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Oxidative stress and ROS metabolism via down-regulation of sirtuin 3 expression in Cmah-null mice affect hearing loss

Kwon, Deug-Nam, Park, Woo-Jin, Choi, Yun-Jung, Gurunathan, Sangiliyandi, Kim, Jin-Hoi·2015·Aging

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Crossref · 10.18632/aging.100800

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Research works printed but not linked: 41

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  3. Suzuki, 1998, The molecular basis for the absence of N-glycolylneuraminic acid in humans, J Biol Chem, 27, 15866
  4. Takahata, 2001, Alu-mediated inactivation of the human CMP- N-acetylneuraminic acid hydroxylase gene, Proc Natl Acad Sci U S A, 9, 11399
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  6. Kim, 2014, Gene expression and pathway analysis of effects of the CMAH deactivation on mouse lung, kidney and heart, PLoS One, 9, e107559, 10.1371/journal.pone.0107559 · DOI
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  8. Wang, 2012, Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse Cochlea, Antioxid Redox Signal, 1, 263
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  11. Henderson, 2012, Expression pattern of oxidative stress and antioxidant defense-related genes in the aging Fischer 344/NHsd rat cochlea, Neurobiol Aging, 3, e1841
  12. Kahn, 2011, Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production, Proc Natl Acad Sci U S A, 10, 14608
  13. Guarente, 2004, The Sir2 family of protein deacetylases, Annu Rev Biochem, 7, 417
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  15. Guarente, 2010, Aging and disease: connections to sirtuins, Aging Cell, 9, 285, 10.1111/j.1474-9726.2010.00548.x · DOI
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  17. Haigis, 2011, SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization, Cancer Cell, 1, 416
  18. Finkel, 2008, A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis, Proc Natl Acad Sci U S A, 10, 14447
  19. Prolla, 2010, Mitochondrial oxidative damage and apoptosis in age-related hearing loss, Mech Ageing Dev, 13, 480
  20. Gupta, 2009, Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice, J Clin Invest, 11, 2758
  21. Denu, 2011, Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction, Mol Cell, 4, 139
  22. Prolla, 2010, Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction, Cell, 14, 802
  23. Martin, 2010, A human-specific deletion in mouse Cmah increases disease severity in the mdx model of Duchenne muscular dystrophy, Sci Transl Med, 2, 42ra54
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  25. Ohlemiller, 2010, Age-related loss of spiral ganglion neurons, Hear Res, 26, 93
  26. Steinman, 1998, Changes in cochlear antioxidant enzyme activity after sound conditioning and noise exposure in the chinchilla, Hear Res, 11, 31
  27. Salvi, 1999, Age-related cochlear hair cell loss is enhanced in mice lacking copper/zinc superoxide dismutase, Neurobiol Aging, 2, 1
  28. Sacchetti, 2004, Paraoxonase and superoxide dismutase gene polymorphisms and noise-induced hearing loss, Clin Chem, 5, 2012
  29. Sha, 2007, Oxidative imbalance in the aging inner ear, Neurobiol Aging, 2, 1605
  30. Monga, 2007, WNT/beta-catenin signaling in liver health and disease, Hepatology, 4, 1298
  31. Monga, 2011, Role of Wnt/beta-catenin signaling in liver metabolism and cancer, Int J Biochem Cell Biol, 4, 1021, 10.1016/j.biocel.2009.09.001 · DOI
  32. Monga, 2010, Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis, Am J Pathol, 17, 744
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  36. Chang, 2010, Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis, PLoS One, 5, e11707, 10.1371/journal.pone.0011707 · DOI · Paper page
  37. Hakkola, 2012, Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism, PLoS One, 7, e49863, 10.1371/journal.pone.0049863 · DOI
  38. Bellizzi, 2012, SIRT3 gene expression: a link between inherited mitochondrial DNA variants and oxidative stress, Gene, 49, 323
  39. Someya, 2013, Maintaining good hearing: calorie restriction, Sirt3, and glutathione, Exp Gerontol, 4, 1091
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Metadata

Authors
Kwon, D.-N., Park, W.-J., Choi, Y.-J., Gurunathan, S., & Kim, J.-H.
Affiliations
Department of Animal Biotechnology, Konkuk University, Seoul 143-701, Republic of Korea
Venue
Aging
Published
2015-08-29
Volume
7
Issue
8
Pages
579-594
ISSN
1945-4589
Cited by
45
References
8
Language
en

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