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Matrix metalloproteinases in Alzheimer’s disease and concurrent cerebral microbleeds.
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Duits and collaborators reported decreases in TIMP-2 (and also TIMP-1) in the CSF of AD patients with microbleeds.
“Duits and collaborators reported decreases in TIMP-2 (and also TIMP-1) in the CSF of AD patients with microbleeds (Duits et al., 2015).”
From Emerging Alternative Proteinases in APP Metabolism and Alzheimer’s Disease Pathogenesis: A Focus on MT1-MMP and MT5-MMP (2019) · cites this paper as Duits et al., 2015
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Gorelick, P. B., Scuteri, A., Black, S. E., DeCarli, C., Greenberg, S. M., Iadecola, C., Launer, L. J., Laurent, S., Lopez, O. L., Nyenhuis, D., et al. (2011) · Stroke · doi:10.1161/str.0b013e3182299496 · Cited by 3,811
Cerebral microbleeds: a guide to detection and interpretation
Greenberg, S. M., Vernooij, M. W., Cordonnier, C., Viswanathan, A., Al-Shahi Salman, R., Warach, S., Launer, L. J., Van Buchem, M. A., & Breteler, M. M. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70013-4 · Cited by 1,798
Matrix metalloproteinases and their multiple roles in neurodegenerative diseases
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Matrix Metalloproteinase-9 Degrades Amyloid-β Fibrils in Vitro and Compact Plaques in Situ
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“Post-hoc tests showed higher CSF MMP10 levels in AD patients compared to controls (median [IQR] 25 [16–35] versus 13 [10–20] pg/mL, p= 0.”
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Metadata
- Authors
- Duits, F. H., Hernandez-Guillamon, M., Montaner, J., Goos, J. D. C., Montañola, A., Wattjes, M. P., Barkhof, F., Scheltens, P., Teunissen, C. E., & van der Flier, W. M.
- Affiliations
- Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
- Neurovascular Research Laboratory, Institut de Recerca, Barcelona, Spain
- Department of Radiology & Nuclear Medicine, Neuroscience Campus Amsterdam,VU University Medical Center, Amsterdam, The Netherlands
- Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
- Venue
- Journal of Alzheimer's Disease
- Publisher
- SAGE Publications
- Published
- 2015-10-01
- Volume
- 48
- Issue
- 3
- Pages
- 711-720
- ISSN
- 1387-2877
- 1875-8908
- Cited by
- 92
- References
- 7
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