Cited by 291Thyroid Disorders and TreatmentsHeart Failure Treatment and ManagementCardiovascular Function and Risk Factors

The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.

MECHANISMS IN ENDOCRINOLOGY: Heart failure and thyroid dysfunction

Biondi, Bernadette·2012·European Journal of Endocrinology

DOI 10.1530/eje-12-0627

Open this paper in CoChat — free account

Abstract

Context: Heart failure (HF) is a major cause of morbidity and mortality in Europe and in the United States. The aim of this review article was to assess the results of the prospective studies that evaluated the risk of HF in patients with overt and subclinical thyroid disease and discuss the mechanism of this dysfunction. Evidence Acquisition: Reports published with the following search terms were searched:, thyroid, hypothyroidism, hyperthyroidism, subclinical hyperthyroidism, subclinical hypothyroidism, levothyroxine, triiodothyronine, antithyroid drugs, radioiodine, deiodinases, clinical symptoms, heart rate, HF, systolic function, diastolic function, systemic vascular resistance, endothelial function, amiodarone and atrial fibrillation. The investigation was restricted to reports published in English. Evidence Synthesis: The outcome of this analysis suggests that patients with untreated overt thyroid dysfunction are at increased risk of HF. Moreover, persistent subclinical thyroid dysfunction is associated with the development of HF in patients with serum TSH <0.1 or >10 mU/l. Conclusions: The timely recognition and effective treatment of cardiac symptoms in patients with thyroid dysfunction is mandatory because the prognosis of HF may be improved with the appropriate treatment of thyroid dysfunction.

Integrity signals

Registry

Crossref · 10.1530/eje-12-0627

Cites

105 of 105 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

2013 ACCF/AHA Guideline for the Management of Heart Failure
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.05.019 · Cited by 12,536
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
Hunt, S. A., Abraham, W. T., Chin, M. H., Feldman, A. M., Francis, G. S., Ganiats, T. G., Jessup, M. L., Konstam, M. A., MANCINI, D. M., Michl, K., et al. (2009) · Circulation · doi:10.1161/circulationaha.109.192065 · Cited by 3,739
The Cardiovascular Health Study: design and rationale.
Fried, L. P., Borhani, N. O., Enright, P., Furberg, C. D., Gardin, J. M., Kronmal, R. A., Kuller, L. H., Manolio, T. A., Mittelmark, M. B., Newman, A., et al. (1991) · Annals of Epidemiology · doi:10.1016/1047-2797(91)90005-w · Cited by 3,652
Trends in Heart Failure Incidence and Survival in a Community-Based Population
Roger, V. L. (2004) · JAMA · doi:10.1001/jama.292.3.344 · Cited by 1,616
2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults
Jessup, M. L., Abraham, W. T., Casey, D. E., Feldman, A. M., Francis, G. S., Ganiats, T. G., Konstam, M. A., MANCINI, D. M., Rahko, P. S., Silver, M. A., et al. (2009) · Circulation · doi:10.1161/circulationaha.109.192064 · Cited by 1,425
The Clinical Significance of Subclinical Thyroid Dysfunction
Biondi, B., & Cooper, D. S. (2008) · Endocrine Reviews · doi:10.1210/er.2006-0043 · Cited by 1,418
Self-citation
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
Hunt, S. A., Abraham, W. T., Chin, M. H., Feldman, A. M., Francis, G. S., Ganiats, T. G., Jessup, M. L., Konstam, M. A., MANCINI, D. M., Michl, K., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.11.013 · Cited by 1,398
Thyroid Disease and the Heart
Klein, I., & Danzi, S. (2007) · Circulation · doi:10.1161/circulationaha.106.678326 · Cited by 1,324
Predicting Mortality Among Patients Hospitalized for Heart Failure
Lee, D. S., Austin, P. C., Rouleau, J. L., Liu, P. P., Naimark, D. M. J., & Tu, J. V. (2003) · JAMA · doi:10.1001/jama.290.19.2581 · Cited by 1,270
Subclinical Hypothyroidism and the Risk of Coronary Heart Disease and Mortality
Rodondi, N., den Elzen, W. P. J., Bauer, D. C., Cappola, A. R., Razvi, S., Walsh, J. P., Åsvold, B. O., Iervasi, G., Imaizumi, M., Collet, T.-H., et al. (2010) · JAMA · doi:10.1001/jama.2010.1361 · Cited by 1,216
Subclinical thyroid disease
Cooper, D. S., & Biondi, B. (2012) · The Lancet · doi:10.1016/s0140-6736(11)60276-6 · Cited by 1,039
Self-citation
Thyroid Status, Cardiovascular Risk, and Mortality in Older Adults
Cappola, A. R., Fried, L. P., Arnold, A. M., Danese, M. D., Kuller, L. H., Burke, G. L., Tracy, R. P., & Ladenson, P. W. (2006) · JAMA · doi:10.1001/jama.295.9.1033 · Cited by 862
Subclinical hyperthyroidism and the risk of coronary heart disease and mortality
Collet, T.-H., Gussekloo, J., Bauer, D. C., den Elzen, W. P. J., Cappola, A. R., Balmer, P., Iervasi, G., Åsvold, B. O., Sgarbi, J. A., Völzke, H., et al. (2012) · Archives of Internal Medicine · doi:10.1001/archinternmed.2012.402 · Cited by 572
Integrin αVβ3 Contains a Cell Surface Receptor Site for Thyroid Hormone that Is Linked to Activation of Mitogen-Activated Protein Kinase and Induction of Angiogenesis
Bergh, J. J., Lin, H., Lansing, L., Mohamed, S. N., Davis, F. B., Mousa, S. A., & Davis, P. J. (2005) · Endocrinology · doi:10.1210/en.2005-0102 · Cited by 563
Subclinical Thyroid Dysfunction and the Risk of Heart Failure Events: An Individual Participant Data Analysis From 6 Prospective Cohorts
Gencer, B., Collet, T.-H., Virgini, V., Bauer, D. C., Gussekloo, J., Cappola, A. R., Nanchen, D., den Elzen, W. P. J., Balmer, P., Luben, R. N., et al. (2012) · Circulation · doi:10.1161/circulationaha.112.096024 · Cited by 517
Subclinical hypothyroidism and the risk of heart failure, other cardiovascular events, and death
Rodondi, N., Newman, A. B., Vittinghoff, E., de Rekeneire, N., Satterfield, S., Harris, T. B., & Bauer, D. C. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.21.2460 · Cited by 503
Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease
Iervasi, G., Pingitore, A., Landi, P., Raciti, M., Ripoli, A., Scarlattini, M., L’Abbate, A., & Donato, L. (2003) · Circulation · doi:10.1161/01.cir.0000048124.64204.3f · Cited by 472
Effects of Thyroid Hormone on the Cardiovascular System
Fazio, S. (2004) · Recent Progress in Hormone Research · doi:10.1210/rp.59.1.31 · Cited by 445
Hypothyroidism as a Risk Factor for Cardiovascular Disease
Biondi, B., & Klein, I. L. (2004) · Endocrine · doi:10.1385/endo:24:1:001 · Cited by 411
Self-citation
Mechanisms of thyroid hormone receptor-specific nuclear and extra nuclear actions
Bassett, J. H. D., Harvey, C. B., & Williams, G. R. (2003) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2003.10.033 · Cited by 392
The Beneficial Effect of l-Thyroxine on Cardiovascular Risk Factors, Endothelial Function, and Quality of Life in Subclinical Hypothyroidism: Randomized, Crossover Trial
Razvi, S., Ingoe, L., Keeka, G., Oates, C., McMillan, C., & Weaver, J. U. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1869 · Cited by 389
Direct evidence for a β1-adrenergic receptor–directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy
Jahns, R., Boivin, V., Hein, L., Triebel, S., Angermann, C. E., Ertl, G., & Lohse, M. J. (2004) · Journal of Clinical Investigation · doi:10.1172/jci20149 · Cited by 384
Mechanisms of nongenomic actions of thyroid hormone
Davis, P. J., Leonard, J. L., & Davis, F. B. (2007) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2007.09.003 · Cited by 364
Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans
Luiza Maia, A. (2005) · Journal of Clinical Investigation · doi:10.1172/jci25083 · Cited by 360
Endogenous Subclinical Hyperthyroidism Affects Quality of Life and Cardiac Morphology and Function in Young and Middle-Aged Patients
Biondi, B. (2000) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.12.4701 · Cited by 356
Self-citation
The Influence of Age on the Relationship between Subclinical Hypothyroidism and Ischemic Heart Disease: A Metaanalysis
Razvi, S., Shakoor, A., Vanderpump, M., Weaver, J. U., & Pearce, S. H. S. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0167 · Cited by 330
Association between increased mortality and mild thyroid dysfunction in cardiac patients
Iervasi, G. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.14.1526 · Cited by 285
Subclinical Thyroid Dysfunction, Cardiac Function, and the Risk of Heart Failure
Rodondi, N., Bauer, D. C., Cappola, A. R., Cornuz, J., Robbins, J., Fried, L. P., Ladenson, P. W., Vittinghoff, E., Gottdiener, J. S., & Newman, A. B. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.07.009 · Cited by 273
Levothyroxine Treatment of Subclinical Hypothyroidism, Fatal and Nonfatal Cardiovascular Events, and Mortality
Razvi, S., Weaver, J. U., Butler, T. J., & Pearce, S. H. S. (2012) · Archives of Internal Medicine · doi:10.1001/archinternmed.2012.1159 · Cited by 266
Thyroid Replacement Therapy and Heart Failure
Gerdes, A. M., & Iervasi, G. (2010) · Circulation · doi:10.1161/circulationaha.109.917922 · Cited by 249
Incidence, clinical characteristics and outcome of congestive heart failure as the initial presentation in patients with primary hyperthyroidism
Siu, C., Yeung, C. Y., Lau, C. P., Kung, A. W. C., & Tse, H.-F. (2006) · Heart · doi:10.1136/hrt.2006.100628 · Cited by 246
Effects of Thyroid Hormone on Cardiac Function - The Relative Importance of Heart Rate, Loading Conditions, and Myocardial Contractility in the Regulation of Cardiac Performance in Human Hyperthyroidism
Biondi, B., Palmieri, E. A., Lombardi, G., & Fazio, S. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.3.8302 · Cited by 245
Self-citation
High Frequency of and Factors Associated with Thyroid Hormone Over-Replacement and Under-Replacement in Men and Women Aged 65 and Over
Somwaru, L. L., Arnold, A. M., Joshi, N., Fried, L. P., & Cappola, A. R. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1696 · Cited by 239
Thyroid Diseases and Cerebrovascular Disease
Squizzato, A., Gerdes, V. E. A., Brandjes, D. P. M., Büller, H. R., & Stam, J. (2005) · Stroke · doi:10.1161/01.str.0000181772.78492.07 · Cited by 236
Cardiovascular involvement in patients with different causes of hyperthyroidism
Biondi, B., & Kahaly, G. J. (2010) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2010.105 · Cited by 230
Self-citation
Thyroid hormone markedly increases the mRNA coding for sarcoplasmic reticulum Ca2+-ATPase in the rat heart.
Rohrer, D. K., & DILLMANN, W. H. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68584-9 · Cited by 228
Abnormal Left Ventricular Function in Hyperthyroidism
Forfar, J. C., Muir, A. L., Sawers, S., & Toft, A. D. (1982) · New England Journal of Medicine · doi:10.1056/nejm198211043071901 · Cited by 226
Subclinical hyperthyroidism: clinical features and treatment options
Biondi, B., Palmieri, E. A., Klain, M., Schlumberger, M., Filetti, S., & Lombardi, G. (2005) · European Journal of Endocrinology · doi:10.1530/eje.1.01809 · Cited by 217
Self-citation
Subclinical Thyroid Dysfunction and the Risk of Heart Failure in Older Persons at High Cardiovascular Risk
Nanchen, D., Gussekloo, J., Westendorp, R. G. J., Stott, D. J., Jukema, J. W., Trompet, S., Ford, I., Welsh, P., Sattar, N., Macfarlane, P. W., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1978 · Cited by 211
Triiodothyronine levels for risk stratification of patients with chronic heart failure
Pingitore, A., Landi, P., Taddei, M. C., Ripoli, A., L’Abbate, A., & Iervasi, G. (2005) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.07.052 · Cited by 192
Reversibility of tachycardia-induced cardiomyopathy after cure of incessant supraventricular tachycardia
Cruz, F. E. S., Cheriex, E. C., Smeets, J. L. R. M., Atié, J., Péres, A. K., Penn, O. C. K. M., Brugada, P., & Wellens, H. J. J. (1990) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(90)90368-y · Cited by 188
Impact of Hyperthyroidism and Its Correction on Vascular Reactivity in Humans
Napoli, R., Biondi, B., Guardasole, V., Matarazzo, M., Pardo, F., Angelini, V., Fazio, S., & Saccà, L. (2001) · Circulation · doi:10.1161/hc5001.100621 · Cited by 187
Self-citation
Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction
Tang, Y.-D., Kuzman, J. A., Said, S., Anderson, B. E., Wang, X., & Gerdes, A. M. (2005) · Circulation · doi:10.1161/circulationaha.105.572883 · Cited by 179
Reversible alterations in myocardial gene expression in a young man with dilated cardiomyopathy and hypothyroidism.
Ladenson, P. W., Sherman, S. I., Baughman, K. L., Ray, P. E., & Feldman, A. M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.12.5251 · Cited by 175
A critical review and meta-analysis of the association between overt hyperthyroidism and mortality
Brandt, F., Green, A., Hegedüs, L., & Brix, T. H. (2011) · European Journal of Endocrinology · doi:10.1530/eje-11-0299 · Cited by 170
Does subclinical hypothyroidism affect cardiac pump performance?
Ripoli, A., Pingitore, A., Favilli, B., Bottoni, A., Turchi, S., Osman, N. F., De Marchi, D., Lombardi, M., L'Abbate, A., & Iervasi, G. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.10.044 · Cited by 157
Amiodarone and thyroid
Eskes, S. A., & Wiersinga, W. M. (2009) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2009.07.001 · Cited by 148
The role of thyroid hormone in the pathophysiology of heart failure: clinical evidence
Galli, E., Pingitore, A., & Iervasi, G. (2010) · Heart Failure Reviews · doi:10.1007/s10741-008-9126-6 · Cited by 132
Thyroid hormone and angiogenesis
Luidens, M. K., Mousa, S. A., Davis, F. B., Lin, H., & Davis, P. J. (2009) · Vascular Pharmacology · doi:10.1016/j.vph.2009.10.007 · Cited by 127
Subclinical Hypothyroidism and Cardiac Function
Biondi, B., Palmieri, E. A., Lombardi, G., & Fazio, S. (2002) · Thyroid · doi:10.1089/105072502760143890 · Cited by 125
Self-citation
Hemodynamic changes in hyperthyroidism-related pulmonary hypertension: a prospective echocardiographic study
Siu, C.-W., Zhang, X.-H., Yung, C., Kung, A. W. C., Lau, C.-P., & Tse, H.-F. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1877 · Cited by 121
Signaling Pathways Responsible for Fetal Gene Induction in the Failing Human Heart
Kinugawa, K., Minobe, W. A., Wood, W. M., Ridgway, E. C., Baxter, J. D., Ribeiro, R. C. J., Tawadrous, M., Lowes, B. D., Long, C. S., & Bristow, M. R. (2001) · Circulation · doi:10.1161/01.cir.103.8.1089 · Cited by 121
Assessment of left ventricular diastolic function by radionuclide ventriculography at rest and exercise in subclinical hypothyroidism, and its response to l-thyroxine therapy
Brenta, G., Mutti, L. A., Schnitman, M., Fretes, O., Perrone, A., & Matute, M. L. (2003) · The American Journal of Cardiology · doi:10.1016/s0002-9149(03)00322-9 · Cited by 118
DITPA (3,5-Diiodothyropropionic Acid), a Thyroid Hormone Analog to Treat Heart Failure: Phase II Trial Veterans Affairs Cooperative Study
Goldman, S., McCarren, M., Morkin, E., Ladenson, P. W., Edson, R., Warren, S., Ohm, J., Thai, H., Churby, L., Barnhill, J., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.834424 · Cited by 117
Thyroid Hormone Therapy for Obesity and Nonthyroidal Illnesses: A Systematic Review
Kaptein, E. M., Beale, E., & Chan, L. S. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0899 · Cited by 110
Cardiovascular Effects of Mild Hypothyroidism
Biondi, B. (2007) · Thyroid · doi:10.1089/thy.2007.0158 · Cited by 106
Self-citation
Hyperthyroidism as a high cardiac output state
deGroot, W. J., & Leonard, J. J. (1970) · American Heart Journal · doi:10.1016/0002-8703(70)90318-2 · Cited by 105
Pulmonary Hypertension and Thyroid Disease
Li, J. H., Safford, R. E., Aduen, J. F., Heckman, M. G., Crook, J. E., & Burger, C. D. (2007) · CHEST Journal · doi:10.1378/chest.07-0366 · Cited by 103
Thyroid Disease and Vascular Function
Owen, P. J. D., Sabit, R., & Lazarus, J. H. (2007) · Thyroid · doi:10.1089/thy.2007.0051 · Cited by 101
Natural history, diagnosis and management of subclinical thyroid dysfunction
Biondi, B. (2012) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2011.12.004 · Cited by 98
Self-citation
Physiological Replacement of T 3 Improves Left Ventricular Function in an Animal Model of Myocardial Infarction-Induced Congestive Heart Failure
Henderson, K. K., Danzi, S. E., Paul, J. T., Leya, G. A., Klein, I. L., & Samarel, A. M. (2009) · Circulation Heart Failure · doi:10.1161/circheartfailure.108.810747 · Cited by 97
Amiodarone-Induced Thyrotoxicosis Is a Predictor of Adverse Cardiovascular Outcome
Yiu, K., Jim, M., Siu, C., Lee, C., Yuen, M. M. A., Mok, M. M. Y., Shea, Y.-F., Fan, K., Tse, H., & Chow, W. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1907 · Cited by 96
Evidence for the Presence of Functional Thyrotropin Receptor in Cardiac Muscle
Drvota, V., Janson, A., Norman, C., Sylvén, C., Häggblad, J., Brönnegård, M., & Marcus, C. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1831 · Cited by 94
Downregulation of Vascular Angiotensin II Type 1 Receptor by Thyroid Hormone
Fukuyama, K., Ichiki, T., Takeda, K., Tokunou, T., Iino, N., Masuda, S., Ishibashi, M., Egashira, K., Shimokawa, H., Hirano, K., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000056524.35294.80 · Cited by 84
Hyperthyroidism and pulmonary hypertension
Marvisi, M., Brianti, M., Marani, G., Borrello, P. D., Bortesi, M., & GUARIGLIA, A. (2002) · Respiratory Medicine · doi:10.1053/rmed.2001.1260 · Cited by 83
Prognostic role of sub-clinical hypothyroidism in chronic heart failure outpatients
Iacoviello, M., Guida, P., Guastamacchia, E., Triggiani, V., Forleo, C., Catanzaro, R., Cicala, M., Basile, M., Sorrentino, S., & Favale, S. (2008) · Current Pharmaceutical Design · doi:10.2174/138161208786264142 · Cited by 82
Thyroid Hormone Regulates Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel (HCN2) mRNA in the Rat Heart
Pachucki, J., Burmeister, L. A., & Larsen, P. R. (1999) · Circulation Research · doi:10.1161/01.res.85.6.498 · Cited by 81
Total Thyroidectomy in Patients with Amiodarone-Induced Thyrotoxicosis and Severe Left Ventricular Systolic Dysfunction
Tomisti, L., Materazzi, G., Bartalena, L., Rossi, G., Marchello, A., Moretti, M., De Napoli, L., Mariotti, R., Miccoli, P., Martino, E., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1797 · Cited by 75
Signaling mechanisms in thyroid hormone-induced cardiac hypertrophy
Ojamaa, K. (2009) · Vascular Pharmacology · doi:10.1016/j.vph.2009.11.008 · Cited by 74
Reversible Pulmonary Hypertension, Tricuspid Regurgitation and Right-sided Heart Failure Associated With Hyperthyroidism
Lozano, H. F., & Sharma, C. N. (2004) · Cardiology in Review · doi:10.1097/01.crd.0000137259.83169.e3 · Cited by 73
Increased risk of pulmonary embolism among patients with hyperthyroidism: a 5‐year follow‐up study
LIN, H. ‐., Yang, L.-Y., & Kang, J. (2010) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2010.03993.x · Cited by 67
Coordinated capillary and myocardial growth in response to thyroxine treatment
Tomanek, R. J., & Busch, T. L. (1998) · The Anatomical Record · doi:10.1002/(sici)1097-0185(199805)251:1 · Cited by 66
Thyroid Hormone-Regulated Target Genes Have Distinct Patterns of Coactivator Recruitment and Histone Acetylation
Liu, Y., Xia, X., Fondell, J. D., & Yen, P. M. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0101 · Cited by 66
Treatment of subclinical hypothyroidism reverses ischemia and prevents myocyte loss and progressive LV dysfunction in hamsters with dilated cardiomyopathy
Khalife, W. I., Tang, Y.-D., Kuzman, J. A., Thomas, T. A., Anderson, B. E., Said, S., Tille, P. M., Schlenker, E. H., & Gerdes, A. M. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00483.2005 · Cited by 66
Influence of hypothyroidism and the reversal of hypothyroidism on hemodynamics and cell size in the adult rat heart
Liu, Z. (1990) · Journal of Molecular and Cellular Cardiology · doi:10.1016/0022-2828(90)90979-c · Cited by 63
Serum thyroid hormone levels may not accurately reflect thyroid tissue levels and cardiac function in mild hypothyroidism
Liu, Y., Redetzke, R. A., Said, S., Pottala, J. V., de Escobar, G. M., & Gerdes, A. M. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01379.2007 · Cited by 58
Cardiomyopathy associated with Graves' disease
Koshiyama, H., Sellittl, D. F., Akamizu, T., Doi, S. Q., Takeuchi, Y., Lnoue, D., Sakaguchl, H., Takemura, G., Sato, Y., Takatsun, Y., et al. (1996) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1996.tb02068.x · Cited by 57
Myocardial contractility and total arterial stiffness in patients with overt hyperthyroidism: acute effects of beta1-adrenergic blockade
Palmieri, E. A., Fazio, S., Palmieri, V., Lombardi, G., & Biondi, B. (2004) · European Journal of Endocrinology · doi:10.1530/eje.0.1500757 · Cited by 57
Self-citation
Thyroid Hormone Abnormalities in Heart Failure: Possibilities for Therapy
Hamilton, M. A., & Stevenson, L. W. (1996) · Thyroid · doi:10.1089/thy.1996.6.527 · Cited by 55
Hyperthyroidism-induced left ventricular diastolic dysfunction: implication in hyperthyroidism-related heart failure
Yue, W., Chong, B.-H., Zhang, X.-H., Liao, S.-Y., Jim, M., Kung, A. W. C., Tse, H., & Siu, C. (2011) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2011.03981.x · Cited by 54
Hyperthyroidism as a Cause of Pulmonary Arterial Hypertension: A Prospective Study
Armigliato, M., Paolini, R., Aggio, S., Zamboni, S., Galasso, M. P., Zonzin, P., & Cella, G. (2006) · Angiology · doi:10.1177/0003319706293131 · Cited by 53
Thyroid Hormone Receptor-β Is Associated with Coronary Angiogenesis during Pathological Cardiac Hypertrophy
Makino, A., Suárez, J., Wang, H., Belke, D. D., Scott, B. T., & DILLMANN, W. H. (2008) · Endocrinology · doi:10.1210/en.2008-0634 · Cited by 51
Severe Reversible Dilated Cardiomyopathy and Hyperthyroidism: Case Report and Review of the Literature
Boccalandro, C., Boccalandro, F., Orlander, P. R., & Wei, C. F. (2003) · Endocrine Practice · doi:10.4158/ep.9.2.140 · Cited by 49
Hospitalizations in Patients With Heart Failure: Who and Why
Setoguchi, S., & Stevenson, L. W. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.08.015 · Cited by 49
Thyroid Hormone Promotes Remodeling of Coronary Resistance Vessels
Savinova, O. V., Liu, Y., Aasen, G. A., Mao, K., Weltman, N. Y., Nedich, B. L., Liang, Q., & Gerdes, A. M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025054 · Cited by 48
Endothelial-mediated coronary flow reserve in patients with mild thyroid hormone deficiency
Biondi, B., Galderisi, M., Pagano, L., Sidiropulos, M., Pulcrano, M., Errico, A. D., Ippolito, S., Rossi, A., DIVITIIS, O. D., & Lombardi, G. (2009) · European Journal of Endocrinology · doi:10.1530/eje-09-0196 · Cited by 48
Self-citation
Developing thyroid disorders is associated with poor prognosis factors in patient with stable chronic heart failure
Silva-Tinoco, R., Castillo‐Martínez, L., Orea‐Tejeda, A., Orozco-Gutíerrez, J. J., Vázquez-Díaz, O., Montaño-Hernández, P., Flores-Rebollar, A., & Reza‐Albarrán, A. (2009) · International Journal of Cardiology · doi:10.1016/j.ijcard.2009.01.012 · Cited by 46
Thyroid Hormone and Cardiac Disease: From Basic Concepts to Clinical Application
Mourouzis, I. S., Forini, F., Pantos, C. I., & Iervasi, G. (2011) · Journal of Thyroid Research · doi:10.4061/2011/958626 · Cited by 44
Reversible Pulmonary Hypertension and Isolated Right-sided Heart Failure Associated with Hyperthyroidism
Ismail, H. M. (2007) · Journal of General Internal Medicine · doi:10.1007/s11606-006-0032-0 · Cited by 42
Thyrotoxic heart disease
Ngo, A. S.-Y., & Tan, D. C. L. (2006) · Resuscitation · doi:10.1016/j.resuscitation.2006.01.009 · Cited by 36
Reversible dilated cardiomyopathy caused by hypothyroidism
Khochtali, I., Hamza, N., Harzallah, O., Hamdi, S., Saad, J., Golli, M., & Mahjoub, S. (2011) · International Archives of Medicine · doi:10.1186/1755-7682-4-20 · Cited by 34
How could we improve the increased cardiovascular mortality in patients with overt and subclinical hyperthyroidism?
Biondi, B. (2012) · European Journal of Endocrinology · doi:10.1530/eje-12-0585 · Cited by 32
Self-citation
Thyrotoxicosis and pulmonary hypertension
Ronald, C. W., Cheng, A. Y., So, W. Y., Hui, D. S. C., Tong, P. C. Y., & Chow, C. C. (2005) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.03.038 · Cited by 24
Early cardiac hypertrophy induced by thyroxine is accompanied by an increase in VEGF-A expression but not by an increase in capillary density
Anjos-Ramos, L., Carneiro‐Ramos, M. S., Diniz, G. P., Martins-Silva, J., & Barreto‐Chaves, M. L. M. (2006) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-005-0140-y · Cited by 23
Regulation of arteriolar density in adult myocardium during low thyroid conditions
Liu, Y., Sherer, B. A., Redetzke, R. A., & Gerdes, A. M. (2009) · Vascular Pharmacology · doi:10.1016/j.vph.2009.10.003 · Cited by 22
Right heart failure and hyperthyroidism: a neglected presentation
Cohen, J., & Schattner, A. (2003) · The American Journal of Medicine · doi:10.1016/s0002-9343(03)00288-2 · Cited by 20
Hyperthyroidism and risk of atrial fibrillation or flutter: A population-based study
Frost, L., Vestergaard, P., & Mosekilde, L. (2004) · ACC Current Journal Review · doi:10.1016/j.accreview.2004.10.013 · Cited by 17
Congestive heart failure in subjects with thyrotoxicosis in a black community
Anakwue, R. C. (2010) · Vascular Health and Risk Management · doi:10.2147/vhrm.s9871 · Cited by 15
Fatal thyrotoxic cardiomyopathy in a young man
Soh, M. C., & CROXSON, M. S. (2008) · BMJ · doi:10.1136/bmj.a531 · Cited by 13
Thyrotoxicosis-induced Congestive Heart Failure in an Urban Hospital
Wilson, B. E., & Newmark, S. R. (1994) · The American Journal of the Medical Sciences · doi:10.1097/00000441-199412000-00006 · Cited by 12
Severe reversible right heart failure in a patient with hyperthyroidism
Syriou, V., Plastiras, S. C., Paterakis, T., Moyssakis, I. E., & Vlachoyiannopoulos, P. G. (2008) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2006.00979.x · Cited by 9
Reversible Severe Tricuspid Regurgitation with Right Heart Failure Associated with Thyrotoxicosis
Park, J., Shong, M., Lee, J., Choi, S. W., Jeong, J., & Seong, I. W. (2006) · Thyroid · doi:10.1089/thy.2006.16.813 · Cited by 9
Detection of Coronary Artery Stenosis by Phasic Changes in Myocardial Blood Volume by Intravenous Myocardial Contrast Echocardiography in Humans
Fukuda, S., Hozumi, T., Muro, T., Watanabe, H., Hyodo, E., Yoshiyama, M., Takeuchi, K., & Yoshikawa, J. (2004) · Journal of Echocardiography · doi:10.2303/jecho.2.1 · Cited by 6
Clinical manifestations in forty cases of myxedema.
Schwimmer, D. B., Vogel, M., & MCGAVACK, T. H. (1947) · PubMed · Cited by 3
Hyperthyroidism and Risk of Atrial Fibrillation or Flutter: A Population-Based Study
Frost, L., Vestergaard, P., & Mosekilde, L. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.15.1675

Research works printed but not linked: 15

2009, Journal of the American College of Cardiology, 54, 173
Biondi, 2002, Journal of Clinical Endocrinology & Metabolism, 87, 968, 10.1210/jc.87.3.968 · DOI · Paper page
2000, Journal of Clinical Endocrinology & Metabolism, 85, 4702
2006, 70, 287
2008, BMJ, 28, 337
2001, NIGERIAN JOURNAL OF MEDICINE, 6, 50
2004, TROPICAL CARDIOLOGY, 118, 24
2010, VASCULAR HEALTH AND RISK MANAGEMENT, 6, 473
Jahns, 2004, Journal of Clinical Investigation, 113, 1419, 10.1172/JCI200420149 · DOI
2007, Journal of Clinical Endocrinology & Metabolism, 2, 1736
2009, BEST PRACTICE AND RESEARCH CLINICAL ENDOCRINOLOGY AND METABOLISM, 6, 735
McCLENDON, 1947, Journal of Clinical Endocrinology & Metabolism, 7, 468
2011, INTERNATIONAL ARCHIVES OF MEDICINE, 21, 4
2011, JOURNAL OF THYROID RESEARCH, 2011, 958626
2009, Circulation: Heart Failure, 3, 243

Sorted by citations

2013 ETA Guideline: Management of Subclinical Hypothyroidism
Pearce, S. H. S., Brabant, G., Duntas, L. H., Monzani, F., Peeters, R. P., Razvi, S., & Wemeau, J.-L. (2013) · European Thyroid Journal · doi:10.1159/000356507 · Cited by 877
Thyroid hormones and cardiovascular disease
Jabbar, A., Pingitore, A., Pearce, S. H. S., Zaman, A., Iervasi, G., & Razvi, S. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.174 · Cited by 729
Thyroid Hormones and Cardiovascular Function and Diseases
Razvi, S., Jabbar, A., Pingitore, A., Danzi, S., Biondi, B., Klein, I., Peeters, R., Zaman, A., & Iervasi, G. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.02.045 · Cited by 515
Self-citation
The 2015 European Thyroid Association Guidelines on Diagnosis and Treatment of Endogenous Subclinical Hyperthyroidism
Biondi, B., Bartalena, L., Cooper, D. S., Hegedüs, L., Laurberg, P., & Kahaly, G. J. (2015) · European Thyroid Journal · doi:10.1159/000438750 · Cited by 323
Self-citation
Hypothyroidism and the Heart
Udovcic, M., Pena, R. H., Patham, B., Tabatabai, L. S., & Kansara, A. (2017) · Methodist DeBakey Cardiovascular Journal · doi:10.14797/mdcj-13-2-55 · Cited by 308

See all 291

Authors: Biondi, B.
Affiliations: Federico II University Hospital (IT)
Corresponding author: Biondi, Bernadette
ORCID: Biondi, Bernadette
Venue: European Journal of Endocrinology
Publisher: Oxford University Press (OUP)
Published: 2012-11
Volume: 167
Issue: 5
Pages: 609-618
ISSN: 0804-4643 (ISSN-L)
1479-683X
DOI: 10.1530/eje-12-0627
OpenAlex: W2071292391
Cited by: 291
References: 105
Citations by year: 2026: 8 · 2025: 15 · 2024: 13 · 2023: 17 · 2022: 19 · 2021: 26 · 2020: 24 · 2019: 26 · 2018: 23 · 2017: 28 · 2016: 24 · 2015: 23 · 2014: 21 · 2013: 17 · 2012: 3
FWCI: 2.83
Type: journal article
Language: en
Open access: closed
Locations: European Journal of Endocrinology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Keywords: heart failure, thyroid dysfunction, subclinical hypothyroidism, subclinical hyperthyroidism, overt hypothyroidism, overt hyperthyroidism, thyroid hormone replacement, levothyroxine, triiodothyronine, antithyroid drugs, radioactive iodine, deiodinases, systolic function, diastolic function, endothelial function, amiodarone, atrial fibrillation, heart rate, systemic vascular resistance
MeSH terms: Amiodarone, Animals, Anti-Arrhythmia Agents, Atrial Fibrillation, Atrial Flutter, Coronary Disease, Heart Failure, Heart Rate, Humans, Hyperthyroidism, Hypothyroidism, Prognosis, Stroke Volume, Thyroid Diseases, Thyroid Hormones, Thyrotropin, Thyroxine, Triiodothyronine, Practice Guidelines as Topic, Disease Progression, Evidence-Based Medicine

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

MECHANISMS IN ENDOCRINOLOGY: Heart failure and thyroid dysfunction

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks