A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer’s disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls
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The miR-15/107 family accounts for 1.5-2.0% of total miRNA reads in temporal neocortex gray matter of non-demented control brains.
“Analysis of RNA deep sequencing data generated from human brains [12] revealed that miR-15/107 family accounts for 1.5–2.0% of total miRNA reads in the temporal neocortex (Brodmann areas 21/22) gray matter of non-demented control brains.”
From Expression of miR-15/107 Family MicroRNAs in Human Tissues and Cultured Rat Brain Cells (2014) · cites this paper as [12]
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Most mammalian mRNAs are conserved targets of microRNAs
Friedman, R. C., Farh, K. K.-H., Burge, C. B., & Bartel, D. P. (2009) · Genome Research · doi:10.1101/gr.082701.108 · Cited by 8,462 · see citing works
Cogswell, J. P., Ward, J., Taylor, I. A., Waters, M., Shi, Y., Cannon, B., Kelnar, K., Kemppainen, J., Brown, D., Chen, C., et al. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-14103 · Cited by 943 · see citing works
Packer, A. N., Xing, Y., Harper, S. Q., Jones, L., & Davidson, B. L. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2390-08.2008 · Cited by 679 · see citing works
Alterations of the microRNA network cause neurodegenerative disease
Hébert, S. S., & De Strooper, B. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2008.12.003 · Cited by 452 · see citing works
Self-citationMicroRNA regulation of Alzheimer's Amyloid precursor protein expression
Hébert, S. S., Horré, K., Nicolaï, L., Bergmans, B., Papadopoulou, A. S., Delacourte, A., & De Strooper, B. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.11.009 · Cited by 436 · see citing works
Self-citationThe Neuropathology of Older Persons with and Without Dementia from Community versus Clinic Cohorts
Schneider, J. A., Aggarwal, N. T., Barnes, L., Boyle, P., & Bennett, D. A. (2009) · Journal of Alzheimer's Disease · doi:10.3233/jad-2009-1227 · Cited by 372 · see citing works
MicroRNAs and their isomiRs function cooperatively to target common biological pathways
Cloonan, N., Wani, S., Xu, Q., Gu, J., Lea, K., Heater, S., Barbacioru, C., Steptoe, A. L., Martin, H. C., Nourbakhsh, E., et al. (2011) · Genome Biology · doi:10.1186/gb-2011-12-12-r126 · Cited by 345 · see citing works
Peterson, K. J., Dietrich, M. R., & McPeek, M. A. (2009) · BioEssays · doi:10.1002/bies.200900033 · Cited by 252 · see citing works
Long, J. M., Ray, B., & Lahiri, D. K. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.366336 · Cited by 198 · see citing works
Nelson, P. T., Abner, E. L., Schmitt, F. A., Kryscio, R. J., Jicha, G. A., Santacruz, K., Smith, C. D., Patel, E., & Markesbery, W. R. (2009) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3181aacbe9 · Cited by 115 · see citing works
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Research works printed but not linked: 66
- [2]Rapoport SI Nelson PT Biomarkers and evolution in Alzheimer disease Prog Neurobiol 2011 95 510 513 21801803 PMC5878862
- [3]Nelson PT Keller JN RNA in brain disease: No longer just “the messenger in the middle” J Neuropathol Exp Neurol 2007 66 461 468 17549006
- [4]Miranda KC Huynh T Tay Y Ang YS Tam WL Thomson AM Lim B Rigoutsos I A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes Cell 2006 126 1203 1217 16990141
- [6]Nelson PT Wang WX Rajeev BW MicroRNAs (miRNAs) in neurodegenerative diseases Brain Pathol 2008 18 130 138 18226108 PMC2859437
- [7]Hebert SS De Strooper B Molecular biology. miRNAs in neurodegeneration Science 2007 317 1179 1180 17761871
- [9]Hebert SS Nelson PT Studying microRNAs in the brain: Technical lessons learned from the first ten years Exp Neurol 2012 235 397 401 22178329 PMC3637683
- [10]Podolska A Kaczkowski B Litman T Fredholm M Cirera S How the RNA isolation method can affect microRNA microarray results Acta Biochim Pol 2011 58 535 540 22146134
- [11]Sorefan K Pais H Hall AE Kozomara A Griffiths-Jones S Moulton V Dalmay T Reducing sequencing bias of small RNAs Silence 2012 3 4 22647250 PMC3489589
- [12]Nelson PT Wang WX Wilfred BR Tang G Technical variables in high-throughput miRNA expression profiling: Much work remains to be done Biochim Biophys Acta 2008 1779 758 765 18439437 PMC2660892
- [13]Git A Dvinge H Salmon-Divon M Osborne M Kutter C Hadfield J Bertone P Caldas C Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression RNA 2010 16 991 1006 20360395 PMC2856892
- [14]Zhuang F Fuchs RT Sun Z Zheng Y Robb GB Structural bias in T4 RNA ligase-mediated 3′-adapter ligation Nucleic Acids Res 2012 40 e54 22241775 PMC3326334
- [15]Barker WW Luis CA Kashuba A Luis M Harwood DG Loewenstein D Waters C Jimison P Shepherd E Sevush S Graff-Radford N Newland D Todd M Miller B Gold M Heilman K Doty L Goodman I Robinson B Pearl G Dickson D Duara R Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank Alzheimer Dis Assoc Disord 2002 16 203 212 12468894
- [16]Nelson PT Jicha GA Schmitt FA Liu H Davis DG Mendiondo MS Abner EL Markesbery WR Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: Neuritic plaques and neurofibrillary tangles “do count” when staging disease severity J Neuropathol Exp Neurol 2007 66 1136 1146 18090922 PMC3034246
- [19]Hebert SS Horre K Nicolai L Papadopoulou AS Mandemakers W Silahtaroglu AN Kauppinen S Delacourte A De Strooper B Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer’s disease correlates with increased BACE1/beta-secretase expression Proc Natl Acad Sci U S A 2008 105 6415 6420 18434550 PMC2359789
- [20]Nunez-Iglesias J Liu CC Morgan TE Finch CE Zhou XJ Joint genome-wide profiling of miRNA and mRNA expression in Alzheimer’s disease cortex reveals altered miRNA regulation PLoS ONE 2010 5 e8898 20126538 PMC2813862
- [21]Nelson PT Wang WX MiR-107 is reduced in Alzheimer’s disease brain neocortex: Validation study J Alzheimers Dis 2010 21 75 79 20413881 PMC2910235
- [22]Wang WX Rajeev BW Stromberg AJ Ren N Tang G Huang Q Rigoutsos I Nelson PT The expression of microRNA miR-107 decreases early in Alzheimer’s disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1 J Neurosci 2008 28 1213 1223 18234899 PMC2837363
- [23]Lukiw WJ Micro-RNA speciation in fetal, adult and Alzheimer’s disease hippocampus Neuroreport 2007 18 297 300 17314675
- [24]Lukiw WJ Pogue AI Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells J Inorg Biochem 2007 101 1265 1269 17629564 PMC2080079
- [25]Pogue AI Li YY Cui JG Zhao Y Kruck TP Percy ME Tarr MA Lukiw WJ Characterization of an NF-kappaB-regulated, miRNA-146a-mediated down-regulation of complement factor H (CFH) in metal-sulfate-stressed human brain cells J Inorg Biochem 2009 103 1591 1595 19540598
- [26]Sethi P Lukiw WJ Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer’s disease temporal lobe neocortex Neurosci Lett 2009 459 100 104 19406203
- [27]Geekiyanage H Chan C MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid beta, novel targets in sporadic Alzheimer’s disease J Neurosci 2011 31 14820 14830 21994399 PMC3200297
- [29]Zovoilis A Agbemenyah HY Agis-Balboa RC Stilling RM Edbauer D Rao P Farinelli L Delalle I Schmitt A Falkai P Bahari-Javan S Burkhardt S Sananbenesi F Fischer A microRNA-34c is a novel target to treat dementias EMBO J 2011 30 4299 4308 21946562 PMC3199394
- [30]Shioya M Obayashi S Tabunoki H Arima K Saitoh Y Ishida T Satoh J Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neuron navigator-3 Neuropathol Appl Neurobiol 2010 36 320 330 20202123
- [31]Long JM Lahiri DK MicroRNA-101 downregulates Alzheimer’s amyloid-beta precursor protein levels in human cell cultures and is differentially expressed Biochem Biophys Res Commun 2011 404 889 895 21172309 PMC3372402
- [32]Kim J Inoue K Ishii J Vanti WB Voronov SV Murchison E Hannon G Abeliovich A A MicroRNA feedback circuit in midbrain dopamine neurons Science 2007 317 1220 1224 17761882 PMC2782470
- [33]Minones-Moyano E Porta S Escaramis G Rabionet R Iraola S Kagerbauer B Espinosa-Parrilla Y Ferrer I Estivill X Marti E MicroRNA profiling of Parkinson’s disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function Hum Mol Genet 2011 20 3067 3078 21558425
- [34]Santosh PS Arora N Sarma P Pal-Bhadra M Bhadra U Interaction map and selection of microRNA targets in Parkinson’s disease-related genes J Biomed Biotechnol 2009 2009 363145 19911064 PMC2774487
- [35]Marti E Pantano L Banez-Coronel M Llorens F Minones-Moyano E Porta S Sumoy L Ferrer I Estivill X A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing Nucleic Acids Res 2010 38 7219 7235 20591823 PMC2978354
- [37]Jin P Zarnescu DC Ceman S Nakamoto M Mowrey J Jongens TA Nelson DL Moses K Warren ST Bio-chemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway Nat Neurosci 2004 7 113 117 14703574
- [38]Gambardella S Rinaldi F Lepore SM Viola A Loro E Angelini C Vergani L Novelli G Botta A Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients J Transl Med 2010 8 48 20487562 PMC2880982
- [39]Wang WX Wilfred BR Baldwin DA Isett RB Ren N Stromberg A Nelson PT Focus on RNA isolation: Obtaining RNA for microRNA (miRNA) expression profiling analyses of neural tissue Biochim Biophys Acta 2008 1779 749 757 18316046 PMC2650220
- [41]Smith PY Delay C Girard J Papon MA Planel E Sergeant N Buee L Hebert SS MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy Hum Mol Genet 2011 20 4016 4024 21807765
- [42]Smith P Al Hashimi A Girard J Delay C Hebert SS In vivo regulation of amyloid precursor protein neuronal splicing by microRNAs J Neurochem 2011 116 240 247 21062284
- [43]Yu SL Chen HY Yang PC Chen JJ Unique MicroRNA signature and clinical outcome of cancers DNA Cell Biol 2007 26 283 292 17504024
- [44]Jung M Schaefer A Steiner I Kempkensteffen C Stephan C Erbersdobler A Jung K Robust microRNA stability in degraded RNA preparations from human tissue and cell samples Clin Chem 2010 56 998 1006 20378769
- [45]Davoren PA McNeill RE Lowery AJ Kerin MJ Miller N Identification of suitable endogenous control genes for microRNA gene expression analysis in human breast cancer BMC Mol Biol 2008 9 76 18718003 PMC2533012
- [46]Nelson PT Wilfred BR In situ hybridization is a necessary experimental complement to microRNA (miRNA) expression profiling in the human brain Neurosci Lett 2009 466 69 72 19393719 PMC3171000
- [47]Kozomara A Griffiths-Jones S miRBase: Integrating microRNA annotation and deep-sequencing data Nucleic Acids Res 2011 39 D152 D157 21037258 PMC3013655
- [48]Wang WX Huang Q Hu Y Stromberg AJ Nelson PT Patterns of microRNA expression in normal and early Alzheimer’s disease human temporal cortex: White matter versus gray matter Acta Neuropathol 2011 121 193 205 20936480 PMC3073518
- [49]Fernandez-Valverde SL Taft RJ Mattick JS Dynamic isomiR regulation in Drosophila development RNA 2010 16 1881 1888 20805289 PMC2941097
- [51]Zhou H Arcila ML Li Z Lee EJ Henzler C Liu J Rana TM Kosik KS Deep annotation of mouse iso-miR and iso-moR variation Nucleic Acids Res 2012 40 5864 5875 22434881 PMC3401436
- [52]Amariglio N Rechavi G A-to-I RNA editing: A new regulatory mechanism of global gene expression Blood Cells Mol Dis 2007 39 151 155 17555993
- [53]Mehler MF Mattick JS Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease Physiol Rev 2007 87 799 823 17615389
- [54]Mercer TR Dinger ME Mariani J Kosik KS Mehler MF Mattick JS Noncoding RNAs in long-term memory formation Neuroscientist 2008 14 434 445 18997122
- [55]Shao NY Hu HY Yan Z Xu Y Hu H Menzel C Li N Chen W Khaitovich P Comprehensive survey of human brain microRNA by deep sequencing BMC Genomics 2010 11 409 20591156 PMC2996937
- [56]Somel M Guo S Fu N Yan Z Hu HY Xu Y Yuan Y Ning Z Hu Y Menzel C Hu H Lachmann M Zeng R Chen W Khaitovich P MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain Genome Res 2010 20 1207 1218 20647238 PMC2928499
- [57]Hafner M Renwick N Brown M Mihailovic A Holoch D Lin C Pena JT Nusbaum JD Morozov P Ludwig J Ojo T Luo S Schroth G Tuschl T RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries RNA 2011 17 1697 1712 21775473 PMC3162335
- [58]Munafo DB Robb GB Optimization of enzymatic reaction conditions for generating representative pools of cDNA from small RNA RNA 2010 16 2537 2552 20921270 PMC2995414
- [59]Nelson PT Baldwin DA Kloosterman WP Kauppinen S Plasterk RH Mourelatos Z RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain RNA 2006 12 187 191 16373485 PMC1370897
- [60]Lanceta J Prough RA Liang R Wang E MicroRNA group disorganization in aging Exp Gerontol 2010 45 269 278 20034554
- [61]Pandey AK Agarwal P Kaur K Datta M MicroRNAs in diabetes: Tiny players in big disease Cell Physiol Biochem 2009 23 221 232 19471090
- [62]Ibanez-Ventoso C Driscoll M MicroRNAs in C. elegans Aging: Molecular Insurance for Robustness? Curr Genomics 2009 10 144 153 19881908 PMC2705848
- [63]Gascon E Gao FB Cause or effect: Misregulation of microRNA pathways in neurodegeneration Front Neurosci 2012 6 48 22509148 PMC3321503
- [64]Babiarz JE Hsu R Melton C Thomas M Ullian EM Blelloch R A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing RNA 2011 17 1489 1501 21712401 PMC3153973
- [65]Cristino AS Tanaka ED Rubio M Piulachs MD Belles X Deep sequencing of organ- and stage-specific microR-NAs in the evolutionarily basal insect Blattella germanica (L.) (Dictyoptera, Blattellidae) PLoS ONE 2011 6 e19350 21552535 PMC3084283
- [66]Ling KH Brautigan PJ Hahn CN Daish T Rayner JR Cheah PS Raison JM Piltz S Mann JR Mattiske DM Thomas PQ Adelson DL Scott HS Deep sequencing analysis of the developing mouse brain reveals a novel microRNA BMC Genomics 2011 12 176 21466694 PMC3088569
- [67]Shinohara Y Yahagi K Kawano M Nishiyori H Kawazu C Suzuki N Manabe R Hirase H miRNA profiling of bilateral rat hippocampal CA3 by deep sequencing Biochem Biophys Res Commun 2011 409 293 298 21575607
- [68]Finnerty JR Wang WX Hebert SS Wilfred BR Mao G Nelson PT The miR-15/107 group of microRNA genes: Evolutionary biology, cellular functions, and roles in human diseases J Mol Biol 2010 402 491 509 20678503 PMC2978331
- [70]Hebert SS Sergeant N Buee L MicroRNAs and the regulation of tau metabolism Int J Alzheimers Dis 2012 2012 406561 22720189 PMC3374946
- [71]Mellios N Sugihara H Castro J Banerjee A Le C Kumar A Crawford B Strathmann J Tropea D Levine SS Edbauer D Sur M miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity Nat Neurosci 2011 14 1240 1242 21892155 PMC3183341
- [72]Miller BH Zeier Z Xi L Lanz TA Deng S Strathmann J Willoughby D Kenny PJ Elsworth JD Lawrence MS Roth RH Edbauer D Kleiman RJ Wahlestedt C MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function Proc Natl Acad Sci U S A 2012 109 3125 3130 22315408 PMC3286960
- [73]O’Neill LA Boosting the brain’s ability to block inflammation via microRNA-132 Immunity 2009 31 854 855 20064444
- [74]Shaltiel G Hanan M Wolf Y Barbash S Kovalev E Shoham S Soreq H Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetyl-cholinesterase target Brain Struct Funct 2013 218 59 72 22246100 PMC3535403
- [75]Wanet A Tacheny A Arnould T Renard P miR-212/ 132 expression and functions:Within and beyond the neuronal compartment Nucleic Acids Res 2012 40 4742 4753 22362752 PMC3367188
- [76]Chen-Plotkin AS Unger TL Gallagher MD Bill E Kwong LK Volpicelli-Daley L Busch JI Akle S Grossman M Van Deerlin V Trojanowski JQ Lee VM TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways J Neurosci 2012 32 11213 11227 22895706 PMC3446826
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- Authors
- Hébert, S. S., Wang, W.-X., Zhu, Q., & Nelson, P. T.
- Affiliations
- Axe Neurosciences, Centre de recherche du CHU de Québec (CHUL), Québec, QC, Canada
- Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA
- LC Sciences, Houston, TX, USA
- Venue
- Journal of Alzheimer's Disease
- Publisher
- SAGE Publications
- Published
- 2013-04-17
- Volume
- 35
- Issue
- 2
- Pages
- 335-348
- ISSN
- 1875-8908
- 1387-2877
- PMC
- PMC3753694
- Cited by
- 110
- References
- 10
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