PreprintCited by 9Privacy-Preserving Technologies in DataArtificial Intelligence in Healthcare and EducationDomain Adaptation and Few-Shot Learning

Federated Learning for Multi-Center Imaging Diagnostics: A Study in Cardiovascular Disease

Open access
Linardos, Akis, Kushibar, Kaisar, Walsh, Sean, Gkontra, Polyxeni, Lekadir, Karim·2021·Research Square

Abstract

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center datasets, and although some results have shown promise, their generalizability to other institutions remains questionable as the data heterogeneity between institutions is not taken into account. By allowing models to be trained in a distributed manner that preserves patients’ privacy, federated learning promises to alleviate these issues, by enabling diligent multi-center studies. We present the first federated learning study on the modality of cardiovascular magnetic resonance (CMR) and use four centers derived from subsets of the M&M and ACDC datasets, focusing on the diagnosis of hypertrophic cardiomyopathy (HCM). We adapt a 3D-CNN network pretrained on action recognition and explore two different ways of incorporating shape prior information to the model, and four different data augmentation setups , systematically analyzing their impact on the different collaborative learning choices. We show that despite the small size of data (180 subjects derived from four centers), the privacy preserving federated learning achieves promising results that are competitive with traditional centralized learning. We further find that federatively trained models exhibit increased robustness and are more sensitive to domain shift effects.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.21203/rs.3.rs-688924/v1

Cites

61 of 61 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • FL has developed a system that makes it possible for doctors to use data from multiple medical institutions without sharing patient data across them.

    “FL has developed a system that makes it possible for doctors to use data from multiple medical institutions without sharing patient data across them [62].”
  • Given the fact that there can be no comprehensive information distribution among institutions, FL can be trained using non-IID data.

    “Given the fact that there can be no comprehensive information distribution among institutions [56, 62], FL can be trained using non-IID data.”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

2 of the 63 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

  1. Singh, S. P. et al. 3d deep learning on medical images: a review. Sensors 20, 5097 (2020).

Cited by

Sorted by citations

Authors
Linardos, A., Kushibar, K., Walsh, S., Gkontra, P., & Lekadir, K.
Affiliations
  • Universitat de Barcelona (ES)
  • Radiomics
Corresponding author
Linardos, Akis
Venue
Research Square
Published
2021-07-09
OpenAlex
W3179176383
Cited by
9
References
63
Citations by year
2026: 1 · 2025: 1 · 2023: 1 · 2022: 6
Type
posted content
Language
en
Open access
Locations
  • Research Square (acceptedVersion, cc-by)
  • arXiv (Cornell University) (submittedVersion)
  • arXiv (Cornell University)
Funders
European Commission (HORIZON2020, 952103)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Privacy-Preserving Technologies in Data
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Computer Science › Artificial Intelligence › Domain Adaptation and Few-Shot Learning
Keywords
federated learning, cardiovascular magnetic resonance, hypertrophic cardiomyopathy, data heterogeneity, privacy-preserving machine learning, 3D convolutional neural networks, data augmentation, domain shift, model generalization, ACDC dataset

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review