Health-Related Quality of Life in Children and Adolescents Who Have a Diagnosis of Attention-Deficit/Hyperactivity Disorder
Abstract
Objective The aim of treatment for attention-deficit/hyperactivity disorder (ADHD) is to decrease symptoms, enhance functionality, and improve well-being for the child and his or her close contacts. However, the measurement of treatment response is often limited to measuring symptoms using behavior rating scales and checklists completed by teachers and parents. Because so much of the focus has been on symptom reduction, less is known about other possible health problems, which can be measured easily using health-related quality-of-life (HRQL) questionnaires, which are designed to gather information across a range of health domains. The aim of our study was to measure HRQL in a clinic-based sample of children who had a diagnosis of ADHD and consider the impact of 2 clinical factors, symptom severity and comorbidity, on HRQL. Our specific hypotheses were that parent-reported HRQL would be poorer in children with ADHD than in normative US and Australian pediatric samples, in children with increasing severity of ADHD symptoms, and in children who had diagnoses of comorbid psychiatric disorders. Methods Cross-sectional survey was conducted in British Columbia, Canada. The sample included 165 respondents of 259 eligible children (63.7% response rate) who were referred to the ADHD Clinic in British Columbia between November 2001 and October 2002. Children who are seen in this clinic come from all parts of the province and are diverse in terms of socioeconomic status and case mix. AD…
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Decreased QOL among individuals with ADHD is well established.
“Decreased QOL among individuals with ADHD is well established (Klassen et al. 2004; Topolski et al. 2004; Zambrano-Sanchez et al. 2012), with QOL negatively correlated with symptom severity (Klassen et al. 2004; Matza et al. 2004).”
From Participant-Perceived Quality of Life in a Long-Term, Open-Label Trial of Lisdexamfetamine Dimesylate in Adolescents with Attention-Deficit/Hyperactivity Disorder (2014) · cites this paper as Klassen et al. 2004
QOL is negatively correlated with ADHD symptom severity.
“Decreased QOL among individuals with ADHD is well established (Klassen et al. 2004; Topolski et al. 2004; Zambrano-Sanchez et al. 2012), with QOL negatively correlated with symptom severity (Klassen et al. 2004; Matza et al. 2004).”
From Participant-Perceived Quality of Life in a Long-Term, Open-Label Trial of Lisdexamfetamine Dimesylate in Adolescents with Attention-Deficit/Hyperactivity Disorder (2014) · cites this paper as Klassen et al. 2004
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- Authors
- Klassen, A. F., Miller, A., & Fine, S.
- Affiliations
- University of British Columbia (CA)
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2004-11-01
- Volume
- 114
- Issue
- 5
- Pages
- e541-e547
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2096544279
- Cited by
- 565
- References
- 3
- Citations by year
- 2026: 2 · 2025: 11 · 2024: 15 · 2023: 22 · 2022: 18 · 2021: 30 · 2020: 26 · 2019: 24 · 2018: 22 · 2017: 32 · 2016: 34 · 2015: 29 · 2014: 36 · 2013: 25 · 2012: 29
- FWCI
- 10.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- attention deficit hyperactivity disorder, health-related quality of life, comorbidities, symptom severity, learning disabilities, oppositional defiant disorder, conduct disorder, parent-reported quality of life, Child Health Questionnaire, psychosocial functioning, self-esteem, mental health, physical function, children and adolescents, treatment response assessment, psychometric validation, cross-cultural adaptation
- MeSH terms
- Adolescent, Adolescent Behavior, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Child, Child Behavior Disorders, Female, Health Status, Humans, Male, Mental Health, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Socioeconomic Factors, Comorbidity
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