Host specificity of the ruminal bacterial community in the dairy cow following near-total exchange of ruminal contents

Weimer, P.J.; Stevenson, D.M.; Mantovani, H.C.; Man, S.L.C.

doi:10.3168/jds.2010-3500

Cited by 274Ruminant Nutrition and Digestive PhysiologyGut microbiota and healthAnaerobic Digestion and Biogas Production

Host specificity of the ruminal bacterial community in the dairy cow following near-total exchange of ruminal contents

Open access

Weimer, P.J., Stevenson, D.M., Mantovani, H.C., Man, S.L.C.·2010·Journal of Dairy Science

DOI 10.3168/jds.2010-3500

Open this paper in CoChat — free account Open PDF

Abstract

The purpose of this study was to examine the stability and host specificity of a cow's ruminal bacterial community following massive challenge with ruminal microflora from another cow. In each of 2 experiments, 1 pair of cows was selected on the basis of differences in ruminal bacterial community composition (BCC), determined by automated ribosomal intergenic spacer analysis (ARISA), a culture-independent "community fingerprinting" technique. Each pair of cows was then subjected to a 1-time exchange of >95% of ruminal contents without changing the composition of a corn silage/alfalfa haylage-based TMR. In experiment 1, the 2 cows differed (P<0.01) in prefeed ruminal pH (mean = 6.88 vs. 6.14) and prefeed total VFA concentration (mean = 57 vs. 77 mM), averaged over 3 d. Following exchange of ruminal contents, ruminal pH and total VFA concentration in both cows returned to their preexchange values within 24h. Ruminal BCC also returned to near its original profile, but this change required 14 d for 1 cow and 61 d for the other cow. In experiment 2, the 2 other cows differed in prefeed ruminal pH (mean = 6.69 vs. 6.20) and total VFA concentration (mean = 101 vs. 136 mM). Following exchange of ruminal contents, the first cow returned to its preexchange pH and VFA values within 24h; the second cow's rumen rapidly stabilized to a higher prefeed pH (mean = 6.47) and lower prefeed VFA concentration (mean = 120 mM) that was retained over the 62-d test period. Both cows reached somewhat different BCC than before the exchange. However, the BCC of both cows remained distinct and were ultimately more similar to that of the preexchange BCC than of the donor animal BCC. The data indicate that the host animal can quickly reestablish its characteristic ruminal pH and VFA concentration despite dramatic perturbation of its ruminal microbial community. The data also suggest that ruminal BCC displays substantial host specificity that can reestablish itself with varying success when challenged with a microbial community optimally adapted to ruminal conditions of a different host animal.

Integrity signals

Registry

Crossref · 10.3168/jds.2010-3500

Cites

23 of 23 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

After near total exchange of the rumen contents between cows, individuals restored their bacterial composition back to pre-exchange conditions, which also returned rumen pH and volatile fatty acid (VFA) concentration to pre-exchange values.
“Evidence of the influence of the host on the rumen microbiome was first postulated by Weimer et al. (2010) who found that after near total exchange of the rumen contents between cows, individuals restored their bacterial composition back to pre-exchange conditions, which also returned rumen pH and volatile fatty acid (VFA) concentration to pre-exchange values.”
From Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future (2018) · cites this paper as Weimer et al., 2010

Non‐parametric multivariate analyses of changes in community structure
Clarke, K. R. (1993) · Australian Journal of Ecology · doi:10.1111/j.1442-9993.1993.tb00438.x · Cited by 14,196 · see citing works
Resistance, resilience, and redundancy in microbial communities
Allison, S., & Martiny, J. B. H. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801925105 · Cited by 3,181 · see citing works
The Rumen and Its Microbes
Hungate, R. E. (2013) · Elsevier eBooks · doi:10.1016/c2013-0-12555-x · Cited by 3,060 · see citing works
Automated Approach for Ribosomal Intergenic Spacer Analysis of Microbial Diversity and Its Application to Freshwater Bacterial Communities
Fisher, M. M., & Triplett, E. W. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.10.4630-4636.1999 · Cited by 843 · see citing works
Dominance of Prevotella and low abundance of classical ruminal bacterial species in the bovine rumen revealed by relative quantification real-time PCR
Stevenson, D. M., & Weimer, P. J. (2007) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-006-0802-y · Cited by 833 · see citing works
Measuring the Inertia and Resilience of Ecosystems
Westman, W. E. (1978) · BioScience · doi:10.2307/1307321 · Cited by 324 · see citing works
Coupling 16S‐ITS rDNA clone libraries and automated ribosomal intergenic spacer analysis to show marine microbial diversity: development and application to a time series
Brown, M. V., Schwalbach, M. S., Hewson, I., & Fuhrman, J. A. (2005) · Environmental Microbiology · doi:10.1111/j.1462-2920.2005.00835.x · Cited by 255 · see citing works
Successful transfer of DHP‐degrading bacteria from Hawaiian goats to Australian ruminants to overcome the toxicity of Leucaena
Jones, R. J., & Megarrity, R. (1986) · Australian Veterinary Journal · doi:10.1111/j.1751-0813.1986.tb02990.x · Cited by 230 · see citing works
Epithelial Capacity for Apical Uptake of Short Chain Fatty Acids Is a Key Determinant for Intraruminal pH and the Susceptibility to Subacute Ruminal Acidosis in Sheep ,
Penner Gregory, B., Aschenbach, J. R., Gäbel, G., Rackwitz, R., & Oba, M. (2009) · Journal of Nutrition · doi:10.3945/jn.109.108506 · Cited by 207 · see citing works
Manipulating ruminal fermentation: a microbial ecological perspective.
Weimer, P. J. (1998) · Journal of Animal Science · doi:10.2527/1998.76123114x · Cited by 172 · see citing works
The influence of habitat heterogeneity on freshwater bacterial community composition and dynamics
Shade, A. L., Jones, S. E., & McMahon, K. D. (2008) · Environmental Microbiology · doi:10.1111/j.1462-2920.2007.01527.x · Cited by 157 · see citing works
ARISA analysis of ruminal bacterial community dynamics in lactating dairy cows during the feeding cycle
Welkie, D. G., Stevenson, D. M., & Weimer, P. J. (2009) · Anaerobe · doi:10.1016/j.anaerobe.2009.07.002 · Cited by 137 · see citing works
Shifts in bacterial community composition in the rumen of lactating dairy cows under milk fat-depressing conditions
Weimer, P. J., Stevenson, D. M., & Mertens, D. R. (2010) · Journal of Dairy Science · doi:10.3168/jds.2009-2206 · Cited by 113 · see citing works
A segmented gas/liquid delivery system for continuous culture of microorganisms on insoluble substrates and its use for growth of Ruminococcus flavefaciens on cellulose
Weimer, P. J., Shi, Y., & Odt, C. L. (1991) · Applied Microbiology and Biotechnology · doi:10.1007/bf00164416 · Cited by 108 · see citing works
Genetically Modified Ruminal Bacteria Protect Sheep from Fluoroacetate Poisoning
Gregg, K., Hamdorf, B. J., Henderson, K., Kopečný, J., & Wong, C. M. (1998) · Applied and Environmental Microbiology · doi:10.1128/aem.64.9.3496-3498.1998 · Cited by 108 · see citing works
How Many Ruminal Bacteria Are There?
Krause, D. O., & Russell, J. B. (1996) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(96)76506-2 · Cited by 99 · see citing works
Effect of administration of an anaerobic gut fungus isolated from wild blue bull (Boselaphus tragocamelus) to buffaloes (Bubalus bubalis) on in vivo ruminal fermentation and digestion of nutrients
Paul, S. S., Kamra, D. N., Sastry, V. R. B., Sahu, N. P., & Agarwal, N. (2004) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2004.01.010 · Cited by 50 · see citing works
Use of 16S-rRNA Based Techniques to Investigate the Ecological Succession of Microbial Populations in the Immature Lamb Rumen: Tracking of a Specific Strain of Inoculated Ruminococcus and Interactions with Other Microbial Populations in Vivo
Krause, D. O., Smith, W. J. M., Ryan, F. M. E., Mackie, R. I., & McSweeney, C. S. (1999) · Microbial Ecology · doi:10.1007/s002489901006 · Cited by 44 · see citing works
Repeated ruminal dosing of Ruminococcus flavefaciens NJ along with a probiotic mixture in forage or concentrate-fed dairy cows: Effect on ruminal fermentation, cellulolytic populations and in sacco digestibility
Chiquette, J., Talbot, G., Markwell, F., Nili, N., & Forster, R. J. (2007) · Canadian Journal of Animal Science · doi:10.4141/a06-066 · Cited by 37 · see citing works
Addition of cellulolytic clostridia to the bovine rumen and pig intestinal tract
Varel, V. H., Yen, J. T., & Kreikemeier, K. K. (1995) · Applied and Environmental Microbiology · doi:10.1128/aem.61.3.1116-1119.1995 · Cited by 32 · see citing works
Effects of animal-to-animal exchange of ruminal contents on the feed intake and ruminal characteristics of fed and fasted lambs.
Cole, N. A. (1991) · Journal of Animal Science · doi:10.2527/1991.6941795x · Cited by 26 · see citing works
Effect of Abrupt Ration Changes on Milk and Blood Components
Satter, L. D., & Bringe, A. N. (1969) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(69)86840-2 · Cited by 23 · see citing works
Analysis of methanogens in the bovine rumen by polymerase chain reaction single‐strand conformation polymorphism
TATSUOKA, N., Mohammed, N., Mitsumori, M., Tajima, K., Hara, K., KURIHARA, M., & ITABASHI, H. (2007) · Animal Science Journal · doi:10.1111/j.1740-0929.2007.00470.x · Cited by 10 · see citing works

Flagged first, then by citations

Sorted by citations

Redundancy, resilience, and host specificity of the ruminal microbiota: implications for engineering improved ruminal fermentations
Weimer, P. J. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00296 · Cited by 487 · see citing works
Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future
Huws, S. A., Creevey, C. J., Oyama, L. B., Mizrahi, I., Denman, S. E., Popova, M., Muñoz-Tamayo, R., Forano, E., Waters, S. M., Hess, M., et al. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02161 · Cited by 487 · see citing works
Self-citation
Characterization of the Core Rumen Microbiome in Cattle during Transition from Forage to Concentrate as Well as during and after an Acidotic Challenge
Petri, R. M., Schwaiger, T., Penner, G. B., Beauchemin, K. A., Forster, R. J., McKinnon, J. J., & McAllister, T. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083424 · Cited by 410 · see citing works
Rumen Microbiome from Steers Differing in Feed Efficiency
Myer, P. R., Smith, T. P. L., Wells, J. E., Kuehn, L. A., & Freetly, H. C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129174 · Cited by 413 · see citing works
The ruminal microbiome associated with methane emissions from ruminant livestock
Tapio, I., Snelling, T. J., Strozzi, F., & Wallace, R. J. (2017) · Journal of Animal Science and Biotechnology · doi:10.1186/s40104-017-0141-0 · Cited by 391 · see citing works
Host genetics and the rumen microbiome jointly associate with methane emissions in dairy cows
Difford, G. F., Plichta, D. R., Løvendahl, P., Lassen, J., Noel, S. J., Højberg, O., Wright, A. G., Zhu, Z., Kristensen, L., Nielsen, H. B., et al. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007580 · Cited by 387 · see citing works
Invited review: Transitioning from milk to solid feed in dairy heifers
Khan, M. A., Bach, À., Weary, D. M., & von Keyserlingk, M. A. G. (2015) · Journal of Dairy Science · doi:10.3168/jds.2015-9975 · Cited by 384 · see citing works
Manipulating rumen microbiome and fermentation through interventions during early life: a review
Yáñez-Ruiz, D. R., Abecia, L., & Newbold, C. J. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01133 · Cited by 336 · see citing works
Invited Review: Nitrogen in Ruminant Nutrition: A Review of Measurement Techniques
Hristov, A. N., Bannink, A., Crompton, L. A., Huhtanen, P., Kreuzer, M., McGee, M., Nozière, P., Reynolds, C. K., Bayat, A. R., Yáñez-Ruiz, D. R., et al. (2019) · Journal of Dairy Science · doi:10.3168/jds.2018-15829 · Cited by 283 · see citing works
Prevotella: A Key Player in Ruminal Metabolism
Betancur-Murillo, C. L., Aguilar-Marín, S. B., & Jovel, J. (2022) · Microorganisms · doi:10.3390/microorganisms11010001 · Cited by 283 · see citing works
Dynamic Alterations in Yak Rumen Bacteria Community and Metabolome Characteristics in Response to Feed Type
Liu, C., Wu, H., Liu, S., Chai, S., Meng, Q., & Zhou, Z. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01116 · Cited by 250 · see citing works
High-throughput Methods Redefine the Rumen Microbiome and Its Relationship with Nutrition and Metabolism
McCann, J. C., Wickersham, T. A., & Loor, J. J. (2014) · Bioinformatics and Biology Insights · doi:10.4137/bbi.s15389 · Cited by 227 · see citing works
Ruminal methane production: Associated microorganisms and the potential of applying hydrogen-utilizing bacteria for mitigation
Lan, W., & Yang, C. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.11.180 · Cited by 211 · see citing works
Microbial succession in the gastrointestinal tract of dairy cows from 2 weeks to first lactation
Dill‐McFarland, K. A., Breaker, J. D., & Suen, G. (2017) · Scientific Reports · doi:10.1038/srep40864 · Cited by 207 · see citing works
Understanding host-microbial interactions in rumen: searching the best opportunity for microbiota manipulation
Malmuthuge, N., & Guan, L. L. (2017) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-016-0135-3 · Cited by 204 · see citing works
Harnessing the genetics of the modern dairy cow to continue improvements in feed efficiency
VandeHaar, M. J., Armentano, L. E., WEIGEL, K. A., Spurlock, D. M., Tempelman, R. J., & Veerkamp, R. F. (2016) · Journal of Dairy Science · doi:10.3168/jds.2015-10352 · Cited by 200 · see citing works
Rumen Bacterial Community Composition in Holstein and Jersey Cows Is Different under Same Dietary Condition and Is Not Affected by Sampling Method
Paz, H. A., Anderson, C. L., Muller, M. J., Kononoff, P. J., & Fernando, S. C. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01206 · Cited by 197 · see citing works
Age-related differences in the cloacal microbiota of a wild bird species
van Dongen, W. F. D., White, J., Brandl, H. B., Moodley, Y., Merkling, T., Leclaire, S., Blanchard, P., Danchin, É., Hatch, S. A., & Wagner, R. H. (2013) · BMC Ecology · doi:10.1186/1472-6785-13-11 · Cited by 180 · see citing works
Biogeographical differences in the influence of maternal microbial sources on the early successional development of the bovine neonatal gastrointestinal tract
Yeoman, C. J., Ishaq, S. L., Bichi, E., Olivo, S. K., Lowe, J., & Aldridge, B. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-21440-8 · Cited by 168 · see citing works
Review: Selecting for improved feed efficiency and reduced methane emissions in dairy cattle
Løvendahl, P., Difford, G. F., Li, B., Chagunda, M. G. G., Huhtanen, P. J., Lidauer, M., Lassen, J., & Lund, P. (2018) · animal · doi:10.1017/s1751731118002276 · Cited by 157 · see citing works
Nutritional management of the transition cow in the 21st century – a paradigm shift in thinking
Roche, J. R., Bell, A. W., Overton, T. R., & Loor, J. J. (2013) · Animal Production Science · doi:10.1071/an12293 · Cited by 153 · see citing works
The players may change but the game remains: network analyses of ruminal microbiomes suggest taxonomic differences mask functional similarity
Taxis, T. M., Wolff, S., Gregg, S. J., Minton, N. O., Zhang, C., Dai, J., Schnabel, R. D., Taylor, J. F., Kerley, M. S., Pires, J. C., et al. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv973 · Cited by 146 · see citing works
Review: The compositional variation of the rumen microbiome and its effect on host performance and methane emission
Mizrahi, I., & Jami, E. (2018) · animal · doi:10.1017/s1751731118001957 · Cited by 147 · see citing works
Strategies to improve the efficiency of beef cattle production
Terry, S. A., Basarab, J. A., Guan, L. L., & McAllister, T. A. (2021) · Canadian Journal of Animal Science · doi:10.1139/cjas-2020-0022 · Cited by 142 · see citing works
“For example, total rumen transfaunation did not permanently alter the microbiome, with it returning to its original state in some individuals within 7 d (Weimer et al. 2010; Zhou et al. 2018).”
Background
Nitrogen metabolism and rumen microbial enumeration in lactating cows with divergent residual feed intake fed high-digestibility pasture
Ríus, A. G., Kittelmann, S., Macdonald, K. A., Waghorn, G. C., Janssen, P. H., & Sikkema, E. (2012) · Journal of Dairy Science · doi:10.3168/jds.2012-5392 · Cited by 141 · see citing works
Rumen transfaunation
DePeters, E. J., & George, L. W. (2014) · Immunology Letters · doi:10.1016/j.imlet.2014.05.009 · Cited by 141 · see citing works
A Comparative Review on Microbiota Manipulation: Lessons From Fish, Plants, Livestock, and Human Research
Brugman, S., Ikeda‐Ohtsubo, W., Braber, S., Folkerts, G., Pieterse, C. M. J., & Bakker, P. A. H. M. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2018.00080 · Cited by 127 · see citing works
Engineering the microbiome for animal health and conservation
Song, S. J., Woodhams, D. C., Martino, C., Allaband, C., Mu, A., Javorschi-Miller-Montgomery, S., Suchodolski, J. S., & Knight, R. D. (2019) · Experimental Biology and Medicine · doi:10.1177/1535370219830075 · Cited by 127 · see citing works
Altering the Gut Microbiome of Cattle: Considerations of Host-Microbiome Interactions for Persistent Microbiome Manipulation
Clemmons, B. A., Voy, B. H., & Myer, P. R. (2018) · Microbial Ecology · doi:10.1007/s00248-018-1234-9 · Cited by 124 · see citing works
Invited review: Phenotypes to genetically reduce greenhouse gas emissions in dairying
de Haas, Y., Pszczoła, M., Soyeurt, H., Wall, E., & Lassen, J. (2016) · Journal of Dairy Science · doi:10.3168/jds.2016-11246 · Cited by 122 · see citing works
Assessment of microbiome changes after rumen transfaunation: implications on improving feed efficiency in beef cattle
Zhou, M., Peng, Y., Chen, Y., Klinger, C. M., Oba, M., Liu, J., & Guan, L. L. (2018) · Microbiome · doi:10.1186/s40168-018-0447-y · Cited by 115 · see citing works
Perturbation Dynamics of the Rumen Microbiota in Response to Exogenous Butyrate
Li, R. W., Wu, S., Baldwin, R. L., Li, W., & Li, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029392 · Cited by 114 · see citing works
Relationship between the Rumen Microbiome and Residual Feed Intake-Efficiency of Brahman Bulls Stocked on Bermudagrass Pastures
McCann, J. C., Wiley, L. M., Forbes, T. D. A., Rouquette, F. M., Jr., & Tedeschi, L. O. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091864 · Cited by 113 · see citing works
Hydrogen and methane emissions from beef cattle and their rumen microbial community vary with diet, time after feeding and genotype
Rooke, J. A., Wallace, R. J., Duthie, C.-A., McKain, N., de Souza, S. M., Hyslop, J. J., Ross, D. W., Waterhouse, A., & Roehe, R. (2014) · British Journal Of Nutrition · doi:10.1017/s0007114514000932 · Cited by 112 · see citing works
Evaluation of the length of adaptation period for changeover and crossover nutritional experiments with cattle fed tropical forage-based diets
Machado, M. G., Detmann, E., Mantovani, H. C., Filho, S. D. C. V., Bento, C. B. P., Marcondes, M. I., & Assunção, A. D. S. (2016) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2016.10.009 · Cited by 111 · see citing works
RUMINANT NUTRITION SYMPOSIUM: How to use data on the rumen microbiome to improve our understanding of ruminant nutrition1,2
Firkins, J. L., & Yu, Z. (2015) · Journal of Animal Science · doi:10.2527/jas.2014-8754 · Cited by 110 · see citing works
Bovine host genome acts on rumen microbiome function linked to methane emissions
Martínez-Álvaro, M., Auffret, M. D., Duthie, C.-A., Dewhurst, R. J., Cleveland, M. A., Watson, M., & Roehe, R. (2022) · Communications Biology · doi:10.1038/s42003-022-03293-0 · Cited by 113 · see citing works
Symposium review: Host–rumen microbe interactions may be leveraged to improve the productivity of dairy cows
Bickhart, D. M., & Weimer, P. J. (2017) · Journal of Dairy Science · doi:10.3168/jds.2017-13328 · Cited by 105 · see citing works
Dynamic progression of the calf’s microbiome and its influence on host health
Amin, N., & Seifert, J. (2021) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2021.01.035 · Cited by 102 · see citing works
Gut Microbiota Implications for Health and Welfare in Farm Animals: A Review
Chen, S., Luo, S., & Yan, C. (2021) · Animals · doi:10.3390/ani12010093 · Cited by 106 · see citing works
Diet Influences Early Microbiota Development in Dairy Calves without Long-Term Impacts on Milk Production
Dill‐McFarland, K. A., Weimer, P. J., Breaker, J. D., & Suen, G. (2018) · Applied and Environmental Microbiology · doi:10.1128/aem.02141-18 · Cited by 101 · see citing works
Archaeal abundance in post-mortem ruminal digesta may help predict methane emissions from beef cattle
Wallace, R. J., Rooke, J. A., Duthie, C.-A., Hyslop, J. J., Ross, D. W., McKain, N., de Souza, S. M., Snelling, T. J., Waterhouse, A., & Roehe, R. (2014) · Scientific Reports · doi:10.1038/srep05892 · Cited by 100 · see citing works
Heat Stress: Effects on Rumen Microbes and Host Physiology, and Strategies to Alleviate the Negative Impacts on Lactating Dairy Cows
Kim, S., Ramos, S., Valencia, R. A., Cho, Y.-I., & Lee, S. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.804562 · Cited by 114 · see citing works
Rumen bacterial communities shift across a lactation in Holstein, Jersey and Holstein × Jersey dairy cows and correlate to rumen function, bacterial fatty acid composition and production parameters
Bainbridge, M. L., Cersosimo, L. M., Wright, A. G., & Kraft, J. (2016) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiw059 · Cited by 96 · see citing works
Ruminal Fermentation
Owens, F. N., & Başalan, M. (2016) · Springer eBooks · doi:10.1007/978-3-319-30533-2_3 · Cited by 88 · see citing works
Transient changes in milk production efficiency and bacterial community composition resulting from near-total exchange of ruminal contents between high- and low-efficiency Holstein cows
Weimer, P. J., Cox, M. S., Vieira de Paula, T., Lin, M., Hall, M. B., & Suen, G. (2017) · Journal of Dairy Science · doi:10.3168/jds.2017-12746 · Cited by 86 · see citing works
Self-citation
Tiny but mighty: The role of the rumen microbes in livestock production
Cammack, K. M., Austin, K. J., Lamberson, W. R., Conant, G. C., & Cunningham-Hollinger, H. C. (2018) · Journal of Animal Science · doi:10.1093/jas/skx053 · Cited by 85 · see citing works
Use of Yeast Probiotics in Ruminants: Effects and Mechanisms of Action on Rumen pH, Fibre Degradation, and Microbiota According to the Diet
Chaucheyras‐Durand, F., Chevaux, E., Martin, C., & Forano, É. (2012) · InTech eBooks · doi:10.5772/50192 · Cited by 90 · see citing works
The Role of Innate Immune Response and Microbiome in Resilience of Dairy Cattle to Disease: The Mastitis Model
Bronzo, V., Lopreiato, V., Riva, F., Amadori, M., Curone, G., Addis, M. F., Cremonesi, P., Moroni, P., Trevisi, E., & Castiglioni, B. (2020) · Animals · doi:10.3390/ani10081397 · Cited by 83 · see citing works
Repeated inoculation of cattle rumen with bison rumen contents alters the rumen microbiome and improves nitrogen digestibility in cattle
Ribeiro, G. O., Oss, D. B., He, Z., Gruninger, R. J., Elekwachi, C. O., Forster, R. J., Yang, W. Z., Beauchemin, K. A., & McAllister, T. A. (2017) · Scientific Reports · doi:10.1038/s41598-017-01269-3 · Cited by 80 · see citing works
Impact of the rumen microbiome on milk fatty acid composition of Holstein cattle
Buitenhuis, B., Lassen, J., Noel, S. J., Plichta, D. R., Sørensen, P. B., Difford, G. F., & Poulsen, N. A. (2019) · Genetics Selection Evolution · doi:10.1186/s12711-019-0464-8 · Cited by 80 · see citing works
Early life dietary intervention in dairy calves results in a long-term reduction in methane emissions
Meale, S. J., Popova, M., Saro, C., Martin, C., Bernard, A., Lagrée, M., Yáñez-Ruíz, D. R., Boudra, H., Duval, S. M., & Morgavi, D. P. (2021) · Scientific Reports · doi:10.1038/s41598-021-82084-9 · Cited by 78 · see citing works
Possibilities and limits for using the gut microbiome to improve captive animal health
Diaz, J., & Reese, A. T. (2021) · Animal Microbiome · doi:10.1186/s42523-021-00155-8 · Cited by 77 · see citing works
Analysis of rumen microbial populations in lactating dairy cattle fed diets varying in carbohydrate profiles and Saccharomyces cerevisiae fermentation product
Mullins, C. R., Mamedova, L. K., Carpenter, A. J., Ying, Y., Allen, M. S., Yoon, I., & Bradford, B. J. (2013) · Journal of Dairy Science · doi:10.3168/jds.2013-6775 · Cited by 75 · see citing works
Effect of progressive inoculation of fauna-free sheep with holotrich protozoa and total-fauna on rumen fermentation, microbial diversity and methane emissions
Belanche, A., de la Fuente, G., & Newbold, C. J. (2014) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiu026 · Cited by 74 · see citing works
Alterations in ruminal bacterial populations at induction and recovery from diet-induced milk fat depression in dairy cows
Pitta, D. W., Indugu, N., Vecchiarelli, B., Rico, D. E., & Harvatine, K. J. (2018) · Journal of Dairy Science · doi:10.3168/jds.2016-12514 · Cited by 73 · see citing works
Analysis of the gut bacterial communities in beef cattle and their association with feed intake, growth, and efficiency1,2,3
Myer, P. R., Freetly, H. C., Wells, J. E., Smith, T. P. L., & Kuehn, L. A. (2017) · Journal of Animal Science · doi:10.2527/jas.2016.1059 · Cited by 73 · see citing works
Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminants
Zhang, Y., Choi, S. H., Nogoy, K. M. C., & Liang, S. (2021) · animal · doi:10.1016/j.animal.2021.100316 · Cited by 72 · see citing works
Between-cow variation in digestion and rumen fermentation variables associated with methane production
Cabezas-Garcia, E. H., Krizsan, S. J., Shingfield, K. J., & Huhtanen, P. J. (2017) · Journal of Dairy Science · doi:10.3168/jds.2016-12206 · Cited by 72 · see citing works
Investigating the effect of two methane-mitigating diets on the rumen microbiome using massively parallel sequencing
Ross, E. M., Moate, P. J., Marett, L. C., Cocks, B., & Hayes, B. J. (2013) · Journal of Dairy Science · doi:10.3168/jds.2013-6766 · Cited by 69 · see citing works
Linking Peripartal Dynamics of Ruminal Microbiota to Dietary Changes and Production Parameters
Derakhshani, H., Tun, H. M., Cardoso, F. C., Plaizier, J. C., Khafipour, E., & Loor, J. J. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.02143 · Cited by 69 · see citing works
Rumen and Fecal Microbial Community Structure of Holstein and Jersey Dairy Cows as Affected by Breed, Diet, and Residual Feed Intake
Noel, S. J., Olijhoek, D., Mclean, F., Løvendahl, P., Lund, P., & Højberg, O. (2019) · Animals · doi:10.3390/ani9080498 · Cited by 70 · see citing works
Mining the rumen for fibrolytic feed enzymes
Ribeiro, G. O., Gruninger, R. J., Badhan, A., & McAllister, T. A. (2016) · Animal Frontiers · doi:10.2527/af.2016-0019 · Cited by 68 · see citing works
Microbial community profiles of the colon from steers differing in feed efficiency
Myer, P. R., Wells, J. E., Smith, T. P. L., Kuehn, L. A., & Freetly, H. C. (2015) · SpringerPlus · doi:10.1186/s40064-015-1201-6 · Cited by 67 · see citing works
Biotechnological utilization of animal gut microbiota for valorization of lignocellulosic biomass
Ozbayram, E. G., Kleinsteuber, S., & Nikolausz, M. (2019) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-019-10239-w · Cited by 66 · see citing works
Cattle's variation in rumen ecology and metabolism and its contributions to feed efficiency
Khiaosa‐ard, R., & Zebeli, Q. (2014) · Livestock Science · doi:10.1016/j.livsci.2014.01.005 · Cited by 61 · see citing works
Linseed Oil Supplementation of Lambs’ Diet in Early Life Leads to Persistent Changes in Rumen Microbiome Structure
Lyons, T., Boland, T. M., Storey, S., & Doyle, E. M. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01656 · Cited by 60 · see citing works
Effects of partial mixed rations and supplement amounts on milk production and composition, ruminal fermentation, bacterial communities, and ruminal acidosis
Golder, H. M., Denman, S. E., McSweeney, C. S., Wales, W. J., Auldist, M. J., Wright, M. M., Marett, L. C., Greenwood, J. S., Hannah, M. C., Celi, P., et al. (2014) · Journal of Dairy Science · doi:10.3168/jds.2014-8049 · Cited by 60 · see citing works
Epimural bacterial community structure in the rumen of Holstein cows with different responses to a long-term subacute ruminal acidosis diet challenge
Wetzels, S. U., Mann, E., Pourazad, P., Qumar, M., Pinior, B., Metzler-Zebeli, B. U., Wagner, M., Schmitz‐Esser, S., & Zebeli, Q. (2016) · Journal of Dairy Science · doi:10.3168/jds.2016-11620 · Cited by 60 · see citing works
Dynamic changes in rumen fermentation and bacterial community following rumen fluid transplantation in a sheep model of rumen acidosis: implications for rumen health in ruminants
Liu, J., Li, H., Zhu, W., & Mao, S. (2019) · The FASEB Journal · doi:10.1096/fj.201802456r · Cited by 59 · see citing works
Ruminal bacterial community shifts in grain-, sugar-, and histidine-challenged dairy heifers
Golder, H. M., Denman, S. E., McSweeney, C. S., Celi, P., & Lean, I. J. (2014) · Journal of Dairy Science · doi:10.3168/jds.2014-8003 · Cited by 58 · see citing works
Limits to Dihydrogen Incorporation into Electron Sinks Alternative to Methanogenesis in Ruminal Fermentation
Ungerfeld, E. M. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01272 · Cited by 58 · see citing works
Review: Comparative methane production in mammalian herbivores
Clauß, M., Dittmann, M. T., Vendl, C., Hagen, K. B., Frei, S., Ortmann, S., Müller, D. W. H., Hammer, S., Munn, A. J., Schwarm, A., et al. (2020) · animal · doi:10.1017/s1751731119003161 · Cited by 57 · see citing works
Repeated inoculation with fresh rumen fluid before or during weaning modulates the microbiota composition and co-occurrence of the rumen and colon of lambs
Yu, S., Zhang, G., Liu, Z., Wu, P., Yu, Z., & Wang, J. (2020) · BMC Microbiology · doi:10.1186/s12866-020-1716-z · Cited by 56 · see citing works
Concepts and Consequences of a Core Gut Microbiota for Animal Growth and Development
Perlman, D., Martínez-Álvaro, M., Moraïs, S., Altshuler, I., Hagen, L. H., Jami, E., Roehe, R., Pope, P. B., & Mizrahi, I. (2021) · Annual Review of Animal Biosciences · doi:10.1146/annurev-animal-013020-020412 · Cited by 56 · see citing works
Individual animal variability in ruminal bacterial communities and ruminal acidosis in primiparous Holstein cows during the periparturient period
Mohammed, R., Stevenson, D. M., Weimer, P. J., Penner, G. B., & Beauchemin, K. A. (2012) · Journal of Dairy Science · doi:10.3168/jds.2012-5772 · Cited by 55 · see citing works
The Development of Microbiota and Metabolome in Small Intestine of Sika Deer (Cervus nippon) from Birth to Weaning
Li, Z., Wang, X., Zhang, T., Si, H., Nan, W., Xu, C., Guan, L. L., Wright, A. G., & Li, G. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00004 · Cited by 54 · see citing works
Investigating temporal microbial dynamics in the rumen of beef calves raised on two farms during early life
O’Hara, E., Kenny, D. A., McGovern, E., Byrne, C. J., McCabe, M. S., Guan, L. L., & Waters, S. M. (2020) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiz203 · Cited by 54 · see citing works
Genetic mechanisms underlying feed utilization and implementation of genomic selection for improved feed efficiency in dairy cattle
Brito, L. F., Oliveira, H. R., Houlahan, K., Fonseca, P. A. S., Lam, S., Butty, A. M., Seymour, D. J., Vargas, G., Chud, T. C. S., Silva, F. F., et al. (2020) · Canadian Journal of Animal Science · doi:10.1139/cjas-2019-0193 · Cited by 53 · see citing works
Invited review: Ruminal acidosis and its definition—A critical review
Golder, H. M., & Lean, I. J. (2024) · Journal of Dairy Science · doi:10.3168/jds.2024-24817 · Cited by 61 · see citing works
Feed additives for methane mitigation: Recommendations for testing enteric methane-mitigating feed additives in ruminant studies
Hristov, A. N., Bannink, A., Battelli, M., Belanche, A., Sanz, M. C. C., Fernández-Turren, G., García, F. J. G., Jonker, A., Kenny, D. A., Lind, V., et al. (2024) · Journal of Dairy Science · doi:10.3168/jds.2024-25050 · Cited by 52 · see citing works
Cecum microbial communities from steers differing in feed efficiency1,2,3
Myer, P. R., Wells, J. E., Smith, T. P. L., Kuehn, L. A., & Freetly, H. C. (2015) · Journal of Animal Science · doi:10.2527/jas.2015-9415 · Cited by 51 · see citing works
Diet shifts provoke complex and variable changes in the metabolic networks of the ruminal microbiome
Wolff, S., Ellison, M. J., Hao, Y., Cockrum, R., Austin, K. J., Baraboo, M., Burch, K., Lee, H. J., Maurer, T. M., Patil, R., et al. (2017) · Microbiome · doi:10.1186/s40168-017-0274-6 · Cited by 51 · see citing works
Short communication: Signs of host genetic regulation in the microbiome composition in 2 dairy breeds: Holstein and Brown Swiss
González-Recio, Ó., Zubiría, I., García-Rodríguez, A., Hurtado, A., & Atxaerandio, R. (2017) · Journal of Dairy Science · doi:10.3168/jds.2017-13179 · Cited by 50 · see citing works
Microbial community profiles of the jejunum from steers differing in feed efficiency.
Myer, P., Wells, J., Smith, T. P. L., Kuehn, L., & Freetly, H. (2016) · Journal of Animal Science · doi:10.2527/jas.2015-9839 · Cited by 40 · see citing works
Variations in methane yield and microbial community profiles in the rumen of dairy cows as they pass through stages of first lactation
Lyons, T., Bielak, A., Doyle, E. M., & Kuhla, B. (2018) · Journal of Dairy Science · doi:10.3168/jds.2017-14200 · Cited by 49 · see citing works
Feeding, Evaluating, and Controlling Rumen Function
Lean, I. J., Golder, H. M., & Hall, M. B. (2014) · Veterinary Clinics of North America Food Animal Practice · doi:10.1016/j.cvfa.2014.07.003 · Cited by 51 · see citing works
Ecological Restoration of Antibiotic-Disturbed Gastrointestinal Microbiota in Foregut and Hindgut of Cows
Ji, S., Jiang, T., Yan, H., Guo, C., Liu, J., Su, H., Alugongo, G. M., Shi, H., Wang, Y., Cao, Z., et al. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00079 · Cited by 48 · see citing works
Differential Dynamics of the Ruminal Microbiome of Jersey Cows in a Heat Stress Environment
Kim, D. H., Kim, M., Kim, S. B., Son, J.-K., Lee, J., Joo, S.-S., Gu, B., Park, T., Park, B.-Y., & Kim, E. T. (2020) · Animals · doi:10.3390/ani10071127 · Cited by 47 · see citing works
Changes in the Rumen Microbiota of Cows in Response to Dietary Supplementation with Nitrate, Linseed, and Saponin Alone or in Combination
Popova, M., Guyader, J., Silberberg, M., Seradj, A. R., Saro, C., Bernard, A., Gérard, C., Martin, C., & Morgavi, D. P. (2018) · Applied and Environmental Microbiology · doi:10.1128/aem.02657-18 · Cited by 45 · see citing works
Effects of clay mineral supplementation on particle-associated and epimural microbiota, and gene expression in the rumen of cows fed high-concentrate diet
Neubauer, V., Humer, E. C., Mann, E., Kröger, I., Reisinger, N., Wagner, M., Zebeli, Q., & Petri, R. M. (2019) · Anaerobe · doi:10.1016/j.anaerobe.2019.05.003 · Cited by 45 · see citing works
Methanogen Colonisation Does Not Significantly Alter Acetogen Diversity in Lambs Isolated 17 h After Birth and Raised Aseptically
Gagen, E. J., Mosoni, P., Denman, S. E., Jassim, R. A. M. A., McSweeney, C. S., & Forano, É. (2012) · Microbial Ecology · doi:10.1007/s00248-012-0024-z · Cited by 43 · see citing works
Epimural Indicator Phylotypes of Transiently-Induced Subacute Ruminal Acidosis in Dairy Cattle
Wetzels, S. U., Mann, E., Metzler-Zebeli, B. U., Pourazad, P., Qumar, M., Klevenhusen, F., Conrady, B., Wagner, M., Zebeli, Q., & Schmitz‐Esser, S. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00274 · Cited by 43 · see citing works
Changes in ruminal bacterial community composition following feeding of alfalfa ensiled with a lactic acid bacterial inoculant
Mohammed, R., Stevenson, D. M., Beauchemin, K. A., Muck, R. E., & Weimer, P. J. (2011) · Journal of Dairy Science · doi:10.3168/jds.2011-4492 · Cited by 43 · see citing works
Microbiome-driven breeding strategy potentially improves beef fatty acid profile benefiting human health and reduces methane emissions
Martínez-Álvaro, M., Mattock, J., Auffret, M. D., Weng, Z., Duthie, C.-A., Dewhurst, R. J., Cleveland, M. A., Watson, M., & Roehe, R. (2022) · Microbiome · doi:10.1186/s40168-022-01352-6 · Cited by 41 · see citing works
Effects of ruminal and post-ruminal protein supplementation in cattle fed tropical forages on insoluble fiber degradation, activity of fibrolytic enzymes, and the ruminal microbial community profile
dos Reis, W. L. S., Detmann, E., Batista, E. D., Rufino, L. M. A., Gomes, D. Í., Bento, C. B. P., Mantovani, H. C., & Filho, S. D. C. V. (2016) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2016.05.001 · Cited by 40 · see citing works
Impact of breed on the rumen microbial community composition and methane emission of Holstein Friesian and Belgian Blue heifers
Mulder, T. D., Peiren, N., Vandaele, L., Ruttink, T., Campeneere, S. D., de Wiele, T. V., & Goossens, K. (2017) · Livestock Science · doi:10.1016/j.livsci.2017.11.009 · Cited by 40 · see citing works
Host immune selection of rumen bacteria through salivary secretory IgA
Fouhse, J. M., Smiegielski, L., Tuplin, M., Guan, L. L., & Willing, B. P. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00848 · Cited by 37 · see citing works
Effects of direct-fed Bacillus subtilis and Bacillus licheniformis on production performance and milk fatty acid profile in dairy cows
Lamontagne, J., Rico, D. E., Perdomo, C. M., Ronholm, J., Gervais, R., & Chouinard, P. Y. (2023) · Journal of Dairy Science · doi:10.3168/jds.2022-22564 · Cited by 37 · see citing works
Bacterial communities in the rumen of Holstein heifers differ when fed orchardgrass as pasture vs. hay
Mohammed, R., Brink, G. E., Stevenson, D. M., Neumann, A. P., Beauchemin, K. A., Suen, G., & Weimer, P. J. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00689 · Cited by 37 · see citing works

1657 Changes in milk production efficiency and ruminal bacterial community composition following near-total exchange of ruminal contents between high- and low-efficiency Holstein cows
Weimer, P. J., Cox, M. S., Paula, T. V., Lin, M., & Suen, G. (2016) · Journal of Animal Science · doi:10.2527/jam2016-1657 · Cited by 5 · see citing works
Transient changes in milk production efficiency and bacterial community composition resulting from near-total exchange of ruminal contents between high- and low-efficiency Holstein cows
Weimer, P. J., Cox, M. S., Vieira de Paula, T., Lin, M., Hall, M. B., & Suen, G. (2017) · Journal of Dairy Science · doi:10.3168/jds.2017-12746 · Cited by 86 · see citing works
Data of bacterial community dynamics resulting from total rumen content exchange in beef cattle
Clemmons, B. A., Henniger, M. T., & Myer, P. R. (2021) · BMC Research Notes · doi:10.1186/s13104-021-05726-1 · Cited by 3 · see citing works
Cow responses and evolution of the rumen bacterial and methanogen community following a complete rumen content transfer
Mulder, T. D., Vandaele, L., Peiren, N., Haegeman, A., Ruttink, T., Campeneere, S. D., de Wiele, T. V., & Goossens, K. (2018) · The Journal of Agricultural Science · doi:10.1017/s0021859618001053 · Cited by 17 · see citing works
ARISA analysis of ruminal bacterial community dynamics in lactating dairy cows during the feeding cycle
Welkie, D. G., Stevenson, D. M., & Weimer, P. J. (2009) · Anaerobe · doi:10.1016/j.anaerobe.2009.07.002 · Cited by 137 · see citing works

Authors: Weimer, P. J., Stevenson, D. M., Mantovani, H. C., & Man, S. L. C.
Affiliations: Agricultural Research Service (US)
U.S. Dairy Forage Research Center (US)
Universidade Federal de Viçosa (BR)
University of Wisconsin–Madison (US)
Corresponding author: Weimer, P.J.
ORCID: Weimer, P.J.
Mantovani, H.C.
Venue: Journal of Dairy Science
Publisher: American Dairy Science Association
Published: 2010-12
Volume: 93
Issue: 12
Pages: 5902-5912
ISSN: 0022-0302 (ISSN-L)
DOI: 10.3168/jds.2010-3500
OpenAlex: W2126092649
Cited by: 267
References: 23
Citations by year: 2026: 16 · 2025: 19 · 2024: 17 · 2023: 12 · 2022: 22 · 2021: 16 · 2020: 21 · 2019: 22 · 2018: 27 · 2017: 23 · 2016: 15 · 2015: 18 · 2014: 15 · 2013: 13 · 2012: 7
FWCI: 15.63
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 2966 d)
Locations: Journal of Dairy Science (publishedVersion)
PubMed (publishedVersion)
Funders: University of Wisconsin-Madison
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Topics: Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Ruminant Nutrition and Digestive Physiology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Physical Sciences › Engineering › Building and Construction › Anaerobic Digestion and Biogas Production
Keywords: host specificity, dairy cattle, rumen pH, volatile fatty acids, microbial community stability, ARISA, rumen microbiota
MeSH terms: Animals, Cattle, Fatty Acids, Volatile, Hydrogen-Ion Concentration, Rumen, Host Specificity

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Host specificity of the ruminal bacterial community in the dairy cow following near-total exchange of ruminal contents

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks