The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Preconditioning of Low-Frequency Repetitive Transcranial Magnetic Stimulation with Transcranial Direct Current Stimulation: Evidence for Homeostatic Plasticity in the Human Motor Cortex
Open accessAbstract
Recent experimental work in animals has emphasized the importance of homeostatic plasticity as a means of stabilizing the properties of neuronal circuits. Here, we report a phenomenon that indicates a homeostatic pattern of cortical plasticity in healthy human subjects. The experiments combined two techniques that can produce long-term effects on the excitability of corticospinal output neurons: transcranial direct current stimulation (TDCS) and repetitive transcranial magnetic stimulation (rTMS) of the left primary motor cortex. “Facilitatory preconditioning” with anodal TDCS caused a subsequent period of 1 Hz rTMS to reduce corticospinal excitability to below baseline levels for >20 min. Conversely, “inhibitory preconditioning” with cathodal TDCS resulted in 1 Hz rTMS increasing corticospinal excitability for at least 20 min. No changes in excitability occurred when 1 Hz rTMS was preceded by sham TDCS. Thus, changing the initial state of the motor cortex by a period of DC polarization reversed the conditioning effects of 1 Hz rTMS. These preconditioning effects of TDCS suggest the existence of a homeostatic mechanism in the human motor cortex that stabilizes corticospinal excitability within a physiologically useful range.
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Cites
The assessment and analysis of handedness: The Edinburgh inventory
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Self-citationBienenstock, E., Cooper, L., & Munro, P. (1982) · The Journal of Neuroscience · doi:10.1523/jneurosci.02-01-00032.1982 · Cited by 2,896
Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans
Nitsche, M. A., & Paulus, W. (2001) · Neurology · doi:10.1212/wnl.57.10.1899 · Cited by 2,617
Self-citationSynaptic plasticity: taming the beast
Abbott, L. F., & Nelson, S. B. (2000) · Nature Neuroscience · doi:10.1038/81453 · Cited by 2,263 · cited 3×
“This " homeostatic plasticity " enables selective modification of synaptic strength while maintaining total synaptic strength within a physiological range (Abraham and Tate, 1997; Abbott and Nelson, 2000; Turrigiano and Nelson, 2004).”
BackgroundDepression of motor cortex excitability by low-frequency transcranial magnetic stimulation
Chen, R., Classen, J., Gerloff, C., Celnik, P., Wassermann, E. M., Hallett, M., & Cohen, L. G. (1997) · Neurology · doi:10.1212/wnl.48.5.1398 · Cited by 2,128 · cited 9×
“However, the decrease in excitability is seen more prominently and for a longer time if the intensity of the rTMS is above RMT (Chen et al., 1997; Muellbacher et al., 2000) rather than at or below RMT, when the effects are much less consistent (Siebner et al., 1999b; Maeda et al., 2000a; Touge et…”
BackgroundInfluentialTranscranial magnetic stimulation and the human brain
Hallett, M. (2000) · Nature · doi:10.1038/35018000 · Cited by 1,603 · cited 2×
“During 1 Hz rTMS, each magnetic stimulus generates a pulsed magnetic field to induce an electrical current in the underlying brain (Rothwell, 1997; Hallett, 2000 ).”
Synaptic plasticity: LTP and LTD
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Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia
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Early consolidation in human primary motor cortex
Muellbacher, W., Ziemann, U., Wissel, J., Dang, N., Kofler, M., Facchini, S., Boroojerdi, B., Poewe, W., & Hallett, M. (2002) · Nature · doi:10.1038/nature712 · Cited by 803 · cited 1×
“…on cortical excitability has been used to induce a temporary cortical dysfunction in healthy subjects (Kosslyn et al., 1999; Hilgetag et al., 2001; Muellbacher et al., 2002; Knecht et al., 2003) or, presumably by normalizing increased levels of excitability, to induce beneficial effects in…”
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Cited by
Rossi, S., Hallett, M., Rossini, P. M., & Pascual-Leone, A. (2009) · Clinical Neurophysiology · doi:10.1016/j.clinph.2009.08.016 · Cited by 5,367
Transcranial direct current stimulation: State of the art 2008
Nitsche, M. A., Cohen, L. G., Wassermann, E. M., Priori, A., Lang, N., Antal, A., Paulus, W., Hummel, F., Boggio, P. S., Fregni, F., et al. (2008) · Brain Stimulation · doi:10.1016/j.brs.2008.06.004 · Cited by 3,057
Self-citationLefaucheur, J.-P., André-Obadia, N., Antal, A., Ayache, S. S., Baeken, C., Benninger, D. H., Cantello, R. M., Cincotta, M., de Carvalho, M., De Ridder, D., et al. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.05.021 · Cited by 2,119
Self-citationRossi, S., Antal, A., Bestmann, S., Bikson, M., Brewer, C., Brockmöller, J., Carpenter, L. L., Cincotta, M., Chen, R., Daskalakis, J. D., et al. (2021) · Clinical Neurophysiology · doi:10.1016/j.clinph.2020.10.003 · Cited by 1,573
Self-citationBrunoni, A. R., Nitsche, M. A., Bolognini, N., Bikson, M., Wagner, T., Merabet, L., Edwards, D. J., Valero-Cabre, A., Rotenberg, A., Pascual-Leone, A., et al. (2012) · Brain stimulation · doi:10.1016/j.brs.2011.03.002 · Cited by 1,445
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Metadata
- Authors
- Siebner, H. R., Lang, N., Rizzo, V., Nitsche, M. A., Paulus, W., Lemon, R. N., & Rothwell, J. C.
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2004-03-31
- Volume
- 24
- Issue
- 13
- Pages
- 3379-3385
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- OpenAlex
- W2170133769
- Cited by
- 711
- References
- 12
- FWCI
- 17.69
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Siebner, H. R., Lang, N., Rizzo, V., Nitsche, M. A., Paulus, W., Lemon, R. N., & Rothwell, J. C. (2004). Preconditioning of Low-Frequency Repetitive Transcranial Magnetic Stimulation with Transcranial Direct Current Stimulation: Evidence for Homeostatic Plasticity in the Human Motor Cortex. The Journal of Neuroscience. https://doi.org/10.1523/jneurosci.5316-03.2004
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
