · doi:10.1080/08989621.2014.899909 · Cited by 158 · see citing works
P-hacking and publication bias interact to distort meta-analytic effect size estimates
Friese, M., & Frankenbach, J. (2020) · Psychological Methods · doi:10.1037/met0000246 · Cited by 122 · see citing works
Coronado-Montoya, S., Levis, A. W., Kwakkenbos, L., Steele, R. J., Turner, E. H., & Thombs, B. D. (2016) · PLOS ONE · doi:10.1371/journal.pone.0153220 · Cited by 107 · see citing works
Commensuration Bias in Peer Review
Lee, C. J. (2015) · Philosophy of Science · doi:10.1086/683652 · Cited by 90 · see citing works
The Past, Present, and Future of Experimental Methods in the Social Sciences
Mize, T. D., & Manago, B. (2022) · Social Science Research · doi:10.1016/j.ssresearch.2022.102799 · Cited by 76 · see citing works
de Winter, J. C., & Dodou, D. (2015) · PeerJ · doi:10.7717/peerj.733 · Cited by 78 · see citing works
Where Are the Self-Correcting Mechanisms in Science?
Vazire, S., & Holcombe, A. O. (2022) · Review of General Psychology · doi:10.1177/10892680211033912 · Cited by 81 · see citing works
Novelty versus Replicability: Virtues and Vices in the Reward System of Science
Romero, F. (2017) · Philosophy of Science · doi:10.1086/694005 · Cited by 61 · see citing works
A Systems-Based Approach to Fostering Robust Science in Industrial-Organizational Psychology
Grand, J. A., Rogelberg, S. G., Allen, T. D., Landis, R. S., Reynolds, D. H., Scott, J. C., Tonidandel, S., & Truxillo, D. M. (2018) · Industrial and Organizational Psychology · doi:10.1017/iop.2017.55 · Cited by 52 · see citing works
Treanor, L., Frank, R. A., Cherpak, L. A., Dehmoobad Sharifabadi, A., Salameh, J.-P., Hallgrimson, Z., Fabiano, N., McGrath, T. A., Kraaijpoel, N., Yao, J., et al. (2020) · European Radiology · doi:10.1007/s00330-019-06568-z · Cited by 38 · see citing works
A retrospective analysis of dissemination biases in the brief alcohol intervention literature.
Tanner-Smith, E. E., & Polanin, J. R. (2015) · Psychology of Addictive Behaviors · doi:10.1037/adb0000014 · Cited by 26 · see citing works
“Whereas some empirical studies have reported that significant and/or positive results are more likely to be published in higher impact factor journals (De Oliveira, Chang, Kendall, Fitzgerald, & McCarthy, 2012; Etter & Stapleton, 2009; Jannot, Agoritsas, Gayet-Ageron, & Perneger, 2013; Timmer, Hilsden, Cole, Hailey, &…”
Research accomplishments that are too good to be true
Ioannidis, J. P. A. (2014) · Intensive Care Medicine · doi:10.1007/s00134-013-3100-z · Cited by 12 · see citing works
Martins, M. J. R. V., Castilho, P., Carvalho, C. B., Pereira, A. T., Santos, V., Gumley, A., & de Macedo, A. F. (2017) · European Psychologist · doi:10.1027/1016-9040/a000283 · Cited by 11 · see citing works
- Authors
- Fanelli, D.
- Affiliations
- University of Edinburgh (GB)
- Corresponding author
- Fanelli, Daniele
- ORCID
- Fanelli, Daniele
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2010-04-07
- Volume
- 5
- Issue
- 4
- Pages
- e10068
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC2850928
- OpenAlex
- W2018443796
- Cited by
- 734
- References
- 84
- Citations by year
- 2026: 24 · 2025: 35 · 2024: 50 · 2023: 47 · 2022: 41 · 2021: 64 · 2020: 74 · 2019: 61 · 2018: 52 · 2017: 74 · 2016: 43 · 2015: 53 · 2014: 47 · 2013: 35 · 2012: 21
- FWCI
- 22.31
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, cc-by)
- Funders
- European Commission (221441)
- Economic and Social Research Council (ES/F028180/1)
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › scientometrics and bibliometrics research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Psychology Research and Bibliometrics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Keywords
- positive results, hypothesis testing, research bias, publication bias, scientific rigor, physical sciences, methodology, scientific status of social sciences
- MeSH terms
- Biological Science Disciplines, Methods, Natural Science Disciplines, Publications, Research, Science, Social Sciences
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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