Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromes

Gene regulation by steroid hormones

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Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs

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Endocrinology of the stress response

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Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*

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The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease

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FK506-binding Proteins 51 and 52 Differentially Regulate Dynein Interaction and Nuclear Translocation of the Glucocorticoid Receptor in Mammalian Cells

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Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells

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Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

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Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor

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SCN Outputs and the Hypothalamic Balance of Life

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Stress, the Stress System and the Role of Glucocorticoids

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Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes

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A Conserved Mechanism for Steroid Receptor Translocation to the Plasma Membrane

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The human glucocorticoid receptor: molecular basis of biologic function

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The glucocorticoid responses are shaped by molecular chaperones

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Cellular processing of the glucocorticoid receptor gene and protein: New mechanisms for generating tissue-specific actions of glucocorticoids

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Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance

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Glucocorticoid sensitivity in health and disease

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Mineralocorticoid and glucocorticoid receptors at the neuronal membrane, regulators of nongenomic corticosteroid signalling

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Intracellular Glucocorticoid Signaling: A Formerly Simple System Turns Stochastic

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Syndromes of Glucocorticoid Resistance

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Generalized Glucocorticoid Resistance: Clinical Aspects, Molecular Mechanisms, and Implications of a Rare Genetic Disorder

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The structural basis of direct glucocorticoid- mediated transrepression

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Circadian endocrine rhythms: the hypothalamic–pituitary–adrenal axis and its actions

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Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominant-negative glucocorticoid receptor mutation.

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Human glucocorticoid receptor isoform β: recent understanding of its potential implications in physiology and pathophysiology

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Glucocorticoids induce mitochondrial gene transcription in HepG2 cells

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Glucocorticoid receptor (GR) β has intrinsic, GRα-independent transcriptional activity

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Molecular Origins for the Dominant Negative Function of Human Glucocorticoid Receptor Beta

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Characterization of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance

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Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor

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Epigenetic programming by stress and glucocorticoids along the human lifespan

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Glucocorticoids cause rapid dissociation of a T‐cell‐receptor‐associated protein complex containing LCK and FYN

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Stress-Related and Circadian Secretion and Target Tissue Actions of Glucocorticoids: Impact on Health

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Insertion of an amino acid in the DNA-binding domain of the glucocorticoid receptor as a result of alternative splicing

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The mitochondrion as a primary site of action of glucocorticoids: the interaction of the glucocorticoid receptor with mitochondrial DNA sequences showing partial similarity to the nuclear glucocorticoid responsive elements

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Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene

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The Human Glucocorticoid Receptor (hGR) β Isoform Suppresses the Transcriptional Activity of hGRα by Interfering with Formation of Active Coactivator Complexes

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Rapid Non-Genomic Feedback Effects of Glucocorticoids on CRF-Induced ACTH Secretion in Rats

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Glucocorticoid receptor structure and function in glucocorticoid-resistant small cell lung carcinoma cells.

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A Novel, C-Terminal Dominant Negative Mutation of the GR Causes Familial Glucocorticoid Resistance through Abnormal Interactions with p160 Steroid Receptor Coactivators

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Expression in hematological malignancies of a glucocorticoid receptor splice variant that augments glucocorticoid receptor-mediated effects in transfected cells

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Nongenomic glucocorticoid receptor action regulates gap junction intercellular communication and neural progenitor cell proliferation

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Adrenal Clocks and the Role of Adrenal Hormones in the Regulation of Circadian Physiology

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Pathologic human GR mutant has a transdominant negative effect on the wild-type GR by inhibiting its translocation into the nucleus: importance of the ligand-binding domain for intracellular GR trafficking

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A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity

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Glucocorticoids and their receptors: Insights into specific roles in mitochondria

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Natural Glucocorticoid Receptor Mutants Causing Generalized Glucocorticoid Resistance: Molecular Genotype, Genetic Transmission, and Clinical Phenotype

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Ultradian corticosterone secretion is maintained in the absence of circadian cues

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Expression and structural analysis of glucocorticoid receptor isoform gamma in human leukaemia cells using an isoform-specific real-time polymerase chain reaction approach

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The glucocorticoid receptor β isoform can mediate transcriptional repression by recruiting histone deacetylases

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Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor

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Primary Generalized Familial and Sporadic Glucocorticoid Resistance (Chrousos Syndrome) and Hypersensitivity

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Import of the glucocorticoid receptor into rat liver mitochondria in vivo and in vitro

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A Novel Point Mutation in Helix 11 of the Ligand-Binding Domain of the Human Glucocorticoid Receptor Gene Causing Generalized Glucocorticoid Resistance

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Extra-adrenal glucocorticoid synthesis: immune regulation and aspects on local organ homeostasis

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Glucocorticoid receptor structure and function in an adrenocorticotropin-secreting small cell lung cancer.

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A Novel Point Mutation in the Amino Terminal Domain of the Human Glucocorticoid Receptor (hGR) Gene Enhancing hGR-Mediated Gene Expression

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Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes

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Functional Characterization of the Natural Human Glucocorticoid Receptor (hGR) Mutants hGRαR477H and hGRαG679S Associated with Generalized Glucocorticoid Resistance

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Human Glucocorticoid Receptor β Regulates Gluconeogenesis and Inflammation in Mouse Liver

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A Novel Point Mutation in Helix 10 of the Human Glucocorticoid Receptor Causes Generalized Glucocorticoid Resistance by Disrupting the Structure of the Ligand-Binding Domain

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Chrousos syndrome: from molecular pathogenesis to therapeutic management

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A Patient with Hypocortisolism and Cushing's Syndrome-Like Manifestations: Cortisol Hyperreactive Syndrome*

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Chrousos syndrome: a seminal report, a phylogenetic enigma and the clinical implications of glucocorticoid signalling changes

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Familial Glucocorticoid Receptor Haploinsufficiency by Non-Sense Mediated mRNA Decay, Adrenal Hyperplasia and Apparent Mineralocorticoid Excess

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Cooperativity and complementarity: Synergies in non-classical and classical glucocorticoid signaling

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Glucocorticoid receptor beta increases migration of human bladder cancer cells

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Strategies for the Characterization of Disorders in Cortisol Sensitivity

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Glucocorticoid Receptor β Acts as a Co-activator of T-Cell Factor 4 and Enhances Glioma Cell Proliferation

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Adrenal Steroid Hormone Secretion

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General Adaptation in Critical Illness: Glucocorticoid Receptor-alpha Master Regulator of Homeostatic Corrections

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Glucocorticoid Resistance: Interference between the Glucocorticoid Receptor and the MAPK Signalling Pathways

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Primary Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes: A 2021 Update

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Role of enhanced glucocorticoid receptor sensitivity in inflammation in PTSD: insights from computational model for circadian-neuroendocrine-immune interactions

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Adrenocortical hyperplasia: A multifaceted disease

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Glucocorticoid signaling and osteoarthritis.

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GR Dimerization and the Impact of GR Dimerization on GR Protein Stability and Half-Life

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Mechanistic inferences on metabolic dysfunction in posttraumatic stress disorder from an integrated model and multiomic analysis: role of glucocorticoid receptor sensitivity

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Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease

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Glucocorticoid Receptor Mutations and Hypersensitivity to Endogenous and Exogenous Glucocorticoids

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Glucocorticoid therapy for acute respiratory distress syndrome: Current concepts

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Transcriptome Responses to Dexamethasone Depending on Dose and Glucocorticoid Receptor Sensitivity in the Liver

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Single-Gene Congenic Strain Reveals the Effect of Zbtb16 on Dexamethasone-Induced Insulin Resistance

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Glucocorticoid Receptor

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Research progress of glucocorticoid resistance in chronic rhinosinusitis with nasal polyps: A review

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Bilateral adrenal incidentalomas and NR3C1 mutations causing glucocorticoid resistance: is there an association?

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Steroids and Sepsis: the Debate Continues

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Is PTSD an Evolutionary Survival Adaptation Initiated by Unrestrained Cytokine Signaling and Maintained by Epigenetic Change?

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General adaptation in critical illness 1: The glucocorticoid signaling system as master rheostat of homeostatic corrections in concerted action with nuclear factor-κB

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Adrenal Cortex Hormones

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Untargeted Plasma Metabolomics Unravels a Metabolic Signature for Tissue Sensitivity to Glucocorticoids in Healthy Subjects: Its Implications in Dietary Planning for a Healthy Lifestyle

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General adaptation in critical illness 2: The glucocorticoid signaling system as a master rheostat of homeostatic corrections in concerted action with mitochondrial and essential micronutrient support

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Prolonged glucocorticoid treatment in ARDS: Pathobiological rationale and pharmacological principles

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The Bidirectional Interaction Between NF‐ κ B and Glucocorticoid Receptor: Underlying Mechanisms of Chronic Stress‐Induced Pathology

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Glucocorticoids and GRα Signaling in Critical Illness: Phase-Specific Homeostatic Corrections Across Systems

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Primary Generalized Glucocorticoid Hypersensitivity Treated with Mifepristone: A Case Report

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Two cases of infantile-onset primary generalized glucocorticoid hypersensitivity and the effect of mifepristone

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Factors Influencing Glucocorticoid Treatment Response: Mechanism-Based Strategies to Overcome Glucocorticoid Resistance and Restore GRα Function

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Glucocorticoid Resistance

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Adrenal Insufficiency: Etiology and Diagnosis

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Beyond Corticoresistance, A Paradoxical Corticosensitivity Induced by Corticosteroid Therapy in Pediatric Acute Lymphoblastic Leukemias

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MEDICINE AND PSYCHOLOGY: MODERN PROBLEMS, NEW TECHNOLOGIES AND WAYS OF DEVELOPING OUTDATED THEORIES

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Endocrine hypertension: discovering the inherited causes

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General Adaptation in Critical Illness: Glucocorticoid Receptor-alpha Master Regulator of Homeostatic Corrections

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Mitochondrial Hormone Receptors - an Emerging Field of Signaling in the Cell’s Powerhouse

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A novel nonsense mutation of the glucocorticoid receptor gene causing glucocorticoid resistance with infertility

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A Case of Glucocorticoid Hypersensitivity Syndrome Associated With Underlying Rubella Virus Infection

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Gonadotrophin-Independent Precocious Puberty; Female and Male

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Glucocorticoid Resistance Syndromes and States

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CORTICORESISTANCE SYNDROME IN CRITICAL ILLNESS: A GIVEN OR A GUIDE TO ACTION?

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Glucocorticoid receptor

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Glucocorticoid resistance syndromes and states

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Implication du récepteur des glucocorticoïdes en physiopathologie humaine

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Research Progress in the Pathogenesis of Severe Asthma

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The Airway Epithelial Barrier in Childhood Asthma: A Central Player in Glucocorticoid Therapy, Resistance, and Severe Asthma

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Recent advances in the molecular mechanisms causing primary generalized glucocorticoid resistance

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Pathophysiology of Glucocorticoid Signaling

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GENETICS IN ENDOCRINOLOGY: Glucocorticoid resistance syndrome

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Generalized Glucocorticoid Resistance: Clinical Aspects, Molecular Mechanisms, and Implications of a Rare Genetic Disorder

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