Calf and dam characteristics and calf transport age affect immunoglobulin titers and hematological parameters of veal calves
Open accessAbstract
This study aimed to investigate effects of transport age of calves (14 vs. 28 d), and of calf and dam characteristics, on immunoglobulin titers and hematological variables of veal calves. Calves (n = 683) were transported to a veal farm at 14 or 28 d of age. Natural antibodies N-IgG, N-IgM, and N-IgA against phosphorylcholine conjugated to bovine serum albumin (PC-BSA) were measured in serum of the dams 1 wk before calving and in first colostrum. These antibodies were also measured in serum of calves 1 wk after birth, 1 d before transport, and in wk 2 and 10 posttransport at the veal farm. Hematological variables were assessed in calves 1 d before transport and in wk 2 posttransport. One day before transport, titers of N-IgG, N-IgM, N-IgA, and neutrophil counts were higher, and lymphocyte counts were lower in 14-d-old calves compared with 28-d-old calves. In wk 2 at the veal farm, calves transported at 14 d of age had higher N-IgG titers and neutrophil counts, but lower N-IgM and N-IgA titers, and lymphocyte counts than calves transported at 28 d. In wk 1 and 1 d before transport, N-Ig in calves were positively related to N-Ig in colostrum. In wk 2 and 10 at the veal farm, N-IgG in calves was positively related to N-IgG in colostrum. The N-IgG titers in calves at the dairy farm were negatively related to the likelihood of being individually treated with antibiotics or other medicines at the veal farm. Our results suggest that calves transported to the veal farm at 28 d of age showed a more advanced development of their adaptive immunity than calves transported at 14 d of age. Quality of colostrum might have long-term consequences for N-IgG titers and immunity in veal calves.
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Most of the available research on the impact of transport on calves of different ages is based on experimental or observational data and focuses on young calves aged less than 28 days.
“Most of the available research on the impact of transport on calves of different ages is based on experimental or observational data and focuses on young calves aged less than 28 days [28–31].”
From Effects of age and feeding protocols on the metabolic and physiological condition of unweaned calves during and after long-distance transport (2026) · cites this paper as [31]
The Experimental Design section describes an experiment comparing calves transported at approximately 14 and 28 days of age, and the Introduction mentions previous transport and observational studies. But the paper does not establish that most available research focuses on calves younger than 28 days; its own comparison includes a 28-day group. Page numbers are unavailable in our copy. (LLM, conf=0.76)
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Welfare of cattle during transport
(AHAW), E. P. O. A. H. A. W., Nielsen, S. S., Alvarez, J., Bicout, D. J., Calistri, P., Canali, E., Drewe, J. A., Garin‐Bastuji, B., Gonzales Rojas, J. L., Gortázar Schmidt, C., et al. (2022) · EFSA Journal · doi:10.2903/j.efsa.2022.7442 · Cited by 64 · see citing works
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“Most of the available research on the impact of transport on calves of different ages is based on experimental or observational data and focuses on young calves aged less than 28 days [28–31].”
- Authors
- Marcato, F., van den Brand, H., Kemp, B., Engel, B., Schnabel, S. K., Jansen, C. A., Rutten, V. P. M. G., Koets, A. P., Hoorweg, F. A., de Vries-Reilingh, G., Wulansari, A., Wolthuis-Fillerup, M., & van Reenen, K.
- Affiliations
- Wageningen University & Research (NL)
- Utrecht University (NL)
- Corresponding author
- Marcato, F.
- ORCID
- Venue
- Journal of Dairy Science
- Publisher
- American Dairy Science Association
- Published
- 2022-02
- Volume
- 105
- Issue
- 2
- Pages
- 1432-1451
- ISSN
- 0022-0302 (ISSN-L)
- OpenAlex
- W3215535813
- Cited by
- 24
- References
- 50
- Citations by year
- 2026: 5 · 2025: 1 · 2024: 5 · 2023: 3 · 2022: 9 · 2021: 1
- FWCI
- 5.14
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of Dairy Science (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Socio-Environmental Systems Modeling (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- UpSpace Institutional Repository (University of Pretoria) (submittedVersion, cc-by)
- Data Archiving and Networked Services (DANS) (submittedVersion, cc-by-nc-nd)
- Funders
- Ketenorganisatie van de zuivelsector
- Ministerie van Landbouw, Natuur en Voedselkwaliteit
- Wageningen University and Research
- Topics
- Health Sciences › Veterinary › Small Animals › Animal health and immunology
- Health Sciences › Veterinary › Small Animals › Animal Behavior and Welfare Studies
- Life Sciences › Immunology and Microbiology › Microbiology › Microbial infections and disease research
- Keywords
- veal calves, natural antibodies, IgG, immunoglobulin M, immunoglobulin A, colostrum, hematological parameters, neutrophil count, lymphocyte count, antibiotic therapy
- MeSH terms
- Red Meat, Farms, Animals, Animals, Newborn, Cattle, Colostrum, Female, Immunoglobulin G, Pregnancy
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