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Effect of a High-Protein, Low-Carbohydrate Diet on Blood Glucose Control in People With Type 2 Diabetes

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Gannon, Mary C., Nuttall, Frank Q.·2004·Diabetes

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Abstract

There has been interest in the effect of various types and amounts of dietary carbohydrates and proteins on blood glucose. On the basis of our previous data, we designed a high-protein/low-carbohydrate, weight-maintaining, nonketogenic diet. Its effect on glucose control in people with untreated type 2 diabetes was determined. We refer to this as a low-biologically-available-glucose (LoBAG) diet. Eight men were studied using a randomized 5-week crossover design with a 5-week washout period. The carbohydrate:protein:fat ratio of the control diet was 55:15:30. The test diet ratio was 20:30:50. Plasma and urinary β-hydroxybutyrate were similar on both diets. The mean 24-h integrated serum glucose at the end of the control and LoBAG diets was 198 and 126 mg/dl, respectively. The percentage of glycohemoglobin was 9.8 ± 0.5 and 7.6 ± 0.3, respectively. It was still decreasing at the end of the LoBAG diet. Thus, the final calculated glycohemoglobin was estimated to be ∼6.3–5.4%. Serum insulin was decreased, and plasma glucagon was increased. Serum cholesterol was unchanged. Thus, a LoBAG diet ingested for 5 weeks dramatically reduced the circulating glucose concentration in people with untreated type 2 diabetes. Potentially, this could be a patient-empowering way to ameliorate hyperglycemia without pharmacological intervention. The long-term effects of such a diet remain to be determined.

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[Ketogenic diets: additional benefits to the weight loss and unfounded secondary effects].
Pérez-Guisado, J. (2008) · PubMed · Cited by 27
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Self-citation
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High‐protein low‐carbohydrate diets: what is the rationale?
Busetto, L., Marangon, M., & Stefano, F. D. (2011) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.1171 · Cited by 23
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Kamruzzaman, M., Horowitz, M., Jones, K. L., & Marathe, C. S. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.661877 · Cited by 23
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Scholl, J. (2012) · Cholesterol · doi:10.1155/2012/367898 · Cited by 22
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Importance of low carbohydrate diets in diabetes management
Krebs, J. D., Hall, R. M., & Parry‐Strong, A. (2016) · Nutrition and Dietary Supplements · doi:10.2147/nds.s74719 · Cited by 16
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Muntis, F. R., Smith‐Ryan, A. E., Crandell, J., Evenson, K. R., Maahs, D. M., Seid, M., Shaikh, S. R., & Mayer‐Davis, E. J. (2023) · Nutrients · doi:10.3390/nu15081981 · Cited by 18
All-cause mortality of patients with dyslipidemia up to 19 years after a multidisciplinary lifestyle modification programme: a randomized trial
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The relationship between 24-hour integrated glucose concentrations and % glycohemoglobin
Hassan, Y., Johnson, B., Nader, N., Gannon, M. C., & Nuttall, F. Q. (2006) · Journal of Laboratory and Clinical Medicine · doi:10.1016/j.lab.2005.05.009 · Cited by 15
Self-citation
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Robert, S. D., & Ismail, A. A.-S. (2011) · Annals of Nutrition and Metabolism · doi:10.1159/000335224 · Cited by 14
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Dyson, P. A., McArdle, P., Mellor, D. D., & Guess, N. D. (2018) · Diabetic Medicine · doi:10.1111/dme.13826 · Cited by 15
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Tanaka, S., Wakui, H., Azushima, K., Tsukamoto, S., Yamaji, T., Urate, S., Suzuki, T., Abe, E., Taguchi, S., Yamada, T., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097778 · Cited by 15
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Carbohydrate restriction in patients with advanced cancer: a protocol to assess safety and feasibility with an accompanying hypothesis
Fine, E. J., Segal-Isaacson, C. J., Feinman, R. D., & Sparano, J. A. (2008) · Community Oncology · doi:10.1016/s1548-5315(11)70179-6 · Cited by 13
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[EFFECT OF LOW CARBOHYDRATE DIETS ON WEIGHT LOSS AND GLYCOSILATED HEMOGLOBIN IN PEOPLE WITH TYPE 2 DIABETES: SYSTEMATIC REVIEW].
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Dietary intake in people consuming a low‐carbohydrate diet in the UK Biobank
Shafique, M., Russell, S., Murdoch, S., Bell, J. D., & Guess, N. D. (2017) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12527 · Cited by 11
High-Protein Diet Associated with Bocaiuva Supplementation Decreases Body Fat and Improves Glucose Tolerance in Resistance-Trained Rats
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Authors: Gannon, M. C., & Nuttall, F. Q.
Affiliations: University of Minnesota (US)
ORCID: Gannon, Mary C.
Venue: Diabetes
Publisher: American Diabetes Association
Published: 2004-09-01
Volume: 53
Issue: 9
Pages: 2375-2382
ISSN: 0012-1797 (ISSN-L)
1939-327X
DOI: 10.2337/diabetes.53.9.2375
OpenAlex: W2140156866
Cited by: 428
References: 29
Citations by year: 2026: 3 · 2025: 12 · 2024: 15 · 2023: 10 · 2022: 15 · 2021: 28 · 2020: 70 · 2019: 18 · 2018: 23 · 2017: 20 · 2016: 13 · 2015: 18 · 2014: 12 · 2013: 19 · 2012: 24
FWCI: 9.46
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Diabetes (publishedVersion)
PubMed (publishedVersion)
Funders: American Diabetes Association
Topics: Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
Keywords: type 2 diabetes, high-protein low-carbohydrate diet, glycemic control, glycohemoglobin, serum insulin, plasma glucagon, beta-hydroxybutyrate, ketosis, hyperglycemia, dietary intervention
MeSH terms: Aged, Aged, 80 and over, Blood Glucose, Body Weight, Diabetes Mellitus, Type 2, Dietary Carbohydrates, Dietary Proteins, Glycated Hemoglobin, Humans, Ketones, Male, Middle Aged, Cross-Over Studies, 3-Hydroxybutyric Acid

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Effect of a High-Protein, Low-Carbohydrate Diet on Blood Glucose Control in People With Type 2 Diabetes

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