The Efficacy and Therapeutic Alliance of Augmented Reality Exposure Therapy in Treating Adults With Phobic Disorders: Systematic Review
Open accessPublished version of a preprint
Abstract
Background: Phobic disorders are characterized by excessive fear of a stimulus that can affect the quality of a patient’s life. The lifetime prevalence in adults is 7.7% to 12.5%. The current literature provides evidence-based inferences about the effectiveness of in-vivo exposure therapy (IVET) in treating phobia. However, this method can put the therapist and the client in danger, with high drop out and refusal rates. A newer approach for exposure therapy using augmented reality technology is under assessment. Objective: This systematic review investigated the novel technology’s efficacy, cost-efficacy, and therapeutic alliance in treating adults with phobia. Methods: An extensive search was conducted using 4 major databases (MEDLINE, PsycINFO, Embase, and Scopus) using a comprehensive list of synonyms for augmented reality exposure therapy (ARET) and phobic disorders. The search targeted any randomized control trial testing ARET in adults with phobic disorders up to August 8, 2022. Results: A total of 6 studies were included, with 208 participants providing results. Studies investigating the efficacy of ARET compared to no intervention showed significant results (P<.05) in the ARET group improvement. Head-to-head comparative studies comparing ARET to IVET showed no significant difference (P>.05) in the effectiveness and therapeutic alliance between both therapies. Further, the results demonstrated that the ARET group had a better long-term effect than IVET, with the ability to put the patients in more situations to face the feared object. Conclusions: The current data suggest clinically significant efficacy and a promising therapeutic alliance of ARET. However, no data are available investigating the cost-effectiveness of ARET. Further research is warranted to ascertain ARET’s cost-effectiveness and examine its efficacy in other populations and anxiety conditions.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
IMTs have proven effective in treating a wide range of mental health conditions, such as anxiety, PTSD, autism spectrum disorders, and various phobias.
“Moreover, IMTs have proven effective in treating a wide range of mental health conditions, such as anxiety, posttraumatic stress disorder, autism spectrum disorders, and various phobias [15-22].”
From Immersive technologies for depression care: scoping review (2024) · cites this paper as [15]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works
The PRISMA 2020 statement: An updated guideline for reporting systematic reviews
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., et al. (2021) · BMJ · doi:10.1136/bmj.n71 · Cited by 108,283 · see citing works
Factor structure of the working alliance inventory
Tracey, T. J., & Kokotovic, A. M. (1989) · Psychological Assessment: A Journal of Consulting and Clinical Psychology · doi:10.1037/1040-3590.1.3.207 · Cited by 1,501 · see citing works
Moltu, C., Stefansen, J., Svisdahl, M., & Veseth, M. (2012) · Disability and Rehabilitation · doi:10.3109/09638288.2012.656792 · Cited by 1,247 · see citing works
Baldwin, D. S., Anderson, I. M., Nutt, D. J., Allgulander, C., Bandelow, B., den Boer, J. A., Christmas, D. M., Davies, S., Fineberg, N., Lidbetter, N., et al. (2014) · Journal of Psychopharmacology · doi:10.1177/0269881114525674 · Cited by 676 · see citing works
Treatment of specific phobia in adults
Choy, Y., Fyer, A. J., & Lipsitz, J. D. (2007) · Clinical Psychology Review · doi:10.1016/j.cpr.2006.10.002 · Cited by 573 · cited 2× · see citing works
“Different modalities of cognitive behavioral therapy (CBT) can be used, although CBT with exposure is believed to be the most effective treatment [6,7].”
BackgroundMethodFear of spiders’ questionnaire
Szymanski, J., & O'Donohue, W. (1995) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/0005-7916(94)00072-t · Cited by 450 · cited 1× · see citing works
“At the same time, FSQ and the SPBQ are ideally used together to cover the gaps in SPBQ [27].”
MethodRiva, G., Baños, R. M., Botella, C., Mantovani, F., & Gaggioli, A. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00164 · Cited by 425 · see citing works
(2020) · doi:10.12788/acp · Cited by 401 · see citing works
Baus, O., & Bouchard, S. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00112 · Cited by 260 · see citing works
Grey Literature: Its Emerging Importance
Pappas, C., & Williams, I. (2011) · Journal of Hospital Librarianship · doi:10.1080/15323269.2011.587100 · Cited by 175 · see citing works
Effect of multiple context exposure on renewal in spider phobia
Shiban, Y., Pauli, P., & Mühlberger, A. (2013) · Behaviour Research and Therapy · doi:10.1016/j.brat.2012.10.007 · Cited by 162 · see citing works
Miloff, A., Lindner, P., Dafgård, P., Deak, S., Garke, M., Hamilton, W., Heinsoo, J., Kristoffersson, G., Rafi, J., Sindemark, K., et al. (2019) · Behaviour Research and Therapy · doi:10.1016/j.brat.2019.04.004 · Cited by 155 · see citing works
Augmented Reality: A Brand New Challenge for the Assessment and Treatment of Psychological Disorders
Giglioli, I. A. C., Pallavicini, F., Pedroli, E., Serino, S., & Riva, G. (2015) · Computational and Mathematical Methods in Medicine · doi:10.1155/2015/862942 · Cited by 150 · see citing works
Ng, Y.-L., Ma, F., Ho, F. K. W., Ip, P., & Fu, K. (2019) · Computers in Human Behavior · doi:10.1016/j.chb.2019.05.026 · Cited by 148 · see citing works
Shiban, Y., Schelhorn, I., Pauli, P., & Mühlberger, A. (2015) · Behaviour Research and Therapy · doi:10.1016/j.brat.2015.05.014 · Cited by 141 · see citing works
Technology-Based Mental Health Treatment and the Impact on the Therapeutic Alliance
Lopez, A., Schwenk, S., Schneck, C. D., Griffin, R. J., & Mishkind, M. C. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1055-7 · Cited by 128 · see citing works
Botella, C., Pérez-Ara, M. Á., Bretón-López, J., Quero, S., García-Palacios, A., & Baños, R. M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148237 · Cited by 124 · cited 5× · see citing works
“Botella et al’s [28] results revealed a positive effect on the long-term efficacy of ARET, with regression in the impact of IVET.”
BackgroundMethodInfluentialPhobia Exposure Therapy Using Virtual and Augmented Reality: A Systematic Review
Albakri, G., Bouaziz, R., Alharthi, W. J., Kammoun, S., Al-Sarem, M., Saeed, F., & Hadwan, M. (2022) · Applied Sciences · doi:10.3390/app12031672 · Cited by 113 · see citing works
Kipper, G. (2013) · Elsevier eBooks · doi:10.1016/b978-1-59-749733-6.00001-2 · Cited by 100 · see citing works
Companion to Psychiatric Studies
Torem, M. S. (1985) · JAMA · doi:10.1001/jama.1985.03350380155041 · Cited by 97 · see citing works
The therapeutic alliance: the fundamental element of psychotherapy
Stubbe, D. E. (2018) · Focus · doi:10.1176/appi.focus.20180022 · Cited by 97 · see citing works
Extinction in multiple virtual reality contexts diminishes fear reinstatement in humans
Dunsmoor, J. E., Ahs, F., Zielinski, D. J., & LaBar, K. S. (2014) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2014.02.010 · Cited by 93 · see citing works
Tsai, C.-F., Yeh, S., Huang, Y., Wu, Z., Cui, J., & Zheng, L. (2018) · Journal of Healthcare Engineering · doi:10.1155/2018/6357351 · Cited by 59 · see citing works
The clinical potential of augmented reality.
Vinci, C., Brandon, K. O., Kleinjan, M., & Brandon, T. H. (2020) · Clinical Psychology Science and Practice · doi:10.1111/cpsp.12357 · Cited by 49 · see citing works
Zimmer, A., Wang, N., Ibach, M. K., Fehlmann, B., Schicktanz, N., Bentz, D., Michael, T., Papassotiropoulos, A., & de Quervain, D. D. (2021) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2021.102442 · Cited by 44 · see citing works
Wrzesien, M., Burkhardt, J.-M., Alcañiz, M., & Botella, C. (2011) · Lecture Notes in Computer Science · doi:10.1007/978-3-642-23774-4_43 · Cited by 37 · see citing works
Treatment of claustrophobias and snake/spider phobias: fear of arousal and fear of context.
Craske, M., Mohlman, J., Yi, J. I., Glover, D. A., & Valeri, S. M. (1995) · Behaviour Research and Therapy · doi:10.1016/0005-7967(94)p4441-v · Cited by 31 · see citing works
Wrzesien, M., Bretón-López, J. M., Botella, C., Burkhardt, J., Alcañíz, M., Pérez-Ara, M. Á., & del Amo, A. R. (2013) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465813000088 · Cited by 26 · see citing works
The Scarier the Better: Maximizing Exposure Therapy Outcomes for Spider Fear
Norberg, M. M., Newins, A. R., Jiang, Y., Xu, J., Forcadell, E., Alberich, C., & Deacon, B. J. (2018) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465818000437 · Cited by 17 · see citing works
Javanbakht, A., Madaboosi, S., & Grasser, L. R. (2021) · Annals of Clinical Psychiatry · doi:10.12788/acp.0042 · Cited by 13 · see citing works
Evaluation of the quality of collaboration between the client and the therapist in phobia treatments
Wrzesien, M., Burkhardt, J., Botella, C., & Alcañíz, M. (2012) · Interacting with Computers · doi:10.1016/j.intcom.2012.09.001 · Cited by 12 · see citing works
Viña Lorenzo, C., Herrero Fernández, M., Rivero, F., Álvarez Pérez, Y., Fumero Hernández, A., Bethencourt Pérez, J. M., Pitti, C., & Peñate, W. (2020) · Revista de Neurologia · doi:10.33588/rn.7111.2019487 · Cited by 7 · see citing works
Brás, S., Soares, S. C., Cruz, T., Magalhães, T., Marques, B., Dantas, C., Fernandes, N., & Fernandes, J. M. (2018) · Brain and Behavior · doi:10.1002/brb3.1084 · Cited by 7 · see citing works
Virtual Reality Exposure Therapy of Anxiety Disorders
Wang, G., & Li, L. (2013) · Advances in Psychological Science · doi:10.3724/sp.j.1042.2012.01277 · Cited by 6 · see citing works
Virtuelle Expositionstherapie bei Angststörungen
Shiban, Y. (2018) · Der Nervenarzt · doi:10.1007/s00115-018-0596-z · Cited by 6 · see citing works
Toffolo, M. B. J., Fehribach, J. R., van Klaveren, C., Cornelisz, I., van Straten, A., van Gelder, J., & Donker, T. (2022) · PLoS ONE · doi:10.1371/journal.pone.0271175 · Cited by 6 · see citing works
Zimmer, A., Wang, N., Ibach, M., Fehlmann, B., Schicktanz, N. S., Bentz, D., Michael, T., Papassotiropoulos, A., & de Quervain, D. J. ‐. (2021) · doi:10.31219/osf.io/cjrgk · Cited by 2 · see citing works
Diffractive vs holographic vs reflective waveguides: what should the industry target?
Bouhamri, Z. (2023) · doi:10.1117/12.2651748 · Cited by 2 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- [14]Adnan NH Ahmad I Abdullasim N Systematic review on augmented reality application for autism children J Adv Res Dyn Control Syst 2018 10 11 26 32
- [24]Boland A Cherry MG Dickson R Doing a Systematic Review: A Student's Guide, 2nd Edition 2017 Los Angeles SAGE Publications
Cited by
Sorted by citations
Ong, T., Barrera, J. F., Sunkara, C., Soni, H., Ivanova, J., Cummins, M. R., Schuler, K. R., Wilczewski, H., Welch, B. M., & Bunnell, B. E. (2024) · Frontiers in Virtual Reality · doi:10.3389/frvir.2024.1332874 · Cited by 19 · see citing works
Immersive technologies for depression care: scoping review
Reategui-Rivera, C. M., Villarreal-Zegarra, D., De La Cruz-Torralva, K., Díaz-Sánchez, P., & Finkelstein, J. (2024) · JMIR Mental Health · doi:10.2196/56056 · Cited by 19 · see citing works
Mental health in the virtual world: Challenges and opportunities in the metaverse era
del Hoyo, Y. L., Elices, M., & García‐Campayo, J. (2024) · World Journal of Clinical Cases · doi:10.12998/wjcc.v12.i17.2939 · Cited by 14 · see citing works
Fradette, M.-J., Azrak, J., Cousineau, F., Désilets, M., & Dumais, A. (2025) · BioMedInformatics · doi:10.3390/biomedinformatics5030048 · Cited by 4 · see citing works
Using iVR to deliver optimal psychotherapy experience—current perspectives on VRET for acrophobia
Varšová, K. K., & Juřík, V. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1491622 · Cited by 6 · see citing works
Augmented reality as an aid to behavior therapy for anxiety disorders: A narrative review
Rajkumar, R. P. (2024) · Cureus · doi:10.7759/cureus.69454 · Cited by 3 · see citing works
Two Explorative Studies on Tangible Augmented Reality for Neurodevelopmental Disorders
Vona, F., Valcamonica, G., & Garzotto, F. (2025) · Lecture notes in computer science · doi:10.1007/978-3-031-93712-5_13 · Cited by 1 · see citing works
Yin, C., McIntosh, J., & Marques, B. (2025) · Exploration of Digital Health Technologies · doi:10.37349/edht.2025.101160 · Cited by 1 · see citing works
Mental health in the virtual world: Are we ready for the metaverse era?
Mamede, T., & Lordêlo, P. (2024) · World Journal of Methodology · doi:10.5662/wjm.v14.i4.95064 · Cited by 1 · see citing works
Augmented Reality in the Treatment of Stress and Anxiety Disorders: A Literature Synthesis
Vona, F., Kuhlencord, M., Fox, J., Kojić, T., Shiban, Y., & Voigt‐Antons, J. (2025) · ACM International Conference on Intelligent Virtual Agents (IVA) · doi:10.1145/3742886.3756697
Khomitskyi, M. Y., & Kondratenko, M. Y. (2025) · Ukrains kyi Visnyk Psykhonevrolohii · doi:10.36927/2079-0325-v33-is4-2025-11
Ardi, Z., Putra, A. H., Eseadi, C., & Sumari, M. B. (2025) · International Conference on Information, Control, and Communication Technologies (ICCT) · doi:10.1109/icct67028.2025.11427432
Trapp, W., Röder, S., & Wimmer, F. (2026) · Internet Interventions · doi:10.1016/j.invent.2026.100966
Seierstad, A., Bull, H. C., Brevik, P., Bryn, K., Yasmin, H., Løvgren, A., Røssberg, J. I., & Lystad, J. U. (2026) · Frontiers in Virtual Reality · doi:10.3389/frvir.2026.1898848
Mutluer, T., Morey, A. Ö., Karaturhan, P., Genç, H. A., Markaroğlu, R., Erbey, F., Eker, N., Küpesiz, A., Küpesiz, F. T., Guler, E., et al. (2026) · Pediatric Blood & Cancer · doi:10.1002/1545-5017.70721
- Authors
- Hasan, S., Alhaj, H., & Hassoulas, A.
- Affiliations
- Cardiff University (GB)
- University of Sharjah (AE)
- Corresponding author
- Alhaj, Hamid
- Venue
- JMIR Mental Health
- Publisher
- JMIR Publications Inc.
- Published
- 2023-11-30
- Volume
- 10
- Pages
- e51318
- ISSN
- 2368-7959 (ISSN-L)
- PMC
- PMC10722365
- OpenAlex
- W4389180384
- Cited by
- 15
- References
- 39
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 6
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- JMIR Mental Health (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- phobia, phobia treatment, therapeutic relationship, in vivo exposure therapy, treatment efficacy, cost-effectiveness, long-term treatment outcomes, adults
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review