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Cited by 760

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention

Open access
Munoz·2009·Vascular Health and Risk Management
DOI 10.2147/vhrm.s6269
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Abstract

Low-density lipoprotein (LDL) cholesterol concentration has been the prime index of cardiovascular disease risk and the main target for therapy. However, several lipoprotein ratios or "atherogenic indices" have been defined in an attempt to optimize the predictive capacity of the lipid profile. In this review, we summarize their pathophysiological aspects, and highlight the rationale for using these lipoprotein ratios as cardiovascular risk factors in clinical practice, specifying their cut-off risk levels and a target for lipid-lowering therapy. Total/high-density lipoprotein (HDL) cholesterol and LDL/HDL cholesterol ratios are risk indicators with greater predictive value than isolated parameters used independently, particularly LDL. Future recommendations regarding the diagnosis and treatment of dyslipidemia, including instruments for calculating cardiovascular risk or action guidelines, should include the lipoprotein ratios with greater predictive power which, in view of the evidence-based results, are none other than those which include HDL cholesterol.

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Metadata

Authors
Munoz
Venue
Vascular Health and Risk Management
Publisher
Informa UK Limited
Published
2009-09
Volume
5
Pages
757
ISSN
  • 1176-6344 (ISSN-L)
  • 1178-2048
DOI
10.2147/vhrm.s6269
OpenAlex
W2166117607
Cited by
760
References
8
FWCI
11.07
Type
journal article
Language
en
Open access
gold

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.