Nonaggressive and adapted social cognition is controlled by the interplay between noradrenergic and nicotinic receptor mechanisms in the prefrontal cortex
Open accessAbstract
Social animals establish flexible behaviors and integrated decision‐making processes to adapt to social environments. Such behaviors are impaired in all major neuropsychiatric disorders and depend on the prefrontal cortex (PFC). We previously showed that nicotinic acetylcholine receptors (nAChRs) and norepinephrine (NE) in the PFC are necessary for mice to show adapted social cognition. Here, we investigated how the cholinergic and NE systems converge within the PFC to modulate social behavior. We used a social interaction task (SIT) in C57BL/6 mice and mice lacking β2*nAChRs (β2 –/– mice), making use of dedicated software to analyze >20 social sequences and pinpoint social decisions. We performed specific PFC NE depletions before SIT and measured monoamines and acetylcholine (ACh) levels in limbic corticostriatal circuitry. After PFC‐NE depletion, C57BL/6 mice exhibited impoverished and more rigid social behavior and were 6‐fold more aggressive than sham‐lesioned animals, whereas β2 –/– mice showed unimpaired social behavior. Our biochemical measures suggest a critical involvement of DA in SIT. In addition, we show that the balance between basal levels of monoamines and of ACh modulates aggressiveness and this modulation requires functional β2*nAChRs. These findings demonstrate the critical interplay between prefrontal NE and nAChRs for the development of adapted and nonaggressive social cognition.—Coura, R. S., Cressant, A, Xia, J., de Chaumont, F., Olivo‐Marin, J. C., Pelloux, Y., Dalley, J. W., Granon, S. Nonaggressive and adapted social cognition is controlled by the interplay between noradrenergic and nicotinic receptor mechanisms in the prefrontal cortex. FASEB J . 27, 4343–4354 (2013). www.fasebj.org
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At baseline, β2−/− mice exhibit increased levels of norepinephrine, dopamine, serotonin, and acetylcholine within the prelimbic region of the PFC, yet display similar levels of aggression compared to control mice both before and after global norepinephrine depletion.
“At baseline, β2−/− mice exhibit increased levels of norepinephrine, dopamine, serotonin, and acetylcholine within the prelimbic region of the PFC, yet display similar levels of aggression compared to control mice both before and after global norepinephrine depletion.”
From Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states (2015) · cites this paper as Coura et al., 2013
Specific norepinephrine depletion in the prelimbic region of the PFC markedly increased aggression in control, but not β2−/− mice.
“Specific norepinephrine depletion in the prelimbic region of the PFC markedly increased aggression in control, but not β2−/− mice”
From Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states (2015) · cites this paper as Coura et al., 2013
Aggression was modulated by the balance of monoamines and acetylcholine in the prelimbic cortex, and requires functional β2 nAChRs.
“a finding that suggests aggression was modulated by the balance of monoamines and acetylcholine in the prelimbic cortex, and requires functional β2 nAChRs (Coura et al., 2013)”
From Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states (2015) · cites this paper as Coura et al., 2013
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Cites
The Mouse Brain in Stereotaxic Coordinates
Paxinos, G. (2001) · Cited by 12,859 · see citing works
The reorienting system of the human brain: from environment to theory of mind
Corbetta, M., Patel, G., & Shulman, G. L. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.017 · Cited by 3,889 · see citing works
Fett, A.-K. J., Viechtbauer, W., Dominguez, M.-D.-G., Penn, D. L., van Os, J., & Krabbendam, L. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.07.001 · Cited by 1,833 · see citing works
Uncertainty, Neuromodulation, and Attention
Yu, A. J., & Dayan, P. (2005) · Neuron · doi:10.1016/j.neuron.2005.04.026 · Cited by 1,774 · see citing works
Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates
Dalley, J. W., Cardinal, R. N., & Robbins, T. W. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.09.006 · Cited by 1,329 · see citing works
Self-citationPicciotto, M. R., Zoli, M., Rimondini, R., Léna, C., Marubio, L. M., Pich, E. M., Fuxe, K., & Changeux, J.-P. (1998) · Nature · doi:10.1038/34413 · Cited by 1,320 · see citing works
The cholinergic system in aging and neuronal degeneration
Schliebs, R., & Arendt, T. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.11.058 · Cited by 1,047 · see citing works
Neurobiology of Executive Functions: Catecholamine Influences on Prefrontal Cortical Functions
Arnsten, A. F. T., & Li, B.-M. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.08.019 · Cited by 948 · see citing works
(2000) · Cited by 919 · see citing works
Role of locus coeruleus in attention and behavioral flexibility
Aston-Jones, G., Rajkowski, J., & Cohen, J. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00140-7 · Cited by 900 · see citing works
Brain nicotinic acetylcholine receptors: native subtypes and their relevance
Gotti, C., Zoli, M., & Clementi, F. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2006.07.004 · Cited by 882 · see citing works
Hisano, S., Hoshi, K., Ikeda, Y., Maruyama, D., Kanemoto, M., Ichijo, H., Kojima, I., Takeda, J., & Nogami, H. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00194-7 · Cited by 806 · see citing works
Network reset: a simplified overarching theory of locus coeruleus noradrenaline function
Bouret, S., & Sara, S. J. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.09.002 · Cited by 806 · see citing works
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
Taly, A., Corringer, P., Guédin, D., Lestage, P. J., & Changeux, J. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2927 · Cited by 706 · see citing works
Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain
Picciotto, M. R., Zoli, M., Léna, C., Bessis, A., Lallemand, Y., LeNovère, N., Vincent, P., Pich, E. M., Brûlet, P., & Changeux, J.-P. (1995) · Nature · doi:10.1038/374065a0 · Cited by 668 · see citing works
Adaptive gain and the role of the locus coeruleus–norepinephrine system in optimal performance
Aston‐Jones, G., & Cohen, J. D. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20723 · Cited by 630 · see citing works
Evolution of a Vertebrate Social Decision-Making Network
O’Connell, L. A., & Hofmann, H. A. (2012) · Science · doi:10.1126/science.1218889 · Cited by 608 · see citing works
Pathophysiology of depression: do we have any solid evidence of interest to clinicians?
HASLER, G. (2010) · World Psychiatry · doi:10.1002/j.2051-5545.2010.tb00298.x · Cited by 604 · see citing works
Endogenous nicotinic cholinergic activity regulates dopamine release in the striatum
Zhou, F.-M., Liang, Y., & Dani, J. A. (2001) · Nature Neuroscience · doi:10.1038/nn769 · Cited by 585 · see citing works
Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors
Maskos, U., Molles, B. E., Pons, S., Besson, M., Guiard, B. P., Guilloux, J.-P., Evrard, A., Cazala, P., Cormier, A., Mameli-Engvall, M., et al. (2005) · Nature · doi:10.1038/nature03694 · Cited by 566 · cited 1× · see citing works
“the 2-subunit of the nAChRs specifically into the PFC of 2 / mice was sufficient to restore normal social patterns in these animals, thus showing that 2 / social defects were not due to gross compensatory mechanisms (24, 34, 35).”
BackgroundJamain, S., Radyushkin, K., Hammerschmidt, K., Granon, S., Boretius, S., Varoqueaux, F., Ramanantsoa, N., Gallego, J., Ronnenberg, A., Winter, D., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711555105 · Cited by 556 · see citing works
The Pathophysiology of Schizophrenia Disorders: Perspectives From the Spectrum
Siever, L. J., & Davis, K. L. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.3.398 · Cited by 510 · see citing works
Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background
Silva, A. J., Simpson, E. M., Takahashi, J. S., Lipp, H.-P., Nakanishi, S., Wehner, J. M., Giese, K. P., Tully, T., Abel, T., Chapman, P. F., et al. (1997) · Neuron · doi:10.1016/s0896-6273(00)80958-7 · Cited by 479 · see citing works
Rorabacher, D. B. (1991) · Analytical Chemistry · doi:10.1021/ac00002a010 · Cited by 450 · see citing works
Le Novère, N., Corringer, P., & Changeux, J. (2002) · Journal of Neurobiology · doi:10.1002/neu.10153 · Cited by 411 · see citing works
Variation in dopamine genes influences responsivity of the human reward system
Dreher, J.-C., Kohn, P., Kolachana, B., Weinberger, D. R., & Berman, K. F. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805517106 · Cited by 376 · see citing works
The importance of norepinephrine in depression
Briley, M., & Chantal, M. (2011) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s19619 · Cited by 373 · see citing works
Nutt, D., Demyttenaere, K., Janka, Z., Aarre, T., Bourin, M., Canonico, P. L., Carrasco, J. L., & Stahl, S. (2007) · Journal of Psychopharmacology · doi:10.1177/0269881106069938 · Cited by 366 · see citing works
Cholinergic Hyperactivity and Negative Schizophrenic Symptoms
Tandon, R. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810080075010 · Cited by 354 · see citing works
Phasic norepinephrine: A neural interrupt signal for unexpected events
Dayan, P., & Yu, A. J. (2006) · Network Computation in Neural Systems · doi:10.1080/09548980601004024 · Cited by 302 · see citing works
SOCIAL ORGANIZATION AND TERRITORIAL BEHAVIOUR IN THE
CROWCROFT, P., & ROWE, F. P. (1963) · Proceedings of the Zoological Society of London · doi:10.1111/j.1469-7998.1963.tb01871.x · Cited by 286 · see citing works
Marshall, D. L., Redfern, P. H., & Wonnacott, S. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.68041511.x · Cited by 284 · see citing works
Systematic review of the neural basis of social cognition in patients with mood disorders
Cusi, A. M., Nazarov, A., Holshausen, K., MacQueen, G. M., & McKinnon, M. C. (2012) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.100179 · Cited by 278 · see citing works
Dalley, J. W., McGaughy, J., O'Connell, M. T., Cardinal, R. N., Levita, L., & Robbins, T. W. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-13-04908.2001 · Cited by 277 · see citing works
Dalley, J. W. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00412-2 · Cited by 271 · see citing works
Computerized video analysis of social interactions in mice
de Chaumont, F., Coura, R., Serreau, P., Cressant, A., Chabout, J., Granon, S., & Olivo‐Marín, J. (2012) · Nature Methods · doi:10.1038/nmeth.1924 · Cited by 238 · see citing works
Vizi, E. S., & Lendvai, B. (1999) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00016-8 · Cited by 228 · see citing works
McGaughy, J., Ross, R. S., & Eichenbaum, H. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.01.064 · Cited by 226 · see citing works
Modulators in concert for cognition: Modulator interactions in the prefrontal cortex
Briand, L. A., Gritton, H., Howe, W. M., Young, D. A., & Sarter, M. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.06.007 · Cited by 216 · see citing works
Cholinergic modulation of the cortical neuronal network
Lucas-Meunier, E., Fossier, P., Baux, G., & Amar, M. (2003) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-002-0999-2 · Cited by 207 · see citing works
Nicotinic modulation of neuronal networks: from receptors to cognition
Mansvelder, H. D., van Aerde, K. I., Couey, J. J., & Brussaard, A. B. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0070-z · Cited by 201 · see citing works
Tóth, E., Sershen, H. W., Hashim, A. T., Vizi, E. S., & Lajtha, Á. (1992) · Neurochemical Research · doi:10.1007/bf00966669 · Cited by 194 · see citing works
Stopping behavior: constraints on exploration in rats (Rattus norvegicus)
Golani, I., Benjamini, Y., & Eilam, D. (1993) · Behavioural Brain Research · doi:10.1016/s0166-4328(05)80263-3 · Cited by 192 · see citing works
Nicotinic acetylcholine receptor β2 subunits in the medial prefrontal cortex control attention
Guillem, K., Bloem, B., Poorthuis, R. B., Loos, M., Smit, A. B., Maskos, U., Spijker, S., & Mansvelder, H. D. (2011) · Science · doi:10.1126/science.1207079 · Cited by 191 · see citing works
Chabout, J., Serreau, P., Ey, E., Bellier, L., Aubin, T., Bourgeron, T., & Granon, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029401 · Cited by 186 · see citing works
Lesions of the dorsal noradrenergic bundle impair attentional set-shifting in the rat
Tait, D. S., Brown, V. J., Farovik, A., Theobald, D. E., Dalley, J. W., & Robbins, T. W. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05612.x · Cited by 179 · see citing works
Testosterone and aggressiveness.
Giammanco, M., Tabacchi, G., Giammanco, S., Majo, D. D., & Guardia, M. L. (2005) · PubMed · Cited by 175 · see citing works
Executive and social behaviors under nicotinic receptor regulation
Granon, S., Fauré, P., & Changeux, J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1533498100 · Cited by 166 · see citing works
Proposal for a noradrenaline hypothesis of schizophrenia
Yamamoto, K.-I., & Hornykiewicz, O. (2004) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.05.033 · Cited by 155 · see citing works
Neural Systems Underlying Arousal and Attention: Implications for Drug Abusea
Robbins, T. W., Granon, S., Muir, J. L., Durantou, F., Harrison, A. A., & Everitt, B. J. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09740.x · Cited by 149 · see citing works
Kohls, G., Peltzer, J., Herpertz‐Dahlmann, B., & Konrad, K. (2009) · Developmental Science · doi:10.1111/j.1467-7687.2009.00816.x · Cited by 145 · see citing works
Granon, S., Poucet, B., Thinus‐Blanc, C., Changeux, J., & Vidal, C. (1995) · Psychopharmacology · doi:10.1007/bf02246154 · Cited by 141 · see citing works
Nicotinic acetylcholine receptors and the ascending dopamine pathways
Livingstone, P. D., & Wonnacott, S. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.06.004 · Cited by 131 · see citing works
Gamo, N. J., & Arnsten, A. F. T. (2011) · Behavioral Neuroscience · doi:10.1037/a0023165 · Cited by 124 · see citing works
Cholinergic connectivity: it's implications for psychiatric disorders
Scarr, E., Gibbons, A. S., Neo, J. H., Udawela, M., & Dean, B. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00055 · Cited by 117 · see citing works
Prefrontal nicotinic receptors control novel social interaction between mice
Avale, M. E., Chabout, J., Pons, S., Serreau, P., De Chaumont, F., Olivo‐Marin, J., Bourgeois, J., Maskos, U., Changeux, J., & Granon, S. (2011) · The FASEB Journal · doi:10.1096/fj.10-178558 · Cited by 114 · see citing works
Self-citationAllosteric Receptors: From Electric Organ to Cognition
Changeux, J. (2010) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.010909.105741 · Cited by 109 · see citing works
Parallel Loss of Hippocampal LTD and Cognitive Flexibility in a Genetic Model of Hyperdopaminergia
Morice, É., Billard, J., Denis, C., Mathieu, F., Betancur, C., Epelbaum, J., Giros, B., & Nosten‐Bertrand, M. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301354 · Cited by 107 · see citing works
Dementia rating and nicotinic receptor expression in the prefrontal cortex in schizophrenia
Martin-Ruiz, C. M., Haroutunian, V. H., Long, P., Young, A. H., Davis, K. L., Perry, E. K., & Court, J. A. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00348-2 · Cited by 100 · see citing works
Sources of Variability and Systematic Error in Mouse Timing Behavior.
Gallistel, C. R., King, A. P., & McDonald, R. (2004) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/0097-7403.30.1.3 · Cited by 97 · see citing works
Prefrontal Norepinephrine Determines Attribution of “High” Motivational Salience
Ventura, R., Latagliata, E. C., Morrone, C., Mela, I. L., & Puglisi‐Allegra, S. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003044 · Cited by 94 · see citing works
Siuta, M., Robertson, S. D., Kocalis, H. E., Saunders, C., Gresch, P. J., Khatri, V., Shiota, C., Kennedy, J. P., Lindsley, C. W., Daws, L. C., et al. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000393 · Cited by 92 · see citing works
Layne, J. E., Barnes, W. J. P., & Duncan, L. M. J. (2003) · Journal of Experimental Biology · doi:10.1242/jeb.00661 · Cited by 89 · see citing works
Interplay of β2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion
Avale, M. E., Fauré, P., Pons, S., Robledo, P., Deltheil, T., David, D. J. P., Gardier, A. M., Maldonado, R. J., Granon, S., Changeux, J., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807635105 · Cited by 78 · see citing works
Frontal cortical α7 and α4β2 nicotinic acetylcholine receptors in working and reference memory
Chan, W. K., Wong, P. T.-H., & Sheu, F. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2007.03.008 · Cited by 70 · see citing works
Nicotinic Acetylcholine Receptor Regulation of Spinal Norepinephrine Release
Li, X., & Eisenach, J. C. (2002) · Anesthesiology · doi:10.1097/00000542-200206000-00026 · Cited by 57 · see citing works
Azam, L., & McIntosh, J. M. (2006) · Molecular Pharmacology · doi:10.1124/mol.106.024513 · Cited by 56 · see citing works
Prefrontal neuromodulation by nicotinic receptors for cognitive processes
Coura, R., & Granon, S. (2012) · Psychopharmacology · doi:10.1007/s00213-011-2596-6 · Cited by 51 · see citing works
Attention-deficit/hyperactivity disorder: A plausible mouse model?
Granon, S., & Changeux, J. (2006) · Acta Paediatrica · doi:10.1080/08035250600719747 · Cited by 49 · see citing works
O’Leary, O. F., Bechtholt, A. J., Crowley, J. J., Valentino, R. J., & Lucki, I. (2006) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.06.012 · Cited by 45 · see citing works
Behavioral Sequence Analysis Reveals a Novel Role for ß2* Nicotinic Receptors in Exploration
Maubourguet, N., Lesne, A., Changeux, J., Maskos, U., & Fauré, P. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000229 · Cited by 43 · see citing works
O'Leary, K. T., & Leslie, F. M. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01575.x · Cited by 42 · see citing works
Effects of testosterone on attention and memory for emotional stimuli in male rhesus monkeys
King, H. M., Kurdziel, L. B. F., Meyer, J. S., & Agnès Lacreuse, A. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.07.010 · Cited by 42 · see citing works
Briley, M. S., & Changeux, J. (1977) · International review of neurobiology · doi:10.1016/s0074-7742(08)60650-9 · Cited by 39 · see citing works
Maloku, E., Kadriu, B., Zhubi, A., Dong, E., Pibiri, F., Satta, R., & Guidotti, A. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.21 · Cited by 37 · see citing works
Frånberg, O., Marcus, M. M., & Svensson, T. H. (2012) · Synapse · doi:10.1002/syn.21551 · Cited by 37 · see citing works
Cambon, K., Coura, R., Groc, L., Carbon, A., Weissmann, D., Changeux, J., Pujol, J. F., & Granon, S. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.09.015 · Cited by 36 · see citing works
Audet, M., & Anisman, H. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709990174 · Cited by 33 · see citing works
Bourgeois, J., Meas‐Yedid, V., Sourd, A. L., Fauré, P., Pons, S., Maskos, U., Changeux, J., Olivo‐Marín, J., & Granon, S. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr159 · Cited by 28 · see citing works
Serreau, P., Chabout, J., Suárez, S., Naudé, J., & Granon, S. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.07.016 · Cited by 21 · see citing works
O’Leary, K. T., & Leslie, F. M. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.08.013 · Cited by 13 · see citing works
Attention‐deficit/hyperactivity disorder: A plausible mouse model?
Granon, S., & Changeux, J. (2006) · Acta Paediatrica · doi:10.1111/j.1651-2227.2006.tb02310.x · Cited by 7 · see citing works
Flagged first, then by citations
1 of the 83 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- [7]Granon S. Floresco S. (2009) Functional neuroanatomy of flexible behaviors in mice and rats. In Endophenotypes of Psychiatric and Neurodegenerative Disorders in Rodent Models (Granon S., ed.) pp. 83– 103, Transworld Research Network, Kerala, India
Cited by
Sorted by citations
Picciotto, M. R., Lewis, A. S., van Schalkwyk, G. I., & Mineur, Y. S. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.12.028 · Cited by 157 · see citing works
Simola, N., & Granon, S. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.11.008 · Cited by 156 · see citing works
Costas‐Ferreira, C., & Faro, L. R. F. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168413 · Cited by 156 · see citing works
Miranda, R., Nagapin, F., Bozon, B., Laroche, S., Aubin, T., & Vaillend, C. (2015) · Molecular Autism · doi:10.1186/s13229-015-0053-9 · Cited by 44 · see citing works
Social behaviors and acoustic vocalizations in different strains of mice
Faure, A., Pittaras, E., Nosjean, A., Chabout, J., Cressant, A., & Granon, S. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.11.003 · Cited by 44 · see citing works
Altered social behavior in mice carrying a corticalFoxp2deletion
Medvedeva, V. P., Rieger, M. A., Vieth, B., Mombereau, C., Ziegenhain, C., Ghosh, T., Cressant, A., Enard, W., Granon, S., Dougherty, J. D., et al. (2018) · Human Molecular Genetics · doi:10.1093/hmg/ddy372 · Cited by 40 · see citing works
Modulation of aggressive behavior in mice by nicotinic receptor subtypes
Lewis, A. S., Mineur, Y. S., Smith, P. H., Cahuzac, E. L. M., & Picciotto, M. R. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.07.019 · Cited by 36 · see citing works
Evolutionary themes in the neurobiology of social cognition
Weitekamp, C. A., & Hofmann, H. A. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.06.005 · Cited by 35 · see citing works
Zhang, Q., Goto, H., Nishimura-Akiyoshi, S., Prosselkov, P. V., Sano, C., Matsukawa, H., Yaguchi, K., Nakashiba, T., & Itohara, S. (2016) · Molecular Brain · doi:10.1186/s13041-016-0187-5 · Cited by 33 · see citing works
Ahmed, M. A. E., & Awdan, S. A. E. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.07.007 · Cited by 30 · see citing works
A multiscale analysis in CD38 −/− mice unveils major prefrontal cortex dysfunctions
Martucci, L. L., Amar, M., Chaussenot, R., Benet, G., Bauer, O., de Zélicourt, A., Nosjean, A., Launay, J., Callebert, J., Sebrié, C., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201800489r · Cited by 29 · see citing works
Chabout, J., Cressant, A., Hu, M. X., Edeline, J., & Granon, S. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00468 · Cited by 30 · see citing works
Pittaras, E., Faure, A., Leray, X., Moraitopoulou, E., Cressant, A., Rabat, A., Meunier, C. N. J., Fossier, P., & Granon, S. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00171 · Cited by 29 · see citing works
Nosjean, A., Cressant, A., de Chaumont, F., Olivo‐Marín, J., Chauveau, F., & Granon, S. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00447 · Cited by 24 · see citing works
Lewis, A. S., & Picciotto, M. R. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.107929 · Cited by 23 · see citing works
Cholinergic transmission from the basal forebrain modulates social memory in male mice
Kljakic, O., Al‐Onaizi, M., Janíčková, H., Chen, K. S., Guzman, M. S., Prado, M. A. M., & Prado, V. F. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15400 · Cited by 22 · see citing works
Environmental insults in early life and submissiveness later in life in mouse models
Benner, S., Endo, T., Kakeyama, M., & Tohyama, C. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00091 · Cited by 19 · see citing works
Faure, A., Nosjean, A., Pittaras, E., Duchêne, A., Andrieux, A., Gory‐Fauré, S., Charvériat, M., & Granon, S. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.09.009 · Cited by 18 · see citing works
Matsumoto, Y., Niwa, M., Mouri, A., Noda, Y., Fukushima, T., Ozaki, N., & Nabeshima, T. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4704-8 · Cited by 15 · see citing works
Neurophysiological functions and pharmacological tools of acidic and non-acidic Ca2+ stores
Martucci, L. L., & Cancela, J. (2022) · Cell Calcium · doi:10.1016/j.ceca.2022.102582 · Cited by 11 · see citing works
Costa, G., Serra, M., & Simola, N. (2021) · Brain Sciences · doi:10.3390/brainsci11081053 · Cited by 10 · see citing works
Characterization of social behavior in young and middle-aged ChAT-IRES-Cre mouse
Lhopitallier, C., Perrault, C., Chauveau, F., Saurini, F., Berrard, S., Granon, S., & Faure, A. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272141 · Cited by 7 · see citing works
Faure, A., Zoratto, F., Chirico, D., Romano, E., Mancinelli, R., Saso, L., Callebert, J., Giovanni Laviola, A., Granon, S., & Adriani, W. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.06.014 · Cited by 6 · see citing works
The role of the prefrontal cortex in modulating aggression in humans and rodents
Li, X., Xiong, L., & Li, Y. (2024) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.115285 · Cited by 4 · see citing works
Why does lifelong conventional housing reduce the sociability of female mice?
Kitchenham, L., Nazal, B., Adcock, A., Nip, E., MacLellan, A., & Mason, G. J. (2021) · Applied Animal Behaviour Science · doi:10.1016/j.applanim.2021.105532 · Cited by 4 · see citing works
Stress-induced brain activation: buffering role of social behavior and neuronal nicotinic receptors
Nosjean, A., de Chaumont, F., Olivo‐Marín, J., & Granon, S. (2018) · Brain Structure and Function · doi:10.1007/s00429-018-1745-7 · Cited by 5 · see citing works
Brain adaptation to acute stress: effect of time, social buffering, and nicotinic cholinergic system
Nosjean, A., & Granon, S. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab461 · Cited by 4 · see citing works
Boukersi, H., Lebaïli, N., Nosjean, A., Samson-Desvignes, N., Faure, A., & Granon, S. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.113022 · Cited by 2 · see citing works
Mirofle, N., Jamain, S., Chauveau, F., Penot, M., Chater, D., Latapie, V., Deneux, T., Faure, A., & Granon, S. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.23.684125
Silva, A. H. B. D. L., de Oliveira, P. H. A., da Cunha, J. M., Zanoveli, J. M., & Martynhak, B. J. (2025) · Neuropharmacology · doi:10.1016/j.neuropharm.2025.110749
Dobrigna, M., Poëa‐Guyon, S., Legras, M., Verger, D. L., Duarte, K., Sebrié, C., Poirier, R., Granon, S., Marty, S., Toutain, A., et al. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.107188
New regulators in oxytocin and vasopressin release : role of the endolysosomal two-pore channels
Martucci, L. L. (2021) · theses.fr (ABES) · doi:10.70675/027d1ae2zd2ebz4677za019ze6ccd94cafe9
- Authors
- Coura, R. S., Cressant, A., Xia, J., de Chaumont, F., Olivo‐Marin, J. C., Pelloux, Y., Dalley, J. W., & Granon, S.
- Affiliations
- Université Paris-Sud (FR)
- University of Cambridge (GB)
- Institut Pasteur Unité d'Analyse d'Images Quantitative Centre National de la Recherche Scientifique Unité de Recherche Associée 2582 Paris France
- Corresponding author
- Granon, Sylvie
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 2013-07-23
- Volume
- 27
- Issue
- 11
- Pages
- 4343-4354
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- PMC
- PMC3977319
- OpenAlex
- W2033658160
- Cited by
- 33
- References
- 83
- Citations by year
- 2025: 3 · 2024: 2 · 2022: 2 · 2021: 6 · 2020: 1 · 2019: 3 · 2018: 4 · 2017: 1 · 2016: 3 · 2015: 6 · 2014: 1 · 2013: 1
- FWCI
- 1.64
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- The FASEB Journal (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Centre National de la Recherche Scientifique
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- social cognition, social aggression, prefrontal cortex, nicotinic acetylcholine receptors, norepinephrine, dopamine, monoamines, acetylcholine, social decision-making, corticostriatal circuits
- MeSH terms
- Acetylcholine, Aggression, Animals, Cognition, Decision Making, Male, Mice, Inbred C57BL, Norepinephrine, Receptors, Adrenergic, Receptors, Nicotinic, Prefrontal Cortex, Mice, Knockout, Mice
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