Cited by 78Memory Processes and InfluencesMemory and Neural MechanismsIdentity, Memory, and Therapy

Emotional Autobiographical Memories in Amnesic Patients with Medial Temporal Lobe Damage

Open access
Buchanan, Tony W., Tranel, Daniel, Adolphs, Ralph·2005·The Journal of Neuroscience

Abstract

The recollection of emotional autobiographical memories has received little attention in patients with memory disorders. Here, we addressed this topic in amnesic patients with damage to the hippocampus (HC group;n= 8) or the hippocampus, amygdala, and surrounding cortices (HC+ group;n= 2). These patients were asked to recollect emotional events from their lives. HC patients produced recollections that were strikingly similar to those of brain-damaged (n= 10) and healthy (n= 25) comparison participants, in terms of both quantity and quality. In contrast, HC+ patients produced a lower proportion of unpleasant memories compared with the other participants. Specifically, the ratings and words used to describe recollections in the HC+ patients were more affectively positive. All groups produced more memories from between 10 and 30 years of age (the so-called autobiographical memory “bump”) compared with other time periods in their lives. These results suggest that structures surrounding the hippocampus, but not the hippocampus itself, may be necessary for the recollection of highly emotional, unpleasant autobiographical memories. The amygdala and surrounding cortices of the medial temporal lobe may be a necessary component in the neural circuitry necessary for vivid recollection of unpleasant emotional events.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1523/jneurosci.4735-04.2005

Cites

46 of 46 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • In amnestic populations with complete impairments in declarative memory, procedural learning can be fully spared.

    “in amnestic populations with complete impairments in declarative memory, both procedural learning (as described above) and affective memories can be fully spared. 54”

    From Domains of cognition and their assessment (2019) · cites this paper as [54]

  • In amnestic populations with complete impairments in declarative memory, affective memories can be fully spared.

    “in amnestic populations with complete impairments in declarative memory, both procedural learning (as described above) and affective memories can be fully spared. 54”

    From Domains of cognition and their assessment (2019) · cites this paper as [54]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Buchanan, T. W., Tranel, D., & Adolphs, R.
Affiliations
  • University of Iowa (US)
  • California Institute of Technology (US)
Venue
The Journal of Neuroscience
Published
2005-03-23
Volume
25
Issue
12
Pages
3151-3160
ISSN
  • 0270-6474 (ISSN-L)
  • 1529-2401
OpenAlex
W2062504721
Cited by
78
References
45
Citations by year
2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 3 · 2019: 5 · 2018: 5 · 2017: 4 · 2016: 1 · 2015: 5 · 2014: 5 · 2013: 3 · 2012: 7
FWCI
3.46
Type
journal article
Language
en
Open access
Locations
  • Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • CaltechAUTHORS (California Institute of Technology) (submittedVersion, cc-by)
Funders
  • U.S. Public Health Service (R01 067681, P01 19632)
  • National Institute on Aging
  • National Institute of Mental Health
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Social Sciences › Psychology › Developmental and Educational Psychology › Identity, Memory, and Therapy
Keywords
amnesia, medial temporal lobe, hippocampus, amygdala, recollection, emotional memory
MeSH terms
Adult, Age Factors, Aged, Amnesia, Analysis of Variance, Brain Mapping, Emotions, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Memory, Middle Aged, Neuropsychological Tests, Temporal Lobe

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review