The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
The importance of norepinephrine in depression
Open accessAbstract
Depression is one of the most common psychological diseases with significant potential morbidity and mortality. Although the underlying pathophysiology of depression has not been clearly defined, preclinical and clinical evidence suggest disturbances in serotonin (5-HT), norepinephrine (NE), and dopamine (DA) neurotransmission in the central nervous system. Virtually all currently available antidepressants act on one or more of the following mechanisms: inhibition of reuptake of 5-HT or NE (and DA), antagonism of inhibitory presynaptic 5-HT or NE receptors, or inhibition of monoamine oxidase. All of these mechanisms result in an enhanced neurotransmission of 5-HT and/or NE. Evidence for the involvement of NE in depression is abundant, and recent studies on neuronal pathways and symptoms highlight the specific role of NE in this disorder. NE plays a determinant role in executive functioning regulating cognition, motivation, and intellect, which are fundamental in social relationships. Social dysfunction is possibly one of the most important factors affecting the quality of life in depressed patients.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The pathophysiology of depression is complex and includes social environmental stress factors; genetic and biological processes, such as the overdrive of the HPA axis, inflammation (31), and disturbances in monamine neurotransmission as described above (91).”
From Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders (2018) · cites this paper as [91]
In the citing paper
“Several lines of evidence suggest that NE is a neurotransmitter of major importance in the pathophysiology and treatment of depressive disorders (91).”
From Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders (2018) · cites this paper as [91]
In the citing paper
“Thus, experimental depletion of NE in the brain led to a return of depressive symptoms after successful treatment with NE antidepressant drugs (91).”
From Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders (2018) · cites this paper as [91]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
From inflammation to sickness and depression: when the immune system subjugates the brain
Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395
A Meta-Analysis of Cytokines in Major Depression
Dowlati, Y., Herrmann, N., Swardfager, W., Liu, H., Sham, L., Reim, E. K., & Lanctôt, K. L. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.033 · Cited by 4,729
The molecular neurobiology of depression
Krishnan, V., & Nestler, E. J. (2008) · Nature · doi:10.1038/nature07455 · Cited by 2,889
Belmaker, R. H., & Agam, G. (2008) · New England Journal of Medicine · doi:10.1056/nejmra073096 · Cited by 2,166
Hippocampal volume and depression: a meta-analysis of MRI studies
Videbech, P., & Ravnkilde, B. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.11.1957 · Cited by 1,590
The role of dopamine in the pathophysiology of depression
Dunlop, B. W., & Nemeroff, C. B. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.3.327 · Cited by 1,244
Sen, S., Duman, R., & Sanacora, G. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.05.005 · Cited by 1,232
(2008) · Cited by 889
Ruhé, H. G., Mason, N. S., & Schene, A. H. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001949 · Cited by 861
Eyding, D., Lelgemann, M., Grouven, U., Härter, M. C., Kromp, M., Kaiser, T., Kerekeş, M., Gerken, M., & Wieseler, B. (2010) · BMJ · doi:10.1136/bmj.c4737 · Cited by 600
Cited by
Sorted by citations
Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders
Breit, S., Kupferberg, A., Rogler, G., & Hasler, G. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00044 · Cited by 1,189
“Thus, experimental depletion of NE in the brain led to a return of depressive symptoms after successful treatment with NE antidepressant drugs (91).”
BackgroundA genetically encoded fluorescent sensor for rapid and specific in vivo detection of norepinephrine
Feng, J., Zhang, C., Lischinsky, J. E., Jing, M., Zhou, J., Wang, H., Zhang, Y., Dong, A., Wu, Z., Wu, H., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.02.037 · Cited by 545
McGuinness, A. J., Davis, J. A., Dawson, S. L., Loughman, A., Collier, F., O’Hely, M., Simpson, C. A., Green, J., Marx, W., Hair, C., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01456-3 · Cited by 502
Behl, T., Kaur, D., Sehgal, A., Singh, S., Sharma, N., Zengin, G., Andronie-Cioară, F. L., Toma, M. M., BUNGAU, S. G., & Bumbu, A. G. (2021) · Molecules · doi:10.3390/molecules26123724 · Cited by 340
DSM-5 Criteria and Depression Severity: Implications for Clinical Practice
Tolentino, J. C., & Schmidt, S. L. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00450 · Cited by 311
Mørk, A., Pehrson, A., Brennum, L. T., Nielsen, S. M., Zhong, H., Lassen, A. B., Miller, S., Westrich, L., Boyle, N. J., Sánchez, C., et al. (2012) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.111.189068 · Cited by 271
A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer’s disease agents: A review
Manzoor, S., & Hoda, N. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.112787 · Cited by 267
Uncertainty, epistemics and active inference
Parr, T., & Friston, K. J. (2017) · Journal of The Royal Society Interface · doi:10.1098/rsif.2017.0376 · Cited by 252
Monoamine oxidase inhibitors: Promising therapeutic agents for Alzheimer’s disease (Review)
Cai, Z. (2014) · Molecular Medicine Reports · doi:10.3892/mmr.2014.2040 · Cited by 216
Neuropathologic Correlates of Psychiatric Symptoms in Alzheimer’s Disease
Ehrenberg, A. J., Suemoto, C. K., Resende, E. D. P. F., Petersen, C., Leite, R. E. P., Rodriguez, R. D., Ferretti‐Rebustini, R. E. D. L., You, M. Y., Oh, J. Y., Nitríni, R., et al. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180688 · Cited by 233
Nimgampalle, M., Chakravarthy, H., Sharma, S., Shree, S., Bhat, A. R., Pradeepkiran, J. A., & Devanathan, V. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101994 · Cited by 207
Peripheral Markers of Depression
Nobis, A., Zalewski, D., & Waszkiewicz, N. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9123793 · Cited by 197
Antidepressant Medications and Weight Change: A Narrative Review
Gill, H., Gill, B., El‐Halabi, S., Chen-Li, D. C. J., Lipsitz, O., Rosenblat, J. D., Rheenen, T. E. V., Rodrigues, N. B., Mansur, R. B., Majeed, A., et al. (2020) · Obesity · doi:10.1002/oby.22969 · Cited by 209
Dietary fiber and its associations with depression and inflammation
Swann, O. G., Kilpatrick, M., Breslin, M., & Oddy, W. H. (2020) · Nutrition Reviews · doi:10.1093/nutrit/nuz072 · Cited by 185
Thase, M. E., Youakim, J. M., Skuban, A., Hobart, M., Augustine, C., Zhang, P., McQuade, R. D., Carson, W. H., Nyilas, M., Sanchez, R., et al. (2015) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.14m09688 · Cited by 182
Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system
Xiao, T., Ackerman, C. M., Carroll, E. C., Jia, S., Hoagland, A., Chan, J., Thai, B., Liu, C. S., Isacoff, E. Y., & Chang, C. J. (2018) · Nature Chemical Biology · doi:10.1038/s41589-018-0062-z · Cited by 168
Egorov, A. I., Griffin, S. M., Converse, R. R., Styles, J. N., Sams, E. A., Wilson, A., Jackson, L. E., & Wade, T. J. (2017) · Environmental Research · doi:10.1016/j.envres.2017.07.009 · Cited by 173
Neuromicrobiology, an emerging neurometabolic facet of the gut microbiome?
Miri, S., Yeo, J., Abubaker, S., & Hammami, R. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1098412 · Cited by 176
Wang, S., Leri, F., & Rizvi, S. J. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110289 · Cited by 171
Major Depression: One Brain, One Disease, One Set of Intertwined Processes
Filatova, E. V., Shadrina, M. I., & Slominsky, P. A. (2021) · Cells · doi:10.3390/cells10061283 · Cited by 186
Sequeira‐Cordero, A., Salas-Bastos, A., Fornaguera, J., & Brenes, J. C. (2019) · Scientific Reports · doi:10.1038/s41598-019-53624-1 · Cited by 151
Role of the intestinal microbiome, intestinal barrier and psychobiotics in depression
Trzeciak, P., & Herbet, M. (2021) · Nutrients · doi:10.3390/nu13030927 · Cited by 139
Antidepressant Drugs Effects on Blood Pressure
Calvi, A., Fischetti, I., Verzicco, I., Murri, M. B., Zanetidou, S., Volpi, R., Coghi, P., Tedeschi, S., Amore, M., & Cabassi, A. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.704281 · Cited by 153
Cognitive and psychological issues in postural tachycardia syndrome
Raj, V., Opie, M., & Arnold, A. C. (2018) · Autonomic Neuroscience · doi:10.1016/j.autneu.2018.03.004 · Cited by 125
Early Life Stress, Depression And Parkinson’s Disease: A New Approach
Dallé, E., & Mabandla, M. V. (2018) · Molecular Brain · doi:10.1186/s13041-018-0356-9 · Cited by 131
A Review of Neurotransmitters Sensing Methods for Neuro-Engineering Research
Niyonambaza, S. D., Kumar, P., Xing, P., Mathault, J., Koninck, P. D., Boisselier, É., Boukadoum, M., & Miled, A. (2019) · Applied Sciences · doi:10.3390/app9214719 · Cited by 125
Rădulescu, I. D., Drăgoi, A. M., Trifu, S. C., & Cristea, M. B. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.10565 · Cited by 127
Depression: Biological markers and treatment
Erjavec, G. N., Šagud, M., Perković, M. N., Štrac, D. Š., Konjevod, M., Tudor, L., Uzun, S., & Pivac, N. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110139 · Cited by 127
Krolick, K. N., Zhu, Q., & Shi, H. (2018) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2018.07.008 · Cited by 126
Baranwal, A., & Chandra, P. (2018) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2018.09.002 · Cited by 115
Islam, Z., Hu, H., Akter, S., Kuwahara, K., Kochi, T., Eguchi, M., Kurotani, K., Nanri, A., Kabe, I., & Mizoue, T. (2019) · SLEEP · doi:10.1093/sleep/zsz204 · Cited by 116
Biomarkers for major depressive and bipolar disorders using metabolomics: A systematic review
MacDonald, K., Krishnan, A., Cervenka, E., Hu, G., Guadagno, E., & Trakadis, Y. J. (2018) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32680 · Cited by 108
Monoamine oxidases in age-associated diseases: New perspectives for old enzymes
Santin, Y., Resta, J., Parini, A., & Mialet‐Perez, J. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101256 · Cited by 110
Duan, J., Huang, Y., Tan, X., Chai, T., Wu, J., Zhang, H., Li, Y., Hu, X., Zheng, P., Ji, P., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01428-1 · Cited by 101
Brand, S., Moller, M., & Harvey, B. (2015) · Current Neuropharmacology · doi:10.2174/1570159x13666150307004545 · Cited by 95
Kim, O. Y., & Song, J. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122356 · Cited by 96
Mariani, N., Cattane, N., Pariante, C. M., & Cattaneo, A. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01469-6 · Cited by 96
Major depressive disorder: mechanism-based prescribing for personalized medicine
Lapolla, T., Saltiel, P. F., & Silvershein, D. I. (2015) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s73261 · Cited by 92
Neuron-astrocyte coupling in lateral habenula mediates depressive-like behaviors
Xin, Q., Wang, J., Zheng, J., Tan, Y. J., Jia, X., Ni, Z., Xu, Z., Feng, J., Wu, Z., Li, Y., et al. (2025) · Cell · doi:10.1016/j.cell.2025.04.010 · Cited by 96
Farahani, M. S., Bahramsoltani, R., Farzaei, M. H., Abdollahi, M. R., & Rahimi, R. (2015) · Reviews in the Neurosciences · doi:10.1515/revneuro-2014-0058 · Cited by 85
Minichino, A., Bersani, F. S., Trabucchi, G., Albano, G., Primavera, M., Delle Chiaie, R., & Biondi, M. (2014) · Rivista di Psichiatria · doi:10.1708/1551.16907 · Cited by 80
Chen, Y.-H., Xue, F., Yu, S.-F., Li, X.-S., Liu, L., Jia, Y., Yan, W., Tan, Q.-R., Wang, H., & Peng, Z. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.12.143 · Cited by 83
Mandal, P. K., Gaur, S., Roy, R. G., Samkaria, A., Ingole, R., & Goel, A. (2022) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.2c00420 · Cited by 78
Inflammation in the pathogenesis of depression: a disorder of neuroimmune origin
Corrigan, M., O’Rourke, A. M., Moran, B., Fletcher, J. M., & Harkin, A. (2023) · Neuronal Signaling · doi:10.1042/ns20220054 · Cited by 81
Krishna, S., Lin, Z., Serre, C. B. D. L., Wagner, J. J., Harn, D. A., Pepples, L. M., Djani, D. M., Weber, M., Srivastava, L., & Filipov, N. M. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.02.007 · Cited by 77
Sarno, E., Moeser, A. J., & Robison, A. J. (2021) · Advances in pharmacology · doi:10.1016/bs.apha.2021.03.004 · Cited by 84
Anxiety and depression: A top‐down, bottom‐up model of circuit function
LeDuke, D. O., Borio, M., Miranda, R. L., & Tye, K. M. (2023) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14997 · Cited by 76
The antidepressant mechanism of action of vagus nerve stimulation: Evidence from preclinical studies
Grimonprez, A., Raedt, R., Baeken, C., Boon, P., & Vonck, K. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.06.019 · Cited by 81
The antidepressant-like effect of vagus nerve stimulation is mediated through the locus coeruleus
Grimonprez, A., Raedt, R., Portelli, J., Dauwe, I., Larsen, L. E., Bouckaert, C., Delbeke, J., Carrette, E., Meurs, A., Herdt, V. D., et al. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.05.002 · Cited by 74
Ganci, M., Suleyman, E., Butt, H., & Ball, M. (2019) · Brain and Behavior · doi:10.1002/brb3.1408 · Cited by 75
Dunn, M., Henke, A., Clark, S. D., Kovalyova, Y., Kempadoo, K. A., Karpowicz, R. J., Kandel, E. R., Sulzer, D., & Sameš, D. (2018) · Nature Communications · doi:10.1038/s41467-018-05075-x · Cited by 65
Impaired cholesterol metabolism, neurons, and neuropsychiatric disorders
Cheon, S. Y. (2023) · Experimental Neurobiology · doi:10.5607/en23010 · Cited by 67
Melatonergic Receptors (Mt1/Mt2) as a Potential Additional Target of Novel Drugs for Depression
Boiko, D. I., Shkodina, A. D., Hasan, M. M., Bardhan, M., Kazmi, S. K., Chopra, H., Bhutra, P., Baig, A. A., & Skrypnikov, A. M. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03646-5 · Cited by 66
Bi, C., Guo, S., Hu, S., Chen, J., Ye, M., & Liu, Z. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106372 · Cited by 69
Liu, Z., Liu, X., Luo, S., Chu, C., Wu, D., Liu, R., Wang, L., Wang, J., & Liu, X. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.01.005 · Cited by 63
Ludwig, M., Wienke, C., Betts, M. J., Zaehle, T., & Hämmerer, D. (2021) · Autonomic Neuroscience · doi:10.1016/j.autneu.2021.102900 · Cited by 66
Octopamine neuron dependent aggression requires dVGLUT from dual-transmitting neurons
Sherer, L. M., Catudio-Garrett, E. L., Morgan, H. R., Brewer, E. D., Sirrs, L. A., Shearin, H. K., Williams, J. L., McCabe, B. D., Stowers, R. S., & Certel, S. J. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1008609 · Cited by 56
Habibi, B., Pashazadeh, S., Saghatforoush, L. A., & Pashazadeh, A. (2021) · Journal of Electroanalytical Chemistry · doi:10.1016/j.jelechem.2021.115210 · Cited by 59
Tsou, J. Y. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108588485 · Cited by 62
Timberlake, M. A., & Dwivedi, Y. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0241-z · Cited by 59
Gonçalves, A. E., Bürger, C., Amoah, S. K. S., Tolardo, R., Biavatti, M. W., & de Souza, M. M. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.11.009 · Cited by 55
Dissecting the Relationship Between Neuropsychiatric and Neurodegenerative Disorders
Gupta, R. V., Advani, D., Yadav, D., Ambasta, R. K., & Kumar, P. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03502-9 · Cited by 61
Arjunan, A., & Rajan, R. (2020) · Physiology & Behavior · doi:10.1016/j.physbeh.2020.113136 · Cited by 56
Pre-clinical investigations of β-carboline alkaloids as antidepressant agents: A systematic review
Ferraz, C. A. A., Júnior, R. G. D. O., Picot, L., Almeida, J. R. G. D. S., & Nunes, X. P. (2019) · Fitoterapia · doi:10.1016/j.fitote.2019.104196 · Cited by 56
Finnell, J. E., Moffitt, C. M., Hesser, L. A., Harrington, E. N., Melson, M. N., Wood, C. S., & Wood, S. K. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.01.021 · Cited by 49
Pathophysiological relationships between heart failure and depression and anxiety
Chapa, D. W., Akintade, B., Son, H., Woltz, P., Hunt, D., Friedmann, E., Hartung, M. K., & Thomas, S. A. (2014) · Critical Care Nurse · doi:10.4037/ccn2014938 · Cited by 47
Saggu, S., Bai, A., Aida, M., Rehman, H., Pless, A., Ware, D., Deák, F., Jiao, K., & Wang, Q. (2024) · GeroScience · doi:10.1007/s11357-024-01359-x · Cited by 48
Matraszek, R., Chwil, M., Terlecka, P., & Skoczylas, M. M. (2019) · Pharmaceuticals · doi:10.3390/ph12040172 · Cited by 50
Du, X., Yin, M., Yuan, L., Zhang, G., Fan, Y., Li, Z., Yuan, N., Lv, X., Zhao, X., Zou, S., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0808-8 · Cited by 48
Rafi, H., & Zestos, A. G. (2021) · Journal of The Electrochemical Society · doi:10.1149/1945-7111/ac0064 · Cited by 43
A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction
Bell, R. L., Hauser, S. R., Rodd, Z. A., Liang, T., Sari, Y., McClintick, J. N., Rahman, S., & Engleman, E. A. (2016) · International review of neurobiology · doi:10.1016/bs.irn.2016.02.017 · Cited by 46
Yan, J., Kuzhiumparambil, U., Bandodkar, S., Solowij, N., & Fu, S. (2017) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-017-0681-3 · Cited by 45
Baj, J., Bargieł, J., Cabaj, J., Skierkowski, B., Hunek, G., Portincasa, P., Flieger, J., & Smoleń, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242015071 · Cited by 49
Zurawski, Z., Gray, A. D. T., Brady, L. J., Page, B., Church, E., Harris, N. A., Dohn, M. R., Yim, Y. Y., Hyde, K., Mortlock, D. P., et al. (2019) · Science Signaling · doi:10.1126/scisignal.aat8595 · Cited by 43
Buleandră, M., Popa, D. E., David, I. G., & Ciucu, A. A. (2020) · Microchemical Journal · doi:10.1016/j.microc.2020.105621 · Cited by 43
Dekker, A. D., Coppus, A. M. W., Vermeiren, Y., Aerts, T., van Duijn, C. M., Kremer, B. P. H., Naudé, P., Dam, D. V., & Deyn, P. P. D. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-140783 · Cited by 42
Levomilnacipran for the treatment of major depressive disorder: a review
Asnis, G. M., & Henderson, M. (2015) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s54710 · Cited by 42
Liebe, T., Li, M., Čolić, L., Munk, M. H. J., Sweeney‐Reed, C. M., Woelfer, M., Kretzschmar, M., Steiner, J. H., von Düring, F., Behnisch, G., et al. (2018) · NeuroImage Clinical · doi:10.1016/j.nicl.2018.09.001 · Cited by 45
Al-Fartusie, F. S., Al-Bairmani, H. K., Al‐Garawi, Z. S., & Yousif, A. H. (2018) · Biological Trace Element Research · doi:10.1007/s12011-018-1507-7 · Cited by 41
Gut microbiome-gut brain axis-depression: interconnection
Patel, R. A., Panche, A. N., & Harke, S. N. (2024) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2024.2436854 · Cited by 46
Fang, M., Li, Y., Liao, Z., Gan, W., Cao, Q., Li, Y., Duan, Y., Han, Y., Deng, X., Wu, F., et al. (2023) · Immunity · doi:10.1016/j.immuni.2023.02.002 · Cited by 40
Prenatal SSRI exposure: Effects on later child development
Hermansen, T. K., & Melinder, A. (2015) · Child Neuropsychology · doi:10.1080/09297049.2014.942727 · Cited by 38
Major depressive disorder: Biomarkers and biosensors
Dadkhah, M., Jafarzadehgharehziaaddin, M., Molaei, S., Akbari, M., Gholizadeh, N., & Fathi, F. (2023) · Clinica Chimica Acta · doi:10.1016/j.cca.2023.117437 · Cited by 40
Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR
Nyberg, S., Jučaitė, A., Takano, A., Kågedal, M., Cselényi, Z., Halldin, C., & Farde, L. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000680 · Cited by 38
Time course study of microglial and behavioral alterations induced by 6-hydroxydopamine in rats
Silva, T. P. D., Poli, A., Hara, D. B., & Takahashi, R. N. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.04.049 · Cited by 37
Dietary Inflammatory Potential and the Risk of Incident Depression in Adults: A Systematic Review
Kheirouri, S., & Alizadeh, M. (2018) · Advances in Nutrition · doi:10.1093/advances/nmy100 · Cited by 39
Ye, J., Cai, S., Cheung, W. M., & Tsang, H. W. H. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.00574 · Cited by 37
Lago, N., Kaufmann, F. N., Negro‐Demontel, M. L., Alí‐Ruiz, D., Ghisleni, G., Rego, N., Arcas-García, A., Vitureira, N., Jansen, K., Souza, L. M., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1911816117 · Cited by 38
Venlafaxine plus melatonin ameliorate reserpine-induced depression-like behavior in zebrafish
Tang, Y., Li, Z.-R., Zhang, S.-Z., Mi, P., Chen, D.-Y., & Feng, X. (2019) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2019.106835 · Cited by 34
Álvarez-Mon, M. Á., Ortega, M. A., Montero, C. G., Fraile‐Μartinez, O., Monserrat, J., Lahera, G., Mora, F., Rodríguez-Quiroga, A., Fernández-Rojo, S., Quintero, J., et al. (2021) · Pharmaceuticals · doi:10.3390/ph14080821 · Cited by 38
Bidel, F., Poi, C. D., Budzinski, H., Pardon, P. R., Callewaert, W., Arini, A., Basu, N., Dickel, L., Bellanger, C., & Jozet‐Alves, C. (2016) · NeuroToxicology · doi:10.1016/j.neuro.2016.05.023 · Cited by 37
Psychological and neurobiological aspects of suicide in adolescents: Current outlooks
Vargas‐Medrano, J., Diaz-Pacheco, V., Castaneda, C. A., Miranda-Arango, M., Longhurst, M. O., Martin, S. L., Ghumman, U., Mangadu, T., Chheda, S., Thompson, P. M., et al. (2020) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2020.100124 · Cited by 47
Amaghnouje, A., Mechchate, H., Es-safi, I., Boukhira, S., Aliqahtani, A. S., Noman, O. M., Nasr, F. A., Conte, R., Calarco, A., & Bousta, D. (2020) · Molecules · doi:10.3390/molecules25235653 · Cited by 39
Lower Locus Coeruleus MRI intensity in patients with late-life major depression
Guinea-Izquierdo, A., Giménez, M., Martínez‐Zalacaín, I., del Cerro, I., Canal-Noguer, P., Blasco, G., Gascón, J., Reñé, R., Rico, I., Camins, À., et al. (2021) · PeerJ · doi:10.7717/peerj.10828 · Cited by 32
Alberti, A., Coelho, D. R. A., Vieira, W. F., Iser, B. P. M., Lampert, R., Traebert, E., da Silva, B. B., de Oliveira, B. H., Leão, G. M., de Souza, G., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12091994 · Cited by 44
Habenular connectivity may predict treatment response in depressed psychiatric inpatients
Gosnell, S. N., Curtis, K. N., Velasquez, K. M., Fowler, J. C., Madan, A., Goodman, W. K., & Salas, R. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.08.026 · Cited by 33
Liu, L., Zhang, H., Luo, L., Pu, J., Liang, W., Zhu, C., Li, Y., Wang, P., Zhang, Y., Yang, C., et al. (2018) · Chinese Medicine · doi:10.1186/s13020-018-0211-z · Cited by 34
Kangas, E. S., Vuoriainen, E., Lindeman, S. M., & Astikainen, P. (2022) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2022.07.003 · Cited by 33
Coura, R. S., Cressant, A., Xia, J., de Chaumont, F., Olivo‐Marin, J. C., Pelloux, Y., Dalley, J. W., & Granon, S. (2013) · The FASEB Journal · doi:10.1096/fj.13-231084 · Cited by 33
Influence of Gut Microbiota on Mental Health via Neurotransmitters: A Review
Liu, T., Feenstra, K. A., Heringa, J., & Huang, Z. (2020) · Journal of Artificial Intelligence for Medical Sciences · doi:10.2991/jaims.d.200420.001 · Cited by 37
Metadata
- Authors
- Briley, M., & Chantal, M.
- Corresponding author
- Briley, Mike
- Venue
- Neuropsychiatric Disease and Treatment
- Publisher
- Informa UK Limited
- Published
- 2011-05
- Volume
- 7
- Issue
- Suppl 1
- Pages
- 9
- ISSN
- 1176-6328 (ISSN-L)
- PMC
- PMC3131098
- OpenAlex
- W2006526695
- Cited by
- 373
- References
- 49
- Citations by year
- 2026: 9 · 2025: 32 · 2024: 37 · 2023: 40 · 2022: 27 · 2021: 54 · 2020: 31 · 2019: 34 · 2018: 31 · 2017: 21 · 2016: 17 · 2015: 14 · 2014: 13 · 2013: 7 · 2012: 4
- FWCI
- 6.09
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Neuropsychiatric Disease and Treatment (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Keywords
- norepinephrine, depression, monoamine neurotransmission, serotonin, dopamine, antidepressant mechanism, norepinephrine reuptake inhibition, monoamine oxidase inhibition, executive function, motivation, social dysfunction, quality of life
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
