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MicroRNA in Alzheimer’s disease: an exploratory study in brain, cerebrospinal fluid and plasma
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miR-146a-5p and miR-132-3p were each reported to be dysregulated in six independent AD studies.
“Among these miRNAs, miR-146a-5p [50,70,73,74,83] and miR-132-3p [48,72,80,81,84] were reported to be dysregulated in six independent AD studies, respectively.”
From MicroRNAs in Extracellular Vesicles of Alzheimer’s Disease (2023) · cites this paper as [81]
miR-132-3p was reported to be up-regulated in AD in one independent study.
“Similar to miR-146a-5p, miR-132-3p was reported to be downregulated in AD in five independent studies [48,72,80,84] but up-regulated in AD in only one independent study [81].”
From MicroRNAs in Extracellular Vesicles of Alzheimer’s Disease (2023) · cites this paper as [81]
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Self-citationGene silencing by microRNAs: contributions of translational repression and mRNA decay
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Mixed brain pathologies account for most dementia cases in community-dwelling older persons
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Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132
Edbauer, D., Neilson, J. R., Foster, K. A., Wang, C.-F., Seeburg, D. P., Batterton, M. N., Tada, T., Dolan, B. M., Sharp, P. A., & Sheng, M. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.005 · Cited by 735
Identifying and validating biomarkers for Alzheimer's disease
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Hippocampal neurons in pre-clinical Alzheimer's disease.
West, M. J., Kawas, C. H., Stewart, W. F., Rudow, G. L., & Troncoso, J. C. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2003.12.005 · Cited by 317 · cited 2×
“AD HP has been reported to contain less neurons relative to astroglial populations than cognitively normal controls (West et al., 2004).”
BackgroundAlzheimer disease: new concepts on its neurobiology and the clinical role imaging will play
Jack, C. R. (2012) · Radiology · doi:10.1148/radiol.12110433 · Cited by 211
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“Previous study suggests that CB shows very little, if any AD-related pathology in end-stage AD, compared to HP (Bobinski et al., 1997; Fukutani et al., 1995; Rossler et al., 2002).”
ResultmiR-132 Mediates the Integration of Newborn Neurons into the Adult Dentate Gyrus
Luikart, B. W., Bensen, A. L., Washburn, E. K., Perederiy, J. V., Su, K. G., Li, Y., Kernie, S. G., Parada, L. F., & Westbrook, G. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019077 · Cited by 160
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Self-citation“End-Stage” Neurofibrillary Tangle Pathology in Preclinical Alzheimer's Disease: Fact or Fiction?
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Effects of aging on circadian patterns of gene expression in the human prefrontal cortex
Chen, C.-Y., Logan, R. W., Ma, T., Lewis, D. A., Tseng, G. C., Sibille, E., & McClung, C. A. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1508249112 · Cited by 277
MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease
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MiRNA Profile in the Substantia Nigra of Parkinson’s Disease and Healthy Subjects
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Antiphospholipid autoantibodies as blood biomarkers for detection of early stage Alzheimer’s disease
McIntyre, J. A., Ramsey, C. J., Gitter, B. D., Saykin, A. J., Wagenknecht, D. R., Hyslop, P. A., & Initiative, F. T. A. D. N. (2015) · Autoimmunity · doi:10.3109/08916934.2015.1008464 · Cited by 22
Metadata
- Authors
- Bekris, L. M., Lutz, F., Montine, T. J., Yu, C. E., Tsuang, D., Peskind, E. R., & Leverenz, J. B.
- Venue
- Biomarkers
- Publisher
- Informa UK Limited
- Published
- 2013-07-03
- Volume
- 18
- Issue
- 5
- Pages
- 455-466
- ISSN
- 1354-750X
- 1366-5804
- PMC
- PMC3967870
- Cited by
- 97
- References
- 12
- Language
- en
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