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Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers
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Many miRNAs of EVs isolated from plasma are dysregulated in AD patients.
“Many miRNAs of EVs isolated from plasma are dysregulated in AD patients [79,85,86,87,88]”
From MicroRNAs in Extracellular Vesicles of Alzheimer’s Disease (2023) · cites this paper as [85]
miR-125-5p, miR-135a-5p and miR-193b were used in AD identification.
“miR-125-5p [85], miR-135a-5p and miR-193b [91] were used in AD identification too.”
From MicroRNAs in Extracellular Vesicles of Alzheimer’s Disease (2023) · cites this paper as [85]
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“338-5p expression is significantly decreased in the plasma exosome of elder people [38].”
BackgroundManzini, V., Cappelletti, P., Orefice, N. S., Brentari, I., Rigby, M. J., Lo Giudice, M., Feligioni, M., Rivabene, R., Crestini, A., Manfredi, F., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-024-04386-z · Cited by 16
Rethinking Alzheimer’s: Novel miRNAs Illuminate a Disease Beyond the Brain
Novotný, J., Čarná, M., Dammer, E., Mao, Z., & Stokin, G. (2025) · doi:10.1101/2025.11.27.690929 · Cited by 1
Metadata
- Authors
- Lugli, G., Cohen, A. M., Bennett, D. A., Shah, R. C., Fields, C. J., Hernandez, A. G., & Smalheiser, N. R.
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2015-10-01
- Volume
- 10
- Issue
- 10
- Pages
- e0139233
- ISSN
- 1932-6203
- PMC
- PMC4591334
- Cited by
- 391
- References
- 6
- Language
- en
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