Integration of evidence from multiple meta-analyses: a primer on umbrella reviews, treatment networks and multiple treatments meta-analyses

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Competing interests: none declared.

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Toward a comprehensive evidence map of overview of systematic review methods: paper 2—risk of bias assessment; synthesis, presentation and summary of the findings; and assessment of the certainty of the evidence

Lunny, C., Brennan, S. E., McDonald, S., & McKenzie, J. E. (2018) · Systematic Reviews · doi:10.1186/s13643-018-0784-8 · Cited by 139 · see citing works

Supported self-management for people with type 2 diabetes: a meta-review of quantitative systematic reviews

Captieux, M., Pearce, G., Parke, H. L., Epiphaniou, E., Wild, S., Taylor, S. J. C., & Pinnock, H. (2018) · BMJ Open · doi:10.1136/bmjopen-2018-024262 · Cited by 132 · see citing works

Efficacy of interventions to reduce coercive treatment in mental health services: umbrella review of randomised evidence

Barbui, C., Purgato, M., Abdulmalik, J., Caldas-de-Almeida, J. M., Eaton, J., Gureje, O., Hanlon, C., Nosè, M., Ostuzzi, G., Saraceno, B., et al. (2021) · The British Journal of Psychiatry · doi:10.1192/bjp.2020.144 · Cited by 148 · see citing works

Risk of bias in overviews of reviews: a scoping review of methodological guidance and four‐item checklist

Ballard, M., & Montgomery, P. (2017) · Research Synthesis Methods · doi:10.1002/jrsm.1229 · Cited by 136 · see citing works

Exercise for Adults with Fibromyalgia: An Umbrella Systematic Review with Synthesis of Best Evidence

Bidonde, J., Busch, A., Bath, B., & Milosavljevic, S. (2014) · Current Rheumatology Reviews · doi:10.2174/1573403x10666140914155304 · Cited by 132 · see citing works

Effectiveness of Technology Interventions in Addressing Social Isolation, Connectedness, and Loneliness in Older Adults: Systematic Umbrella Review

Balki, E., Hayes, N., & Holland, C. (2022) · JMIR Aging · doi:10.2196/40125 · Cited by 132 · see citing works

Pre‐eclampsia and long‐term health outcomes for mother and infant: an umbrella review

Pittara, T., Vyrides, A., Lamnisos, D., & Giannakou, K. (2021) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16683 · Cited by 125 · see citing works

Impact of mental disorders on clinical outcomes of physical diseases: an umbrella review assessing population attributable fraction and generalized impact fraction

Dragioti, E., Radua, J., Solmi, M., Gosling, C. J., Oliver, D., Lascialfari, F., Ahmed, M., Cortese, S., Estradé, A., Arrondo, G., et al. (2023) · World Psychiatry · doi:10.1002/wps.21068 · Cited by 130 · see citing works

Bone mineral density, osteoporosis, and fractures among people with eating disorders: a systematic review and meta-analysis

Solmi, M., Veronese, N., Correll, C. U., Favaro, A., Santonastaso, P., Caregaro, L., Vancampfort, D., Luchini, C., De Hert, M., & Stubbs, B. (2016) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12556 · Cited by 124 · see citing works

Cardiovascular and Renal Outcomes of Renin–Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Meta-Analyses

Catalá-López, F., Macías Saint-Gerons, D., González-Bermejo, D., Rosano, G. M., Davis, B. R., Ridao, M., Zaragoza, A., Montero-Corominas, D., Tobías, A., de la Fuente-Honrubia, C., et al. (2016) · PLOS Medicine · doi:10.1371/journal.pmed.1001971 · Cited by 109 · see citing works

The quality of reporting methods and results in network meta-analyses: An overview of reviews and suggestions for improvement

Hutton, B., Salanti, G., Chaimani, A., Caldwell, D. M., Schmid, C., Thorlund, K., Mills, E., Catalá-López, F., Turner, L., Altman, D. G., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092508 · Cited by 105 · see citing works

What we already know about the effects of exercise in patients with fibromyalgia: An umbrella review

Andrade, A., Dominski, F. H., & Sieczkowska, S. M. (2020) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2020.02.003 · Cited by 95 · see citing works

The prevalence and predictors of comorbid bipolar disorder and obsessive–compulsive disorder: A systematic review and meta-analysis

Amerio, A., Stubbs, B., Odone, A., Tonna, M., Marchesi, C., & Ghaemi, S. N. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.06.005 · Cited by 92 · see citing works

Meta-analytic insights into evolutionary ecology: an introduction and synthesis

Nakagawa, S., & Poulin, R. (2012) · Evolutionary Ecology · doi:10.1007/s10682-012-9593-z · Cited by 77 · see citing works

Impact of organized activities on mental health in children and adolescents: An umbrella review

Boelens, M., Smit, M. S., Raat, H., Bramer, W. M., & Jansen, W. (2022) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2021.101687 · Cited by 65 · see citing works

Effectiveness of multidisciplinary programmes for clinical pain conditions: an umbrella review.

Dragioti, E., Evangelou, E., Larsson, B., & Gerdle, B. (2018) · Journal of Rehabilitation Medicine · doi:10.2340/16501977-2377 · Cited by 53 · see citing works

Topical preparations for the treatment of mild‐to‐moderate acne vulgaris: systematic review and network meta‐analysis*

Stuart, B., Maund, E., Wilcox, C., Sridharan, K., Sivaramakrishnan, G., Regas, C., Newell, D., Soulsby, I., Tang, K. F., Finlay, A. Y., et al. (2021) · British Journal of Dermatology · doi:10.1111/bjd.20080 · Cited by 48 · see citing works

The role of meta-analyses and umbrella reviews in assessing the harms of psychotropic medications: beyond qualitative synthesis.

Solmi, M., Correll, C. U., Carvalho, A. F., & Ioannidis, J. P. A. (2018) · Epidemiology and Psychiatric Sciences · doi:10.1017/s204579601800032x · Cited by 44 · see citing works

Association between adverse childhood experiences and suicidal behavior in schizophrenia spectrum disorders: A systematic review and meta-analysis

Baldini, V., Stefano, R. D., Rindi, L. V., Ahmed, A. O., Koola, M. M., Solmi, M., Papola, D., De Ronchi, D., Barbui, C., & Ostuzzi, G. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115488 · Cited by 46 · see citing works

Diagnostic biomarkers for obsessive-compulsive disorder: A reasonable quest or ignis fatuus?

Fullana, M. A., Abramovitch, A., Via, E., López-Sola, C., Goldberg, X., Reina, N., Fortea, L., Solanes, A., Buckley, M. J., Ramella-Cravaro, V., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.08.008 · Cited by 44 · see citing works

Association between adverse childhood experiences and suicidal behavior in affective disorders: A systematic review and meta-analysis

Baldini, V., Gottardi, C., Di Stefano, R., Rindi, L. V., Pazzocco, G., Varallo, G., Purgato, M., De Ronchi, D., Barbui, C., & Ostuzzi, G. (2025) · European Psychiatry · doi:10.1192/j.eurpsy.2025.2452 · Cited by 41 · see citing works

Meta-analysis of meta-analyses in plant evolutionary ecology

Castellanos, M. C., & Verdú, M. (2012) · Evolutionary Ecology · doi:10.1007/s10682-012-9562-6 · Cited by 19 · see citing works

Can we increase the subjective well-being of the general population? An umbrella review of the evidence

Solanes, A., Albajes-Eizagirre, A., Fullana, M. A., Fortea, L., Fusar-Poli, P., Torrent, C., Solé, B., Bonnín, C. M., Shin, J. I., Vieta, E., et al. (2021) · Revista de Psiquiatría y Salud Mental · doi:10.1016/j.rpsm.2020.08.002 · Cited by 19 · see citing works

Review for "The effect of vitamin D supplementation on mortality and Intensive Care Unit admission of COVID‐19 patients. A systematic review, meta‐analysis and meta‐regression"

(2021) · doi:10.1002/dmrr.3517/v1/review1

Review for "In search of a dose‐response relationship in SSRIs – a systematic review, meta‐analysis and network meta‐analysis"

(2020) · doi:10.1111/acps.13235/v1/review2

Systematic reviews are rarely used to contextualise new results—a systematic review and meta-analysis of meta-research studies

Draborg, E., Andreasen, J., Nørgaard, B., Juhl, C. B., Yost, J., Brunnhuber, K., Robinson, K. A., & Lund, H. (2022) · Systematic Reviews · doi:10.1186/s13643-022-02062-8 · Cited by 17 · see citing works

Locating and Appraising Systematic Reviews

Hunt, D. L., & McKibbon, K. A. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-126-7-199704010-00006 · Cited by 163 · see citing works

Comparison of search strategies in systematic reviews of adverse effects to other systematic reviews

Golder, S., Loke, Y. K., & Zorzela, L. (2014) · Health Information & Libraries Journal · doi:10.1111/hir.12041 · Cited by 57 · see citing works