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Cited by 343Ruminant Nutrition and Digestive PhysiologyAnimal Nutrition and PhysiologyGut microbiota and health

Manipulating rumen microbiome and fermentation through interventions during early life: a review

Open access
Yáñez-Ruiz, David R., Abecia, Leticia, Newbold, Charles J.·2015·Frontiers in Microbiology
DOI 10.3389/fmicb.2015.01133PMC PMC4604304
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Abstract

The nutritional manipulations of the rumen microbiome to enhance productivity and health are rather limited by the resilience of the ecosystem once established in the mature rumen. Based on recent studies, it has been suggested that the microbial colonization that occurs soon after birth opens a possibility of manipulation with potential to produce lasting effects into adult life. This paper presents the state-of-the-art in relation to early life nutritional interventions by addressing three areas: the development of the rumen as an organ in regards to the nutrition of the new-born, the main factors that determine the microbial population that first colonizes and establishes in the rumen, and the key immunity players that contribute to shaping the commensal microbiota in the early stage of life to understand host-microbiome specificity. The development of the rumen epithelium and muscularization are differently affected by the nature of the diet and special care should be taken with regards to transition from liquid (milk) to solid feed. The rumen is quickly colonized by all type of microorganisms straight after birth and the colonization pattern may be influenced by several factors such as presence/absence of adult animals, the first solid diet provided, and the inclusion of compounds that prevent/facilitate the establishment of some microorganisms or the direct inoculation of specific strains. The results presented show how early life events may be related to the microbial community structure and/or the rumen activity in the animals post-weaning. This would create differences in adaptive capacity due to different early life experiences and leads to the idea of microbial programming. However, many elements need to be further studied such as: the most sensitive window of time for interventions, the best means to test long term effectiveness, the role of key microbial groups and host-immune regulations.

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  • A better understanding of the roles played by the constituent microbes is central to the development of advanced methods to manipulate the rumen microbiome in a manner that improves ruminant production whilst reducing environmental impact.

    “A better understanding of the roles played by the constituent microbes is central to the development of advanced methods to manipulate the rumen microbiome in a manner that improves ruminant production whilst reducing environmental impact (Yáñez-Ruiz et al., 2015).”

    From Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future (2018) · cites this paper as Yáñez-Ruiz et al., 2015

  • Although the rumen microbiome establishes before intake of solid feeds, the type of feed consumed plays a significant role in shaping the established rumen microbiome.

    “It is important to note that although the rumen microbiome establishes before intake of solid feeds, the type of feed consumed plays a significant role in shaping the established rumen microbiome.”

    From Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future (2018) · cites this paper as Yáñez-Ruiz et al., 2015

  • The instability occurring during early life potentially allows for manipulation to assemble a specific community composition that persist later in life for better health and productivity within a given production system.

    “The instability occurring during this period potentially allows for manipulation to assemble a specific community composition that persist later in life for better health and productivity within a given production system (Yáñez-Ruiz et al., 2015).”

    From Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future (2018) · cites this paper as Yáñez-Ruiz et al., 2015

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2 of the 112 references couldn’t be matched to a known paper.

Research works printed but not linked: 3

  1. Davis C. L. Drackley J. K. (1998). The Development, Nutrition, and Management of the Young Calf. Ames, IA: Iowa State University Press.
  2. Dehority B. A. (2003). Rumen Microbiology. Nottingham: Nottingham University Press.
  3. Landy M. Weidanz W. P. (1964). “ Natural antibodies against gram negative bacteria,” in Bacterial Endotoxins, eds Landy M. Braun W. (New Brusnwick, NJ: Rutgers University Press).

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Authors
Yáñez-Ruiz, D. R., Abecia, L., & Newbold, C. J.
Affiliations
  • Consejo Superior de Investigaciones Científicas (ES)
  • Aberystwyth University (GB)
ORCID
Venue
Frontiers in Microbiology
Publisher
Frontiers Media SA
Published
2015-10-14
Volume
6
Pages
1133-1133
ISSN
1664-302X (ISSN-L)
DOI
10.3389/fmicb.2015.01133
PMC
PMC4604304
OpenAlex
W1894193924
Cited by
336
References
112
Citations by year
2026: 25 · 2025: 36 · 2024: 38 · 2023: 30 · 2022: 36 · 2021: 46 · 2020: 38 · 2019: 35 · 2018: 27 · 2017: 18 · 2016: 6 · 2015: 1
FWCI
3.02
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Microbiology (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
  • Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
  • Department for Environment, Food and Rural Affairs, UK Government
  • Directorate for Biological Sciences
  • Biotechnology and Biological Sciences Research Council (BBS/E/W/10964A01B, BB/J0013/1, grant number BB/J0013/1)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Ruminant Nutrition and Digestive Physiology
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords
rumen microbiome, rumen development, rumen epithelium, microbial colonization, host-microbiome interactions, immunity, weaning, direct inoculation, ruminant nutrition

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