The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
Relative incidence of seizures and myoclonus in Alzheimer’s disease, dementia with lewy bodies, and frontotemporal dementia.
Open accessAbstract
BACKGROUND: Patients with Alzheimer's disease (AD) are more prone to seizures and myoclonus, but relative risk of these symptoms among other dementia types is unknown. OBJECTIVE: To determine incidence of seizures and myoclonus in the three most common neurodegenerative dementias: AD, dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD). METHODS: Our institution's medical records were reviewed for new-onset unprovoked seizures and myoclonus in patients meeting criteria for AD (n = 1,320), DLB (n = 178), and FTD (n = 348). Cumulative probabilities of developing seizures and myoclonus were compared between diagnostic groups, whereas age-stratified incidence rates were determined relative to control populations. RESULTS: The cumulative probability of developing seizures after disease onset was 11.5% overall, highest in AD (13.4%) and DLB (14.7%) and lowest in FTD (3.0%). The cumulative probability of developing myoclonus was 42.1% overall, highest in DLB (58.1%). The seizure incidence rates, relative to control populations, were nearly 10-fold in AD and DLB, and 6-fold in FTD. Relative seizure rates increased with earlier age-at-onset in AD (age <50, 127-fold; 50-69, 21-fold; 70+, 2-fold) and FTD (age <50, 53-fold; 50-69, 9-fold), and relative myoclonus rates increased with earlier age-at-onset in all groups. Seizures began an average of 3.9 years after the onset of cognitive or motor decline, and myoclonus began 5.4 years after onset. CONCLUSIONS: Seizures and myoclonus occur with greater incidence in patients with AD, DLB, and FTD than in the general population, but rates vary with diagnosis, suggesting varied pathomechanisms of network hyperexcitability. Patients often experience these symptoms early in disease, suggesting hyperexcitability could be an important target for interventions.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“However, the possibility of seizures and hyperexcitability in primary tauopathies should not be ruled out, as they occur more frequently in these diseases than in the general population (Beagle et al., 2017; Sanchez et al., 2018).”
From Tauopathy and Epilepsy Comorbidities and Underlying Mechanisms (2022) · cites this paper as Beagle et al., 2017
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Seizures are more common in AD and dementia with Lewy bodies than in primary tauopathies, such as frontotemporal dementia and progressive supranuclear palsy (Beagle et al., 2017).”
From Tauopathy and Epilepsy Comorbidities and Underlying Mechanisms (2022) · cites this paper as Beagle et al., 2017
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“A mechanism by which epileptogenesis gives rise to tau hyperphosphorylation may underlie the high incidence of tauopathy and epilepsy co-pathology that is found in diseases such as AD and dementia with Lewy bodies (Vossel et al., 2016, 2017; Beagle et al., 2017).”
From Tauopathy and Epilepsy Comorbidities and Underlying Mechanisms (2022) · cites this paper as Beagle et al., 2017
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., Klunk, W. E., Koroshetz, W. J., Manly, J. J., Mayeux, R., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.005 · Cited by 18,657
Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy
Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
Rascovsky, K., Hodges, J. R., Knopman, D., Mendez, M. F., Kramer, J. H., Neuhaus, J., van Swieten, J. C., Seelaar, H., Dopper, E. G. P., Onyike, C. U., et al. (2011) · Brain · doi:10.1093/brain/awr179 · Cited by 5,221
Classification of primary progressive aphasia and its variants
Gorno-Tempini, M. L., Hillis, A. E., Weintraub, S., Kertesz, A., Mendez, M., Cappa, S. F., Ogar, J. M., Rohrer, J. D., Black, S., Boeve, B. F., et al. (2011) · Neurology · doi:10.1212/wnl.0b013e31821103e6 · Cited by 5,141
Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium
McKeith, I. G., Dickson, D. W., Lowe, J., Emre, M., O'Brien, J. T., Feldman, H., Cummings, J., Duda, J. E., Lippa, C., Perry, E. K., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000187889.17253.b1 · Cited by 5,069
Berg, A. T., Berkovic, S. F., Brodie, M. J., Buchhalter, J., Cross, J. H., Van Emde Boas, W., Engel, J., French, J., Glauser, T. A., Mathern, G. W., et al. (2010) · Epilepsia · doi:10.1111/j.1528-1167.2010.02522.x · Cited by 4,363
TREM2 Variants in Alzheimer's Disease
Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J. S. K., Younkin, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211851 · Cited by 3,020
Weıntraub, S. (1990) · Archives of Neurology · doi:10.1001/archneur.1990.00530120075013 · Cited by 3,018
Appelhof, B., Bakker, C., den IJssel, J. C. L. V. D., Zwijsen, S. A., Smalbrugge, M., Verhey, F. R. J., de Vugt, M. E., Zuidema, S. U., & Koopmans, R. T. C. M. (2017) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000477087 · Cited by 2,774
Litvan, I., Agid, Y., Calne, D., Campbell, G., Dubois, B., Duvoisin, R. C., Goetz, C. G., Golbe, L. I., Grafman, J., Growdon, J. H., et al. (1996) · Neurology · doi:10.1212/wnl.47.1.1 · Cited by 2,538
Qualitative Assessment of Verbal Fluency Performance in Frontotemporal Dementia
van den Berg, E., Jiskoot, L. C., Grosveld, M. J. H., Swieten, J. C. V., & Papma, J. M. (2017) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000477538 · Cited by 2,065
Criteria for the diagnosis of corticobasal degeneration
Armstrong, M. J., Litvan, I., Lang, A. E., Bak, T. H., Bhatia, K. P., Borroni, B., Boxer, A. L., Dickson, D. W., Grossman, M., Hallett, M., et al. (2013) · Neurology · doi:10.1212/wnl.0b013e31827f0fd1 · Cited by 1,904
Palop, J. J., Chin, J., Roberson, E. D., Wang, J., Thwin, M. T., Bien-Ly, N., Yoo, J., Ho, K. O., Yu, G.-Q., Kreitzer, A., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.07.025 · Cited by 1,653
Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
Palop, J. J., & Mucke, L. (2010) · Nature Neuroscience · doi:10.1038/nn.2583 · Cited by 1,651
Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo
Cirrito, J. R., Yamada, K. A., Finn, M. B., Sloviter, R. S., Bales, K. R., May, P. C., Schoepp, D. D., Paul, S. M., Mennerick, S., & Holtzman, D. M. (2005) · Neuron · doi:10.1016/j.neuron.2005.10.028 · Cited by 1,265
Neuronal activity enhances tau propagation and tau pathology in vivo
Wu, J. W., Hussaini, S. A., Bastille, I. M., Rodriguez, G. A., Mrejeru, A., Rilett, K., Sanders, D. W., Cook, C., Fu, H., Boonen, R. A. C. M., et al. (2016) · Nature Neuroscience · doi:10.1038/nn.4328 · Cited by 820
Barker, W., Luis, C. A., Kashuba, A., Luis, M., Harwood, D. G., Loewenstein, D., Waters, C., Jimison, P., Shepherd, E., Sevush, S., et al. (2002) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-200210000-00001 · Cited by 714
Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease
Vossel, K. A., Beagle, A. J., Rabinovici, G., Shu, H., Lee, S. E., Naasan, G., Hegde, M., Cornes, S., Henry, M., Nelson, A. B., et al. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.136 · Cited by 709
Self-citationPrevalence of Amyloid PET Positivity in Dementia Syndromes: A Meta-analysis
Ossenkoppele, R., Jansen, W. J., Rabinovici, G. D., Knol, D. L., van der Flier, W. M., van Berckel, B. N. M., Scheltens, P., Visser, P. J., Verfaillie, S. C. J., Zwan, M. D., et al. (2015) · JAMA · doi:10.1001/jama.2015.4669 · Cited by 677
Roberson, E. D., Halabisky, B., Yoo, J. W., Yao, J., Chin, J., Yan, F., Wu, T., Hamto, P., Devidze, N., Yu, G.-Q., et al. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4152-10.2011 · Cited by 654
Masliah, E., Rockenstein, E., Veinbergs, I., Sagara, Y., Mallory, M., Hashimoto, M., & Mucke, L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211412398 · Cited by 607
Incidence and Predictors of Seizures in Patients with Alzheimer's Disease
Amatniek, J. C., Hauser, W. A., del Castillo–Castañeda, C., Jacobs, D. M., Marder, K. S., Bell, K. L., Albert, M., Brandt, J., & Stern, Y. (2006) · Epilepsia · doi:10.1111/j.1528-1167.2006.00554.x · Cited by 592
Epileptic activity in Alzheimer’s disease: Causes and clinical relevance
Vossel, K. A., Tartaglia, M. C., Nygaard, H. B., Zeman, A. Z., & Miller, B. L. (2017) · The Lancet Neurology · doi:10.1016/s1474-4422(17)30044-3 · Cited by 590
Self-citationIncidence and impact of subclinical epileptiform activity in Alzheimer’s disease.
Vossel, K. A., Ranasinghe, K. G., Beagle, A. J., Mizuiri, D., Honma, S. M., Dowling, A. F., Darwish, S. M., Van Berlo, V., Barnes, D. E., Mantle, M., et al. (2016) · Annals of Neurology · doi:10.1002/ana.24794 · Cited by 557
Self-citationClinicopathological correlations in corticobasal degeneration
Lee, S. E., Rabinovici, G. D., Mayo, M. C., Wilson, S. M., Seeley, W. W., DeArmond, S. J., Huang, E. J., Trojanowski, J. Q., Growdon, M. E., Jang, J. Y., et al. (2011) · Annals of Neurology · doi:10.1002/ana.22424 · Cited by 434
Silent hippocampal seizures and spikes identified by foramen ovale electrodes in Alzheimer's disease
Lam, A. D., Deck, G. M., Goldman, A. M., Eskandar, E. N., Noebels, J. L., & Cole, A. J. (2017) · Nature Medicine · doi:10.1038/nm.4330 · Cited by 369
Forsgren, L., Bucht, G., Eriksson, S., & Bergmark, L. (1996) · Epilepsia · doi:10.1111/j.1528-1157.1996.tb00017.x · Cited by 360
Effects of Psychotropic Drugs on Seizure Threshold
Pisani, F., Oteri, G., Costa, C., Raimondo, G. D., & Perri, R. D. (2002) · Drug Safety · doi:10.2165/00002018-200225020-00004 · Cited by 359
Seizures and myoclonus in patients with Alzheimer's disease
Hauser, W. A., Morris, M. L., Heston, L. L., & Anderson, V. E. (1986) · Neurology · doi:10.1212/wnl.36.9.1226 · Cited by 336
Is the Risk of Developing Alzheimer's Disease Greater for Women than for Men?
Hebert, L. E., Scherr, P. A., McCann, J. J., Beckett, L. A., & Evans, D. A. (2001) · American Journal of Epidemiology · doi:10.1093/aje/153.2.132 · Cited by 331 · cited 1×
“For example, sex distributions are in line with previous reports in patients with neurodegenerative diseases [57, 58], and rates of amyloid PET positivity in patients with AD and FTD are consistent with results from broader dementia populations [59].”
Andrews-Zwilling, Y., Bien-Ly, N., Xu, Q., Li, G., Bernardo, A., Yoon, S. Y., Zwilling, D., Yan, T. X., Chen, L., & Huang, Y. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4040-10.2010 · Cited by 326
The pathological basis of semantic dementia
Davies, R. R., Hodges, J. R., Kril, J. J., Patterson, K., Halliday, G. M., & Xuereb, J. H. (2005) · Brain · doi:10.1093/brain/awh582 · Cited by 325
Dementia and adult-onset unprovoked seizures
Hesdorffer, D. C., Hauser, W. A., Annegers, J. F., Kokmen, E., & Rocca, W. A. (1996) · Neurology · doi:10.1212/wnl.46.3.727 · Cited by 311
Frontotemporal dementia progresses to death faster than Alzheimer disease
Roberson, E. D., Hesse, J., Rose, K. D., Slama, H., Johnson, J. K., Yaffe, K. S., Forman, M. S., Miller, C. A., Trojanowski, J. Q., Kramer, J. H., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000173837.82820.9f · Cited by 297
Bakker, A., Albert, M., Krauss, G. L., Speck, C. L., & Gallagher, M. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2015.02.009 · Cited by 295
Scarmeas, N., Honig, L. S., Choi, H., Cantero, J., Brandt, J., Blacker, D., Albert, M., Amatniek, J. C., Marder, K. S., Bell, K. L., et al. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.130 · Cited by 293
Noebels, J. L. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2010.02909.x · Cited by 261
Advanced Alzheimer's Disease Is a Risk Factor for Late-Onset Seizures
Romanelli, M. F., Morris, J. C., Ashkin, K., & Coben, L. A. (1990) · Archives of Neurology · doi:10.1001/archneur.1990.00530080029006 · Cited by 242
Coppola, G., Chinnathambi, S., Lee, J. J., Dombroski, B. A., Baker, M. C., Soto-Ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds161 · Cited by 240
Cumbo, E., & Ligori, L. D. (2010) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.01.015 · Cited by 216
NMDA Receptor Activation Inhibits α-Secretase and Promotes Neuronal Amyloid-β Production
Lesné, S., Ali, C., Gabriel, C., Croci, N., MacKenzie, E. T., Glabe, C. G., Plotkine, M., Marchand‐Leroux, C., Vivien, D., & Buisson, A. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0849-05.2005 · Cited by 211
Cruchaga, C., Graff, C., Chiang, H., Wang, J., Hinrichs, A. L., Spiegel, N., Bertelsen, S. E., Mayo, K., Norton, J. B., Morris, J. C., et al. (2011) · Archives of Neurology · doi:10.1001/archneurol.2010.350 · Cited by 189
Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model
Schoch, K. M., DeVos, S. L., Miller, R. L., Chun, S. J., Norrbom, M., Wozniak, D. F., Dawson, H. N., Bennett, C. F., Rigo, F., & Miller, T. M. (2016) · Neuron · doi:10.1016/j.neuron.2016.04.042 · Cited by 175
Louis, E. D., Klatka, L. A., Liu, Y., & Fahn, S. (1997) · Neurology · doi:10.1212/wnl.48.2.376 · Cited by 169
Ranasinghe, K. G., Rankin, K. P., Pressman, P. S., Perry, D. C., Lobach, I. V., Seeley, W. W., Coppola, G., Karydas, A. M., Grinberg, L. T., Shany-Ur, T., et al. (2016) · JAMA Neurology · doi:10.1001/jamaneurol.2016.2016 · Cited by 151
Self-citationExpression of A152T human tau causes age‐dependent neuronal dysfunction and loss in transgenic mice
Maeda, S., Djukic, B., Taneja, P., Yu, G.-Q., Lo, I., Davis, A., Craft, R., Guo, W., Wang, X., Kim, D., et al. (2016) · EMBO Reports · doi:10.15252/embr.201541438 · Cited by 133
Prevalence and Causes of Seizures at the Time of Diagnosis of Probable Alzheimer’s Disease
Lozsádi, D. A., & Larner, A. J. (2006) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000093664 · Cited by 131
Effect of Seizures on Progression of Dementia of the Alzheimer Type
Volicer, L., Smith, S. J., & Volicer, B. J. (1995) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000106956 · Cited by 129
Cretin, B., Sellal, F., Philippi, N., Bousiges, O., Bitonto, L. D., Martin‐Hunyadi, C., & Blanc, F. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150096 · Cited by 125
Baldin, E., Hauser, W. A., Buchhalter, J., Hesdorffer, D. C., & Ottman, R. (2014) · Epilepsia · doi:10.1111/epi.12720 · Cited by 124
Breteler, M. M. B., de Groot, R. R. M., van Romunde, L. K. J., & Albert Hofman, D. (1995) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a117597 · Cited by 121
Hyperexcitability and epileptic seizures in a model of frontotemporal dementia.
García-Cabrero, A. M., Guerrero-López, R., Giraldez, B., Llorens-Martín, M., Ávila, J., Serratosa, J., & Sánchez, M. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.06.005 · Cited by 98
Down Syndrome and Dementia: Seizures and Cognitive Decline
Lott, I. T., Doran, E. W., Nguyen, V. Q., Tournay, A. E., Movsesyan, N., & Gillen, D. L. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-111613 · Cited by 95
rs5848 polymorphism and serum progranulin level
Hsiung, G. R., Fok, A., Feldman, H., Rademakers, R., & Mackenzie, I. R. (2010) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2010.10.009 · Cited by 87
The Incidence and Prevalence of Myoclonus in Olmsted County, Minnesota
Caviness, J. N., Alving, L. I., Maraganore, D. M., Black, R. A., McDonnell, S. K., & Rocca, W. A. (1999) · Mayo Clinic Proceedings · doi:10.4065/74.6.565 · Cited by 78
Sarkis, R. A., Dickerson, B. C., Cole, A. J., & Chemali, Z. N. (2015) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.15060143 · Cited by 75
Seizures and dementia in the elderly: Nationwide Inpatient Sample 1999–2008
Sherzai, D., Losey, T. E., Vega, S., & Sherzai, A. Z. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.04.015 · Cited by 68
Network dysfunction in α‐synuclein transgenic mice and human Lewy body dementia
Morris, M., Sanchez, P. E., Verret, L., Beagle, A. J., Guo, W., Dubal, D., Ranasinghe, K. G., Koyama, A., Ho, K., Yu, G., et al. (2015) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.257 · Cited by 61
Self-citationClinical Features and Mortality in Patients with Early-Onset Alzheimer’s Disease
Samson, W. N., van Duijn, C. M., Hop, W. C. J., & Albert Hofman, D. (2008) · European Neurology · doi:10.1159/000117218 · Cited by 58
Onset of seizures as a poor indicator of longevity in people with down syndrome and dementia
Prasher, V. P., & Corbett, J. A. (1993) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.930081106 · Cited by 34
Robinson, A., Thompson, J. C., Weedon, L., Rollinson, S. J., Pickering-Brown, S. M., Snowden, J. S., Davidson, Y. S., & Mann, D. M. A. (2014) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12155 · Cited by 25
Research works printed but not linked: 1
- Rothman, 2008, Modern Epidemiology
Cited by
Sorted by citations
Targa Dias Anastacio, H., Matosin, N., & Ooi, L. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02024-7 · Cited by 401
Biological aging processes underlying cognitive decline and neurodegenerative disease
Gonzales, M. M., Garbarino, V. R., Pollet, E., Palavicini, J. P., Kellogg, D. L., Kraig, E., & Orr, M. E. (2022) · Journal of Clinical Investigation · doi:10.1172/jci158453 · Cited by 426
Vossel, K. A., Ranasinghe, K. G., Beagle, A. J., La, A. L., Pook, K. A., Castro, M. R., Mizuiri, D., Honma, S. M., Venkateswaran, N., KOESTLER, M. E., et al. (2021) · JAMA Neurology · doi:10.1001/jamaneurol.2021.3310 · Cited by 277
Self-citationJiménez-Baladó, J., & Eich, T. S. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.01.005 · Cited by 194
Bowles, K. R., Silva, M. C., Whitney, K., Bertucci, T., Berlind, J. E., Lai, J. D., Garza, J. C., Boles, N. C., Mahali, S., Strang, K. H., et al. (2021) · Cell · doi:10.1016/j.cell.2021.07.003 · Cited by 175
Metadata
- Authors
- Beagle, A. J., Darwish, S. M., Ranasinghe, K. G., La, A. L., Karageorgiou, E., & Vossel, K. A.
- Affiliations
- University of California, San Francisco (US)
- University of Minnesota (US)
- Corresponding author
- Vossel, Keith A.
- Venue
- Journal of Alzheimer's Disease
- Publisher
- SAGE Publications
- Published
- 2017-08-29
- Volume
- 60
- Issue
- 1
- Pages
- 211-223
- ISSN
- 1387-2877 (ISSN-L)
- 1875-8908
- PMC
- PMC5608587
- OpenAlex
- W2746678792
- Cited by
- 173
- References
- 62
- Citations by year
- 2026: 18 · 2025: 24 · 2024: 27 · 2023: 17 · 2022: 17 · 2021: 25 · 2020: 27 · 2019: 10 · 2018: 8
- FWCI
- 10.11
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Alzheimer s Disease (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- University of California, San Francisco
- National Institute on Aging (K23AG038357, F32AG050434)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Keywords
- Alzheimer's disease, dementia with Lewy bodies
- MeSH terms
- Aged, Alzheimer Disease, Female, Humans, Male, Middle Aged, Myoclonus, Psychiatric Status Rating Scales, Retrospective Studies, Seizures, Severity of Illness Index, Incidence, Age Distribution, Lewy Body Disease, Frontotemporal Dementia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
