The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Immunomodulatory and antimicrobial effects of vitamin C
Open accessAbstract
Humans have lost their vitamin C-synthesizing capacities during evolution. Therefore, the uptake of this essential compound from external sources is mandatory in order to prevent vitamin C-deficient conditions resulting in severe morbidities such as scurvy. The potent antioxidant, immunomodulatory, and antiinfectious effects of vitamin C are known since the 1930s. We here (i) review the impact of vitamin C on innate and adaptive immune functions, (ii) provide an overview of its antimicrobial, antibacterial, antiviral, antiparasitic, and antifungal properties, and finally, (iii) discuss vitamin C as an adjunct treatment option for the combat of human infections by bacteria, particularly by emerging multidrug-resistant species.
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Citations
Cites
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Cited by
Alberts, A., Moldoveanu, E.-T., Niculescu, A.-G., & Grumezescu, A. M. (2025) · Molecules · doi:10.3390/molecules30030748 · Cited by 161
Trends in Vitamin C consumption in the United States: 1999-2018
Brauchla, M., Dekker, M. J., & Rehm, C. D. (2021) · Nutrients · doi:10.3390/nu13020420 · Cited by 35
Impact of Diets on Response to Immune Checkpoint Inhibitors (ICIs) Therapy against Tumors
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Metadata
- Authors
- Mousavi, S., Bereswill, S., & Heimesaat, M. M.
- Venue
- European Journal of Microbiology and Immunology
- Publisher
- Akademiai Kiado Zrt.
- Published
- 2019-09
- Volume
- 9
- Issue
- 3
- Pages
- 73-79
- ISSN
- 2062-509X (ISSN-L)
- 2062-8633
- OpenAlex
- W2968212857
- Cited by
- 266
- References
- 12
- FWCI
- 21.94
- Type
- journal article
- Language
- en
- Open access
- diamond
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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